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Cell Growth and Development

Vav2 Activates Rac1, Cdc42, and RhoA Downstream from Growth Factor Receptors but Not β1 Integrins

Betty P. Liu1 Department of Cell Biology and AnatomyCorrespondence[email protected]
&
Keith Burridge1 Department of Cell Biology and Anatomy;2 Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Pages 7160-7169 | Received 22 Feb 2000, Accepted 06 Jul 2000, Published online: 28 Mar 2023

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S R Tie, D J McCarthy, T S Kendrick, A Louw, C Le, J Satiaputra, N Kucera, M Phillips & E Ingley. (2015) Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway. Oncogene 35:16, pages 2098-2111.
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Crossref
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Minghua Zhu, Jianwei Zou, Tieshi Li, Sarah A. O’Brien, Yao Zhang, Sarah Ogden & Weiguo Zhang. (2015) Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function. The Journal of Immunology 195:9, pages 4492-4502.
Crossref
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Crossref
Gunes Uzer, William R. Thompson, Buer Sen, Zhihui Xie, Sherwin S. Yen, Sean Miller, Guniz Bas, Maya Styner, Clinton T. Rubin, Stefan Judex, Keith Burridge & Janet Rubin. (2015) Cell Mechanosensitivity to Extremely Low-Magnitude Signals Is Enabled by a LINCed Nucleus. Stem Cells 33:6, pages 2063-2076.
Crossref
L S Havel, E R Kline, A M Salgueiro & A I Marcus. (2014) Vimentin regulates lung cancer cell adhesion through a VAV2–Rac1 pathway to control focal adhesion kinase activity. Oncogene 34:15, pages 1979-1990.
Crossref
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Crossref
Jennifer Batson, Lucy Maccarthy-Morrogh, Amy Archer, Helen Tanton & Catherine D. Nobes. (2014) EphA receptors regulate prostate cancer cell dissemination through Vav2–RhoA mediated cell–cell repulsion. Biology Open 3:6, pages 453-462.
Crossref
Ludovic Ménard, Peter J. Parker & Stéphanie Kermorgant. (2014) Receptor tyrosine kinase c-Met controls the cytoskeleton from different endosomes via different pathways. Nature Communications 5:1.
Crossref
Ren-Hua Na, Guo-Hui Zhu, Ji-Xuan Luo, Xiao-Jing Meng, Liwang Cui, Hong-Juan Peng, Xiao-guang Chen & Julian Gomez-Cambronero. (2013) Enzymatically active Rho and Rac small-GTPases are involved in the establishment of the vacuolar membrane after Toxoplasma gondii invasion of host cells. BMC Microbiology 13:1.
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William R. Thompson, Christophe Guilluy, Zhihui Xie, Buer Sen, Kaitlyn E. Brobst, Sherwin S. Yen, Gunes Uzer, Maya Styner, Natasha Case, Keith Burridge & Janet Rubin. (2013) Mechanically activated fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells. Stem Cells 31:11, pages 2528-2537.
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Holly Martin, Raghuveer Singh Mali, Peilin Ma, Anindya Chatterjee, Baskar Ramdas, Emily Sims, Veerendra Munugalavadla, Joydeep Ghosh, Ray R. Mattingly, Valeria Visconte, Ramon V. Tiu, Cornelis P. Vlaar, Suranganie Dharmawardhane & Reuben Kapur. (2013) Pak and Rac GTPases promote oncogenic KIT–induced neoplasms. Journal of Clinical Investigation 123:10, pages 4449-4463.
Crossref
Adi D. Dubash, Jennifer L. Koetsier, Evangeline V. Amargo, Nicole A. Najor, Robert M. Harmon & Kathleen J. Green. (2013) The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1. Journal of Cell Biology 202:4, pages 653-666.
Crossref
Matthew C. Jones, Kazuya Machida, Bruce J. Mayer & Christopher E. Turner. (2013) Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration. Molecular Biology of the Cell 24:12, pages 1882-1894.
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Cecilia H. Fernández-Espartero, Damien Ramel, Marganit Farago, Marianne Malartre, Carlos M. Luque, Shiran Limanovich, Shulamit Katzav, Gregory Emery & María D. Martín-Bermudo. (2013) The GEF Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation. Journal of Cell Science.
Crossref
Rosario Espejo, Yowjiun Jeng, Adriana Paulucci-Holthauzen, William Rengifo-Cam, Krysta Honkus, Panos Z. Anastasiadis & Sarita K. Sastry. (2013) PTP-PEST targets a novel tyrosine site in p120-catenin to control epithelial cell motility and Rho GTPase activity. Journal of Cell Science.
Crossref
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Jos van Rijssel, Jeffrey Kroon, Mark Hoogenboezem, Floris P. J. van Alphen, Renske J. de Jong, Elena Kostadinova, Dirk Geerts, Peter L. Hordijk & Jaap D. van Buul. (2012) The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation. Molecular Biology of the Cell 23:15, pages 2831-2844.
Crossref
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Crossref
Kira D. Novakofski, Christopher J. Torre & Lisa A. Fortier. (2012) Interleukin-1α, -6, and -8 decrease Cdc42 activity resulting in loss of articular chondrocyte phenotype. Journal of Orthopaedic Research 30:2, pages 246-251.
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Malgorzata Krause-Gruszczynska, Manja Boehm, Manfred Rohde, Nicole Tegtmeyer, Seiichiro Takahashi, Laszlo Buday, Omar A Oyarzabal & Steffen Backert. (2011) The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2. Cell Communication and Signaling 9:1.
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Crossref
Shashi Kant, Wojciech Swat, Sheng Zhang, Zhong-Yin Zhang, Benjamin G. Neel, Richard A. Flavell & Roger J. Davis. (2011) TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway. Genes & Development 25:19, pages 2069-2078.
Crossref
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K. Stahl, M.N. Mylonakou, Ø. Skare, M. Amiry-Moghaddam & R. Torp. (2011) Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease. Brain Research 1378, pages 105-118.
Crossref
Adi D. Dubash, Christophe Guilluy, Melissa C. Srougi, Etienne Boulter, Keith Burridge & Rafael García-Mata. (2011) The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals. PLoS ONE 6:2, pages e17380.
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Crossref
Sacha B. Geutskens, Peter L. Hordijk & Paula B. van Hennik. (2010) The Chemorepellent Slit3 Promotes Monocyte Migration. The Journal of Immunology 185:12, pages 7691-7698.
Crossref
Di Wu, Akiko Haruta & Qize Wei. (2010) GIPC1 Interacts with MyoGEF and Promotes MDA-MB-231 Breast Cancer Cell Invasion. Journal of Biological Chemistry 285:37, pages 28643-28650.
Crossref
Justin Pahara, Huaiping Shi, Xinmei Chen & Zhixiang Wang. (2010) Dimerization drives PDGF receptor endocytosis through a C-terminal hydrophobic motif shared by EGF receptor. Experimental Cell Research 316:14, pages 2237-2250.
Crossref
Myung-soon Moon & Timothy M. Gomez. (2010) Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivo. Molecular and Cellular Neuroscience 44:2, pages 118-128.
Crossref
Thomas Samson, Christopher Welch, Elizabeth Monaghan-Benson, Klaus M. Hahn & Keith Burridge. (2010) Endogenous RhoG Is Rapidly Activated after Epidermal Growth Factor Stimulation through Multiple Guanine-Nucleotide Exchange Factors. Molecular Biology of the Cell 21:9, pages 1629-1642.
Crossref
S Thalappilly, P Soubeyran, J L Iovanna & N J Dusetti. (2010) VAV2 regulates epidermal growth factor receptor endocytosis and degradation. Oncogene 29:17, pages 2528-2539.
Crossref
Andrés Norambuena, Francisco Palma, M. Inés Poblete, M. Verónica Donoso, Evelyn Pardo, Alfonso González & J. Pablo Huidobro-Toro. (2010) UTP Controls Cell Surface Distribution and Vasomotor Activity of the Human P2Y2 Receptor through an Epidermal Growth Factor Receptor-transregulated Mechanism. Journal of Biological Chemistry 285:5, pages 2940-2950.
Crossref
Lei Duan, Gengsheng Chen, Sumeet Virmani, GuoGuang Ying, Srikumar M. Raja, Byung Min Chung, Mark A. Rainey, Manjari Dimri, Cesar F. Ortega-Cava, Xiangshan Zhao, Robert J. Clubb, Chun Tu, Alagarsamy L. Reddi, Mayumi Naramura, Vimla Band & Hamid Band. (2010) Distinct Roles for Rho Versus Rac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture. Journal of Biological Chemistry 285:2, pages 1555-1568.
Crossref
Qiyu Feng & Richard A. Cerione. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling 1785 1794 .
D Wu, M Asiedu & Q Wei. (2009) Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. Oncogene 28:22, pages 2219-2230.
Crossref
Darci T. Butcher, Tamara Alliston & Valerie M. Weaver. (2009) A tense situation: forcing tumour progression. Nature Reviews Cancer 9:2, pages 108-122.
Crossref
Masayuki Isa, Yusaku Ohta, Shigeyuki Namiki & Kenzo Hirose. (2009) Artificial Control of Subtype-Specific Platelet-Derived Growth Factor–Receptor Signaling. Journal of Pharmacological Sciences 111:3, pages 312-316.
Crossref
Fan YiMin XiaNingjun LiChun ZhangLin TangPin-Lan Li. (2009) Contribution of Guanine Nucleotide Exchange Factor Vav2 to Hyperhomocysteinemic Glomerulosclerosis in Rats. Hypertension 53:1, pages 90-96.
Crossref
P. D. Arora, P. A. Marignani & C. A. McCulloch. (2008) Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2. American Journal of Physiology-Cell Physiology 295:1, pages C130-C137.
Crossref
Stephen Y. Lai, Amy F. Ziober, Megan N. Lee, Noam A. Cohen, Erica M. Falls & Barry L. Ziober. (2008) Activated Vav2 modulates cellular invasion through Rac1 and Cdc42 in oral squamous cell carcinoma. Oral Oncology 44:7, pages 683-688.
Crossref
Mark Schramp, Olivia Ying, Tai Young Kim & G. Steven Martin. (2008) ERK5 promotes Src-induced podosome formation by limiting Rho activation. Journal of Cell Biology 181:7, pages 1195-1210.
Crossref
Tadhg P. BegleyXiaoyang Wu & Jun-Lin Guan. 2007. Wiley Encyclopedia of Chemical Biology. Wiley Encyclopedia of Chemical Biology.
Chang-Xi Bai, Sehyun Kim, Wei-Ping Li, Andrew J Streets, Albert C M Ong & Leonidas Tsiokas. (2008) Activation of TRPP2 through mDia1-dependent voltage gating. The EMBO Journal 27:9, pages 1345-1356.
Crossref
A Colomba, D Courilleau, D Ramel, D D Billadeau, E Espinos, G Delsol, B Payrastre & F Gaits-Iacovoni. (2007) Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas. Oncogene 27:19, pages 2728-2736.
Crossref
Cherilyn A. Elwell, Alhaji Ceesay, Jung Hwa Kim, Daniel Kalman & Joanne N. Engel. (2008) RNA Interference Screen Identifies Abl Kinase and PDGFR Signaling in Chlamydia trachomatis Entry. PLoS Pathogens 4:3, pages e1000021.
Crossref
Inken Wierstra & Jürgen Alves. 2008. 113 333 .
Patrick Ying Kit Yue, Nai Ki Mak, Yuen Kit Cheng, Kar Wah Leung, Tzi Bun Ng, David Tai Ping Fan, Hin Wing Yeung & Ricky Ngok Shun Wong. (2007) Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chinese Medicine 2:1.
Crossref
Federica ChianaleSantina CutrupiElena RaineroGianluca Baldanzi, Paolo E. PorporatoSara TrainiNicoletta Filigheddu, Viola F. GnocchiMassimo M. SantoroOrnella Parolini, Wim J. van Blitterswijk, Fabiola SinigagliaAndrea Graziani. (2007) Diacylglycerol Kinase-α Mediates Hepatocyte Growth Factor-induced Epithelial Cell Scatter by Regulating Rac Activation and Membrane Ruffling. Molecular Biology of the Cell 18:12, pages 4859-4871.
Crossref
Adi D. Dubash, Krister Wennerberg, Rafael García-Mata, Marisa M. Menold, William T. Arthur & Keith Burridge. (2007) A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin. Journal of Cell Science 120:22, pages 3989-3998.
Crossref
Tiana A. Garrett, Jaap D. Van Buul & Keith Burridge. (2007) VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. Experimental Cell Research 313:15, pages 3285-3297.
Crossref
S L Miller, G Antico, P N Raghunath, J E Tomaszewski & C V Clevenger. (2007) Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells. Oncogene 26:32, pages 4668-4678.
Crossref
Lynda J. Peterson, Erika S. Wittchen, Pete Geisen, Keith Burridge & M. Elizabeth Hartnett. (2007) Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1. Experimental Eye Research 84:4, pages 737-744.
Crossref
Jin-Wen XuIkuo Morita, Katsumi IkedaTomohiro MikiYukio Yamori. (2007) C-Reactive Protein Suppresses Insulin Signaling in Endothelial Cells: Role of Spleen Tyrosine Kinase. Molecular Endocrinology 21:2, pages 564-573.
Crossref
Andrew C. PearceOwen J. T. MccartySimon D. J. CalaminusElena VigoritoMartin TurnerSteve P. Watson. (2007) Vav family proteins are required for optimal regulation of PLCγ2 by integrin αIIbβ3. Biochemical Journal 401:3, pages 753-761.
Crossref
Yan Liu, Minghua Zhu, Keigo Nishida, Toshio Hirano & Weiguo Zhang. (2007) An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response. Journal of Experimental Medicine 204:1, pages 93-103.
Crossref
Hiroaki Sakai, Yan Chen, Takashi Itokawa, Kuan-ping Yu, Mei-ling Zhu & Karl Insogna. (2006) Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts. Bone 39:6, pages 1290-1301.
Crossref
Martin R. Schiller. (2006) Coupling receptor tyrosine kinases to Rho GTPases—GEFs what's the link. Cellular Signalling 18:11, pages 1834-1843.
Crossref
Sarita K. Sastry, Zenon Rajfur, Betty P. Liu, Jean-Francois Cote, Michel L. Tremblay & Keith Burridge. (2006) PTP-PEST Couples Membrane Protrusion and Tail Retraction via VAV2 and p190RhoGAP. Journal of Biological Chemistry 281:17, pages 11627-11636.
Crossref
Michael L. Moeller, Yang Shi, Louis F. Reichardt & Iryna M. Ethell. (2006) EphB Receptors Regulate Dendritic Spine Morphogenesis through the Recruitment/Phosphorylation of Focal Adhesion Kinase and RhoA Activation. Journal of Biological Chemistry 281:3, pages 1587-1598.
Crossref
A.W. MacFarlaneIVIV & K. S. Campbell. 2006. Immunobiology of Natural Killer Cell Receptors. Immunobiology of Natural Killer Cell Receptors 23 57 .
Patrick Y.K. Yue, Daisy Y.L. Wong, W.Y. Ha, M.C. Fung, N.K. Mak, H.W. Yeung, H.W. Leung, Kelvin Chan, L. Liu, T.P.D. Fan & Ricky N.S. Wong. (2005) Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg1 in vivo and in vitro. Angiogenesis 8:3, pages 205-216.
Crossref
Sriparna Bagchi, Zhongji Liao, Fernando A. Gonzalez, Nataliya E. Chorna, Cheikh I. Seye, Gary A. Weisman & Laurie Erb. (2005) The P2Y2 Nucleotide Receptor Interacts with αv Integrins to Activate Go and Induce Cell Migration. Journal of Biological Chemistry 280:47, pages 39050-39057.
Crossref
Claire M. Wells, Parag J. Bhavsar, Iwan R. Evans, Elena Vigorito, Martin Turner, Victor Tybulewicz & Anne J. Ridley. (2005) Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Experimental Cell Research 310:2, pages 303-310.
Crossref
Elisabeth T. Barfod, Ann L. Moore, Richard F. Melnick & Steven D. Lidofsky. (2005) Src Regulates Distinct Pathways for Cell Volume Control through Vav andPhospholipaseCγ. Journal of Biological Chemistry 280:27, pages 25548-25557.
Crossref
Kazuhiro Aoki, Takeshi Nakamura, Keiko Fujikawa & Michiyuki Matsuda. (2005) Local Phosphatidylinositol 3,4,5-Trisphosphate Accumulation Recruits Vav2 and Vav3 to Activate Rac1/Cdc42 and Initiate Neurite Outgrowth in Nerve Growth Factor-stimulated PC12 Cells. Molecular Biology of the Cell 16:5, pages 2207-2217.
Crossref
Sommer L. MillerJamie E. DeMariaDavid O. FreierAngela M. Riegel & Charles V. Clevenger. (2005) Novel Association of Vav2 and Nek3 Modulates Signaling through the Human Prolactin Receptor. Molecular Endocrinology 19:4, pages 939-949.
Crossref
Christopher W. Cowan, Yu Raymond Shao, Mustafa Sahin, Steven M. Shamah, Michael Z. Lin, Paul L. Greer, Sizhen Gao, Eric C. Griffith, Joan S. Brugge & Michael E. Greenberg. (2005) Vav Family GEFs Link Activated Ephs to Endocytosis and Axon Guidance. Neuron 46:2, pages 205-217.
Crossref
M. Leabu, S. Uniyal, J. Xie, Y.Q. Xu, C. Vladau, V.L. Morris & B.M.C. Chan. (2005) Integrin ?2?1 modulates EGF stimulation of Rho GTPase-dependent morphological changes in adherent human rhabdomyosarcoma RD cells. Journal of Cellular Physiology 202:3, pages 754-766.
Crossref
Georg Rosenberger, Andreas Gal & Kerstin Kutsche. (2005) αPIX Associates with Calpain 4, the Small Subunit of Calpain, and Has a Dual Role in Integrin-mediated Cell Spreading. Journal of Biological Chemistry 280:8, pages 6879-6889.
Crossref
Tomomi Kawakatsu, Hisakazu Ogita, Tatsuro Fukuhara, Taihei Fukuyama, Yukiko Minami, Kazuya Shimizu & Yoshimi Takai. (2005) Vav2 as a Rac-GDP/GTP Exchange Factor Responsible for the Nectin-induced, c-Src- and Cdc42-mediated Activation of Rac. Journal of Biological Chemistry 280:6, pages 4940-4947.
Crossref
Ed Manser. 2005. RHO Family GTPases. RHO Family GTPases 1 18 .
Todd R. Palmby, Karon Abe, Antoine E. Karnoub & Channing J. Der. (2004) Vav Transformation Requires Activation of Multiple GTPases and Regulation of Gene Expression. Molecular Cancer Research 2:12, pages 702-711.
Crossref
Norbert Chauvet, Alain Privat & Monica Prieto. (2004) Differential expression of p120 catenin in glial cells of the adult rat brain. The Journal of Comparative Neurology 479:1, pages 15-29.
Crossref
William T. Arthur, Lawrence A. Quilliam & Jonathan A. Cooper. (2004) Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. Journal of Cell Biology 167:1, pages 111-122.
Crossref
Shougang Zhuang, Yujing Dang & Rick G. Schnellmann. (2004) Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration. American Journal of Physiology-Renal Physiology 287:3, pages F365-F372.
Crossref
Cheikh I. Seye, Ningpu Yu, Fernando A. González, Laurie Erb & Gary A. Weisman. (2004) The P2Y2 Nucleotide Receptor Mediates Vascular Cell Adhesion Molecule-1 Expression through Interaction with VEGF Receptor-2 (KDR/Flk-1). Journal of Biological Chemistry 279:34, pages 35679-35686.
Crossref
Shawn M. Ellerbroek, Krister Wennerberg, William T. Arthur, Jill M. Dunty, Dan R. Bowman, Kris A. DeMali, Channing Der & Keith Burridge. (2004) SGEF, a RhoG Guanine Nucleotide Exchange Factor that Stimulates Macropinocytosis. Molecular Biology of the Cell 15:7, pages 3309-3319.
Crossref
V.G Brunton, I.R.J MacPherson & M.C Frame. (2004) Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1692:2-3, pages 121-144.
Crossref
Patricia A. Solski, Rhonda S. Wilder, Kent L. Rossman, John Sondek, Adrienne D. Cox, Sharon L. Campbell & Channing J. Der. (2004) Requirement For C-terminal Sequences in Regulation of Ect2 Guanine Nucleotide Exchange Specificity and Transformation. Journal of Biological Chemistry 279:24, pages 25226-25233.
Crossref
Sandrine Etienne-Manneville. (2004) Cdc42 - the centre of polarity. Journal of Cell Science 117:8, pages 1291-1300.
Crossref
Lisa A. Fortier, Molly M. Deak, Stacy A. Semevolos & Richard A. Cerione. (2004) Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes. Journal of Orthopaedic Research 22:2, pages 436-445.
Crossref
Myrto Raftopoulou & Alan Hall. (2004) Cell migration: Rho GTPases lead the way. Developmental Biology 265:1, pages 23-32.
Crossref
Idit Hornstein, Andres Alcover & Shulamit Katzav. (2004) Vav proteins, masters of the world of cytoskeleton organization. Cellular Signalling 16:1, pages 1-11.
Crossref
P. Hilpelä, M. K. Vartiainen & P. Lappalainen. 2004. Phosphoinositides in Subcellular Targeting and Enzyme Activation. Phosphoinositides in Subcellular Targeting and Enzyme Activation 117 163 .
Marco A. Salazar, Adam V. Kwiatkowski, Lorenzo Pellegrini, Gianluca Cestra, Margaret H. Butler, Kent L. Rossman, Daniel M. Serna, John Sondek, Frank B. Gertler & Pietro De Camilli. (2003) Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton. Journal of Biological Chemistry 278:49, pages 49031-49043.
Crossref
Shine Tu, Wen Jin Wu, Jiabin Wang & Richard A. Cerione. (2003) Epidermal Growth Factor-dependent Regulation of Cdc42 Is Mediated by the Src Tyrosine Kinase. Journal of Biological Chemistry 278:49, pages 49293-49300.
Crossref
Annie-Carole Tosello-Trampont, Kumiko Nakada-Tsukui & Kodi S. Ravichandran. (2003) Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling. Journal of Biological Chemistry 278:50, pages 49911-49919.
Crossref
Kris A DeMali, Krister Wennerberg & Keith Burridge. (2003) Integrin signaling to the actin cytoskeleton. Current Opinion in Cell Biology 15:5, pages 572-582.
Crossref
Nathaly Marcoux & Kristiina Vuori. (2003) EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2. Oncogene 22:38, pages 6100-6106.
Crossref
Joan-Marc Servitja, Maria Julia Marinissen, Akrit Sodhi, Xosé R. Bustelo & J.Silvio Gutkind. (2003) Rac1 Function Is Required for Src-induced Transformation. Journal of Biological Chemistry 278:36, pages 34339-34346.
Crossref
Shobha Gopalakrishnan, Mark A. Hallett, Simon J. Atkinson & James. A. Marrs. (2003) Differential regulation of junctional complex assembly in renal epithelial cell lines. American Journal of Physiology-Cell Physiology 285:1, pages C102-C111.
Crossref
Jeffrey Chou, Nancy A Burke, Akihiro Iwabu, Simon C Watkins & Alan Wells. (2003) Directional motility induced by epidermal growth factor requires Cdc42. Experimental Cell Research 287:1, pages 47-56.
Crossref
Louis A. Roberts, Honor Glenn, Chang S. Hahn & Bruce S. Jacobson. (2003) Cdc42 and RhoA are differentially regulated during arachidonate-mediated HeLa cell adhesion. Journal of Cellular Physiology 196:1, pages 196-205.
Crossref
Norbert Chauvet, Monica Prieto, Christine Fabre, Nicole K Noren & Alain Privat. (2003) Distribution of p120 catenin during rat brain development:. Molecular and Cellular Neuroscience 22:4, pages 467-486.
Crossref
Péter Tamás, Zita Solti, Petra Bauer, András Illés, Szabolcs Sipeki, András Bauer, Anna Faragó, Julian Downward & László Buday. (2003) Mechanism of Epidermal Growth Factor Regulation of Vav2, a Guanine Nucleotide Exchange Factor for Rac. Journal of Biological Chemistry 278:7, pages 5163-5171.
Crossref
Karen McGee, Per Holmfeldt & Maria Fällman. (2003) Microtubule-dependent regulation of Rho GTPases during internalisation of Yersinia pseudotuberculosis . FEBS Letters 533:1, pages 35-41.
Crossref
Kris A. DeMali, Christy A. Barlow & Keith Burridge. (2002) Recruitment of the Arp2/3 complex to vinculin. Journal of Cell Biology 159:5, pages 881-891.
Crossref
Krister Wennerberg, Shawn M. Ellerbroek, Rong-Yu Liu, Antoine E. Karnoub, Keith Burridge & Channing J. Der. (2002) RhoG Signals in Parallel with Rac1 and Cdc42. Journal of Biological Chemistry 277:49, pages 47810-47817.
Crossref
Sarita K. Sastry, Patrick D. Lyons, Michael D. Schaller & Keith Burridge. (2002) PTP-PEST controls motility through regulation of Rac1. Journal of Cell Science 115:22, pages 4305-4316.
Crossref
Huiyan Zeng, Dezheng Zhao & Debabrata Mukhopadhyay. (2002) KDR Stimulates Endothelial Cell Migration through Heterotrimeric G Protein Gq/11-mediated Activation of a Small GTPase RhoA. Journal of Biological Chemistry 277:48, pages 46791-46798.
Crossref
Todd R. Palmby, Karon Abe & Channing J. Der. (2002) Critical Role of the Pleckstrin Homology and Cysteine-rich Domains in Vav Signaling and Transforming Activity. Journal of Biological Chemistry 277:42, pages 39350-39359.
Crossref
R.J Tolwani, P.S Buckmaster, S Varma, J.M Cosgaya, Y Wu, C Suri & E.M Shooter. (2002) BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus. Neuroscience 114:3, pages 795-805.
Crossref
Anja Schmidt & Alan Hall. (2002) Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes & Development 16:13, pages 1587-1609.
Crossref
Martin Turner & Daniel D. Billadeau. (2002) VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nature Reviews Immunology 2:7, pages 476-486.
Crossref
Natacha Edme, Julian Downward, Jean-Paul Thiery & Brigitte Boyer. (2002) Ras induces NBT-II epithelial cell scattering through the coordinate activities of Rac and MAPK pathways. Journal of Cell Science 115:12, pages 2591-2601.
Crossref
Pallavi Sachdev, Liyu Zeng & L.H. Wang. (2002) Distinct Role of Phosphatidylinositol 3-Kinase and Rho Family GTPases in Vav3-induced Cell Transformation, Cell Motility, and Morphological Changes. Journal of Biological Chemistry 277:20, pages 17638-17648.
Crossref
Justin Sturge, Jocelyne Hamelin & Gareth E. Jones. (2002) N-WASP activation by a β1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator. Journal of Cell Science 115:4, pages 699-711.
Crossref
Qize Wei & Robert S. Adelstein. (2002) Pitx2a Expression Alters Actin-Myosin Cytoskeleton and Migration of HeLa Cells through Rho GTPase Signaling. Molecular Biology of the Cell 13:2, pages 683-697.
Crossref
Zheng Li, Carlos D. Aizenman & Hollis T. Cline. (2002) Regulation of Rho GTPases by Crosstalk and Neuronal Activity In Vivo. Neuron 33:5, pages 741-750.
Crossref
Rachel Bar-Shavit, Miriam Maoz, Yin Yongjun, Maya Groysman, Idit Dekel & Shulamit Katzav. (2002) Signalling pathways induced by protease-activated receptors and integrins in T cells. Immunology 105:1, pages 35-46.
Crossref
Lilly Y.W. Bourguignon, Hongbo Zhu, Bo Zhou, Falko Diedrich, Patrick A. Singleton & Mien-Chie Hung. (2001) Hyaluronan Promotes CD44v3-Vav2 Interaction with Grb2-p185HER2 and Induces Rac1 and Ras Signaling during Ovarian Tumor Cell Migration and Growth. Journal of Biological Chemistry 276:52, pages 48679-48692.
Crossref
Scott A Weed & J Thomas Parsons. (2001) Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene 20:44, pages 6418-6434.
Crossref
Erik H.J. Danen & Kenneth M. Yamada. (2001) Fibronectin, integrins, and growth control. Journal of Cellular Physiology 189:1, pages 1-13.
Crossref
Giorgio Scita, Pierluigi Tenca, Liliana B. Areces, Arianna Tocchetti, Emanuela Frittoli, Giuseppina Giardina, Isabella Ponzanelli, Patrizia Sini, Metello Innocenti & Pier Paolo Di Fiore. (2001) An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine. Journal of Cell Biology 154:5, pages 1031-1044.
Crossref
Paola A. Marignani & Christopher L. Carpenter. (2001) Vav2 is required for cell spreading. Journal of Cell Biology 154:1, pages 177-186.
Crossref
Gary W. Reuther, Que T. Lambert, Michelle A. Booden, Krister Wennerberg, Brian Becknell, Guido Marcucci, John Sondek, Michael A. Caligiuri & Channing J. Der. (2001) Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA. Journal of Biological Chemistry 276:29, pages 27145-27151.
Crossref
Péter Tamás, Zita Solti & László Buday. (2001) Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor. Cellular Signalling 13:7, pages 475-481.
Crossref
Sophie Tartare-Deckert, Marie-Noëlle Monthouel, Céline Charvet, Isabelle Foucault, Emmanuel Van Obberghen, Alain Bernard, Amnon Altman & Marcel Deckert. (2001) Vav2 Activates c-fos Serum Response Element and CD69 Expression but Negatively Regulates Nuclear Factor of Activated T Cells and Interleukin-2 Gene Activation in T Lymphocyte. Journal of Biological Chemistry 276:24, pages 20849-20857.
Crossref
Mario Chiariello, Maria Julia Marinissen & J. Silvio Gutkind. (2001) Regulation of c-myc expression by PDGF through Rho GTPases. Nature Cell Biology 3:6, pages 580-586.
Crossref
Ardem Patapoutian & Louis F Reichardt. (2001) Trk receptors: mediators of neurotrophin action. Current Opinion in Neurobiology 11:3, pages 272-280.
Crossref
Juran Kato-Stankiewicz, Shuji Ueda, Tohru Kataoka, Yoshito Kaziro & Takaya Satoh. (2001) Epidermal Growth Factor Stimulation of the ACK1/Dbl Pathway in a Cdc42 and Grb2-Dependent Manner. Biochemical and Biophysical Research Communications 284:2, pages 470-477.
Crossref
Eric J HuangLouis F Reichardt. (2001) Neurotrophins: Roles in Neuronal Development and Function. Annual Review of Neuroscience 24:1, pages 677-736.
Crossref
Sarita K. Sastry & Keith Burridge. (2000) Focal Adhesions: A Nexus for Intracellular Signaling and Cytoskeletal Dynamics. Experimental Cell Research 261:1, pages 25-36.
Crossref

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