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Molecular and Cellular Biology Volume 19, 1999 - Issue 11
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Transcriptional Regulation

An ATP/ADP-Dependent Molecular Switch Regulates the Stability of p53-DNA Complexes

Andrei L. OkorokovYCR P53 Research Group, Department of Biology, University of York, York, YO10 5DD, United Kingdom
&
Jo MilnerYCR P53 Research Group, Department of Biology, University of York, York, YO10 5DD, United KingdomCorrespondence[email protected]
Pages 7501-7510 | Received 14 May 1999, Accepted 27 Jul 1999, Published online: 28 Mar 2023

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Kevin G. McLure, Masatoshi Takagi & Michael B. Kastan. (2004) NAD+ Modulates p53 DNA Binding Specificity and Function. Molecular and Cellular Biology 24:22, pages 9958-9967.
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Articles from other publishers (30)

Yanqing Liu & Wei Gu. (2022) The complexity of p53-mediated metabolic regulation in tumor suppression. Seminars in Cancer Biology 85, pages 4-32.
Crossref
James Kealey, Heiko Düssmann, Irene Llorente-Folch, Natalia Niewidok, Manuela Salvucci, Jochen H. M. Prehn & Beatrice D’Orsi. (2022) Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study. Frontiers in Cell and Developmental Biology 10.
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Shi Zhou, Yi Xing, Xing Yuan, Guanlan Wu, Xiaolin Zhu & Dongmei Wu. (2021) Cytotoxicity and action mechanisms of polycyclic aromatic hydrocarbons by a miniature electrochemical detection system. Biomedical Microdevices 23:2.
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Timothy J. Humpton & Karen H. Vousden. (2016) Regulation of Cellular Metabolism and Hypoxia by p53. Cold Spring Harbor Perspectives in Medicine 6:7, pages a026146.
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Yuji Itoh, Agato Murata, Seiji Sakamoto, Kei Nanatani, Takehiko Wada, Satoshi Takahashi & Kiyoto Kamagata. (2016) Activation of p53 Facilitates the Target Search in DNA by Enhancing the Target Recognition Probability. Journal of Molecular Biology 428:14, pages 2916-2930.
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Doriane Lorendeau, Stefan Christen, Gianmarco Rinaldi & Sarah-Maria Fendt. (2015) Metabolic control of signalling pathways and metabolic auto-regulation. Biology of the Cell 107:8, pages 251-272.
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Pearl Lee, Karen H Vousden & Eric C Cheung. (2014) TIGAR, TIGAR, burning bright. Cancer & Metabolism 2:1.
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Nicola Pacini & Fabio Borziani. (2014) Cancer Stem Cell Theory and the Warburg Effect, Two Sides of the Same Coin?. International Journal of Molecular Sciences 15:5, pages 8893-8930.
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Shalini Verma & Basuthkar J. Rao. (2014) Uncovering the Basis of ATP Hydrolysis Activity in Purified Human p53 Protein: A Reinvestigation. PLoS ONE 9:4, pages e93652.
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Andrew M. Cobb, Brian R. Jackson, Ella Kim, Philip L. Bond & Richard P. Bowater. (2013) Sequence-specific and DNA structure-dependent interactions of Escherichia coli MutS and human p53 with DNA. Analytical Biochemistry 442:1, pages 51-61.
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Caroline JoseSu MelserGiovanni BenardRodrigue Rossignol. (2013) Mitoplasticity: Adaptation Biology of the Mitochondrion to the Cellular Redox State in Physiology and Carcinogenesis. Antioxidants & Redox Signaling 18:7, pages 808-849.
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Jing Zhang, Kyle K. Biggar & Kenneth B. Storey. (2013) Regulation of p53 by reversible post-transcriptional and post-translational mechanisms in liver and skeletal muscle of an anoxia tolerant turtle, Trachemys scripta elegans. Gene 513:1, pages 147-155.
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Jigneshkumar Patel, Ravi R Pathak & Shiraz Mujtaba. (2011) The biology of lysine acetylation integrates transcriptional programming and metabolism. Nutrition & Metabolism 8:1.
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Shannon Compton, Chul Kim, Nicholas B. Griner, Prasanth Potluri, Immo E. Scheffler, Sabyasachi Sen, D. Joseph Jerry, Sallie Schneider & Nagendra Yadava. (2011) Mitochondrial Dysfunction Impairs Tumor Suppressor p53 Expression/Function. Journal of Biological Chemistry 286:23, pages 20297-20312.
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A. O. Zheltukhin & P. M. Chumakov. (2011) Constitutive and induced functions of the p53 gene. Biochemistry (Moscow) 75:13, pages 1692-1721.
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Ayeda Ayed & Theodore HuppVladana Vukojevic, Tatiana Yakovleva & Georgy Bakalkin. 2010. p53. p53 127 141 .
Karen H. Vousden & Kevin M. Ryan. (2009) p53 and metabolism. Nature Reviews Cancer 9:10, pages 691-700.
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Ivan A. Olovnikov, Julia E. Kravchenko & Peter M. Chumakov. (2009) Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense. Seminars in Cancer Biology 19:1, pages 32-41.
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Chad A. Corcoran, Ying Huang & M. Saeed Sheikh. 2009. Mitochondria and Cancer. Mitochondria and Cancer 131 150 .
P. M. Chumakov. (2007) Versatile functions of p53 protein in multicellular organisms. Biochemistry (Moscow) 72:13, pages 1399-1421.
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Andrei L Okorokov, Michael B Sherman, Celia Plisson, Vera Grinkevich, Kristmundur Sigmundsson, Galina Selivanova, Jo Milner & Elena V Orlova. (2006) The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity. The EMBO Journal 25:21, pages 5191-5200.
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O Laptenko & C Prives. (2006) Transcriptional regulation by p53: one protein, many possibilities. Cell Death & Differentiation 13:6, pages 951-961.
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Aditi Chatterjee, Elizabeth Mambo, Motonobu Osada, Sunil Upadhyay & David Sidransky. (2005) The effect of p53‐RNAi and p53 knockout on human 8‐oxoguanine DNA glycosylase (hOgg1) activity. The FASEB Journal 20:1, pages 112-114.
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Vladana Vukojević, Tatiana Yakovleva, Lars Terenius, Aladdin Pramanik & Georgy Bakalkin. (2004) Denaturation of dsDNA by p53: fluorescence correlation spectroscopy study. Biochemical and Biophysical Research Communications 316:4, pages 1150-1155.
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Torsten Stein, Diane Crighton, Lorna J Warnock, Jo Milner & Robert J White. (2002) Several regions of p53 are involved in repression of RNA polymerase III transcription. Oncogene 21:36, pages 5540-5547.
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Young R Seo, Melissa L Fishel, Sally Amundson, Mark R Kelley & Martin L Smith. (2002) Implication of p53 in base excision DNA repair: in vivo evidence. Oncogene 21:5, pages 731-737.
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Andrei L Okorokov, Carlos P Rubbi, Su Metcalfe & Jo Milner. (2002) The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage. Oncogene 21:3, pages 356-367.
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Negusse Habtemichael & Gyula Kovacs. (2002) Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells. Gene 283:1-2, pages 271-275.
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Tatiana Yakovleva, Aladdin Pramanik, Takashi Kawasaki, Koichi Tan-No, Irina Gileva, Heléne Lindegren, Ülo Langel, Tomas J. Ekström, Rudolf Rigler, Lars Terenius & Georgy Bakalkin. (2001) p53 Latency. Journal of Biological Chemistry 276:19, pages 15650-15658.
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Natalya Degtyareva, Deepa Subramanian & Jack D. Griffith. (2001) Analysis of the Binding of p53 to DNAs Containing Mismatched and Bulged Bases. Journal of Biological Chemistry 276:12, pages 8778-8784.
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