27
Views
133
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Molecular Determinants of the Estrogen Receptor-Coactivator Interface

, , &
Pages 3895-3903 | Received 15 Dec 1998, Accepted 12 Feb 1999, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (19)

Qingtian Li, Mei-Jin Chu & Jianming Xu. (2007) Tissue- and Nuclear Receptor-Specific Function of the C-Terminal LXXLL Motif of Coactivator NCoA6/AIB3 in Mice. Molecular and Cellular Biology 27:23, pages 8073-8086.
Read now
Silvia Carbonell Sala, Valentina Martineti, Anna Maria Carossino & Maria Luisa Brandi. (2007) Genetics and pharmacogenetics of estrogen response. Expert Review of Endocrinology & Metabolism 2:4, pages 503-516.
Read now
Fuzhong F. Zheng, Ray-Chang Wu, Carolyn L. Smith & Bert W. O'Malley. (2005) Rapid Estrogen-Induced Phosphorylation of the SRC-3 Coactivator Occurs in an Extranuclear Complex Containing Estrogen Receptor. Molecular and Cellular Biology 25:18, pages 8273-8284.
Read now
Borja Belandia, Sue M. Powell, Juana M. García-Pedrero, Marjorie M. Walker, Charlotte L. Bevan & Malcolm G. Parker. (2005) Hey1, a Mediator of Notch Signaling, Is an Androgen Receptor Corepressor. Molecular and Cellular Biology 25:4, pages 1425-1436.
Read now
Maggie C. Louie, June X. Zou, Alina Rabinovich & Hong-Wu Chen. (2004) ACTR/AIB1 Functions as an E2F1 Coactivator To Promote Breast Cancer Cell Proliferation and Antiestrogen Resistance. Molecular and Cellular Biology 24:12, pages 5157-5171.
Read now
David M. Lonard, Sophia Y. Tsai & Bert W. O'Malley. (2004) Selective Estrogen Receptor Modulators 4-Hydroxytamoxifen and Raloxifene Impact the Stability and Function of SRC-1 and SRC-3 Coactivator Proteins. Molecular and Cellular Biology 24:1, pages 14-24.
Read now
Bin He & Elizabeth M. Wilson. (2003) Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs. Molecular and Cellular Biology 23:6, pages 2135-2150.
Read now
Taiga Suzuki, Megumi Kasahara, Hidefumi Yoshioka, Ken-ichirou Morohashi & Kazuhiko Umesono. (2003) LXXLL-Related Motifs in Dax-1 Have Target Specificity for the Orphan Nuclear Receptors Ad4BP/SF-1 and LRH-1. Molecular and Cellular Biology 23:1, pages 238-249.
Read now
Muktar A. Mahajan, Audrey Murray & Herbert H. Samuels. (2002) NRC-Interacting Factor 1 Is a Novel Cotransducer That Interacts with and Regulates the Activity of the Nuclear Hormone Receptor Coactivator NRC. Molecular and Cellular Biology 22:19, pages 6883-6894.
Read now
Anna N. Moraitis, Vincent Giguère & Catherine C. Thompson. (2002) Novel Mechanism of Nuclear Receptor Corepressor Interaction Dictated by Activation Function 2 Helix Determinants. Molecular and Cellular Biology 22:19, pages 6831-6841.
Read now
Eric Kalkhoven, Hans Teunissen, Ada Houweling, C. Peter Verrijzer & Alt Zantema. (2002) The PHD Type Zinc Finger Is an Integral Part of the CBP Acetyltransferase Domain. Molecular and Cellular Biology 22:7, pages 1961-1970.
Read now
David L. Stenoien, Anne C. Nye, Maureen G. Mancini, Kavita Patel, Martin Dutertre, Bert W. O'Malley, Carolyn L. Smith, Andrew S. Belmont & Michael A. Mancini. (2001) Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells. Molecular and Cellular Biology 21:13, pages 4404-4412.
Read now
Ho Yi Mak & Malcolm G. Parker. (2001) Use of Suppressor Mutants To Probe the Function of Estrogen Receptor-p160 Coactivator Interactions. Molecular and Cellular Biology 21:13, pages 4379-4390.
Read now
Frédéric Sauvé, Linda D. B. McBroom, Josette Gallant, Anna N. Moraitis, Fernand Labrie & Vincent Giguère. (2001) CIA, a Novel Estrogen Receptor Coactivator with a Bifunctional Nuclear Receptor Interacting Determinant. Molecular and Cellular Biology 21:1, pages 343-353.
Read now
Yunsheng Ren, Evan Behre, Zhaojun Ren, Jiachang Zhang, Qianben Wang & Joseph D. Fondell. (2000) Specific Structural Motifs Determine TRAP220 Interactions with Nuclear Hormone Receptors. Molecular and Cellular Biology 20:15, pages 5433-5446.
Read now
Jaime Font de Mora & Myles Brown. (2000) AIB1 Is a Conduit for Kinase-Mediated Growth Factor Signaling to the Estrogen Receptor. Molecular and Cellular Biology 20:14, pages 5041-5047.
Read now
Christophe Rachez, Matthew Gamble, Chao-Pei Betty Chang, G. Brandon Atkins, Mitchell A. Lazar & Leonard P. Freedman. (2000) The DRIP Complex and SRC-1/p160 Coactivators Share Similar Nuclear Receptor Binding Determinants but Constitute Functionally Distinct Complexes. Molecular and Cellular Biology 20:8, pages 2718-2726.
Read now
Lotta Johansson, Ann Båvner, Jane S. Thomsen, Mathias Färnegårdh, Jan-Åke Gustafsson & Eckardt Treuter. (2000) The Orphan Nuclear Receptor SHP Utilizes Conserved LXXLL-Related Motifs for Interactions with Ligand-Activated Estrogen Receptors. Molecular and Cellular Biology 20:4, pages 1124-1133.
Read now
Charlotte L. Bevan, Sue Hoare, Frank Claessens, David M. Heery & Malcolm G. Parker. (1999) The AF1 and AF2 Domains of the Androgen Receptor Interact with Distinct Regions of SRC1. Molecular and Cellular Biology 19:12, pages 8383-8392.
Read now

Articles from other publishers (114)

Albert Grinshpun, Vincent Chen, Zachary M. Sandusky, Sean W. Fanning & Rinath Jeselsohn. (2023) ESR1 activating mutations: From structure to clinical application. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:1, pages 188830.
Crossref
Hannah P. Priyanka, A. Thiyagaraj, G. Krithika, R. S. Nair, W. Hopper & S. ThyagaRajan. (2022) 17β-Estradiol Concentration and Direct β 2 -Adrenoceptor Inhibition Determine Estrogen-Mediated Reversal of Adrenergic Immunosuppression . Annals of Neurosciences 29:1, pages 32-52.
Crossref
Chandra K. Maharjan, Jiao Mo, Lei Wang, Myung-Chul Kim, Sameul Wang, Nicholas Borcherding, Praveen Vikas & Weizhou Zhang. (2021) Natural and Synthetic Estrogens in Chronic Inflammation and Breast Cancer. Cancers 14:1, pages 206.
Crossref
Christian Derntl, Robert Mach & Astrid Mach-Aigner. (2020) Application of the human estrogen receptor within a synthetic transcription factor in Trichoderma reesei. Fungal Biology and Biotechnology 7:1.
Crossref
Yukitomo Arao & Kenneth S. Korach. (2019) Transactivation Function-1-Mediated Partial Agonist Activity of Selective Estrogen Receptor Modulator Requires Homo-Dimerization of the Estrogen Receptor α Ligand Binding Domain. International Journal of Molecular Sciences 20:15, pages 3718.
Crossref
Amanda Rui En Woo, Siu Kwan Sze, Hwa Hwa Chung & Valerie C-L Lin. (2019) Delineation of critical amino acids in activation function 1 of progesterone receptor for recruitment of transcription coregulators. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:4, pages 522-533.
Crossref
Ian Mitchelle S. de Vera, Udayanga S. Wanninayake & Thomas P. Burris. 2019. Estrogen Receptor and Breast Cancer. Estrogen Receptor and Breast Cancer 241 263 .
Rocío G. Sampayo, Andrés M. Toscani, Matthew G. Rubashkin, Kate Thi, Luciano A. Masullo, Ianina L. Violi, Jonathon N. Lakins, Alfredo Cáceres, William C. Hines, Federico Coluccio Leskow, Fernando D. Stefani, Dante R. Chialvo, Mina J. Bissell, Valerie M. Weaver & Marina Simian. (2018) Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells. Journal of Cell Biology 217:8, pages 2777-2798.
Crossref
Pelin Yaşar, Gamze Ayaz, Sırma Damla User, Gizem Güpür & Mesut Muyan. (2017) Molecular mechanism of estrogen-estrogen receptor signaling. Reproductive Medicine and Biology 16:1, pages 4-20.
Crossref
Pelin Yaşar, Gamze Ayaz & Mesut Muyan. (2016) Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway. Scientific Reports 6:1.
Crossref
Yukitomo Arao, Laurel A. Coons, William J. Zuercher & Kenneth S. Korach. (2015) Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element. Journal of Biological Chemistry 290:28, pages 17611-17627.
Crossref
Katsumi Toda, Yoshihiro Hayashi, Atsuko Yamashita, Masaru Okabe, Masafumi Ono & Toshiji Saibara. (2013) Aromatase-null mice expressing enhanced green fluorescent protein in germ cells provide a model system to assess estrogen-dependent ovulatory responses. Transgenic Research 23:2, pages 293-302.
Crossref
Fraydoon Rastinejad, Pengxiang Huang, Vikas Chandra & Sepideh Khorasanizadeh. (2013) Understanding nuclear receptor form and function using structural biology. Journal of Molecular Endocrinology 51:3, pages T1-T21.
Crossref
Ji-Hye Yun, Chul-Jin Lee, Jin-Won Jung & Weon-Tae Lee. (2012) Solution Structure of LXXLL-related Cofactor Peptide of Orphan Nuclear Receptor FTZ-F1. Bulletin of the Korean Chemical Society 33:2, pages 583-588.
Crossref
Alexander Endler, Li Chen, Jun Zhang, Guo-Tong Xu & Futoshi Shibasaki. (2012) A Novel Binding Site for hERalpha and hARNT1 AF2 Domains in the C-terminus of SRC1e Up-regulates Estrogen Receptor Alpha and AhR/ARNT1 Related Responses. Journal of Cell Science.
Crossref
Jiho Yoo, Sunggeon Ko, Hyeyon Kim, Heidi Sampson, Ji-Hye Yun, Kwang-Min Choe, Iksoo Chang, Cheryl H. Arrowsmith, Henry M. Krause, Hyun-Soo Cho & Weontae Lee. (2011) Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors. Journal of Biological Chemistry 286:36, pages 31225-31231.
Crossref
Peng Yuan, Kaiwei Liang, Buyong Ma, Nan Zheng, Ruth Nussinov & Jian Huang. (2011) Multiple-Targeting and Conformational Selection in the Estrogen Receptor: Computation and Experiment. Chemical Biology & Drug Design 78:1, pages 137-149.
Crossref
Terry W. Moore, Christopher G. Mayne & John A. Katzenellenbogen. (2010) Minireview: Not Picking Pockets: Nuclear Receptor Alternate-Site Modulators (NRAMs). Molecular Endocrinology 24:4, pages 683-695.
Crossref
Barry S. Komm, Boris Cheskis & Peter V.N. Bodine. 2010. Fundamentals of Osteoporosis. Fundamentals of Osteoporosis 345 385 .
Stefan Nilsson & Jan-Åke Gustafsson. 2010. Nuclear Receptors. Nuclear Receptors 91 141 .
Stephan Ellmann, Heinrich Sticht, Falk Thiel, Matthias W. Beckmann, Reiner Strick & Pamela L. Strissel. (2009) Estrogen and progesterone receptors: from molecular structures to clinical targets. Cellular and Molecular Life Sciences 66:15, pages 2405-2426.
Crossref
Terry W. Moore & John A. Katzenellenbogen. 2009. Annual Reports in Medicinal Chemistry Volume 44. Annual Reports in Medicinal Chemistry Volume 44 443 457 .
Gerrit H. Veeneman. 2008. Nuclear Receptors as Drug Targets. Nuclear Receptors as Drug Targets 65 126 .
Marco Lodrini, Tobias Münz, Nicolas Coudevylle, Christian Griesinger, Stefan Becker & Edith Pfitzner. (2008) p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain. Nucleic Acids Research 36:6, pages 1847-1860.
Crossref
BARRY S. KOMM, BORIS CHESKIS & PETER V.N. BODINE. 2008. Osteoporosis. Osteoporosis 383 423 .
Jing Peng & V. Craig Jordan. 2008. Principles of Molecular Oncology. Principles of Molecular Oncology 189 206 .
G. Luboshits & D. Benayahu. (2007) MS-KIF18A, a kinesin, is associated with estrogen receptor. Journal of Cellular Biochemistry 100:3, pages 693-702.
Crossref
Stéphanie Gaillard, Mary A. Dwyer & Donald P. McDonnell. (2007) Definition of the Molecular Basis for Estrogen Receptor-Related Receptor-α-Cofactor Interactions. Molecular Endocrinology 21:1, pages 62-76.
Crossref
Basem M. Jaber, Tong Gao, Luping Huang, Sudipan Karmakar & Carolyn L. Smith. (2006) The Pure Estrogen Receptor Antagonist ICI 182,780 Promotes a Novel Interaction of Estrogen Receptor-α with the 3′,5′-Cyclic Adenosine Monophosphate Response Element-Binding Protein-Binding Protein/p300 Coactivators. Molecular Endocrinology 20:11, pages 2695-2710.
Crossref
Michele Raviscioni, Qiang He, Eleni M. Salicru, Carolyn L. Smith & Olivier Lichtarge. (2006) Evolutionary identification of a subtype specific functional site in the ligand binding domain of steroid receptors. Proteins: Structure, Function, and Bioinformatics 64:4, pages 1046-1057.
Crossref
Paolo Ascenzi, Alessio Bocedi & Maria Marino. (2006) Structure–function relationship of estrogen receptor α and β: Impact on human health. Molecular Aspects of Medicine 27:4, pages 299-402.
Crossref
Tania-Noelia Noguerol, Susanna Boronat, Marta Casado, Demetrio Raldúa, Damià Barceló & Benjamin Piña. (2006) Evaluating the interactions of vertebrate receptors with persistent pollutants and antifouling pesticides using recombinant yeast assays. Analytical and Bioanalytical Chemistry 385:6, pages 1012-1019.
Crossref
Hui Liu, Kenian Liu & Donald L. Bodenner. (2005) Estrogen receptor inhibits interleukin-6 gene expression by disruption of nuclear factor κB transactivation. Cytokine 31:4, pages 251-257.
Crossref
Anobel Tamrazi, Kathryn E. Carlson, Alice L. Rodriguez & John A. Katzenellenbogen. (2005) Coactivator Proteins as Determinants of Estrogen Receptor Structure and Function: Spectroscopic Evidence for a Novel Coactivator-Stabilized Receptor Conformation. Molecular Endocrinology 19:6, pages 1516-1528.
Crossref
Jeongeun Eun Lee, Kyounghyun Kim, James C. Sacchettini, Clare V. Smith & Stephen Safe. (2005) DRIP150 Coactivation of Estrogen Receptor α in ZR-75 Breast Cancer Cells Is Independent of LXXLL Motifs. Journal of Biological Chemistry 280:10, pages 8819-8830.
Crossref
Gregg D. Cappon, Masao Horimoto & Mark E. Hurtt. (2004) Reproductive toxicity assessment of lasofoxifene, a selective estrogen receptor modulator (SERM), in male rats. Birth Defects Research Part B: Developmental and Reproductive Toxicology 71:3, pages 142-149.
Crossref
Ying Liu, Byung Oh Kim, Chinghai Kao, Chaeyong Jung, James T. Dalton & Johnny J. He. (2004) Tip110, the Human Immunodeficiency Virus Type 1 (HIV-1) Tat-interacting Protein of 110 kDa as a Negative Regulator of Androgen Receptor (AR) Transcriptional Activation. Journal of Biological Chemistry 279:21, pages 21766-21773.
Crossref
Ira G Schulman & Richard A Heyman. (2004) The Flip Side. Chemistry & Biology 11:5, pages 639-646.
Crossref
Zafar Nawaz & Bert W. O’Malley. (2004) Urban Renewal in the Nucleus: Is Protein Turnover by Proteasomes Absolutely Required for Nuclear Receptor-Regulated Transcription?. Molecular Endocrinology 18:3, pages 493-499.
Crossref
Martin L. Privalsky. (2004) The Role of Corepressors in Transcriptional Regulation by Nuclear Hormone Receptors. Annual Review of Physiology 66:1, pages 315-360.
Crossref
R.S. Savkur & T.P. Burris. (2004) The coactivator LXXLL nuclear receptor recognition motif. Journal of Peptide Research 63:3, pages 207-212.
Crossref
Carolyn L. Smith & Bert W. O’Malley. (2004) Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators. Endocrine Reviews 25:1, pages 45-71.
Crossref
Dangsheng Li, Tatsuya Yamada, Fang Wang, A. Igor Vulin & Herbert H. Samuels. (2004) Novel Roles of Retinoid X Receptor (RXR) and RXR Ligand in Dynamically Modulating the Activity of the Thyroid Hormone Receptor/RXR Heterodimer. Journal of Biological Chemistry 279:9, pages 7427-7437.
Crossref
Rajesh S Savkur, Kelli S Bramlett, David Clawson & Thomas P Burris. 2004. Nuclear Receptor Coregulators. Nuclear Receptor Coregulators 145 183 .
Carolyn L. Smith. 2004. Cancer Chemoprevention. Cancer Chemoprevention 245 256 .
Jennifer E. Fox, Hong Liu & V. Craig Jordan. 2004. Principles of Molecular Oncology. Principles of Molecular Oncology 317 358 .
Susan Kunz, Robert Sandoval, Peter Carlsson, Jan Carlstedt-Duke, John W. Bloom & Roger L. Miesfeld. (2003) Identification of a Novel Glucocorticoid Receptor Mutation in Budesonide-Resistant Human Bronchial Epithelial Cells. Molecular Endocrinology 17:12, pages 2566-2582.
Crossref
Anne-Marie Leduc, John O. Trent, James L. Wittliff, Kelli S. Bramlett, Stephen L. Briggs, Nikolay Y. Chirgadze, Yong Wang, Thomas P. Burris & Arno F. Spatola. (2003) Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor–coactivator interactions. Proceedings of the National Academy of Sciences 100:20, pages 11273-11278.
Crossref
Richard J. Santen. (2003) Inhibition of aromatase: insights from recent studies. Steroids 68:7-8, pages 559-567.
Crossref
MICHAEL W. DRAPER & WILLIAM W. CHIN. (2003) Molecular and Clinical Evidence for the Unique Nature of Individual Selective Estrogen Receptor Modulators. Clinical Obstetrics and Gynecology 46:2, pages 265-297.
Crossref
Naoko Kanda & Shinichi Watanabe. (2003) 17beta-Estradiol Inhibits MCP-1 Production in Human Keratinocytes. Journal of Investigative Dermatology 120:6, pages 1058-1066.
Crossref
Naoko Kanda & Shinichi Watanabe. (2003) 17β-Estradiol Inhibits MCP-1 Production in Human Keratinocytes. Journal of Investigative Dermatology 120:6, pages 1058-1066.
Crossref
Boris J. Cheskis, Neil J. McKenna, Chi-Wai Wong, Jiemin Wong, Barry Komm, C. Richard Lyttle & Bert W. O'Malley. (2003) Hierarchical Affinities and a Bipartite Interaction Model for Estrogen Receptor Isoforms and Full-length Steroid Receptor Coactivator (SRC/p160) Family Members. Journal of Biological Chemistry 278:15, pages 13271-13277.
Crossref
Stefan O. Mueller, Julie M. Hall, Deborah L. Swope, Lars C. Pedersen & Kenneth S. Korach. (2003) Molecular Determinants of the Stereoselectivity of Agonist Activity of Estrogen Receptors (ER) α and ॆ. Journal of Biological Chemistry 278:14, pages 12255-12262.
Crossref
Victoria H. Coulthard, Sachiko Matsuda & David M. Heery. (2003) An Extended LXXLL Motif Sequence Determines the Nuclear Receptor Binding Specificity of TRAP220. Journal of Biological Chemistry 278:13, pages 10942-10951.
Crossref
Yifei Wu, William W. Chin, Yong Wang & Thomas P. Burris. (2003) Ligand and Coactivator Identity Determines the Requirement of the Charge Clamp for Coactivation of the Peroxisome Proliferator-activated Receptor γ. Journal of Biological Chemistry 278:10, pages 8637-8644.
Crossref
Zhilei Chen & Huimin Zhao. (2003) A highly efficient and sensitive screening method for trans-activation activity of estrogen receptors. Gene 306, pages 127-134.
Crossref
Paul Webb, Phuong Nguyen & Peter J. Kushner. (2003) Differential SERM Effects on Corepressor Binding Dictate ERα Activity in Vivo. Journal of Biological Chemistry 278:9, pages 6912-6920.
Crossref
Deborah A Lannigan. (2003) Estrogen receptor phosphorylation. Steroids 68:1, pages 1-9.
Crossref
Laura F. Su, Zhen Wang & Michael J. Garabedian. (2002) Regulation of GRIP1 and CBP Coactivator Activity by Rho GDI Modulates Estrogen Receptor Transcriptional Enhancement. Journal of Biological Chemistry 277:40, pages 37037-37044.
Crossref
Sten Z. Cekan. (2002) Genes and transcription factors, including nuclear receptors: Methods of studying their interactions. Journal of Laboratory and Clinical Medicine 140:4, pages 215-227.
Crossref
Erika Krasnickas Keeton, Terace M. Fletcher, Christopher T. Baumann, Gordon L. Hager & Catharine L. Smith. (2002) Glucocorticoid Receptor Domain Requirements for Chromatin Remodeling and Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter in Different Nucleoprotein Contexts. Journal of Biological Chemistry 277:31, pages 28247-28255.
Crossref
Laura L Hart & James R Davie. (2002) The estrogen receptor: more than the average transcription factor. Biochemistry and Cell Biology 80:3, pages 335-341.
Crossref
Anette Wärnmark, Eckardt Treuter, Jan-Åke Gustafsson, Roderick E. Hubbard, Andrzej M. Brzozowski & Ashley C.W. Pike. (2002) Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor α. Journal of Biological Chemistry 277:24, pages 21862-21868.
Crossref
Jonathan M. Harris, Patrick Lau, Shen Liang Chen & George E. O. Muscat. (2002) Characterization of the Retinoid Orphan-Related Receptor-α Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription. Molecular Endocrinology 16:5, pages 998-1012.
Crossref
Patrick Diel. (2002) Tissue-specific estrogenic response and molecular mechanisms. Toxicology Letters 127:1-3, pages 217-224.
Crossref
Bradley Saville, Hetti Poukka, Mark Wormke, Olli A. Jänne, Jorma J. Palvimo, Matthew Stoner, Ismael Samudio & Stephen Safe. (2002) Cooperative Coactivation of Estrogen Receptor α in ZR-75 Human Breast Cancer Cells by SNURF and TATA-binding Protein. Journal of Biological Chemistry 277:4, pages 2485-2497.
Crossref
David M. Lonard & Carolyn L. Smith. (2002) Molecular perspectives on selective estrogen receptor modulators (SERMs): progress in understanding their tissue-specific agonist and antagonist actions. Steroids 67:1, pages 15-24.
Crossref
Neal G. Simon. 2002. Hormones, Brain and Behavior. Hormones, Brain and Behavior 339 I .
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 308 335 .
Paul Webb. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 57 76 .
Stefan Nilsson & Jan-Åke Gustafsson. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 3 18 .
Michael J. Garabedian, Inez Rogatsky & Janet M. Trowbridge. 2002. Steroid Hormones and Cell Cycle Regulation. Steroid Hormones and Cell Cycle Regulation 239 257 .
Miki Maeda. (2001) The conserved residues of the ligand-binding domains of steroid receptors are located in the core of the molecules. Journal of Molecular Graphics and Modelling 19:6, pages 543-551.
Crossref
Taiga Suzuki, Haruhisa Kawasaki, Ruth T. Yu, Hitoshi Ueda & Kazuhiko Umesono. (2001) Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1. Proceedings of the National Academy of Sciences 98:22, pages 12403-12408.
Crossref
Ashini L. Wijayaratne & Donald P. McDonnell. (2001) The Human Estrogen Receptor-α Is a Ubiquitinated Protein Whose Stability Is Affected Differentially by Agonists, Antagonists, and Selective Estrogen Receptor Modulators. Journal of Biological Chemistry 276:38, pages 35684-35692.
Crossref
Jennifer R. Wood, Varsha S. Likhite, Margaret A. Loven & Ann M. Nardulli. (2001) Allosteric Modulation of Estrogen Receptor Conformation by Different Estrogen Response Elements. Molecular Endocrinology 15:7, pages 1114-1126.
Crossref
Kelli S. Bramlett, Yifei Wu & Thomas P. Burris. (2001) Ligands Specify Coactivator Nuclear Receptor (NR) Box Affinity for Estrogen Receptor Subtypes. Molecular Endocrinology 15:6, pages 909-922.
Crossref
Anette Wärnmark, Tova Almlöf, Jörg Leers, Jan-Åke Gustafsson & Eckardt Treuter. (2001) Differential Recruitment of the Mammalian Mediator Subunit TRAP220 by Estrogen Receptors ERα and ERβ. Journal of Biological Chemistry 276:26, pages 23397-23404.
Crossref
Monika Jakacka, Masafumi Ito, Jeffrey Weiss, Pei-Yu Chien, Barry D. Gehm & J. Larry Jameson. (2001) Estrogen Receptor Binding to DNA Is Not Required for Its Activity through the Nonclassical AP1 Pathway. Journal of Biological Chemistry 276:17, pages 13615-13621.
Crossref
Lars Brive, David B. Agus & Kathryn R. Ely. (2002) Structure-Based Androgen Receptor Gene Mutation Database: A Tool to Link Molecular Location and Receptor Function. The Prostate Journal 3:2, pages 76-91.
Crossref
Katarina PetterssonJan-Åke Gustafsson. (2001) Role of Estrogen Receptor Beta in Estrogen Action. Annual Review of Physiology 63:1, pages 165-192.
Crossref
David M. Heery, Susan Hoare, Sagair Hussain, Malcolm G. Parker & Hilary Sheppard. (2001) Core LXXLL Motif Sequences in CREB-binding Protein, SRC1, and RIP140 Define Affinity and Selectivity for Steroid and Retinoid Receptors. Journal of Biological Chemistry 276:9, pages 6695-6702.
Crossref
Ashley C.W. Pike, A.Marek Brzozowski, Julia Walton, Roderick E. Hubbard, Ann-Gerd Thorsell, Yi-Lin Li, Jan-Åke Gustafsson & Mats Carlquist. (2001) Structural Insights into the Mode of Action of a Pure Antiestrogen. Structure 9:2, pages 145-153.
Crossref
Emmanuel Margeat, Nicolas Poujol, Abdelhay Boulahtouf, Yan Chen, Joachim D Müller, Enrico Gratton, Vincent Cavailles & Catherine A Royer. (2001) The human estrogen receptor α dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure11Edited by K. Yamamoto. Journal of Molecular Biology 306:3, pages 433-442.
Crossref
Stefan Nilsson, Sari Mäkelä, Eckardt Treuter, Michel Tujague, Jane Thomsen, Göran Andersson, Eva Enmark, Katarina Pettersson, Margaret Warner & Jan-Åke Gustafsson. (2001) Mechanisms of Estrogen Action. Physiological Reviews 81:4, pages 1535-1565.
Crossref
David L. Stenoien, Kavita Patel, Maureen G. Mancini, Martin Dutertre, Carolyn L. Smith, Bert W. O'Malley & Michael A. Mancini. (2000) FRAP reveals that mobility of oestrogen receptor-α is ligand- and proteasome-dependent. Nature Cell Biology 3:1, pages 15-23.
Crossref
Barry S. Komm & Peter V.N. Bodine. 2001. Osteoporosis. Osteoporosis 305 337 .
David M. Lonard & Zafar Nawaz. 2001. Nuclear Receptors and Genetic Disease. Nuclear Receptors and Genetic Disease 389 408 .
M. L. Privalsky. 2001. Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression. Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression 117 136 .
Peter J Kushner, David A Agard, Geoffrey L Greene, Thomas S Scanlan, Andrew K Shiau, Rosalie M Uht & Paul Webb. (2000) Estrogen receptor pathways to AP-1. The Journal of Steroid Biochemistry and Molecular Biology 74:5, pages 311-317.
Crossref
Ashley C.W Pike, Andrzej M Brzozowski & Roderick E Hubbard. (2000) A structural biologist's view of the oestrogen receptor. The Journal of Steroid Biochemistry and Molecular Biology 74:5, pages 261-268.
Crossref
Dennis M. Kraichely, Jun Sun, John A. Katzenellenbogen & Benita S. Katzenellenbogen. (2000) Conformational Changes and Coactivator Recruitment by Novel Ligands for Estrogen Receptor-α and Estrogen Receptor-β: Correlations with Biological Character and Distinct Differences among SRC Coactivator Family Members*. Endocrinology 141:10, pages 3534-3545.
Crossref
Stefan Nilsson & Jan-Åke Gustafsson. (2000) Estrogen receptor transcription and transactivation Basic aspects of estrogen action. Breast Cancer Research 2:5.
Crossref
Valentyn V. Tyulmenkov & Carolyn M. Klinge. (2000) Interaction of Tetrahydrocrysene Ketone with Estrogen Receptors α and β Indicates Conformational Differences in the Receptor Subtypes. Archives of Biochemistry and Biophysics 381:1, pages 135-142.
Crossref
Joyce Lim, Farid J. Ghadessy, Abdullah A. R. Abdullah, Leonard Pinsky, Mark Trifiro & E. L. Yong. (2000) Human Androgen Receptor Mutation Disrupts Ternary Interactions between Ligand, Receptor Domains, and the Coactivator TIF2 (Transcription Intermediary Factor 2). Molecular Endocrinology 14:8, pages 1187-1197.
Crossref
Janet E. Valentine, Eric Kalkhoven, Roger White, Sue Hoare & Malcolm G. Parker. (2000) Mutations in the Estrogen Receptor Ligand Binding Domain Discriminate between Hormone-dependent Transactivation and Transrepression. Journal of Biological Chemistry 275:33, pages 25322-25329.
Crossref
Per E. L??nning. (2000) Is There a Growing Role for Endocrine Therapy in the Treatment of Breast Cancer?. Drugs 60:1, pages 11-21.
Crossref
Bin He, Jon A. Kemppainen & Elizabeth M. Wilson. (2000) FXXLF and WXXLF Sequences Mediate the NH2-terminal Interaction with the Ligand Binding Domain of the Androgen Receptor. Journal of Biological Chemistry 275:30, pages 22986-22994.
Crossref
Silvia I. Anghel, Véronique Perly, Geneviève Melançon, Annie Barsalou, Samuel Chagnon, Angelika Rosenauer, Wilson H. MillerJr.Jr. & Sylvie Mader. (2000) Aspartate 351 of Estrogen Receptor α Is Not Crucial for the Antagonist Activity of Antiestrogens. Journal of Biological Chemistry 275:27, pages 20867-20872.
Crossref
Ulrika Lind, Paulette Greenidge, Mikael Gillner, Konrad F. Koehler, Anthony Wright & Jan Carlstedt-Duke. (2000) Functional Probing of the Human Glucocorticoid Receptor Steroid-interacting Surface by Site-directed Mutagenesis. Journal of Biological Chemistry 275:25, pages 19041-19049.
Crossref
David M Lonard, Zafar Nawaz, Carolyn L Smith & Bert W O'Malley. (2000) The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation. Molecular Cell 5:6, pages 939-948.
Crossref
Carolyn M Klinge. (2000) Estrogen receptor interaction with co-activators and co-repressors☆. Steroids 65:5, pages 227-251.
Crossref
Christophe Rachez & Leonard P. Freedman. (2000) Mechanisms of gene regulation by vitamin D3 receptor: a network of coactivator interactions. Gene 246:1-2, pages 9-21.
Crossref
Shunzo Kobayashi, Yukashi Ito, Yoshiaki Ando, Yoko Omoto, Tatsuya Toyama & Hirotaka Iwase. (2000) Comparison of five different antibodies in the immunohistochemical assay of estrogen receptor α in Human breast cancer. Breast Cancer 7:2, pages 136-141.
Crossref
Christopher Leo, Hui Li & J.Don Chen. (2000) Differential Mechanisms of Nuclear Receptor Regulation by Receptor-associated Coactivator 3. Journal of Biological Chemistry 275:8, pages 5976-5982.
Crossref
Maurice Needham, Stephanie Raines, Jane McPheat, Clare Stacey, Jonathan Ellston, Susan Hoare & Malcolm Parker. (2000) Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif. The Journal of Steroid Biochemistry and Molecular Biology 72:1-2, pages 35-46.
Crossref
Venkatesh Krishnan, Hunter Heath & Henry U. Bryant. 2000. 123 147 .
M. Parker & C. Bevan. 2000. Testis, Epididymis and Technologies in the Year 2000. Testis, Epididymis and Technologies in the Year 2000 165 172 .
Sandrine Thénot, Sandrine Bonnet, Abdelhay Boulahtouf, Emmanuel Margeat, Catherine A. Royer, Jean-Louis Borgna & Vincent Cavaillès. (1999) Effect of Ligand and DNA Binding on the Interaction between Human Transcription Intermediary Factor 1α and Estrogen Receptors. Molecular Endocrinology 13:12, pages 2137-2150.
Crossref
Charlotte Bevan & Malcolm Parker. (1999) The Role of Coactivators in Steroid Hormone Action. Experimental Cell Research 253:2, pages 349-356.
Crossref
Arvin C. Gee, Kathryn E. Carlson, Paolo G. V. Martini, Benita S. Katzenellenbogen & John A. Katzenellenbogen. (1999) Coactivator Peptides Have a Differential Stabilizing Effect on the Binding of Estrogens and Antiestrogens with the Estrogen Receptor. Molecular Endocrinology 13:11, pages 1912-1923.
Crossref
Xiao Hu & Mitchell A. Lazar. (1999) The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature 402:6757, pages 93-96.
Crossref
Martin K Oehler. (2016) Mechanism of Action of Steroid Hormone Receptors in the Endometrium. British Menopause Society Journal 5:3, pages 103-109.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.