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Transcriptional Regulation

Interactions between the Class II Transactivator and CREB Binding Protein Increase Transcription of Major Histocompatibility Complex Class II Genes

Joseph D. FontesHoward Hughes Medical Institute, Departments of Medicine, Immunology, and Microbiology, University of California San Francisco, San Francisco, California94143-0703
,
Satoshi KanazawaHoward Hughes Medical Institute, Departments of Medicine, Immunology, and Microbiology, University of California San Francisco, San Francisco, California94143-0703
,
Dickson JeanHoward Hughes Medical Institute, Departments of Medicine, Immunology, and Microbiology, University of California San Francisco, San Francisco, California94143-0703
&
B. Matija PeterlinHoward Hughes Medical Institute, Departments of Medicine, Immunology, and Microbiology, University of California San Francisco, San Francisco, California94143-0703Correspondence[email protected]
Pages 941-947 | Received 10 Jun 1998, Accepted 14 Oct 1998, Published online: 28 Mar 2023

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Priya Londhe & Judith K. Davie. (2011) Gamma Interferon Modulates Myogenesis through the Major Histocompatibility Complex Class II Transactivator, CIITA. Molecular and Cellular Biology 31:14, pages 2854-2866.
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Olivia I. Koues, R. Kyle Dudley, Agnieszka D. Truax, Dawson Gerhardt, Kavita P. Bhat, Sam McNeal & Susanna F. Greer. (2008) Regulation of Acetylation at the Major Histocompatibility Complex Class II Proximal Promoter by the 19S Proteasomal ATPase Sug1. Molecular and Cellular Biology 28:19, pages 5837-5850.
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Eleni Zika, Susanna F. Greer, Xin-Sheng Zhu & Jenny P.-Y. Ting. (2003) Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation. Molecular and Cellular Biology 23:9, pages 3091-3102.
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Rajini Mudhasani & Joseph D. Fontes. (2002) The Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes. Molecular and Cellular Biology 22:14, pages 5019-5026.
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Ann C. Morris, Guy W. Beresford, Myesha R. Mooney & Jeremy M. Boss. (2002) Kinetics of a Gamma Interferon Response: Expression and Assembly of CIITA Promoter IV and Inhibition by Methylation. Molecular and Cellular Biology 22:13, pages 4781-4791.
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Xin-Sheng Zhu & Jenny P.-Y. Ting. (2001) A 36-Amino-Acid Region of CIITA Is an Effective Inhibitor of CBP: Novel Mechanism of Gamma Interferon-Mediated Suppression of Collagen α2(I) and Other Promoters. Molecular and Cellular Biology 21:20, pages 7078-7088.
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Tyler J. Sisk, Stacey Roys & Cheong-Hee Chang. (2001) Self-Association of CIITA and Its Transactivation Potential. Molecular and Cellular Biology 21:15, pages 4919-4928.
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Guoxuan Li, Jonathan A. Harton, Xinsheng Zhu & Jenny P.-Y. Ting. (2001) Downregulation of CIITA Function by Protein Kinase A (PKA)-Mediated Phosphorylation: Mechanism of Prostaglandin E, Cyclic AMP, and PKA Inhibition of Class II Major Histocompatibility Complex Expression in Monocytic Lines. Molecular and Cellular Biology 21:14, pages 4626-4635.
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Michael W. Linhoff, Jonathan A. Harton, Drew E. Cressman, Brian K. Martin & Jenny Pan-Yun Ting. (2001) Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains. Molecular and Cellular Biology 21:9, pages 3001-3011.
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Charalambos Spilianakis, Joseph Papamatheakis & Androniki Kretsovali. (2000) Acetylation by PCAF Enhances CIITA Nuclear Accumulation and Transactivation of Major Histocompatibility Complex Class II Genes. Molecular and Cellular Biology 20:22, pages 8489-8498.
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Jonathan A. Harton & Jenny P.-Y. Ting. (2000) Class II Transactivator: Mastering the Art of Major Histocompatibility Complex Expression. Molecular and Cellular Biology 20:17, pages 6185-6194.
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Xin-Sheng Zhu, Michael W. Linhoff, Guoxuan Li, Keh-Chuang Chin, Sankar N. Maity & Jenny Pan-Yun Ting. (2000) Transcriptional Scaffold: CIITA Interacts with NF-Y, RFX, and CREB To Cause Stereospecific Regulation of the Class II Major Histocompatibility Complex Promoter. Molecular and Cellular Biology 20:16, pages 6051-6061.
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Debra J. Taxman, Drew E. Cressman & Jenny P.-Y. Ting. (2000) Identification of Class II Transcriptional Activator-Induced Genes by Representational Difference Analysis: Discoordinate Regulation of the DNα/DOβ Heterodimer. The Journal of Immunology 165:3, pages 1410-1416.
Crossref
Saara Aittomäki, Marko Pesu, Bernd Groner, Olli A. Jänne, Jorma J. Palvimo & Olli Silvennoinen. (2000) Cooperation Among Stat1, Glucocorticoid Receptor, and PU.1 in Transcriptional Activation of the High-Affinity Fcγ Receptor I in Monocytes. The Journal of Immunology 164:11, pages 5689-5697.
Crossref
Krzysztof Masternak, Annick Muhlethaler-Mottet, Jean Villard, Madeleine Zufferey, Viktor Steimle & Walter Reith. (2000) CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex. Genes & Development 14:9, pages 1156-1166.
Crossref
Mohammed Saifuddin, Kenneth A. Roebuck, Cheong-hee Chang, Jenny P. Y. Ting & Gregory T. Spear. (2000) Cutting Edge: Activation of HIV-1 Transcription by the MHC Class II Transactivator. The Journal of Immunology 164:8, pages 3941-3945.
Crossref
Uma M. Nagarajan, Ad Peijnenburg, Sam J. P. Gobin, Jeremy M. Boss & Peter J. van den Elsen. (2000) Novel Mutations Within the RFX-B Gene and Partial Rescue of MHC and Related Genes Through Exogenous Class II Transactivator in RFX-B-Deficient Cells. The Journal of Immunology 164:7, pages 3666-3674.
Crossref
François-Michel Boisvert, Michael J. Hendzel & David P. Bazett-Jones. (2000) Promyelocytic Leukemia (Pml) Nuclear Bodies Are Protein Structures That Do Not Accumulate RNA. Journal of Cell Biology 148:2, pages 283-292.
Crossref
Satoshi Kanazawa, Takashi Okamoto & B.Matija Peterlin. (2000) Tat Competes with CIITA for the Binding to P-TEFb and Blocks the Expression of MHC Class II Genes in HIV Infection. Immunity 12:1, pages 61-70.
Crossref
Jeffrey C Webster & John A Cidlowski. (1999) Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression. Trends in Endocrinology & Metabolism 10:10, pages 396-402.
Crossref
Walter Reith, Annick Muhlethaler-Mottet, Krzysztof Masternak, Jean Villard & Bernard Mach. (1999) The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression. Microbes and Infection 1:11, pages 839-846.
Crossref
Jenny Pan-Yun Ting & Xin-Sheng Zhu. (1999) Class II MHC genes: a model gene regulatory system with great biologic consequences. Microbes and Infection 1:11, pages 855-861.
Crossref
Joseph D Fontes, Satoshi Kanazawa, Nada Nekrep & B.Matija Peterlin. (1999) The class II transactivator CIITA is a transcriptional integrator. Microbes and Infection 1:11, pages 863-869.
Crossref
Jonathan A. HartonDrew E. CressmanKeh-Chuang Chin, Channing J. DerJenny P. -Y. Ting. (1999) GTP Binding by Class II Transactivator: Role in Nuclear Import. Science 285:5432, pages 1402-1405.
Crossref
Angela DeSandro, Uma M. Nagarajan & Jeremy M. Boss. (1999) The Bare Lymphocyte Syndrome: Molecular Clues to the Transcriptional Regulation of Major Histocompatibility Complex Class II Genes. The American Journal of Human Genetics 65:2, pages 279-286.
Crossref
Carlos S Moreno, Guy W Beresford, Pascale Louis-Plence, Ann C Morris & Jeremy M Boss. (1999) CREB Regulates MHC Class II Expression in a CIITA-Dependent Manner. Immunity 10:2, pages 143-151.
Crossref

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