Advanced search
Publication Cover
Molecular and Cellular Biology Volume 19, 1999 - Issue 6
Submit an article Journal homepage
17
Views
40
CrossRef citations to date
0
Altmetric
Gene Expression

Regulation of AUF1 Expression via Conserved Alternatively Spliced Elements in the 3′ Untranslated Region

Gerald M. WilsonDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
,
Yue SunDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
,
Jeremy SellersDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
,
Haiping LuDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
,
Nameeta PenkarDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
,
Gwynn DillardDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157
&
Gary BrewerDepartment of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina27157Correspondence[email protected]
 show all
Pages 4056-4064 | Received 02 Dec 1998, Accepted 11 Mar 1999, Published online: 27 Mar 2023

Citations (40)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Rudolf Pullmann$suffix/text()$suffix/text(), Hyeon Ho Kim, Kotb Abdelmohsen, Ashish Lal, Jennifer L. Martindale, Xiaoling Yang & Myriam Gorospe. (2007) Analysis of Turnover and Translation Regulatory RNA-Binding Protein Expression through Binding to Cognate mRNAs. Molecular and Cellular Biology 27:18, pages 6265-6278.
Read now
Lili Banihashemi, Gerald M. Wilson, Neha Das & Gary Brewer. (2006) Upf1/Upf2 Regulation of 3′ Untranslated Region Splice Variants of AUF1 Links Nonsense-Mediated and A+U-Rich Element-Mediated mRNA Decay. Molecular and Cellular Biology 26:23, pages 8743-8754.
Read now
Jürgen Wittmann, Elly M. Hol & Hans-Martin Jäck. (2006) hUPF2 Silencing Identifies Physiologic Substrates of Mammalian Nonsense-Mediated mRNA Decay. Molecular and Cellular Biology 26:4, pages 1272-1287.
Read now
El-Sayed Akool, Hartmut Kleinert, Farid M. A. Hamada, Mohamed H. Abdelwahab, Ulrich Fürstermann, Josef Pfeilschifter & Wolfgang Eberhardt. (2003) Nitric Oxide Increases the Decay of Matrix Metalloproteinase 9 mRNA by Inhibiting the Expression of mRNA-Stabilizing Factor HuR. Molecular and Cellular Biology 23:14, pages 4901-4916.
Read now
Shankung Lin, Wengong Wang, Gerald M. Wilson, Xiaoling Yang, Gary Brewer, Nikki J. Holbrook & Myriam Gorospe. (2000) Down-Regulation of Cyclin D1 Expression by Prostaglandin A2 Is Mediated by Enhanced Cyclin D1 mRNA Turnover. Molecular and Cellular Biology 20:21, pages 7903-7913.
Read now

Articles from other publishers (35)

Dawon Hong & Sunjoo Jeong. (2023) 3’UTR Diversity: Expanding Repertoire of RNA Alterations in Human mRNAs. Molecules and Cells 46:1, pages 48-56.
Crossref
Emma L. Scotter, Maize C. Cao, Deidre Jansson, Justin Rustenhoven, Leon C.D. Smyth, Miranda C. Aalderink, Andrew Siemens, Vicky Fan, Jane Wu, Edward W. Mee, Richard L.M. Faull & Mike Dragunow. (2022) The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes. Molecular and Cellular Neuroscience 123, pages 103768.
Crossref
Jia Jia Chan, Hossein Tabatabaeian & Yvonne Tay. (2022) 3′UTR heterogeneity and cancer progression. Trends in Cell Biology.
Crossref
May T. Aung-Htut, Iain Comerford, Russell Johnsen, Kerrie Foyle, Sue Fletcher & Steve D. Wilton. (2019) Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides. Scientific Reports 9:1.
Crossref
E. N. Filatova & O. V. Utkin. (2018) The Role of Noncoding mRNA Isoforms in the Regulation of Gene Expression. Russian Journal of Genetics 54:8, pages 879-887.
Crossref
Katrin Kemmerer, Sandra Fischer & Julia E. Weigand. (2018) Auto- and cross-regulation of the hnRNPs D and DL. RNA 24:3, pages 324-331.
Crossref
Kaitlin Weskamp & Sami J. Barmada. 2018. RNA Metabolism in Neurodegenerative Diseases. RNA Metabolism in Neurodegenerative Diseases 103 142 .
Andrew Nickless, Julie M. Bailis & Zhongsheng You. (2017) Control of gene expression through the nonsense-mediated RNA decay pathway. Cell & Bioscience 7:1.
Crossref
Matteo Lunghi, Furio Spano, Alessandro Magini, Carla Emiliani, Vern B. Carruthers & Manlio Di Cristina. (2015) Alternative splicing mechanisms orchestrating post-transcriptional gene expression: intron retention and the intron-rich genome of apicomplexan parasites. Current Genetics 62:1, pages 31-38.
Crossref
Tomasz Herjan, Peng Yao, Wen Qian, Xiao Li, Caini Liu, Katarzyna Bulek, Dongxu Sun, Wen-Pin Yang, Jun Zhu, Aiqing He, Julie A. Carman, Serpil C. Erzurum, Howard D. Lipshitz, Paul L. Fox, Thomas A. Hamilton & Xiaoxia Li. (2013) HuR Is Required for IL-17–Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization. The Journal of Immunology 191:2, pages 640-649.
Crossref
Elizabeth J.F. White, Gary Brewer & Gerald M. Wilson. (2013) Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:6-7, pages 680-688.
Crossref
Y. Sun, Y. Fu, Y. Li & A. Xu. (2012) Genome-wide alternative polyadenylation in animals: insights from high-throughput technologies. Journal of Molecular Cell Biology 4:6, pages 352-361.
Crossref
Caroline Serrano-Nascimento, Jamile Calil-Silveira, Francemilson Goulart-Silva & Maria Tereza Nunes. (2012) New insights about the posttranscriptional mechanisms triggered by iodide excess on sodium/iodide symporter (NIS) expression in PCCl3 cells. Molecular and Cellular Endocrinology 349:2, pages 154-161.
Crossref
Frances M. Gratacós & Gary Brewer. (2010) The role of AUF1 in regulated mRNA decay. Wiley Interdisciplinary Reviews: RNA 1:3, pages 457-473.
Crossref
Nancy H. Ing. (2010) Estradiol up-regulates expression of the A+U-rich binding factor 1 (AUF1) gene in the sheep uterus. The Journal of Steroid Biochemistry and Molecular Biology 122:4, pages 172-179.
Crossref
Caroline Serrano-Nascimento, Jamile Calil-Silveira & Maria Tereza Nunes. (2010) Posttranscriptional regulation of sodium-iodide symporter mRNA expression in the rat thyroid gland by acute iodide administration. American Journal of Physiology-Cell Physiology 298:4, pages C893-C899.
Crossref
Nicholas J. McGlincy & Christopher W.J. Smith. (2008) Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?. Trends in Biochemical Sciences 33:8, pages 385-393.
Crossref
Audrey McAlinden, Brian Johnstone, John Kollar, Najam Kazmi & Thomas M. Hering. (2008) Expression of two novel alternatively spliced COL2A1 isoforms during chondrocyte differentiation. Matrix Biology 27:3, pages 254-266.
Crossref
Daniel H. Lackner & Jürg Bähler. 2008. 199 251 .
Liana F. Lareau, Angela N. Brooks, David A. W. Soergel, Qi Meng & Steven E. Brenner. 2007. Alternative Splicing in the Postgenomic Era. Alternative Splicing in the Postgenomic Era 190 211 .
Bhabadeb Chowdhury, Sandeep Krishnan, Christos G. Tsokos, James W. Robertson, Carolyn U. Fisher, Madhusoodana P. Nambiar & George C. Tsokos. (2006) Stability and Translation of TCR ζ mRNA Are Regulated by the Adenosine-Uridine-Rich Elements in Splice-Deleted 3′ Untranslated Region of ζ-Chain. The Journal of Immunology 177:11, pages 8248-8257.
Crossref
Christine M. Misquitta, Tao Chen & Ashok K. Grover. (2006) Control of protein expression through mRNA stability in calcium signalling. Cell Calcium 40:4, pages 329-346.
Crossref
Andrea Thiele, Yoshikuni Nagamine, Sunna Hauschildt & Hans Clevers. (2006) AU-rich elements and alternative splicing in the β-catenin 3′UTR can influence the human β-catenin mRNA stability. Experimental Cell Research 312:12, pages 2367-2378.
Crossref
Bhabadeb Chowdhury, Christos G. Tsokos, Sandeep Krishnan, James Robertson, Carolyn U. Fisher, Rahul G. Warke, Vishal G. Warke, Madhusoodana P. Nambiar & George C. Tsokos. (2005) Decreased Stability and Translation of T Cell Receptor ζ mRNA with an Alternatively Spliced 3′-Untranslated Region Contribute to ζ Chain Down-regulation in Patients with Systemic Lupus Erythematosus. Journal of Biological Chemistry 280:19, pages 18959-18966.
Crossref
Liana F Lareau, Richard E Green, Rajiv S Bhatnagar & Steven E Brenner. (2004) The evolving roles of alternative splicing. Current Opinion in Structural Biology 14:3, pages 273-282.
Crossref
J-J. Hoarau, M. Cesari, H. Caillens, F. Cadet & M. Pabion. (2004) HLA DQA1 genes generate multiple transcripts by alternative splicing and polyadenylation of the 3' untranslated region. Tissue Antigens 63:1, pages 58-71.
Crossref
Bicheng Zhang, Xinmin Nie, Bingyi Xiao, Juanjuan Xiang, Shourong Shen, Jialei Gong, Ming Zhou, Shiguo Zhu, Jie Zhou, Jun Qian, Hongbin Lu, Xianfeng He, Xiaoling Li, Gengxi Hu & Guiyuan Li. (2003) Identification of tissue-specific genes in nasopharyngeal epithelial tissue and differentially expressed genes in nasopharyngeal carcinoma by suppression subtractive hybridization and cDNA microarray. Genes, Chromosomes and Cancer 38:1, pages 80-90.
Crossref
Gerald M. Wilson, Jiebo Lu, Kristina Sutphen, Yue Sun, Yung Huynh & Gary Brewer. (2003) Regulation of A + U-rich Element-directed mRNA Turnover Involving Reversible Phosphorylation of AUF1. Journal of Biological Chemistry 278:35, pages 33029-33038.
Crossref
Myriam Gorospe. 2003. Handbook of Cell Signaling. Handbook of Cell Signaling 283 290 .
Christine M. Misquitta, James Mwanjewe, Lin Nie & Ashok K. Grover. (2002) Sarcoplasmic reticulum Ca 2+ pump mRNA stability in cardiac and smooth muscle: role of the 3′-untranslated region . American Journal of Physiology-Cell Physiology 283:2, pages C560-C568.
Crossref
Charles E. Chalfant, Kristin Rathman, Ryan L. Pinkerman, Rachel E. Wood, Lina M. Obeid, Besim Ogretmen & Yusuf A. Hannun. (2002) De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells. Journal of Biological Chemistry 277:15, pages 12587-12595.
Crossref
Lowell G. Sheflin, Wan Zhang & Stephen W. Spaulding. (2001) Androgen Regulates the Level and Subcellular Distribution of the AU-Rich Ribonucleic Acid-Binding Protein HuR Both in Vitroand in Vivo*. Endocrinology 142:6, pages 2361-2368.
Crossref
Angela J Di Benedetto, Jennifer Klick Stoddard & Bradford J Glavan. (2001) Cloning and molecular characterization of a novel gene encoding a WD-repeat protein expressed in restricted areas of adult rat brain. Gene 271:1, pages 21-31.
Crossref
H.B Rasmussen, M.A Kelly & J Clausen. (2001) Genetic susceptibility to multiple sclerosis: detection of polymorphic nucleotides and an intron in the 3′ untranslated region of the major histocompatibility complex class II transactivator gene. Human Immunology 62:4, pages 371-377.
Crossref
Victor L. Ruiz-Perez, Susan E. Ide, Tim M. Strom, Bettina Lorenz, David Wilson, Kathryn Woods, Lynn King, Clair Francomano, Peter Freisinger, Stephanie Spranger, Bruno Marino, Bruno Dallapiccola, Michael Wright, Thomas Meitinger, Mihael H. Polymeropoulos & Judith Goodship. (2000) Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis. Nature Genetics 24:3, pages 283-286.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.