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Nucleocytoplasmic Communication

Neoplastic Transformation by Notch Requires Nuclear Localization

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Pages 3928-3941 | Received 28 Dec 1999, Accepted 08 Mar 2000, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

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Rodrigo Vasquez-Del Carpio, Fred M. Kaplan, Kelly L. Weaver, Jeffrey D. VanWye, Marie-Clotilde Alves-Guerra, David J. Robbins & Anthony J. Capobianco. (2011) Assembly of a Notch Transcriptional Activation Complex Requires Multimerization. Molecular and Cellular Biology 31:7, pages 1396-1408.
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Jing Wu & Emery H. Bresnick. (2007) Glucocorticoid and Growth Factor Synergism Requirement for Notch4 Chromatin Domain Activation. Molecular and Cellular Biology 27:6, pages 2411-2422.
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Alexis Dumortier, Robin Jeannet, Peggy Kirstetter, Eva Kleinmann, MacLean Sellars, Nuno R. dos Santos, Christelle Thibault, Jochen Barths, Jacques Ghysdael, Jennifer A. Punt, Philippe Kastner & Susan Chan. (2006) Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice. Molecular and Cellular Biology 26:1, pages 209-220.
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Andrew P. Weng, Yunsun Nam, Michael S. Wolfe, Warren S. Pear, James D. Griffin, Stephen C. Blacklow & Jon C. Aster. (2003) Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling. Molecular and Cellular Biology 23:2, pages 655-664.
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Shawn Jeffries, David J. Robbins & Anthony J. Capobianco. (2002) Characterization of a High-Molecular-Weight Notch Complex in the Nucleus of Notchic-Transformed RKE Cells and in a Human T-Cell Leukemia Cell Line. Molecular and Cellular Biology 22:11, pages 3927-3941.
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Virote Sriuranpong, Michael W. Borges, Christopher L. Strock, Eric K. Nakakura, D. Neil Watkins, Christine M. Blaumueller, Barry D. Nelkin & Douglas W. Ball. (2002) Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1. Molecular and Cellular Biology 22:9, pages 3129-3139.
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Franz Oswald, Birgitt Täuber, Thomas Dobner, Soizic Bourteele, Ulrike Kostezka, Guido Adler, Susanne Liptay & Roland M. Schmid. (2001) p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1. Molecular and Cellular Biology 21:22, pages 7761-7774.
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Chiara Ronchini & Anthony J. Capobianco. (2001) Induction of Cyclin D1 Transcription and CDK2 Activity by Notchic: Implication for Cell Cycle Disruption in Transformation by Notchic. Molecular and Cellular Biology 21:17, pages 5925-5934.
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Jon C. Aster, Lanwei Xu, Fredrick G. Karnell, Vytas Patriub, John C. Pui & Warren S. Pear. (2000) Essential Roles for Ankyrin Repeat and Transactivation Domains in Induction of T-Cell Leukemia by Notch1. Molecular and Cellular Biology 20:20, pages 7505-7515.
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