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Molecular and Cellular Biology Volume 18, 1998 - Issue 9
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Transcriptional Regulation

Dual Roles for Pax-6: a Transcriptional Repressor of Lens Fiber Cell-Specific β-Crystallin Genes

Melinda K. Duncana Department of Biological Sciences, The University of Delaware, Newark, Delaware19716
,
John I. Haynes IIb Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, Maryland20892-2730
,
Ales Cveklb Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, Maryland20892-2730
&
Joram Piatigorskyb Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, Maryland20892-2730Correspondence[email protected]
Pages 5579-5586 | Received 20 Apr 1998, Accepted 22 May 1998, Published online: 28 Mar 2023

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Abby L. Manthey, Salil A. Lachke, Paul G. FitzGerald, Robert W. Mason, David A. Scheiblin, John H. McDonald & Melinda K. Duncan. (2014) Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mechanisms of Development 131, pages 86-110.
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Konstantinos Sousounis & Panagiotis A Tsonis. (2012) Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses. Human Genomics 6:1.
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Aurélie de Thonel, Anne Le Mouël & Valérie Mezger. (2012) Transcriptional regulation of small HSP—HSF1 and beyond. The International Journal of Biochemistry & Cell Biology 44:10, pages 1593-1612.
Crossref
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Daniel W. H. Ho, Maurice K. H. Yap, Po Wah Ng, Wai Yan Fung & Shea Ping Yip. (2012) Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus. PLoS ONE 7:6, pages e40238.
Crossref
Hajime Ogino, Haruki Ochi, Hasan Mahmud Reza & Kunio Yasuda. (2012) Transcription factors involved in lens development from the preplacodal ectoderm. Developmental Biology 363:2, pages 333-347.
Crossref
Yury Kiselev, Tonje Engevik Eriksen, Siri Forsdahl, Lan Huong Thi Nguyen & Ingvild Mikkola. (2012) 3T3 Cell Lines Stably Expressing Pax6 or Pax6(5a) – A New Tool Used for Identification of Common and Isoform Specific Target Genes. PLoS ONE 7:2, pages e31915.
Crossref
Yoshio Wakamatsu. (2011) Mutual repression between Pax3 and Pax6 is involved in the positioning of ophthalmic trigeminal placode in avian embryo. Development, Growth & Differentiation 53:9, pages 994-1003.
Crossref
Eun Sook Jang & James E. Goldman. (2011) Pax6 Expression Is Sufficient to Induce a Neurogenic Fate in Glial Progenitors of the Neonatal Subventricular Zone. PLoS ONE 6:6, pages e20894.
Crossref
Andrea Caceres, Fu Shang, Eric Wawrousek, Qing Liu, Orna Avidan, Ales Cvekl, Ying Yang, Aydin Haririnia, Andrew Storaska, David Fushman, Jer Kuszak, Edward Dudek, Donald Smith & Allen Taylor. (2010) Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo. PLoS ONE 5:10, pages e13331.
Crossref
Naoko Fujimura, Makoto M. Taketo, Mikiro Mori, Vladimir Korinek & Zbynek Kozmik. (2009) Spatial and temporal regulation of Wnt/β-catenin signaling is essential for development of the retinal pigment epithelium. Developmental Biology 334:1, pages 31-45.
Crossref
Bonnie M. Weasner, Brandon Weasner, Stephanie M. DeYoung, Scott D. Michaels & Justin P. Kumar. (2009) Transcriptional activities of the Pax6 gene eyeless regulate tissue specificity of ectopic eye formation in Drosophila. Developmental Biology 334:2, pages 492-502.
Crossref
Ohad ShahamApril N. SmithMichael L. RobinsonMakoto M. TaketoRichard A. LangRuth Ashery-Padan. (2009) Pax6 is essential for lens fiber cell differentiation. Development 136:15, pages 2567-2578.
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Refugio García-Villegas, Juan Escamilla, Erika Sánchez-Guzmán, Angela Pastén, Miriam Hernández-Quintero, Eber Gómez-Flores & Federico Castro-Muñozledo. (2009) Pax-6 is expressed early in the differentiation of a corneal epithelial model system. Journal of Cellular Physiology 220:2, pages 348-356.
Crossref
Amy N. Riesenberg, Tien T. Le, Minde I. Willardsen, David C. Blackburn, Monica L. Vetter & Nadean L. Brown. (2009) Pax6 regulation of Math5 during mouse retinal neurogenesis . genesis 47:3, pages 175-187.
Crossref
Minde I. Willardsen, Arminda Suli, Yi Pan, Nicholas Marsh-Armstrong, Chi-Bin Chien, Heithem El-Hodiri, Nadean L. Brown, Kathryn B. Moore & Monica L. Vetter. (2009) Temporal regulation of Ath5 gene expression during eye development. Developmental Biology 326:2, pages 471-481.
Crossref
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Crossref
Hsin-Yi Ho, Kuo-Hsuan Chang, Jennifer Nichols & Meng Li. (2009) Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells. Mechanisms of Development 126:1-2, pages 18-29.
Crossref
F David Carmona, Rafael Jiménez & J Martin Collinson. (2008) The molecular basis of defective lens development in the Iberian mole. BMC Biology 6:1.
Crossref
Kristyna Jonasova & Zbynek Kozmik. (2008) Eye evolution: Lens and cornea as an upgrade of animal visual system. Seminars in Cell & Developmental Biology 19:2, pages 71-81.
Crossref
J. Fielding Hejtmancik & Joram Piatigorsky. 2008. Albert &amp Jakobiec's Principles &amp Practice of Ophthalmology. Albert &amp Jakobiec's Principles &amp Practice of Ophthalmology 1341 1364 .
Ales Cvekl & Melinda K. Duncan. (2007) Genetic and epigenetic mechanisms of gene regulation during lens development. Progress in Retinal and Eye Research 26:6, pages 555-597.
Crossref
Jörn Lakowski, Anirban Majumder & James D. Lauderdale. (2007) Mechanisms controlling Pax6 isoform expression in the retina have been conserved between teleosts and mammals. Developmental Biology 307:2, pages 498-520.
Crossref
Vladimir N. Simirskii, Yan Wang & Melinda K. Duncan. (2007) Conditional deletion of β1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Developmental Biology 306:2, pages 658-668.
Crossref
Qin Yan, Wen-Bin Liu, Jichao Qin, Jinping Liu, He-Ge Chen, Xiaoqin Huang, Lili Chen, Shuming Sun, Mi Deng, Lili Gong, Yong Li, Lan Zhang, Yan Liu, Hao Feng, Yamei Xiao, Yun Liu & David W.-C. Li. (2007) Protein Phosphatase-1 Modulates the Function of Pax-6, a Transcription Factor Controlling Brain and Eye Development. Journal of Biological Chemistry 282:19, pages 13954-13965.
Crossref
Julie C. Kiefer, Pliny A. Smith & Susan E. Mango. (2007) PHA-4/FoxA cooperates with TAM-1/TRIM to regulate cell fate restriction in the C. elegans foregut. Developmental Biology 303:2, pages 611-624.
Crossref
Pontus C. Holm, Michael T. Mader, Nicole Haubst, Andrea Wizenmann, Mikael Sigvardsson & Magdalena Götz. (2007) Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon. Molecular and Cellular Neuroscience 34:1, pages 99-119.
Crossref
Eun A. Kim, Yoon Tae Noh, Myung-Jeom Ryu, Hyun-Taek Kim, Sung-Eun Lee, Cheol-Hee Kim, Cheolju Lee, Young Ho Kim & Cheol Yong Choi. (2006) Phosphorylation and Transactivation of Pax6 by Homeodomain-interacting Protein Kinase 2. Journal of Biological Chemistry 281:11, pages 7489-7497.
Crossref
Meryl Castellini, Louise V Wolf, Bharesh K Chauhan, Deni S Galileo, Manfred W Kilimann, Ales Cvekl & Melinda K Duncan. (2005) Palm is expressed in both developing and adult mouse lens and retina. BMC Ophthalmology 5:1.
Crossref
Yoko Arai, Nobuo Funatsu, Keiko Numayama-Tsuruta, Tadashi Nomura, Shun Nakamura & Noriko Osumi. (2005) Role of Fabp7 , a Downstream Gene of Pax6, in the Maintenance of Neuroepithelial Cells during Early Embryonic Development of the Rat Cortex . The Journal of Neuroscience 25:42, pages 9752-9761.
Crossref
Ying Yang & Ales Cvekl. (2005) Tissue-specific Regulation of the Mouse αA-crystallin Gene in Lens via Recruitment of Pax6 and c-Maf to its Promoter. Journal of Molecular Biology 351:3, pages 453-469.
Crossref
Jih-Guang Yao & Y Henry Sun. (2005) Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development. The EMBO Journal 24:14, pages 2602-2612.
Crossref
Nicole Haubst, Joachim Berger, Venugopal Radjendirane, Jochen Graw, Jack Favor, Grady F. Saunders, Anastassia Stoykova & Magdalena Götz. (2004) Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development. Development 131:24, pages 6131-6140.
Crossref
Ying Yang, Bharesh K. Chauhan, Kveta Cveklova & Ales Cvekl. (2004) Transcriptional Regulation of Mouse αB- and γF-Crystallin Genes in Lens: Opposite Promoter-specific Interactions Between Pax6 and Large Maf Transcription Factors. Journal of Molecular Biology 344:2, pages 351-368.
Crossref
. 2010. Development of the Ocular Lens. Development of the Ocular Lens.
Derek Spieler, Nicole Bäumer, Jürg Stebler, Marion Köprunner, Michal Reichman-Fried, Ulrike Teichmann, Erez Raz, Michael Kessel & Lars Wittler. (2004) Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1. Developmental Biology 269:2, pages 567-579.
Crossref
Wenwu Cui, Stanislav I. Tomarev, Joram Piatigorsky, Ana B. Chepelinsky & Melinda K. Duncan. (2004) Mafs, Prox1, and Pax6 Can Regulate Chicken βB1-Crystallin Gene Expression. Journal of Biological Chemistry 279:12, pages 11088-11095.
Crossref
Isabel M Hanson. (2003) PAX6 and Congenital Eye Malformations. Pediatric Research 54:6, pages 791-796.
Crossref
Janine Davis, Melinda K. Duncan, W. Gerald RobisonJrJr & Joram Piatigorsky. (2003) Requirement for Pax6 in corneal morphogenesis: a role in adhesion. Journal of Cell Science 116:11, pages 2157-2167.
Crossref
Claire R. Weston, Anthony Wong, J. Perry Hall, Mary E.P. Goad, Richard A. Flavell & Roger J. Davis. (2003) JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes & Development 17:10, pages 1271-1280.
Crossref
Haruki Ochi, Hajime Ogino, Yuji Kageyama & Kunio Yasuda. (2003) The Stability of the Lens-specific Maf Protein is Regulated by Fibroblast Growth Factor (FGF)/ERK Signaling in Lens Fiber Differentiation. Journal of Biological Chemistry 278:1, pages 537-544.
Crossref
Hao Wu, Eric J. Lien, Linda L. Lien, Richard M. Schultz, Vishnu Ji Ram, Esteban Domingo, Paul Spence, Satya P. Gupta, Suraj P. Bhat & Elcira C. VillarrealSuraj P. Bhat. 2003. Progress in Drug Research. Progress in Drug Research 205 262 .
Bharesh K. Chauhan, Nathan A. Reed, Ying Yang, Lukáš Čermák, Lixing Reneker, Melinda K. Duncan & Aleš Cvekl. (2002) A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens. Genes to Cells 7:12, pages 1267-1283.
Crossref
T. Ian Simpson & David J. Price. (2002) Pax6; A pleiotropic player in development. BioEssays 24:11, pages 1041-1051.
Crossref
Daniela C Baulmann, Andreas Ohlmann, Cassandra Flügel-Koch, Sumanta Goswami, Ales Cvekl & Ernst R Tamm. (2002) Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mechanisms of Development 118:1-2, pages 3-17.
Crossref
Mayumi Muta, Yusuke Kamachi, Aki Yoshimoto, Yujiro Higashi & Hisato Kondoh. (2002) Distinct roles of SOX2, Pax6 and Maf transcription factors in the regulation of lens-specific δ 1-crystallin enhancer . Genes to Cells 7:8, pages 791-805.
Crossref
Joram Piatigorsky. (2002) Enigma of the Abundant Water-Soluble Cytoplasmic Proteins of the Cornea. Cornea 21, pages S7-S12.
Crossref
Bharesh K. Chauhan, Nathan A. Reed, Weijia Zhang, Melinda K. Duncan, Manfred W. Kilimann & Aleš Cvekl. (2002) Identification of Genes Downstream of Pax6 in the Mouse Lens Using cDNA Microarrays. Journal of Biological Chemistry 277:13, pages 11539-11548.
Crossref
Jarmila Králová, Thomas Czerny, Hana Španielová, Veronika Ratajová & Zbynek Kozmik. (2002) Complex regulatory element within the γE- and γF-crystallin enhancers mediates Pax6 regulation and is required for induction by retinoic acid. Gene 286:2, pages 271-282.
Crossref
Eleonora Carosa, Zbynek Kozmik, J. Edward Rall & Joram Piatigorsky. (2002) Structure and Expression of the Scallop Ω-Crystallin Gene. Journal of Biological Chemistry 277:1, pages 656-664.
Crossref
Hisato Kondoh. 2002. Mouse Development. Mouse Development 519 538 .
Tony Lefebvre, Nathalie Planque, Denis Leleu, Manuella Bailly, Marie-Laure Caillet-Boudin, Simon Saule & Jean-Claude Michalski. (2002) O -glycosylation of the nuclear forms of Pax-6 products in quail neuroretina cells . Journal of Cellular Biochemistry 85:1, pages 208-218.
Crossref
Robert L. ChowRichard A. Lang. (2001) Early Eye Development in Vertebrates. Annual Review of Cell and Developmental Biology 17:1, pages 255-296.
Crossref
Joram Piatigorsky. (2001) Enigma of the Abundant Water-Soluble Cytoplasmic Proteins of the Cornea. Cornea 20:8, pages 853-858.
Crossref
Wei V. Chen, J. Fielding Hejtmancik, Joram Piatigorsky & Melinda K. Duncan. (2001) The mouse βB1-crystallin promoter: strict regulation of lens fiber cell specificity. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1519:1-2, pages 30-38.
Crossref
Hisato Kondoh. 2001. eLS. eLS.
Ingvild Mikkola, Jack-Ansgar Bruun, Turid Holm & Terje Johansen. (2001) Superactivation of Pax6-mediated Transactivation from Paired Domain-binding Sites by DNA-independent Recruitment of Different Homeodomain Proteins. Journal of Biological Chemistry 276:6, pages 4109-4118.
Crossref
Kohsuke Kataoka, Kiyomi Yoshitomo-Nakagawa, Setsuko Shioda & Makoto Nishizawa. (2001) A Set of Hox Proteins Interact with the Maf Oncoprotein to Inhibit Its DNA Binding, Transactivation, and Transforming Activities. Journal of Biological Chemistry 276:1, pages 819-826.
Crossref
M.K. Duncan, Z. Kozmik, K. Cveklova, J. Piatigorsky & A. Cvekl. (2000) Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. Journal of Cell Science 113:18, pages 3173-3185.
Crossref
Eiji Matsunaga, Isato Araki & Harukazu Nakamura. (2000) Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2 . Development 127:11, pages 2357-2365.
Crossref
Jeremy M. Sivak, Royce Mohan, William B. Rinehart, Pin-Xian Xu, Richard L. Maas & M. Elizabeth Fini. (2000) Pax-6 expression and activity are induced in the reepithelializing cornea and control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B. Developmental Biology 222:1, pages 41-54.
Crossref
YI WEN, GEORGE SACHS & CHRISTOPH ATHMANN. (2000) A Novel Lens Epithelium Gene, LEP503, is Highly Conserved in Different Vertebrate Species and is Developmentally Regulated in Postnatal Rat Lens. Experimental Eye Research 70:2, pages 159-168.
Crossref
Brian Z. Ring, Sabine P. Cordes, Paul A. Overbeek & Gregory S. Barsh. (2000) Regulation of mouse lens fiber cell development and differentiation by the Maf gene . Development 127:2, pages 307-317.
Crossref
Nicolas Hirsch & Robert M. Grainger. 2000. Vertebrate Eye Development. Vertebrate Eye Development 51 68 .
Hisato Kondoh. (1999) Transcription factors for lens development assessed in vivo. Current Opinion in Genetics & Development 9:3, pages 301-308.
Crossref
Peter J Francis, Vanita Berry, Anthony T Moore & Shomi Bhattacharya. (1999) Lens biology: development and human cataractogenesis. Trends in Genetics 15:5, pages 191-196.
Crossref
James I. Kim, Tiansen Li, I.-Cheng Ho, Michael J. Grusby & Laurie H. Glimcher. (1999) Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proceedings of the National Academy of Sciences 96:7, pages 3781-3785.
Crossref

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