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DNA Dynamics and Chromosome Structure

The Second-Largest Subunit of the Mouse DNA Polymerase α-Primase Complex Facilitates Both Production and Nuclear Translocation of the Catalytic Subunit of DNA Polymerase α

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Pages 3552-3562 | Received 23 Jun 1997, Accepted 02 Mar 1998, Published online: 28 Mar 2023

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Robert D. Ott, Christoph Rehfuess, Vladimir N. Podust, Jill E. Clark & Ellen Fanning. (2002) Role of the p68 Subunit of Human DNA Polymerase α-Primase in Simian Virus 40 DNA Replication. Molecular and Cellular Biology 22:16, pages 5669-5678.
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Takeshi Mizuno, Kumiko Yamagishi, Hiroshi Miyazawa & Fumio Hanaoka. (1999) Molecular Architecture of the Mouse DNA Polymerase α-Primase Complex. Molecular and Cellular Biology 19:11, pages 7886-7896.
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Yinbo Zhang, Andrey G. Baranovskiy, Tahir H. Tahirov & Youri I. Pavlov. (2014) The C-terminal Domain of the DNA Polymerase Catalytic Subunit Regulates the Primase and Polymerase Activities of the Human DNA Polymerase α-Primase Complex. Journal of Biological Chemistry 289:32, pages 22021-22034.
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Bo Zhou, Diana R. Arnett, Xian Yu, Aaron Brewster, Gregory A. Sowd, Charlies L. Xie, Stefan Vila, Dahai Gai, Ellen Fanning & Xiaojiang S. Chen. (2012) Structural Basis for the Interaction of a Hexameric Replicative Helicase with the Regulatory Subunit of Human DNA Polymerase α-Primase. Journal of Biological Chemistry 287:32, pages 26854-26866.
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Christian S. Eichinger, Takeshi Mizuno, Keiko Mizuno, Yasuyuki Miyake, Ken-ichiro Yanagi, Naoko Imamoto & Fumio Hanaoka. (2009) Aberrant DNA Polymerase α Is Excluded from the Nucleus by Defective Import and Degradation in the Nucleus. Journal of Biological Chemistry 284:44, pages 30604-30614.
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Ruslan I. Dmitriev, Irina A. Okkelman, Roman A. Abdulin, Mikhail I. Shakhparonov & Nikolay B. Pestov. (2009) Nuclear transport of protein TTC4 depends on the cell cycle. Cell and Tissue Research 336:3, pages 521-527.
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Masaharu Takemura, Shonen Yoshida, Tetsu Akiyama, Masatoshi Kitagawa & Yoshiji Yamada. (2006) Role of the second-largest subunit of DNA polymerase α in the interaction between the catalytic subunit and hyperphosphorylated retinoblastoma protein in late S phase. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1764:9, pages 1447-1453.
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Robin M. Ricke & Anja-Katrin Bielinsky. (2006) A Conserved Hsp10-like Domain in Mcm10 Is Required to Stabilize the Catalytic Subunit of DNA Polymerase-α in Budding Yeast. Journal of Biological Chemistry 281:27, pages 18414-18425.
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Yasuyuki Miyake, Takeshi Mizuno, Ken-ichiro Yanagi & Fumio Hanaoka. (2005) Novel Splicing Variant of Mouse Orc1 Is Deficient in Nuclear Translocation and Resistant for Proteasome-mediated Degradation. Journal of Biological Chemistry 280:13, pages 12643-12652.
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Chikako Murakami, Takeshi Miuzno, Fumio Hanaoka, Hiromi Yoshida, Kengo Sakaguchi & Yoshiyuki Mizushina. (2004) Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG). Biochemical Pharmacology 67:7, pages 1373-1380.
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R.W.P Smith & H.-P Nasheuer. (2002) Control of complex formation of DNA polymerase α-primase and cell-free DNA replication by the C-terminal amino acids of the largest subunit p180. FEBS Letters 527:1-3, pages 143-146.
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Richard W.P. Smith, Claudia Steffen, Frank Grosse & Heinz-Peter Nasheuer. (2002) Species Specificity of Simian Virus 40 DNA Replication in Vitro Requires Multiple Functions of Human DNA Polymerase α. Journal of Biological Chemistry 277:23, pages 20541-20548.
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Masaharu Takemura. (2002) Evolution and degeneration of eukaryotic DNA replication system. Biosystems 65:2-3, pages 139-145.
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Oliver Schub, Gabor Rohaly, Richard W.P. Smith, Annerose Schneider, Silke Dehde, Irena Dornreiter & Heinz-Peter Nasheuer. (2001) Multiple Phosphorylation Sites of DNA Polymerase α-Primase Cooperate to Regulate the Initiation of DNA Replication in Vitro. Journal of Biological Chemistry 276:41, pages 38076-38083.
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Odilia Popanda, Claudia Flohr, Jia-Chun Dai, Andreas Hunzicker & Heinz Walter Thielmann. (2001) A mutation in subunit B of the DNA polymerase ?-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase ?-primase complex. Molecular Carcinogenesis 31:4, pages 171-183.
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Masashi Uchiyama, Dominic Griffiths, Ken-ichi Arai & Hisao Masai. (2001) Essential Role of Sna41/Cdc45 in Loading of DNA Polymerase α onto Minichromosome Maintenance Proteins in Fission Yeast. Journal of Biological Chemistry 276:28, pages 26189-26196.
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David N. FrickCharles C. Richardson. (2001) DNA Primases. Annual Review of Biochemistry 70:1, pages 39-80.
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Naoko S. Nishikawa, Masako Izumi, Masayuki Yokoi, Hiroshi Miyazawa & Fumio Hanaoka. (2001) E2F regulates growth-dependent transcription of genes encoding both catalytic and regulatory subunits of mouse primase. Genes to Cells 6:1, pages 57-70.
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Bahram Arezi & Robert D Kuchta. (2000) Eukaryotic DNA primase. Trends in Biochemical Sciences 25:11, pages 572-576.
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Masako Izumi, Masayuki Yokoi, Naoko S. Nishikawa, Hiroshi Miyazawa, Akio Sugino, Masahiro Yamagishi, Masamitsu Yamaguchi, Akio Matsukage, Fumio Yatagai & Fumio Hanaoka. (2000) Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase α is controlled by E2F, an Ets-related transcription factor, and Sp1. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1492:2-3, pages 341-352.
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Manuel Stucki, Igor Stagljar, Zophonias O. Jonsson & Ulrich Hübscher. 2000. 261 298 .
Iwao Kukimoto, Hiroshi Igaki & Tadahito Kanda. (1999) Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase α. European Journal of Biochemistry 265:3, pages 936-943.
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Kazufumi Kuroda & Ryu Ueda. (1999) Phosphorylation and Dephosphorylation of the B Subunit of DNA Polymerase α-Primase Complex in the Early Embryogenesis ofDrosophila. Biochemical and Biophysical Research Communications 254:2, pages 372-377.
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