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Molecular and Cellular Biology Volume 20, 2000 - Issue 12
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Cell Growth and Development

Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene ngn3

Patrick Jacquemin1 Hormone and Metabolic Research Unit, Université catholique de Louvain and Christian de Duve Institute of Cellular Pathology
,
Serge M. Durviaux1 Hormone and Metabolic Research Unit, Université catholique de Louvain and Christian de Duve Institute of Cellular Pathology
,
Jan Jensen2 Department of Developmental Biology, Hagedorn Research Institute, 2820Gentofte, Denmark
,
Catherine Godfraind3 Department of Pathology, Université catholique de Louvain, 1200Brussels
,
Gerard Gradwohl4 Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM, Université Louis Pasteur, 67404Illkirch Cedex, C. U. Strasbourg, France
,
François Guillemot4 Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM, Université Louis Pasteur, 67404Illkirch Cedex, C. U. Strasbourg, France
,
Ole D. Madsen2 Department of Developmental Biology, Hagedorn Research Institute, 2820Gentofte, Denmark
,
Peter Carmeliet5 Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, 3000Leuven, Belgium
,
Mieke Dewerchin5 Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, 3000Leuven, Belgium
,
Désiré Collen5 Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, 3000Leuven, Belgium
,
Guy G. Rousseau1 Hormone and Metabolic Research Unit, Université catholique de Louvain and Christian de Duve Institute of Cellular Pathology
&
Frédéric P. Lemaigre1 Hormone and Metabolic Research Unit, Université catholique de Louvain and Christian de Duve Institute of Cellular PathologyCorrespondence[email protected]
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Pages 4445-4454 | Received 04 Oct 1999, Accepted 07 Mar 2000, Published online: 28 Mar 2023

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Reshmi Dassaye, Strini Naidoo & Marlon E. Cerf. (2016) Transcription factor regulation of pancreatic organogenesis, differentiation and maturation. Islets 8:1, pages 13-34.
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Uma Gunasekaran, Courtney W. Hudgens, Brian T. Wright, Matthew F. Maulis & Maureen Gannon. (2012) Differential regulation of embryonic and adult β cell replication. Cell Cycle 11:13, pages 2431-2442.
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Hong Soon Kang, Yong-Sik Kim, Gary ZeRuth, Ju Youn Beak, Kevin Gerrish, Gamze Kilic, Beatriz Sosa-Pineda, Jan Jensen, Julie Foley & Anton M. Jetten. (2009) Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene Expression. Molecular and Cellular Biology 29:24, pages 6366-6379.
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Jean-Bernard Beaudry, Christophe E. Pierreux, Graham P. Hayhurst, Nicolas Plumb-Rudewiez, Mary C. Weiss, Guy G. Rousseau & Frédéric P. Lemaigre. (2006) Threshold Levels of Hepatocyte Nuclear Factor 6 (HNF-6) Acting in Synergy with HNF-4 and PGC-1α Are Required for Time-Specific Gene Expression during Liver Development. Molecular and Cellular Biology 26:16, pages 6037-6046.
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Nir E. Rubins, Joshua R. Friedman, Phillip P. Le, Liping Zhang, John Brestelli & Klaus H. Kaestner. (2005) Transcriptional Networks in the Liver: Hepatocyte Nuclear Factor 6 Function Is Largely Independent of Foxa2. Molecular and Cellular Biology 25:16, pages 7069-7077.
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Francisco M. Rausa, Yongjun Tan & Robert H. Costa. (2003) Association between Hepatocyte Nuclear Factor 6 (HNF-6) and FoxA2 DNA Binding Domains Stimulates FoxA2 Transcriptional Activity but Inhibits HNF-6 DNA Binding. Molecular and Cellular Biology 23:2, pages 437-449.
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