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Molecular and Cellular Biology Volume 19, 1999 - Issue 11
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Cell Growth and Development

Dual Lipid Modification of the Yeast Gγ Subunit Ste18p Determines Membrane Localization of Gβγ

Jodi E. HirschmanDepartment of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts01655-0122
&
Duane D. JennessDepartment of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts01655-0122Correspondence[email protected]
Pages 7705-7711 | Received 26 Apr 1999, Accepted 22 Jul 1999, Published online: 28 Mar 2023

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Christopher G. Alvaro, Allyson F. O'Donnell, Derek C. Prosser, Andrew A. Augustine, Aaron Goldman, Jeffrey L. Brodsky, Martha S. Cyert, Beverly Wendland & Jeremy Thorner. (2014) Specific α-Arrestins Negatively Regulate Pheromone Response by Down-Modulating the G-Protein-Coupled Receptor Ste2. Molecular and Cellular Biology 34:14, pages 2660-2681.
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Lindsay S. Garrenton, Andreas Braunwarth, Stefan Irniger, Ed Hurt, Markus Künzler & Jeremy Thorner. (2009) Nucleus-Specific and Cell Cycle-Regulated Degradation of Mitogen-Activated Protein Kinase Scaffold Protein Ste5 Contributes to the Control of Signaling Competence. Molecular and Cellular Biology 29:2, pages 582-601.
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Vaithish Velazhahan, Ning Ma, Gáspár Pándy-Szekeres, Albert J. Kooistra, Yang Lee, David E. Gloriam, Nagarajan Vaidehi & Christopher G. Tate. (2020) Structure of the class D GPCR Ste2 dimer coupled to two G proteins. Nature 589:7840, pages 148-153.
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Araceli Vázquez-Ibarra, Griselda Rodríguez-Martínez, Gehenna Guerrero-Serrano, Laura Kawasaki, Laura Ongay-Larios & Roberto Coria. (2020) Negative feedback-loop mechanisms regulating HOG- and pheromone-MAPK signaling in yeast. Current Genetics 66:5, pages 867-880.
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Tatiana A. Chernova, Zhen Yang, Tatiana S. Karpova, John R. Shanks, Natalia Shcherbik, Keith D. Wilkinson & Yury O. Chernoff. (2020) Aggregation and Prion-Inducing Properties of the G-Protein Gamma Subunit Ste18 are Regulated by Membrane Association. International Journal of Molecular Sciences 21:14, pages 5038.
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Henrik G. Dohlman & Sharon L. Campbell. (2019) Regulation of large and small G proteins by ubiquitination. Journal of Biological Chemistry 294:49, pages 18613-18623.
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Thamarai K. Janganan, Gongyou Chen, Daliang Chen, João F. Menino, Fernando Rodrigues, Maria I. Borges-Walmsley & Adrian R. Walmsley. (2015) A Gβ protein and the TupA Co-Regulator Bind to Protein Kinase A Tpk2 to Act as Antagonistic Molecular Switches of Fungal Morphological Changes. PLOS ONE 10:9, pages e0136866.
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Hui Lu, Yuan Sun, Yuan-Ying Jiang & Malcolm Whiteway. (2014) Ste18p Is a Positive Control Element in the Mating Process of Candida albicans. Eukaryotic Cell 13:4, pages 461-469.
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Piers A. Hemsley & Claire S. Grierson. (2011) The Ankyrin Repeats and DHHC S-acyl Transferase Domain of AKR1 Act Independently to Regulate Switching from Vegetative to Mating States in Yeast. PLoS ONE 6:12, pages e28799.
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Fenju Lai, Rentian Wu, Jiafeng Wang, Chunming Li, Lan Zou, Yongjun Lu & Chun Liang. (2011) Far3p domains involved in the interactions of Far proteins and pheromone-induced cell cycle arrest in budding yeast. FEMS Yeast Research 11:1, pages 72-79.
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Jun Ishii, Nobuo Fukuda, Tsutomu Tanaka, Chiaki Ogino & Akihiko Kondo. (2010) Protein-protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling. FEBS Journal 277:9, pages 1982-1995.
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Timothy Mulligan, Heiko Blaser, Erez Raz & Steven A. Farber. (2010) Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish. Cellular Signalling 22:2, pages 221-233.
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Qin Zeng, Xuejun Wang & Mark P. Running. (2007) Dual Lipid Modification of Arabidopsis G γ -Subunits Is Required for Efficient Plasma Membrane Targeting . Plant Physiology 143:3, pages 1119-1131.
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Janna E. Slessareva, Sheri M. Routt, Brenda Temple, Vytas A. Bankaitis & Henrik G. Dohlman. (2006) Activation of the Phosphatidylinositol 3-Kinase Vps34 by a G Protein α Subunit at the Endosome. Cell 126:1, pages 191-203.
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