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Molecular and Cellular Biology Volume 19, 1999 - Issue 5
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Cell Growth and Development

Retinoid X Receptor (RXR) Agonist-Induced Activation of Dominant-Negative RXR-Retinoic Acid Receptor α403 Heterodimers Is Developmentally Regulated during Myeloid Differentiation

Barton S. Johnson1 Division of Hospital Dentistry, University of Washington, Seattle, Washington98195
,
Roshantha A. S. Chandraratna2 Retinoid Research, Departments of Biology;3 Chemistry, Allergan Pharmaceuticals, Irvine, California92715
,
Richard A. Heyman4 Department of Retinoid Research, Ligand Pharmaceuticals, San Diego, California92121
,
Elizabeth A. Allegretto4 Department of Retinoid Research, Ligand Pharmaceuticals, San Diego, California92121
,
LeMoyne Mueller5 Division of Molecular Medicine, Fred Hutchinson Cancer Research Center, Seattle, Washington98109
&
Steven J. Collins5 Division of Molecular Medicine, Fred Hutchinson Cancer Research Center, Seattle, Washington98109Correspondence[email protected]
Pages 3372-3382 | Received 31 Aug 1998, Accepted 25 Jan 1999, Published online: 28 Mar 2023

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Reinhard Dummer, Marc Beyer, Kenneth Hymes, Mirjam T. Epping, Rene Bernards, Matthias Steinhoff, Wolfram Sterry, Helmut Kerl, Karl Heath, Janet D. Ahern, James S. Hardwick, Jose Garcia-Vargas, Katrin Baumann, Syed Rizvi, Stanley R. Frankel, Sean J. Whittaker & Chalid Assaf. (2012) Vorinostat combined with bexarotene for treatment of cutaneous T-cell lymphoma: in vitro and phase I clinical evidence supporting augmentation of retinoic acid receptor/retinoid X receptor activation by histone deacetylase inhibition. Leukemia & Lymphoma 53:8, pages 1501-1508.
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MingQiang Ren, Silvia Pozzi, Gaia Bistulfi, Giulia Somenzi, Stefano Rossetti & Nicoletta Sacchi. (2005) Impaired Retinoic Acid (RA) Signal Leads to RARβ2 Epigenetic Silencing and RA Resistance. Molecular and Cellular Biology 25:23, pages 10591-10603.
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Matthew R. Yudt, Christine M. Jewell, Rachelle J. Bienstock & John A. Cidlowski. (2003) Molecular Origins for the Dominant Negative Function of Human Glucocorticoid Receptor Beta. Molecular and Cellular Biology 23:12, pages 4319-4330.
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Grant A. McArthur, Kevin P. Foley, Matthew L. Fero, Carl R. Walkley, Andrew J. Deans, James M. Roberts & Robert N. Eisenman. (2002) MAD1 and p27KIP1 Cooperate To Promote Terminal Differentiation of Granulocytes and To Inhibit Myc Expression and Cyclin E-CDK2 Activity. Molecular and Cellular Biology 22:9, pages 3014-3023.
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Jutong Si, LeMoyne Mueller & Steven J. Collins. (2007) CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells. Journal of Clinical Investigation 117:5, pages 1412-1421.
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A Szanto, V Narkar, Q Shen, I P Uray, P J A Davies & L Nagy. (2004) Retinoid X receptors: X-ploring their (patho)physiological functions. Cell Death & Differentiation 11:S2, pages S126-S143.
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RE Gallagher. (2002) Retinoic acid resistance in acute promyelocytic leukemia. Leukemia 16:10, pages 1940-1958.
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SJ Collins. (2002) The role of retinoids and retinoic acid receptors in normal hematopoiesis. Leukemia 16:10, pages 1896-1905.
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Charles B. Stephensen, Reuven Rasooly, Xiaowen Jiang, Michael A. Ceddia, Casey T. Weaver, Roshantha A. S. Chandraratna & R. Patterson Bucy. (2002) Vitamin A Enhances in Vitro Th2 Development Via Retinoid X Receptor Pathway. The Journal of Immunology 168:9, pages 4495-4503.
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Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 248 272 .
Daniel R Barreda & Miodrag Belosevic. (2001) Transcriptional regulation of hemopoiesis. Developmental & Comparative Immunology 25:8-9, pages 763-789.
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Michiko Muramatsu, Yutaka Hanazono, Yoji Ogasawara, Takashi Okada, Hiroaki Mizukami, Akihiro Kume, Hideaki Mizoguchi & Keiya Ozawa. (2001) Reversible Integration of the Dominant Negative Retinoid Receptor Gene for ex Vivo Expansion of Hematopoietic Stem/Progenitor Cells. Biochemical and Biophysical Research Communications 285:4, pages 891-896.
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Ulrich Kintscher, Stephan Goetze, Shu Wakino, Sarah Kim, Sunil Nagpal, Roshantha A.S Chandraratna, Kristof Graf, Eckart Fleck, Willa A Hsueh & Ronald E Law. (2000) Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes. European Journal of Pharmacology 401:3, pages 259-270.
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Philippe Goyette, Chang Feng Chen, Wei Wang, Francois Seguin & David Lohnes. (2000) Characterization of Retinoic Acid Receptor-deficient Keratinocytes. Journal of Biological Chemistry 275:22, pages 16497-16505.
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