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Molecular and Cellular Biology Volume 18, 1998 - Issue 5
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Transcriptional Regulation

Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun

Alexander Zagariyaa Department of Medicine, Division of Arthritis, and Veterans Administration Lakeside Medical Center
,
Shubhangee Mungrea Department of Medicine, Division of Arthritis, and Veterans Administration Lakeside Medical Center
,
Rosa Lovisa Department of Medicine, Division of Arthritis, and Veterans Administration Lakeside Medical Center
,
Michael Birrerc Department of Cell and Cancer Biology, National Cancer Institute, National Institutes of Health, Rockville, Maryland20805
,
Scott Nessd Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois60208-3500
,
Bayar Thimmapayab Department of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois60611
&
Richard Popea Department of Medicine, Division of Arthritis, and Veterans Administration Lakeside Medical CenterCorrespondence[email protected]
 show all
Pages 2815-2824 | Received 05 Nov 1997, Accepted 12 Feb 1998, Published online: 28 Mar 2023

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P. Kathiravan, S. Goyal, R.S. Kataria, B.P. Mishra, S. Jayakumar & B.K. Joshi. (2011) Sequence Characterization of S100A8 Gene Reveals Structural Differences of Protein and Transcriptional Factor Binding Sites in Water Buffalo and Yak. Animal Biotechnology 22:3, pages 124-132.
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Arántzazu Alfranca, M. Dolores Gutiérrez, Alicia Vara, Julián Aragonés, Felipe Vidal & Manuel O. Landázuri. (2002) c-Jun and Hypoxia-Inducible Factor 1 Functionally Cooperate in Hypoxia-Induced Gene Transcription. Molecular and Cellular Biology 22:1, pages 12-22.
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Mariano Ubeda, Mario Vallejo & Joel F. Habener. (1999) CHOP Enhancement of Gene Transcription by Interactions with Jun/Fos AP-1 Complex Proteins. Molecular and Cellular Biology 19:11, pages 7589-7599.
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Teri L Wadsworth, Tasha L McDonald & Dennis R Koop. (2001) Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α 1 1Abbreviations: EGb 761, Ginkgo biloba extract; LPS, lipopolysaccharide; ROIs, reactive oxygen intermediates; TNF, tumor necrosis factor; IL, interleukin; COX, cyclooxygenase; iNOS, inducible nitric oxide synthase; TLR, Toll-like receptor; LBP, lipid binding protein; NF-κB, nuclear factor-κB; IKK, IκB kinase; AP-1, activator protein 1; ATF, activating transcription factor; CRE, cyclic AMP response element; CREB, cyclic AMP binding protein; C/EBP, CCAAT/enhancer binding protein; ARE, AU-rich element; -UTR, untranslated region; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-related kinase; MEKK, MAPK/ERK kinase kinase; MEK, MAPK/ERK kinase; JNK/SAPK, Jun N terminal kinase/stress-activated protein kinase; EMSA, electrophoretic mobility shift assay; DTT, dithiothreitol; PMSF, phenylmethylsulfonyl fluoride; and ECL, enhanced chemiluminescence.. Biochemical Pharmacology 62:7, pages 963-974.
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Jörg-Dieter Schulzke & Michael Fromm. 2001. Tight Junctions. Tight Junctions.
Jean-Pierre Bayley, Henny de Rooij, Peter J. van Den Elsen, Tom W.J. Huizinga & Cornelis L. Verweij. (2001) FUNCTIONAL ANALYSIS OF LINKER-SCAN MUTANTS SPANNING THE −376, −308, −244, AND −238 POLYMORPHIC SITES OF THE TNF-α PROMOTER. Cytokine 14:6, pages 316-323.
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Chen Zhu, Khatuna Gagnidze, James H.M. Gemberling & Scott E. Plevy. (2001) Characterization of an Activation Protein-1-binding Site in the Murine Interleukin-12 p40 Promoter. Journal of Biological Chemistry 276:21, pages 18519-18528.
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Peter Angel, Axel Szabowski & Marina Schorpp-Kistner. (2001) Function and regulation of AP-1 subunits in skin physiology and pathology. Oncogene 20:19, pages 2413-2423.
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Mark Gagliardi, Scott Maynard, Bojana Bojovic & Pierre-André Bédard. (2001) The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts. Oncogene 20:18, pages 2301-2313.
Crossref
P Sidiropoulos, H Liu, S Mungre, L Anderson, B Thimmapaya & RM Pope. (2001) Efficacy of adenoviral TNFα antisense is enhanced by a macrophage specific promoter. Gene Therapy 8:3, pages 223-231.
Crossref
Constantinos Georganas, Hongtao Liu, Harris Perlman, Alexander Hoffmann, Bayar Thimmapaya & Richard M. Pope. (2000) Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-κB But Not C/EBPβ or c-Jun. The Journal of Immunology 165:12, pages 7199-7206.
Crossref
Belisa DiazGabriel Lopez-Berestein. (2000) A Distinct Element Involved in Lipopolysaccharide Activation of the Tumor Necrosis Factor-α Promoter in Monocytes. Journal of Interferon & Cytokine Research 20:8, pages 741-748.
Crossref
Richard Pope, Shubangee Mungre, Hongtao Liu & Bayar Thimmapaya. (2000) REGULATION OF TNF-α EXPRESSION IN NORMAL MACROPHAGES: THE ROLE OF C/EBPβ. Cytokine 12:8, pages 1171-1181.
Crossref
J. MankertzS. TavalaliH. SchmitzA. MankertzE.O. RieckenM. FrommJ.D. Schulzke. (2000) Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. Journal of Cell Science 113:11, pages 2085-2090.
Crossref
James H. Steer, Karen M. Kroeger, Lawrence J. Abraham & David A. Joyce. (2000) Glucocorticoids Suppress Tumor Necrosis Factor-α Expression by Human Monocytic THP-1 Cells by Suppressing Transactivation through Adjacent NF-κB and c-Jun-Activating Transcription Factor-2 Binding Sites in the Promoter. Journal of Biological Chemistry 275:24, pages 18432-18440.
Crossref
Mausumee Guha, Wei Bai, Jerry L. Nadler & Rama Natarajan. (2000) Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways. Journal of Biological Chemistry 275:23, pages 17728-17739.
Crossref
Hongtao Liu, Prodromos Sidiropoulos, Guobin Song, Lisa J. Pagliari, Michael J. Birrer, Bernd Stein, Josef Anrather & Richard M. Pope. (2000) TNF-α Gene Expression in Macrophages: Regulation by NF-κB Is Independent of c-Jun or C/EBPβ. The Journal of Immunology 164:8, pages 4277-4285.
Crossref
Daniel H Li, Edward A Havell, Cynthia L Brown & John M Cullen. (2000) Woodchuck lymphotoxin-α, -β and tumor necrosis factor genes: structure, characterization and biological activity. Gene 242:1-2, pages 295-305.
Crossref
Ulrich Blank & Nadine Varin-Blank. 2000. Mast Cells and Basophils. Mast Cells and Basophils 149 167 .
Mary Lee MacKichan & Anthony L. DeFranco. 2000. Novel Cytokine Inhibitors. Novel Cytokine Inhibitors 9 42 .
Sachiko Okabe, Yumiko Ochiai, Miwa Aida, Keunchil Park, Seong-Jin Kim, Taro Nomura, Masami Suganuma & Hirota Fujiki. (1999) Mechanistic Aspects of Green Tea as a Cancer Preventive: Effect of Components on Human Stomach Cancer Cell Lines. Japanese Journal of Cancer Research 90:7, pages 733-739.
Crossref
David L. Williams, Tuanzhu Ha, Chuanfu Li, John H. Kalbfleisch & Donald A. FergusonJr.Jr.. (1999) Early Activation of Hepatic NFκB and NF-IL6 in Polymicrobial Sepsis Correlates With Bacteremia, Cytokine Expression, and Mortality. Annals of Surgery 230:1, pages 95.
Crossref
David L. Williams, Tuanzhu Ha, Chaunfu Li, John H. Kalbfleisch, John J. Laffan & Donald A. Ferguson. (1999) Inhibiting early activation of tissue nuclear factor-κB and nuclear factor interleukin 6 with (1→3)-β-D -glucan increases long-term survival in polymicrobial sepsis. Surgery 126:1, pages 54-65.
Crossref
Robert C. Newton & Carl P. Decicco. (1999) Therapeutic Potential and Strategies for Inhibiting Tumor Necrosis Factor-α. Journal of Medicinal Chemistry 42:13, pages 2295-2314.
Crossref
Richard M. Pope, Rosa Lovis, Shubhangee Mungre, Harris Perlman, Alisa E. Koch & G.Kenneth HainesIIIIII. (1999) C/EBPβ in Rheumatoid Arthritis: Correlation with Inflammation, Not Disease Specificity1. Clinical Immunology 91:3, pages 271-282.
Crossref
Vladimir N. Ivanov & Ze'ev Ronai. (1999) Down-regulation of Tumor Necrosis Factor α Expression by Activating Transcription Factor 2 Increases UVC-induced Apoptosis of Late-stage Melanoma Cells. Journal of Biological Chemistry 274:20, pages 14079-14089.
Crossref
Ingrid Herr, Ana Martin-Villalba, Elke Kurz, Paola Roncaioli, Johannes Schenkel, Maria Grazia Cifone & Klaus-Michael Debatin. (1999) FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. Brain Research 826:2, pages 210-219.
Crossref
Angelika Hoffmeyer, Anne Grosse-Wilde, Egbert Flory, Bernd Neufeld, Manfred Kunz, Ulf R. Rapp & Stephan Ludwig. (1999) Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes. Journal of Biological Chemistry 274:7, pages 4319-4327.
Crossref
Ingrid Herr, Dagmar Wilhelm, Thomas B�hler, Peter Angel & Klaus-Michael Debatin. (1999) JNK/SAPK activity is not sufficient for anticancer therapy-induced apoptosis involving CD95-L, TRAIL and TNF-?. International Journal of Cancer 80:3, pages 417-424.
Crossref

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