Advanced search
Publication Cover
Molecular and Cellular Biology Volume 20, 2000 - Issue 1
Submit an article Journal homepage
8
Views
34
CrossRef citations to date
0
Altmetric
DNA Dynamics and Chromosome Structure

A Double-Strand Break in a Chromosomal LINE Element Can Be Repaired by Gene Conversion with Various Endogenous LINE Elements in Mouse Cells

Annie Tremblay1 Molecular Biology Program
,
Maria Jasin2 Cell Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center and Cornell University Graduate School of Medical Sciences, New York, New York
&
Pierre Chartrand1 Molecular Biology Program;3 Department of Pathology and Cellular Biology, University of Montreal, Montreal, Quebec, CanadaCorrespondence[email protected]
Pages 54-60 | Received 21 Jul 1999, Accepted 27 Sep 1999, Published online: 28 Mar 2023

Citations (34)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Ezra Schildkraut, Cheryl A. Miller & Jac A. Nickoloff. (2006) Transcription of a Donor Enhances Its Use during Double-Strand Break-Induced Gene Conversion in Human Cells. Molecular and Cellular Biology 26:8, pages 3098-3105.
Read now

Articles from other publishers (33)

Terrence Hanscom & Mitch McVey. (2020) Regulation of Error-Prone DNA Double-Strand Break Repair and Its Impact on Genome Evolution. Cells 9:7, pages 1657.
Crossref
Chayanin Tangsuwansri, Thanit Saeliw, Surangrat Thongkorn, Weerasak Chonchaiya, Kanya Suphapeetiporn, Apiwat Mutirangura, Tewin Tencomnao, Valerie Wailin Hu & Tewarit Sarachana. (2018) Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses. PLOS ONE 13:7, pages e0201071.
Crossref
Sridaran Dhivya & Kumpati Premkumar. (2016) Nomadic genetic elements contribute to oncogenic translocations: Implications in carcinogenesis. Critical Reviews in Oncology/Hematology 98, pages 81-93.
Crossref
Christopher P. Allen, Akira Fujimori, Ryuichi Okayasu & Jac A. Nickoloff. 2013. Stress-Induced Mutagenesis. Stress-Induced Mutagenesis 183 198 .
Kohei Kurosawa & Kunihiro Ohta. (2011) Genetic Diversification by Somatic Gene Conversion. Genes 2:1, pages 48-58.
Crossref
Margaret L. Hoang, Frederick J. Tan, David C. Lai, Sue E. Celniker, Roger A. Hoskins, Maitreya J. Dunham, Yixian Zheng & Douglas Koshland. (2010) Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination. PLoS Genetics 6:12, pages e1001228.
Crossref
Mariko Sasaki, Julian Lange & Scott Keeney. (2010) Genome destabilization by homologous recombination in the germ line. Nature Reviews Molecular Cell Biology 11:3, pages 182-195.
Crossref
Sebastian Szpakowski, Xueguang Sun, José M. Lage, Andrew Dyer, Jill Rubinstein, Diane Kowalski, Clarence Sasaki, Jose Costa & Paul M. Lizardi. (2009) Loss of epigenetic silencing in tumors preferentially affects primate-specific retroelements. Gene 448:2, pages 151-167.
Crossref
W. Pornthanakasem, N. Kongruttanachok, C. Phuangphairoj, C. Suyarnsestakorn, T. Sanghangthum, S. Oonsiri, W. Ponyeam, T. Thanasupawat, O. Matangkasombut & A. Mutirangura. (2008) LINE-1 methylation status of endogenous DNA double-strand breaks. Nucleic Acids Research 36:11, pages 3667-3675.
Crossref
Adi Barzel & Martin Kupiec. (2008) Finding a match: how do homologous sequences get together for recombination?. Nature Reviews Genetics 9:1, pages 27-37.
Crossref
Sarah A. Maas, Lura Brianna Caddle & Kevin D. Mills. 2008. Mouse Models of Human Blood Cancers. Mouse Models of Human Blood Cancers 81 120 .
Jian-Min Chen, David N. Cooper, Nadia Chuzhanova, Claude Férec & George P. Patrinos. (2007) Gene conversion: mechanisms, evolution and human disease. Nature Reviews Genetics 8:10, pages 762-775.
Crossref
Kenneth S. Ramos, Qiang He, Ted Kalbfleisch, Diego E. Montoya-Durango, Ivo Teneng, Vilius Stribinskis & Marcel Brun. (2007) Computational and biological inference of gene regulatory networks of the LINE-1 retrotransposon. Genomics 90:2, pages 176-185.
Crossref
John V. Moran & Nicolas Gilbert. 2007. Mobile DNA II. Mobile DNA II 836 869 .
Shurjo K. Sen, Charles T. Huang, Kyudong Han & Mark A. Batzer. (2007) Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome. Nucleic Acids Research 35:11, pages 3741-3751.
Crossref
D.J. Hedges & P.L. Deininger. (2007) Inviting instability: Transposable elements, double-strand breaks, and the maintenance of genome integrity. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 616:1-2, pages 46-59.
Crossref
Vilius Stribinskis & Kenneth S. Ramos. (2006) Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo( a )pyrene, an Ubiquitous Environmental Carcinogen . Cancer Research 66:5, pages 2616-2620.
Crossref
Amy E. Hulme, Deanna A. Kulpa, José Luis Garcia Perez & John V. Moran. 2006. Genomic Disorders. Genomic Disorders 35 55 .
Natalay Kouprina, Adam Pavlicek, Vladimir N. Noskov, Greg Solomon, John Otstot, William Isaacs, John D. Carpten, Jeffrey M. Trent, Joanna Schleutker, J. Carl Barrett, Jerzy Jurka & Vladimir Larionov. (2005) Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27 . Genome Research 15:11, pages 1477-1486.
Crossref
Christine Richardson, Jeremy M Stark, Melissa Ommundsen & Maria Jasin. (2004) Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene 23:2, pages 546-553.
Crossref
Hélène D'Anjou, Catherine Chabot & Pierre Chartrand. (2004) Preferential accessibility to specific genomic loci for the repair of double-strand breaks in human cells. Nucleic Acids Research 32:20, pages 6136-6143.
Crossref
Prescott L Deininger, John V Moran, Mark A Batzer & Haig H KazazianJrJr. (2003) Mobile elements and mammalian genome evolution. Current Opinion in Genetics & Development 13:6, pages 651-658.
Crossref
H Würtele, K C E Little & P Chartrand. (2003) Illegitimate DNA integration in mammalian cells. Gene Therapy 10:21, pages 1791-1799.
Crossref
Kim P. Lu & Kenneth S. Ramos. (2003) Redox Regulation of a Novel L1Md-A2 Retrotransposon in Vascular Smooth Muscle Cells. Journal of Biological Chemistry 278:30, pages 28201-28209.
Crossref
Shigeru Sasaki, Yukiko Kitagawa, Yoshitaka Sekido, John D Minna, Hiroyuki Kuwano, Jun Yokota & Takashi Kohno. (2003) Molecular processes of chromosome 9p21 deletions in human cancers. Oncogene 22:24, pages 3792-3798.
Crossref
Matthew E Hurles. 2001. eLS. eLS.
Masamitsu Honma, Masako Izumi, Mayumi Sakuraba, Satoshi Tadokoro, Hiroko Sakamoto, Wensheng Wang, Fumio Yatagai & Makoto Hayashi. (2003) Deletion, rearrangement, and gene conversion; genetic consequences of chromosomal double-strand breaks in human cells. Environmental and Molecular Mutagenesis 42:4, pages 288-298.
Crossref
RICHARD v. STERNBERG. (2006) On the Roles of Repetitive DNA Elements in the Context of a Unified Genomic-Epigenetic System. Annals of the New York Academy of Sciences 981:1, pages 154-188.
Crossref
Prescott L. Deininger & Mark A. Batzer. (2002) Mammalian Retroelements. Genome Research 12:10, pages 1455-1465.
Crossref
Jeremy S. Myers, Bethaney J. Vincent, Hunt Udall, W. Scott Watkins, Tammy A. Morrish, Gail E. Kilroy, Gary D. Swergold, Jurgen Henke, Lotte Henke, John V. Moran, Lynn B. Jorde & Mark A. Batzer. (2002) A Comprehensive Analysis of Recently Integrated Human Ta L1 Elements. The American Journal of Human Genetics 71:2, pages 312-326.
Crossref
Guiyun Yan & Henk Braig. 2001. Genetically Engineered Organisms. Genetically Engineered Organisms 251 314 .
Yunfu Lin & Alan S Waldman. (2001) Capture of DNA Sequences at Double-Strand Breaks in Mammalian Chromosomes. Genetics 158:4, pages 1665-1674.
Crossref
David M. Noll, Anne M. Noronha & Paul S. Miller. (2001) Synthesis and Characterization of DNA Duplexes Containing an N 4 C−Ethyl−N 4 C Interstrand Cross-Link . Journal of the American Chemical Society 123:15, pages 3405-3411.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.