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Gene Expression

5-Azacytidine Induces Transgene Silencing by DNA Methylation in Chinese Hamster Cells

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Pages 3198-3204 | Received 13 Jul 1998, Accepted 07 Jan 1999, Published online: 28 Mar 2023

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Phillip A. Yates, Robert Burman, James Simpson, Olga N. Ponomoreva, Mathew J. Thayer & Mitchell S. Turker. (2003) Silencing of Mouse Aprt Is a Gradual Process in Differentiated Cells. Molecular and Cellular Biology 23:13, pages 4461-4470.
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Shivakumar Subbanna, Nagaraja N. Nagre, Madhu Shivakumar & Balapal S. Basavarajappa. (2016) A single day of 5-azacytidine exposure during development induces neurodegeneration in neonatal mice and neurobehavioral deficits in adult mice. Physiology & Behavior 167, pages 16-27.
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Sebastian Alvarado, Joanne Wyglinski, Matthew Suderman, Stephen A. Andrews & Moshe Szyf. (2013) Methylated DNA Binding Domain Protein 2 (MBD2) Coordinately Silences Gene Expression through Activation of the MicroRNA hsa-mir-496 Promoter in Breast Cancer Cell Line. PLoS ONE 8:10, pages e74009.
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F.Y. Zhao, C.P. Shao, Y. Li, W.Y. Ma, N. Tian & J.H. Zheng. (2013) 5-Azacytidine induces early stage apoptosis and promotes in vitro maturation by changing chromosomal construction in murine oocytes. Reproductive Toxicology 37, pages 56-61.
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Maria Maguire, Paul C. Nield, Timothy Devling, Rosalind E. Jenkins, B. Kevin Park, Radosław Polański, Nikolina Vlatković & Mark T. Boyd. (2008) MDM2 Regulates Dihydrofolate Reductase Activity through Monoubiquitination. Cancer Research 68:9, pages 3232-3242.
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Andrea Paradisi, Nicoletta Pasquariello, Daniela Barcaroli & Mauro Maccarrone. (2008) Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner. Journal of Biological Chemistry 283:10, pages 6005-6012.
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M Ehrlich, C B Woods, M C Yu, L Dubeau, F Yang, M Campan, D J Weisenberger, Ti Long, B Youn, E S Fiala & P W Laird. (2006) Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene 25:18, pages 2636-2645.
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Nicole Happel, Ekkehard Schulze & Detlef Doenecke. (2005) Characterisation of human histone H1x. Biological Chemistry 386:6.
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Kazue Tsuji-Takayama, Toshiya Inoue, Yoshihiro Ijiri, Takeshi Otani, Ryuichi Motoda, Shuji Nakamura & Kunzo Orita. (2004) Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells. Biochemical and Biophysical Research Communications 323:1, pages 86-90.
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Jianhua Zhao, Yan Yan, Konstantin Salnikow, Thomas Kluz & Max Costa. (2004) Nickel-induced down-regulation of serpin by hypoxic signaling. Toxicology and Applied Pharmacology 194:1, pages 60-68.
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Jiřı́ Hejnar, Daniel Elleder, Petra Hájková, Jörn Walter, Jana Blažková & Jan Svoboda. (2003) Demethylation of host-cell DNA at the site of avian retrovirus integration. Biochemical and Biophysical Research Communications 311:3, pages 641-648.
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Mohamed-Ali Hakimi, Daniel A. Bochar, John A. Schmiesing, Yuanshu Dong, Orr G. Barak, David W. Speicher, Kyoko Yokomori & Ramin Shiekhattar. (2002) A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature 418:6901, pages 994-998.
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John S. Mattick & Michael J. Gagen. (2001) The Evolution of Controlled Multitasked Gene Networks: The Role of Introns and Other Noncoding RNAs in the Development of Complex Organisms. Molecular Biology and Evolution 18:9, pages 1611-1630.
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Chien Chen, Mark C.K. Yang & Thomas P. Yang. (2001) Evidence That Silencing of the HPRT Promoter by DNA Methylation Is Mediated by Critical CpG Sites. Journal of Biological Chemistry 276:1, pages 320-328.
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