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Molecular and Cellular Biology Volume 20, 2000 - Issue 13
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Cell Growth and Development

Cross Talk of pp125FAK and pp59Lyn Non-Receptor Tyrosine Kinases to Insulin-Mimetic Signaling in Adipocytes

Günter MüllerAventis Pharma Deutschland GmbH, 65926Frankfurt am Main, GermanyCorrespondence[email protected]
,
Susanne WiedAventis Pharma Deutschland GmbH, 65926Frankfurt am Main, Germany
&
Wendelin FrickAventis Pharma Deutschland GmbH, 65926Frankfurt am Main, Germany
Pages 4708-4723 | Received 31 Jan 2000, Accepted 12 Apr 2000, Published online: 28 Mar 2023

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Manu Vatish, Eijiro Yamada, Jeffrey E. Pessin & Claire C. Bastie. (2009) Fyn kinase function in lipid utilization: a new upstream regulator of AMPK activity?. Archives of Physiology and Biochemistry 115:4, pages 191-198.
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Nestor Torio‐Padron, Joerg Borges, Arash Momeni, Matthias C. Mueller, Florian T. Tegtmeier & G. Bjoern Stark. (2007) Implantation of VEGF transfected preadipocytes improves vascularization of fibrin implants on the cylinder chorioallantoic membrane (CAM) model. Minimally Invasive Therapy & Allied Technologies 16:3, pages 155-162.
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Günter Müller, Christian Jung, Susanne Wied, Stefan Welte, Holger Jordan & Wendelin Frick. (2001) Redistribution of Glycolipid Raft Domain Components Induces Insulin-Mimetic Signaling in Rat Adipocytes. Molecular and Cellular Biology 21:14, pages 4553-4567.
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Articles from other publishers (31)

Andrew G. Reaume & Christopher A. Lipinski. 2022. Drug Repurposing. Drug Repurposing 196 220 .
Candida J. Rebello, Ann A. Coulter, Andrew G. Reaume, Weina Cong, Luke A. Cusimano & Frank L. Greenway. (2021) MLR-1023 Treatment in Mice and Humans Induces a Thermogenic Program, and Menthol Potentiates the Effect. Pharmaceuticals 14:11, pages 1196.
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Andrew G. Reaume & Christopher A. Lipinski. 2020. Phenotypic Drug Discovery. Phenotypic Drug Discovery 217 232 .
Hong Wang, Alexander K. Diaz, Timothy I. Shaw, Yuxin Li, Mingming Niu, Ji-Hoon Cho, Barbara S. Paugh, Yang Zhang, Jeffrey Sifford, Bing Bai, Zhiping Wu, Haiyan Tan, Suiping Zhou, Laura D. Hover, Heather S. Tillman, Abbas Shirinifard, Suresh Thiagarajan, Andras Sablauer, Vishwajeeth Pagala, Anthony A. High, Xusheng Wang, Chunliang Li, Suzanne J. Baker & Junmin Peng. (2019) Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes. Nature Communications 10:1.
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Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe & Steven N. Hochwald. (2019) Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase Signaling. Cellular and Molecular Gastroenterology and Hepatology 8:1, pages 37-60.
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J Zhang, Q Gao, Y Zhou, U Dier, N Hempel & S N Hochwald. (2015) Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis. Oncogene 35:15, pages 1926-1942.
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Günter Müller. 2016. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 2681 2722 .
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Kazuhiko Tagawa, Hidenori Homma, Ayumu Saito, Kyota Fujita, Xigui Chen, Seiya Imoto, Tsutomu Oka, Hikaru Ito, Kazumi Motoki, Chisato Yoshida, Hiroyuki Hatsuta, Shigeo Murayama, Takeshi Iwatsubo, Satoru Miyano & Hitoshi Okazawa. (2015) Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain. Human Molecular Genetics 24:2, pages 540-558.
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Günter Müller. 2014. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 1 45 .
Günter Müller. 2014. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 1 100 .
Sandra W Cowan-JacobWolfgang Jahnke & Stefan Knapp. (2014) Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases. Future Medicinal Chemistry 6:5, pages 541-561.
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Junhui Chen, Yuhuan Meng, Jinghui Zhou, Min Zhuo, Fei Ling, Yu Zhang, Hongli Du & Xiaoning Wang. (2013) Identifying Candidate Genes for Type 2 Diabetes Mellitus and Obesity through Gene Expression Profiling in Multiple Tissues or Cells. Journal of Diabetes Research 2013, pages 1-9.
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Alexander R. Ochman, Christopher A. Lipinski, Jeffrey A. Handler, Andrew G. Reaume & Michael S. Saporito. (2012) The Lyn Kinase Activator MLR-1023 Is a Novel Insulin Receptor Potentiator that Elicits a Rapid-Onset and Durable Improvement in Glucose Homeostasis in Animal Models of Type 2 Diabetes. Journal of Pharmacology and Experimental Therapeutics 342:1, pages 23-32.
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Michael S. Saporito, Alexander R. Ochman, Christopher A. Lipinski, Jeffrey A. Handler & Andrew G. Reaume. (2012) MLR-1023 Is a Potent and Selective Allosteric Activator of Lyn Kinase In Vitro That Improves Glucose Tolerance In Vivo. Journal of Pharmacology and Experimental Therapeutics 342:1, pages 15-22.
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Amit Gupta, Bharti Bisht & Chinmoy Sankar Dey. (2012) Focal adhesion kinase negatively regulates neuronal insulin resistance. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1822:6, pages 1030-1037.
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Joseph Larner, David L. Brautigan & Michael O. Thorner. (2010) D-Chiro-Inositol Glycans in Insulin Signaling and Insulin Resistance. Molecular Medicine 16:11-12, pages 543-552.
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Jing-Jing Li & Dong Xie. (2007) Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation. Biochemical and Biophysical Research Communications 357:3, pages 648-654.
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B. Bisht, H. L. Goel & C. S. Dey. (2007) Focal adhesion kinase regulates insulin resistance in skeletal muscle. Diabetologia 50:5, pages 1058-1069.
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L. Goutzanis, E. Vairaktaris, C. Yapijakis, N. Kavantzas, E. Nkenke, S. Derka, S. Vassiliou, Y. Acil, P. Kessler, N. Stavrianeas, D. Perrea, I. Donta, P. Skandalakis & E. Patsouris. (2007) Diabetes may increase risk for oral cancer through the insulin receptor substrate-1 and focal adhesion kinase pathway. Oral Oncology 43:2, pages 165-173.
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Hans Gerhard Vogel. 2008. Drug Discovery and Evaluation. Drug Discovery and Evaluation 1323 1607 .
Makoto Funaki, Lesley DiFransico & Paul A. Janmey. (2006) PI 4,5-P2 stimulates glucose transport activity of GLUT4 in the plasma membrane of 3T3-L1 adipocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1763:8, pages 889-899.
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Günter Müller, Andrea Schulz, Susanne Wied & Wendelin Frick. (2005) Regulation of lipid raft proteins by glimepiride- and insulin-induced glycosylphosphatidylinositol-specific phospholipase C in rat adipocytes. Biochemical Pharmacology 69:5, pages 761-780.
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Günter Müller, Nils Hanekop, Werner Kramer, Wolfhard Bandlow & Wendelin Frick. (2002) Interaction of phosphoinositolglycan(-peptides) with plasma membrane lipid rafts of rat adipocytes. Archives of Biochemistry and Biophysics 408:1, pages 17-32.
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Günter Müller, Christian Jung, Wendelin Frick, Wolfhard Bandlow & Werner Kramer. (2002) Interaction of phosphatidylinositolglycan(-peptides) with plasma membrane lipid rafts triggers insulin-mimetic signaling in rat adipocytes. Archives of Biochemistry and Biophysics 408:1, pages 7-16.
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Günter Müller. (2002) Dynamics of plasma membrane microdomains and cross-talk to the insulin signalling cascade. FEBS Letters 531:1, pages 81-87.
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Christian AnderwaldGünter Müller, Georg KocaClemens FürnsinnWerner WaldhäuslMichael Roden. (2002) Short-Term Leptin-Dependent Inhibition of Hepatic Gluconeogenesis Is Mediated by Insulin Receptor Substrate-2. Molecular Endocrinology 16:7, pages 1612-1628.
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Günter Müller, Nils Hanekop, Susanne Wied & Wendelin Frick. (2002) Cholesterol Depletion Blocks Redistribution of Lipid Raft Components and Insulin-Mimetic Signaling by Glimepiride and Phosphoinositolglycans in Rat Adipocytes. Molecular Medicine 8:3, pages 120-136.
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H. Gerhard Vogel, Wolfgang H. Vogel, Bernward A. Schölkens, Jürgen Sandow, Günter Müller & Wolfgang F. Vogel. 2002. Drug Discovery and Evaluation. Drug Discovery and Evaluation 948 1051 .
Pavel N. Shashkin, Heinrich K. Wasner, Heidi K. Ortmeyer & Barbara C. Hansen. (2001) Prostaglandylinositol cyclic phosphate (cPIP): a novel second messenger of insulin action. Comparative analysis of two kinds of ?insulin mediators?. Diabetes/Metabolism Research and Reviews 17:4, pages 273-284.
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Günter Müller. (2000) The Molecular Mechanism of the Insulin-mimetic/sensitizing Activity of the Antidiabetic Sulfonylurea Drug Amaryl. Molecular Medicine 6:11, pages 907-933.
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