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Rakesh Verma, Madhusudan Venkatareddy, Anne Kalinowski, Sanjeevkumar R. Patel, David J. Salant & Puneet Garg. (2016) Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury. Molecular and Cellular Biology 36:4, pages 596-614.
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Zhiping Li, Chenguang Wang, Xuanmao Jiao, Yinan Lu, Maofu Fu, Andrew A. Quong, Chip Dye, Jianguo Yang, Maozheng Dai, Xiaoming Ju, Xueping Zhang, Anping Li, Peter Burbelo, E. Richard Stanley & Richard G. Pestell. (2006) Cyclin D1 Regulates Cellular Migration through the Inhibition of Thrombospondin 1 and ROCK Signaling. Molecular and Cellular Biology 26:11, pages 4240-4256.
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Gen-Sheng Feng. (2006) Shp2 as a therapeutic target for leptin resistance and obesity. Expert Opinion on Therapeutic Targets 10:1, pages 135-142.
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Ryouhei Tsutsumi, Atsushi Takahashi, Takeshi Azuma, Hideaki Higashi & Masanori Hatakeyama. (2006) Focal Adhesion Kinase Is a Substrate and Downstream Effector of SHP-2 Complexed with Helicobacter pylori CagA. Molecular and Cellular Biology 26:1, pages 261-276.
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Maria I. Kontaridis, Seda Eminaga, Mara Fornaro, Christina Ivins Zito, Raffaella Sordella, Jeffrey Settleman & Anton M. Bennett. (2004) SHP-2 Positively Regulates Myogenesis by Coupling to the Rho GTPase Signaling Pathway. Molecular and Cellular Biology 24:12, pages 5340-5352.
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Christine Didier, Limor Broday, Anindita Bhoumik, Sharon Israeli, Shoichi Takahashi, Koh Nakayama, Sheila M. Thomas, Christopher E. Turner, Scott Henderson, Hisataka Sabe & Ze'ev Ronai. (2003) RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization. Molecular and Cellular Biology 23:15, pages 5331-5345.
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Hwa-Ok Kim & Mark A Blaskovich. (2002) Recent discovery and development of protein tyrosine phosphatase inhibitors. Expert Opinion on Therapeutic Patents 12:6, pages 871-905.
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Si Qing Zhang, William G. Tsiaras, Toshiyuki Araki, Gengyun Wen, Liliana Minichiello, Ruediger Klein & Benjamin G. Neel. (2002) Receptor-Specific Regulation of Phosphatidylinositol 3′-Kinase Activation by the Protein Tyrosine Phosphatase Shp2. Molecular and Cellular Biology 22:12, pages 4062-4072.
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Johanna Ivaska, Liisa Nissinen, Nina Immonen, John E. Eriksson, Veli-Matti Kähäri & Jyrki Heino. (2002) Integrin α2β1 Promotes Activation of Protein Phosphatase 2A and Dephosphorylation of Akt and Glycogen Synthase Kinase 3β. Molecular and Cellular Biology 22:5, pages 1352-1359.
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Margit Hagel, Elizabeth L. George, Ann Kim, Rulla Tamimi, Sarah L. Opitz, Christopher E. Turner, Akira Imamoto & Sheila M. Thomas. (2002) The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin Signaling. Molecular and Cellular Biology 22:3, pages 901-915.
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Christiane R. Maroun, Monica A. Naujokas, Marina Holgado-Madruga, Albert J. Wong & Morag Park. (2000) The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase. Molecular and Cellular Biology 20:22, pages 8513-8525.
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Alana M. O'Reilly, Scott Pluskey, Steven E. Shoelson & Benjamin G. Neel. (2000) Activated Mutants of SHP-2 Preferentially Induce Elongation of Xenopus Animal Caps. Molecular and Cellular Biology 20:1, pages 299-311.
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Yijia Pan, Linda Zhixia Shi, Chi Woo Yoon, Daryl Preece, Veronica Gomez‐Godinez, Shaoying Lu, Christopher Carmona, Seung‐Hyun Woo, Shu Chien, Michael W Berns, Longwei Liu & Yingxiao Wang. (2022)
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Alexandra Mazharian, Jun Mori, Ying-Jie Wang, Silke Heising, Benjamin G. Neel, Steve P. Watson & Yotis A. Senis. (2013) Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function. Blood 121:20, pages 4205-4220.
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Stephanie M. Stanford, Michael F. Maestre, Amanda M. Campbell, Beatrix Bartok, William B. Kiosses, David L. Boyle, Heather A. Arnett, Tomas Mustelin, Gary S. Firestein & Nunzio Bottini. (2013) Protein Tyrosine Phosphatase Expression Profile of Rheumatoid Arthritis Fibroblast-like Synoviocytes: A Novel Role of SH2 Domain-Containing Phosphatase 2 as a Modulator of Invasion and Survival. Arthritis & Rheumatism 65:5, pages 1171-1180.
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Xiaoyun Fang, Yongjiang Lang, Yuxiong Wang, Wei Mo, Huanhuan Wei, Jianhui Xie & Min Yu. (2012) Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcεRI Aggregation. PLoS ONE 7:7, pages e40566.
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Hsien-Yu Peng, Gin-Den Chen, Cheng-Yuang Lai, Ming-Chun Hsieh & Tzer-Bin Lin. (2012) Spinal SIRPα1-SHP2 interaction regulates spinal nerve ligation-induced neuropathic pain via PSD-95-dependent NR2B activation in rats. Pain 153:5, pages 1042-1053.
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Per-Arne Oldenborg. (2012) Role of CD47 and Signal Regulatory Protein Alpha (SIRPa) in Regulating the Clearance of Viable or Aged Blood Cells. Transfusion Medicine and Hemotherapy 39:5, pages 315-320.
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Ying Yang, Beibei Jiang, Yingqing Huo, Luca Primo, Jean S. Dahl, Thomas L. Benjamin & Jincai Luo. (2011) Shp2 suppresses PyMT-induced transformation in mouse fibroblasts by inhibiting Stat3 activity. Virology 409:2, pages 204-210.
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Sonia Kapur, Mehran Amoui, Chandrasekhar Kesavan, Xiaoguang Wang, Subburaman Mohan, David J. Baylink & K.-H. William Lau. (2010) Leptin Receptor (Lepr) Is a Negative Modulator of Bone Mechanosensitivity and Genetic Variations in Lepr May Contribute to the Differential Osteogenic Response to Mechanical Stimulation in the C57BL/6J and C3H/HeJ Pair of Mouse Strains. Journal of Biological Chemistry 285:48, pages 37607-37618.
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Traci Galbaugh, Yvonne B. Feeney & Charles V. Clevenger. (2010) Prolactin Receptor–Integrin Cross-Talk Mediated by SIRPα in Breast Cancer Cells. Molecular Cancer Research 8:10, pages 1413-1424.
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G S Kapoor & D M O'Rourke. (2010) SIRPα1 receptors interfere with the EGFRvIII signalosome to inhibit glioblastoma cell transformation and migration. Oncogene 29:29, pages 4130-4144.
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Weiguo Chen, Joe G.N. Garcia & Jeffrey R. Jacobson. (2010) Integrin β4 attenuates SHP-2 and MAPK signaling and reduces human lung endothelial inflammatory responses. Journal of Cellular Biochemistry 110:3, pages 718-724.
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Nina Hanke, Hans-Peter Kubis, Renate J. Scheibe, Mark Berthold-Losleben, Olaf Hüsing, Joachim D. Meissner & Gerolf Gros. (2010) Passive mechanical forces upregulate the fast myosin heavy chain IId/x via integrin and p38 MAP kinase activation in a primary muscle cell culture. American Journal of Physiology-Cell Physiology 298:4, pages C910-C920.
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Kazuki Hagihara, Eric E. Zhang, Yue-Hai Ke, Guofa Liu, Jan-Jan Liu, Yi Rao & Gen-Sheng Feng. (2009) Shp2 acts downstream of SDF-1α/CXCR4 in guiding granule cell migration during cerebellar development. Developmental Biology 334:1, pages 276-284.
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Xinchun Shen, Gang Xi, Yashwanth Radhakrishnan & David R. Clemmons. (2009) Identification of Novel SHPS-1-associated Proteins and Their Roles in Regulation of Insulin-like Growth Factor-dependent Responses in Vascular Smooth Muscle Cells. Molecular & Cellular Proteomics 8:7, pages 1539-1551.
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Koji Yo, Satoshi Iwata, Yutaka Hashizume, Shunsuke Kondo, Sayaka Nomura, Osamu Hosono, Hiroshi Kawasaki, Hirotoshi Tanaka, Nam H. Dang & Chikao Morimoto. (2009) SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration. Biochemical and Biophysical Research Communications 382:1, pages 210-214.
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Richard D. Hayward, Peter J. Hume, Daniel Humphreys, Neil Phillips, Katherine Smith & Vassilis Koronakis. (2009)
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Siying Wang, Wen-Mei Yu, Wanming Zhang, Keith R. McCrae, Benjamin G. Neel & Cheng-Kui Qu. (2009) Noonan Syndrome/Leukemia-associated Gain-of-function Mutations in SHP-2 Phosphatase (PTPN11) Enhance Cell Migration and Angiogenesis. Journal of Biological Chemistry 284:2, pages 913-920.
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Yueping K Qian, Ariel WS Chan, Raghavan Madhavan & H Benjamin Peng. (2008) The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters. BMC Neuroscience 9:1.
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Nathalie Vacaresse, Bente Møller, E. Michael Danielsen, Masato Okada & Jan Sap. (2008) Activation of c-Src and Fyn Kinases by Protein-tyrosine Phosphatase RPTPα Is Substrate-specific and Compatible with Lipid Raft Localization. Journal of Biological Chemistry 283:51, pages 35815-35824.
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Talita M. MarinCarolina F.M.Z. ClementeAline M. SantosPaty K. PicardiVinícius D.B. PascoalIscia Lopes-CendesMário J.A. SaadKleber G. Franchini. (2008) Shp2 Negatively Regulates Growth in Cardiomyocytes by Controlling Focal Adhesion Kinase/Src and mTOR Pathways. Circulation Research 103:8, pages 813-824.
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X Zhou, J Coad, B Ducatman & Y M Agazie. (2008) SHP2 is up-regulated in breast cancer cells and in infiltrating ductal carcinoma of the breast, implying its involvement in breast oncogenesis. Histopathology 53:4, pages 389-402.
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Mariko Hirano, Shigeru Hashimoto, Shigenobu Yonemura, Hisataka Sabe & Shinichi Aizawa. (2008) EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition. Journal of Cell Biology 182:6, pages 1217-1230.
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Gang Xi, Xinchun Shen & David R. Clemmons. (2008) p66shc Negatively Regulates Insulin-Like Growth Factor I Signal Transduction via Inhibition of p52shc Binding to Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Substrate-1 Leading to Impaired Growth Factor Receptor-Bound Protein-2 Membrane Recruitment. Molecular Endocrinology 22:9, pages 2162-2175.
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X-D Zhou & Y M Agazie. (2008) Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells. Cell Death & Differentiation 15:6, pages 988-996.
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Gordon Chan, Demetrios Kalaitzidis & Benjamin G. Neel. (2008) The tyrosine phosphatase Shp2 (PTPN11) in cancer. Cancer and Metastasis Reviews 27:2, pages 179-192.
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Seda Eminaga & Anton M. Bennett. (2008) Noonan Syndrome-associated SHP-2/Ptpn11 Mutants Enhance SIRPα and PZR Tyrosyl Phosphorylation and Promote Adhesion-mediated ERK Activation. Journal of Biological Chemistry 283:22, pages 15328-15338.
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Gang Xi, Laura A. Maile, Sung-Eun Yoo & David R. Clemmons. (2008) Expression of the human β3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation. Journal of Cellular Physiology 214:2, pages 306-315.
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Naoto Seki, Naotake Hashimoto, Masato Taira, Sayaka Yagi, Yuriko Yoshida, Kou Ishikawa, Yoshifumi Suzuki, Hiroyuki Sano, Seikou Horiuchi, Shouji Yoshida, Kenichi Sakurai, Kazuo Yagui, Hideichi Makino & Yasushi Saito. (2007) Regulation of Src homology 2–containing protein tyrosine phosphatase by advanced glycation end products: the role on atherosclerosis in diabetes. Metabolism 56:11, pages 1591-1598.
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Maria G. Roubelakis, Enca Martin-Rendon, Grigorios Tsaknakis, Athanassios Stavropoulos & Suzanne M. Watt. (2007) The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation. Journal of Cellular Biochemistry 102:4, pages 955-969.
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Brian P. James, Thomas A. Bunch, Srinivasan Krishnamoorthy, Lizabeth A. Perkins & Danny L. Brower. (2007)
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Mette L. Johansen & Eric J. Brown. (2007) Dual Regulation of SIRPα Phosphorylation by Integrins and CD47. Journal of Biological Chemistry 282:33, pages 24219-24230.
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Maria Letizia TaddeiMatteo ParriTommaso MelloAlfonso CatalanoAlan D. LevineGiovanni RaugeiGiampietro RamponiPaola Chiarugi. (2007) Integrin-Mediated Cell Adhesion and Spreading Engage Different Sources of Reactive Oxygen Species. Antioxidants & Redox Signaling 9:4, pages 469-481.
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Mara Fornaro, Peter M. Burch, Wentian Yang, Lei Zhang, Claire E. Hamilton, Jung H. Kim, Benjamin G. Neel & Anton M. Bennett. (2006) SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth. Journal of Cell Biology 175:1, pages 87-97.
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Qin Wang, Maria Teresa Herrera Abreu, Katherine Siminovitch, Gregory P. Downey & Christopher A. McCulloch. (2006) Phosphorylation of SHP-2 Regulates Interactions between the Endoplasmic Reticulum and Focal Adhesions to Restrict Interleukin-1-induced Ca2+ Signaling. Journal of Biological Chemistry 281:41, pages 31093-31105.
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Christopher. A. McCulloch, Gregory P. Downey & Hani El-Gabalawy. (2006) Signalling platforms that modulate the inflammatory response: new targets for drug development. Nature Reviews Drug Discovery 5:10, pages 864-876.
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Keith Burridge, Sarita K. Sastry & Jennifer L. Sallee. (2006) Regulation of Cell Adhesion by Protein-tyrosine Phosphatases. Journal of Biological Chemistry 281:23, pages 15593-15596.
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Anna Janiak, Evgeny A. Zemskov & Alexey M. Belkin. (2006) Cell Surface Transglutaminase Promotes RhoA Activation via Integrin Clustering and Suppression of the Src–p190RhoGAP Signaling Pathway. Molecular Biology of the Cell 17:4, pages 1606-1619.
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Min Chen, Shirley C. Chen & Catherine J. Pallen. (2006) Integrin-induced Tyrosine Phosphorylation of Protein-tyrosine Phosphatase-α Is Required for Cytoskeletal Reorganization and Cell Migration. Journal of Biological Chemistry 281:17, pages 11972-11980.
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Ana-Maria Bamberger, Vassilis Minas, Sophia N. Kalantaridou, Jessica Radde, Helen Sadeghian, Thomas Löning, Ioannis Charalampopoulos, Jens Brümmer, Christoph Wagener, Christoph M. Bamberger, Heinrich M. Schulte, George P. Chrousos & Antonis Makrigiannakis. (2006) Corticotropin-Releasing Hormone Modulates Human Trophoblast Invasion through Carcinoembryonic Antigen-Related Cell Adhesion Molecule-1 Regulation. The American Journal of Pathology 168:1, pages 141-150.
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