19
Views
67
CrossRef citations to date
0
Altmetric
Gene Expression

Evidence for an Interaction between Ubiquitin-Conjugating Enzymes and the 26S Proteasome

, , , &
Pages 4691-4698 | Received 09 Feb 2000, Accepted 31 Mar 2000, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Matthew I. Hiskens, Anthony G. Schneiders, Mariana Angoa-Pérez, Rebecca K. Vella & Andrew S. Fenning. (2020) Blood biomarkers for assessment of mild traumatic brain injury and chronic traumatic encephalopathy. Biomarkers 25:3, pages 213-227.
Read now
Kevin K. Wang, Zhihui Yang, George Sarkis, Isabel Torres & Vijaya Raghavan. (2017) Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries. Expert Opinion on Therapeutic Targets 21:6, pages 627-638.
Read now
Stefania Mondello, Uwe Muller, Andreas Jeromin, Jackson Streeter, Ronald L Hayes & Kevin KW Wang. (2011) Blood-based diagnostics of traumatic brain injuries. Expert Review of Molecular Diagnostics 11:1, pages 65-78.
Read now
Yoon Park, Yong-Pil Hwang, Jong-Sik Lee, Sang-Hyun Seo, Sungjoo Kim Yoon & Jong-Bok Yoon. (2005) Proteasomal ATPase-Associated Factor 1 Negatively Regulates Proteasome Activity by Interacting with Proteasomal ATPases. Molecular and Cellular Biology 25:9, pages 3842-3853.
Read now
Li Chen & Kiran Madura. (2002) Rad23 Promotes the Targeting of Proteolytic Substrates to the Proteasome. Molecular and Cellular Biology 22:13, pages 4902-4913.
Read now

Articles from other publishers (62)

Jussi P. Posti & Olli Tenovuo. (2022) Blood‐based biomarkers and traumatic brain injury—A clinical perspective. Acta Neurologica Scandinavica 146:4, pages 389-399.
Crossref
Adrian M. Svingos, Steven A. Robicsek, Ronald L. Hayes, Kevin K. Wang, Claudia S. Robertson, Gretchen M. Brophy, Linda Papa, Andrea Gabrielli, H. Julia Hannay, Russell M. Bauer & Shelley C. Heaton. (2022) Predicting Clinical Outcomes 7–10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2. Neurocritical Care 37:1, pages 172-183.
Crossref
Firas Kobeissy, Khalil Mallah, Kazem Zibara, Fatima Dakroub, Zeinab Dalloul, Mohammad Nasser, Leila Nasrallah, Zahraa Mallah, Ghewa A. El-Achkar, Naify Ramadan, Wael Mohamed, Stefania Mondello, Hala Darwish, Eva Hamade & Aida Habib. (2022) The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model. Neurochemistry International 154, pages 105301.
Crossref
Linda Papa. 2022. Tackling the Concussion Epidemic. Tackling the Concussion Epidemic 71 84 .
Stephanie TurnerRachel LazarusDonald MarionKeith L. Main. (2021) Molecular and Diffusion Tensor Imaging Biomarkers of Traumatic Brain Injury: Principles for Investigation and Integration. Journal of Neurotrauma 38:13, pages 1762-1782.
Crossref
V. Sapin, R. Gaulmin, R. Aubin, S. Walrand, A. Coste & M. Abbot. (2021) Blood biomarkers of mild traumatic brain injury: State of art. Neurochirurgie 67:3, pages 249-254.
Crossref
Linda Papa. 2021. Concussions in Athletics. Concussions in Athletics 271 283 .
Damien Bouvier, Charlotte Oris, Marina Brailova, Julie Durif & Vincent Sapin. (2020) Interest of blood biomarkers to predict lesions in medical imaging in the context of mild traumatic brain injury. Clinical Biochemistry 85, pages 5-11.
Crossref
Paymon Garakani RezaiiGerald Arthur GrantMichael Maroun ZeinehKara Janice RichardsonMaria Lynn CoburnAnthony Marco BetArt WeberBin JiangYing LiKristine UbungenGay RouthAlex Marie WheatcroftAmy Davine PaulinoRonald Lawrence HayesGary Kenneth SteinbergMax Wintermark. (2019) Stability of Blood Biomarkers of Traumatic Brain Injury. Journal of Neurotrauma 36:16, pages 2407-2416.
Crossref
Edward J. Goetzl, Fanny M. Elahi, Maja Mustapic, Dimitrios Kapogiannis, Moira Pryhoda, Anah Gilmore, Kimberly A. Gorgens, Bradley Davidson, Anne‐Charlotte Granholm & Aurélie Ledreux. (2019) Altered levels of plasma neuron‐derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury. The FASEB Journal 33:4, pages 5082-5088.
Crossref
Sarah C. Hellewell, Stefania Mondello, Alison Conquest, Gerry Shaw, Irina Madorsky, Jay V. Deng, Lorraine Little, Firas Kobeissy, Nicole Bye, Rinaldo Bellomo, David J. Cooper, Shirley Vallance, Jasmine Board & Maria C. Morganti-Kossmann. (2018) Erythropoietin Does Not Alter Serum Profiles of Neuronal and Axonal Biomarkers After Traumatic Brain Injury. Critical Care Medicine 46:4, pages 554-561.
Crossref
Keisuke Kawata, Ryan Tierney & Dianne Langford. 2018. Sports Neurology. Sports Neurology 217 233 .
Alastair Jones & Paul Jarvis. (2017) Review of the potential use of blood neuro-biomarkers in the diagnosis of mild traumatic brain injury. Clinical and Experimental Emergency Medicine 4:3, pages 121-127.
Crossref
Dorin Harpaz, Evgeni Eltzov, Raymond C.S. Seet, Robert S. Marks & Alfred I.Y. Tok. (2017) Point-of-Care-Testing in Acute Stroke Management: An Unmet Need Ripe for Technological Harvest. Biosensors 7:4, pages 30.
Crossref
Safa Azar, Anwarul Hasan, Richard Younes, Farah Najdi, Lama Baki, Hussein Ghazale, Firas H. Kobeissy, Kazem Zibara & Stefania Mondello. 2017. Neuroproteomics. Neuroproteomics 45 63 .
Linda Papa. (2016) Potential Blood-based Biomarkers for Concussion. Sports Medicine and Arthroscopy Review 24:3, pages 108-115.
Crossref
Francis Wang Dang, Li Chen & Kiran Madura. (2016) Catalytically Active Proteasomes Function Predominantly in the Cytosol. Journal of Biological Chemistry 291:36, pages 18765-18777.
Crossref
Xian-jian HuangOlena GlushakovaStefania MondelloKen VanRonald L. HayesBruce G. Lyeth. (2015) Acute Temporal Profiles of Serum Levels of UCH-L1 and GFAP and Relationships to Neuronal and Astroglial Pathology following Traumatic Brain Injury in Rats. Journal of Neurotrauma 32:16, pages 1179-1189.
Crossref
Linda PapaMichelle M. RamiaDamyan EdwardsBrian D. JohnsonSemyon M. Slobounov. (2015) Systematic Review of Clinical Studies Examining Biomarkers of Brain Injury in Athletes after Sports-Related Concussion. Journal of Neurotrauma 32:10, pages 661-673.
Crossref
Shoji Yokobori, Zhiqun Zhang, Ahmed Moghieb, Stefania Mondello, Shyam Gajavelli, W. Dalton Dietrich, Helen Bramlett, Ronald L. Hayes, Michael Wang, Kevin K.W. Wang & M. Ross Bullock. (2015) Acute Diagnostic Biomarkers for Spinal Cord Injury: Review of the Literature and Preliminary Research Report. World Neurosurgery 83:5, pages 867-878.
Crossref
Stefania Mondello & Ronald L. Hayes. 2015. Traumatic Brain Injury, Part I. Traumatic Brain Injury, Part I 245 265 .
Frederick G. Strathmann, Stefanie Schulte, Kyle Goerl & David J. Petron. (2014) Blood-based biomarkers for traumatic brain injury: Evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory perspectives. Clinical Biochemistry 47:10-11, pages 876-888.
Crossref
Ségolène Mrozek, Julien Dumurgier, Giuseppe Citerio, Alexandre Mebazaa & Thomas Geeraerts. (2014) Biomarkers and acute brain injuries: interest and limits. Critical Care 18:2, pages 220.
Crossref
Linda Papa. 2014. Concussions in Athletics. Concussions in Athletics 235 248 .
Olena Glushakova, Stefania Mondello & Ronald L. Hayes. 2014. Vascular Mechanisms in CNS Trauma. Vascular Mechanisms in CNS Trauma 303 331 .
Shoji Yokobori, Khadil Hosein, Stephen Burks, Ishna Sharma, Shyam Gajavelli & Ross Bullock. (2013) Biomarkers for the Clinical Differential Diagnosis in Traumatic Brain Injury-A Systematic Review. CNS Neuroscience & Therapeutics 19:8, pages 556-565.
Crossref
Rajendra Upadhya, Leona T. Campbell, Maureen J. Donlin, Rajeev Aurora & Jennifer K. Lodge. (2013) Global Transcriptome Profile of Cryptococcus neoformans during Exposure to Hydrogen Peroxide Induced Oxidative Stress. PLoS ONE 8:1, pages e55110.
Crossref
C. Ratna Prabha, Soumya Mukherjee, Renuka Raman & Swapnali Kulkarni. (2012) The ends and means of artificially induced targeted protein degradation. Applied Microbiology and Biotechnology 96:5, pages 1111-1123.
Crossref
Stefania MondelloAndreas JerominAndras BukiRoss BullockEndre CzeiterNoemi KovacsPal BarzoKara SchmidFrank TortellaKevin K. WangRonald L. Hayes. (2012) Glial Neuronal Ratio: A Novel Index for Differentiating Injury Type in Patients with Severe Traumatic Brain Injury. Journal of Neurotrauma 29:6, pages 1096-1104.
Crossref
J.P. Cata, B. Abdelmalak & E. Farag. (2011) Neurological biomarkers in the perioperative period. British Journal of Anaesthesia 107:6, pages 844-858.
Crossref
Gretchen M. BrophyStefania MondelloLinda PapaSteven A. RobicsekAndrea GabrielliJoseph TepasIIIIIIAndras BukiClaudia RobertsonFrank C. TortellaRonald L. HayesKevin K.W. Wang. (2011) Biokinetic Analysis of Ubiquitin C-Terminal Hydrolase-L1 (UCH-L1) in Severe Traumatic Brain Injury Patient Biofluids. Journal of Neurotrauma 28:6, pages 861-870.
Crossref
Pieter E Vos. (2011) Biomarkers of focal and diffuse traumatic brain injury. Critical Care 15:4, pages 183.
Crossref
Stefania Mondello, Linda Papa, Andras Buki, M Ross Bullock, Endre Czeiter, Frank C Tortella, Kevin K Wang & Ronald L Hayes. (2011) Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study. Critical Care 15:3, pages R156.
Crossref
Ming C. Liu, Linnet Akinyi, Dancia Scharf, Jixiang Mo, Stephen F. Larner, Uwe Muller, Monika W. Oli, Wenrong Zheng, Firas Kobeissy, Linda Papa, Xi-Chun Lu, Jitendra R. Dave, Frank C. Tortella, Ronald L. Hayes & Kevin K. W. Wang. (2010) Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats. European Journal of Neuroscience 31:4, pages 722-732.
Crossref
Linda Papa, Linnet Akinyi, Ming Cheng Liu, Jose A. Pineda, Joseph J. TepasIIIIII, Monika W. Oli, Wenrong Zheng, Gillian Robinson, Steven A. Robicsek, Andrea Gabrielli, Shelley C. Heaton, H Julia Hannay, Jason A. Demery, Gretchen M. Brophy, Joe Layon, Claudia S. Robertson, Ronald L. Hayes & Kevin K. W. Wang. (2010) Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury*. Critical Care Medicine 38:1, pages 138-144.
Crossref
Nitza L. Díaz-Blanco & José R. Rodríguez-Medina. (2007) Dosage rescue byUBC4 restores cell wall integrity inSaccharomyces cerevisiae lacking the myosin type II geneMYO1. Yeast 24:4, pages 343-355.
Crossref
Bernat Crosas, John Hanna, Donald S. Kirkpatrick, Dan Phoebe Zhang, Yoshiko Tone, Nathaniel A. Hathaway, Christa Buecker, David S. Leggett, Marion Schmidt, Randall W. King, Steven P. Gygi & Daniel Finley. (2006) Ubiquitin Chains Are Remodeled at the Proteasome by Opposing Ubiquitin Ligase and Deubiquitinating Activities. Cell 127:7, pages 1401-1413.
Crossref
Julie A. Maupin‐Furlow, Matthew A. Humbard, P. Aaron Kirkland, Wei Li, Christopher J. Reuter, Amy J. Wright & G. Zhou. 2006. 125 169 .
Jean E. O'Donoghue & Colin Gordon. 2005. Protein Degradation. Protein Degradation 157 182 .
Show-Mei Chuang & Kiran Madura. (2005) Saccharomyces cerevisiae Ub-Conjugating Enzyme Ubc4 Binds the Proteasome in the Presence of Translationally Damaged Proteins . Genetics 171:4, pages 1477-1484.
Crossref
Michael H. Glickman & Dina Raveh. (2005) Proteasome plasticity. FEBS Letters 579:15, pages 3214-3223.
Crossref
Marlies LÖSCHER, Klaus FORTSCHEGGER, Gustav RITTER, Martina WOSTRY, Regina VOGLAUER, Johannes A. SCHMID, Steven WATTERSA. Jennifer RIVETTPaul AJUHAngus I. LAMONDHermann KATINGER & Johannes GRILLARI. (2005) Interaction of U-box E3 ligase SNEV with PSMB4, the β7 subunit of the 20 S proteasome. Biochemical Journal 388:2, pages 593-603.
Crossref
Rosa Farràs, Guillaume Bossis, Elisabetta Andermarcher, Isabelle Jariel-Encontre & Marc Piechaczyk. (2005) Mechanisms of delivery of ubiquitylated proteins to the proteasome: new target for anti-cancer therapy?. Critical Reviews in Oncology/Hematology 54:1, pages 31-51.
Crossref
Marion Schmidt, John Hanna, Suzanne Elsasser & Daniel Finley. (2005) Proteasome-associated proteins: regulation of a proteolytic machine. Biological Chemistry 386:8.
Crossref
Ting Hu, David P Gibson, Gregory J Carr, Suzanne M Torontali, Jay P Tiesman, Joel G Chaney & Marilyn J Aardema. (2004) Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 549:1-2, pages 5-27.
Crossref
Ian Dawes. 2004. Metabolism and Molecular Physiology of Saccharomyces Cerevisiae, 2nd Edition. Metabolism and Molecular Physiology of Saccharomyces Cerevisiae, 2nd Edition 376 438 .
Maurits F. Kleijnen, Rodolfo M. Alarcón & Peter M. Howley. (2003) The Ubiquitin-associated Domain of hPLIC-2 Interacts with the Proteasome. Molecular Biology of the Cell 14:9, pages 3868-3875.
Crossref
Denise Escalier, Xi-Yuan Bai, Derek Silvius, Pin-Xian Xu & Xin Xu. (2003) Spermatid nuclear and sperm periaxonemal anomalies in the mouseUbe2b null mutant. Molecular Reproduction and Development 65:3, pages 298-308.
Crossref
Jianxin You, Min Wang, Tsutomu Aoki, Taka-aki Tamura & Cecile M. Pickart. (2003) Proteolytic Targeting of Transcriptional Regulator TIP120B by a HECT Domain E3 Ligase. Journal of Biological Chemistry 278:26, pages 23369-23375.
Crossref
Michael Seeger, Rasmus Hartmann-Petersen, Caroline R.M. Wilkinson, Mairi Wallace, Itaru Samejima, Martin S. Taylor & Colin Gordon. (2003) Interaction of the Anaphase-promoting Complex/Cyclosome and Proteasome Protein Complexes with Multiubiquitin Chain-binding Proteins. Journal of Biological Chemistry 278:19, pages 16791-16796.
Crossref
Rasmus Hartmann-Petersen, Michael Seeger & Colin Gordon. (2003) Transferring substrates to the 26S proteasome. Trends in Biochemical Sciences 28:1, pages 26-31.
Crossref
David S. Leggett, John Hanna, Anna Borodovsky, Bernat Crosas, Marion Schmidt, Rohan T. Baker, Thomas Walz, Hidde Ploegh & Daniel Finley. (2002) Multiple Associated Proteins Regulate Proteasome Structure and Function. Molecular Cell 10:3, pages 495-507.
Crossref
Tadashi Suzuki, Hangil Park & William J. Lennarz. (2002) Cytoplasmic peptide: N ‐glycanase (PNGase) in eukaryotic cells: occurrence, primary structure, and potential functions . The FASEB Journal 16:7, pages 635-641.
Crossref
Michael H. Glickman & Aaron Ciechanover. (2002) The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction. Physiological Reviews 82:2, pages 373-428.
Crossref
Kenneth L Rock, Ian A York, Tomo Saric & Alfred L Goldberg. 2002. 1 70 .
H. D. Ulrich. 2002. The Proteasome — Ubiquitin Protein Degradation Pathway. The Proteasome — Ubiquitin Protein Degradation Pathway 137 174 .
M. H. Glickman & V. Maytal. 2002. The Proteasome — Ubiquitin Protein Degradation Pathway. The Proteasome — Ubiquitin Protein Degradation Pathway 43 72 .
Li Chen, Ujwal Shinde, Tatiana G Ortolan & Kiran Madura. (2001) Ubiquitin‐associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi‐ubiquitin chain assembly. EMBO reports 2:10, pages 933-938.
Crossref
Albrecht G. von Arnim. (2001) A Hitchhiker's Guide to the Proteasome. Science's STKE 2001:97.
Crossref
Youming Xie & Alexander Varshavsky. (2001) RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit. Proceedings of the National Academy of Sciences 98:6, pages 3056-3061.
Crossref
Didier Attaix, Lydie Combaret, Marie-Noëlle Pouch & Daniel Taillandier. (2001) Regulation of proteolysis. Current Opinion in Clinical Nutrition and Metabolic Care 4:1, pages 45-49.
Crossref
Jianxin You & Cecile M. Pickart. (2001) A HECT Domain E3 Enzyme Assembles Novel Polyubiquitin Chains. Journal of Biological Chemistry 276:23, pages 19871-19878.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.