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Molecular and Cellular Biology Volume 19, 1999 - Issue 12
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Transcriptional Regulation

Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development

Stuart B. Smith1 Hormone Research Institute
,
Hooi C. Ee1 Hormone Research Institute
,
Jennifer R. Conners1 Hormone Research Institute
&
Michael S. German1 Hormone Research Institute;2 Department of Medicine, University of California, San Francisco, San Francisco, California94143-0534Correspondence[email protected]
Pages 8272-8280 | Received 25 Mar 1999, Accepted 16 Aug 1999, Published online: 28 Mar 2023

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Reshmi Dassaye, Strini Naidoo & Marlon E. Cerf. (2016) Transcription factor regulation of pancreatic organogenesis, differentiation and maturation. Islets 8:1, pages 13-34.
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Blair K Gage, Robert K Baker & Timothy J Kieffer. (2014) Overexpression of PAX4 reduces glucagon expression in differentiating hESCs. Islets 6:2.
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Takeshi Miyatsuka, Taka-aki Matsuoka & Hideaki Kaneto. (2008) Transcription factors as therapeutic targets for diabetes. Expert Opinion on Therapeutic Targets 12:11, pages 1431-1442.
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Victoria Frost, Timothy Grocott, Michael R. Eccles & Andrew Chantry. (2008) Self-Regulated Pax Gene Expression and Modulation by the TGFβ Superfamily. Critical Reviews in Biochemistry and Molecular Biology 43:6, pages 371-391.
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Susan E. Samaras, Michelle A. Cissell, Kevin Gerrish, Christopher V. E. Wright, Maureen Gannon & Roland Stein. (2002) Conserved Sequences in a Tissue-Specific Regulatory Region of the pdx-1 Gene Mediate Transcription in Pancreatic β Cells: Role for Hepatocyte Nuclear Factor 3β and Pax6. Molecular and Cellular Biology 22:13, pages 4702-4713.
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Yoshio Fujitani, Yoshitaka Kajimoto, Tetsuyuki Yasuda, Taka-Aki Matsuoka, Hideaki Kaneto, Yutaka Umayahara, Noriko Fujita, Hirotaka Watada, Jun-Ichi Miyazaki, Yoshimitsu Yamasaki & Masatsugu Hori. (1999) Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas. Molecular and Cellular Biology 19:12, pages 8281-8291.
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