Advanced search
Publication Cover
Molecular and Cellular Biology Volume 20, 2000 - Issue 22
Submit an article Journal homepage
38
Views
112
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Acetylation by PCAF Enhances CIITA Nuclear Accumulation and Transactivation of Major Histocompatibility Complex Class II Genes

Charalambos Spilianakis1 Foundation for Research and Technology, Institute of Molecular Biology and Biotechnology;2 Department of Biology, University of Crete, Heraklion, Crete, Greece
,
Joseph Papamatheakis1 Foundation for Research and Technology, Institute of Molecular Biology and Biotechnology;2 Department of Biology, University of Crete, Heraklion, Crete, GreeceCorrespondence[email protected]
&
Androniki Kretsovali1 Foundation for Research and Technology, Institute of Molecular Biology and Biotechnology
Pages 8489-8498 | Received 15 May 2000, Accepted 21 Aug 2000, Published online: 28 Mar 2023

Citations (112)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (10)

Priya Londhe & Judith K. Davie. (2011) Gamma Interferon Modulates Myogenesis through the Major Histocompatibility Complex Class II Transactivator, CIITA. Molecular and Cellular Biology 31:14, pages 2854-2866.
Read now
Manolis Gialitakis, Panagiota Arampatzi, Takis Makatounakis & Joseph Papamatheakis. (2010) Gamma Interferon-Dependent Transcriptional Memory via Relocalization of a Gene Locus to PML Nuclear Bodies. Molecular and Cellular Biology 30:8, pages 2046-2056.
Read now
Xiaoyan Wu, Xiaocen Kong, Larry Luchsinger, Barbara D. Smith & Yong Xu. (2009) Regulating the Activity of Class II Transactivator by Posttranslational Modifications: Exploring the Possibilities. Molecular and Cellular Biology 29:21, pages 5639-5644.
Read now
Eun Joo Chung, Min-Jung Lee, Sunmin Lee & Jane B Trepel. (2006) Assays for pharmacodynamic analysis of histone deacetylase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 2:2, pages 213-230.
Read now
Eleni Zika, Susanna F. Greer, Xin-Sheng Zhu & Jenny P.-Y. Ting. (2003) Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation. Molecular and Cellular Biology 23:9, pages 3091-3102.
Read now
Rajini Mudhasani & Joseph D. Fontes. (2002) The Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes. Molecular and Cellular Biology 22:14, pages 5019-5026.
Read now
Ann C. Morris, Guy W. Beresford, Myesha R. Mooney & Jeremy M. Boss. (2002) Kinetics of a Gamma Interferon Response: Expression and Assembly of CIITA Promoter IV and Inhibition by Methylation. Molecular and Cellular Biology 22:13, pages 4781-4791.
Read now
Ya-Li Yao, Wen-Ming Yang & Edward Seto. (2001) Regulation of Transcription Factor YY1 by Acetylation and Deacetylation. Molecular and Cellular Biology 21:17, pages 5979-5991.
Read now
Tyler J. Sisk, Stacey Roys & Cheong-Hee Chang. (2001) Self-Association of CIITA and Its Transactivation Potential. Molecular and Cellular Biology 21:15, pages 4919-4928.
Read now
Michael W. Linhoff, Jonathan A. Harton, Drew E. Cressman, Brian K. Martin & Jenny Pan-Yun Ting. (2001) Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains. Molecular and Cellular Biology 21:9, pages 3001-3011.
Read now

Articles from other publishers (102)

Ayano Inoue, Masashi Watanabe, Takeshi Kondo, Satoshi Hirano & Shigetsugu Hatakeyama. (2022) TRIM22 negatively regulates MHC-II expression. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1869:10, pages 119318.
Crossref
Grady Nash, Bhaskar Paidimuddala & Liman Zhang. (2022) Structural aspects of the MHC expression control system. Biophysical Chemistry 284, pages 106781.
Crossref
Michael Downey. (2021) Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:2, pages 194608.
Crossref
Jorge Alfonso León Machado & Viktor Steimle. (2021) The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins. International Journal of Molecular Sciences 22:3, pages 1074.
Crossref
Titin Andri Wihastuti, Wiwit Nurwidyaningtyas, Fibe Yulinda Cesa & Cholid Tri Tjahjono. (2020) Cytoplasm and nuclear crude protein proportion observed in pheripheral blood mono nuclear cells under senescence inducing stress exposure. Journal of Physics: Conference Series 1665, pages 012034.
Crossref
Cyril S. Anyetei-Anum, Rochelle M. Evans, Amanda M. Back, Vincent R. Roggero & Lizabeth A. Allison. (2019) Acetylation modulates thyroid hormone receptor intracellular localization and intranuclear mobility. Molecular and Cellular Endocrinology 495, pages 110509.
Crossref
Nur P. Damayanti, Kevin Buno, Sherry L. Voytik Harbin & Joseph M. K. Irudayaraj. (2019) Epigenetic Process Monitoring in Live Cultures with Peptide Biosensors. ACS Sensors 4:3, pages 562-565.
Crossref
Saptha Vijayan, Tabasum Sidiq, Suhail Yousuf, Peter J. van den Elsen & Koichi S. Kobayashi. (2019) Class I transactivator, NLRC5: a central player in the MHC class I pathway and cancer immune surveillance. Immunogenetics 71:3, pages 273-282.
Crossref
Emma Bondy-ChorneyAlix DenoncourtYuka SaiMichael Downey. (2019) Nonhistone targets of KAT2A and KAT2B implicated in cancer biology. Biochemistry and Cell Biology 97:1, pages 30-45.
Crossref
David Briere, Niranjan Sudhakar, David M. Woods, Jill Hallin, Lars D. Engstrom, Ruth Aranda, Harrah Chiang, Andressa L. Sodré, Peter Olson, Jeffrey S. Weber & James G. Christensen. (2017) The class I/IV HDAC inhibitor mocetinostat increases tumor antigen presentation, decreases immune suppressive cell types and augments checkpoint inhibitor therapy. Cancer Immunology, Immunotherapy 67:3, pages 381-392.
Crossref
Liming Yu, Zilong Li, Mingming Fang & Yong Xu. (2017) Acetylation of MKL1 by PCAF regulates pro-inflammatory transcription. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:8, pages 839-847.
Crossref
M L Palma, P Duangkhae, B Douradinha, I F T Viana, P O Rigato, R Dhalia, R B Mailliard, S M Barratt-Boyes, E J M Nascimento, T M Oshiro, A J da Silva Duarte & E T A Marques. (2017) Development of potent class II transactivator gene delivery systems capable of inducing de novo MHC II expression in human cells, in vitro and ex vivo. Gene Therapy 24:6, pages 342-352.
Crossref
Nikoleta Sachini & Joseph Papamatheakis. (2017) NF-Y and the immune response: Dissecting the complex regulation of MHC genes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:5, pages 537-542.
Crossref
Zhiwen Fan, Jianfei Li, Ping Li, Qing Ye, Huihui Xu, Xiaoyan Wu & Yong Xu. (2017) Protein arginine methyltransferase 1 (PRMT1) represses MHC II transcription in macrophages by methylating CIITA. Scientific Reports 7:1.
Crossref
Julie E. Morgan & Susanna F. Greer. (2017) Pulling a Ligase out of a “HAT”: pCAF Mediates Ubiquitination of the Class II Transactivator. International Journal of Cell Biology 2017, pages 1-11.
Crossref
K. Suzuki & Y. Luo. 2017. Chromatin Remodelling and Immunity. Chromatin Remodelling and Immunity 71 111 .
S.T. Chelbi, A.T. Dang & G. Guarda. 2017. 89 119 .
Julie E. MorganRonald L. ShandersonNathaniel H. BoydErcan CacanSusanna F. Greer. (2015) The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys63 ubiquitination. Bioscience Reports 35:4.
Crossref
Emily Chiu, Theresa Gold, Veronica Fettig, Michael T. LeVasseur & Drew E. Cressman. (2015) Identification of a Nuclear Export Sequence in the MHC CIITA. The Journal of Immunology 194:12, pages 6102-6111.
Crossref
Christopher D. Scharer, Nancy M. Choi, Benjamin G. Barwick, Parimal Majumder, Sarah Lohsen & Jeremy M. Boss. (2015) Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment. Nucleic Acids Research 43:6, pages 3128-3142.
Crossref
François Barbé, Todd Douglas & Maya Saleh. (2014) Advances in Nod-like receptors (NLR) biology. Cytokine & Growth Factor Reviews 25:6, pages 681-697.
Crossref
Jhih-Rong Lin, Zhonghao Liu & Jianjun Hu. (2014) Computational identification of post-translational modification-based nuclear import regulations by characterizing nuclear localization signal-import receptor interaction. Proteins: Structure, Function, and Bioinformatics 82:10, pages 2783-2796.
Crossref
Manila HadaRoland P.S. Kwok. (2014) Regulation of Ku70-Bax Complex in Cells. Journal of Cell Death 7, pages JCD.S13695.
Crossref
Panagiota Arampatzi, Manolis Gialitakis, Takis Makatounakis & Joseph Papamatheakis. (2013) Gene-specific factors determine mitotic expression and bookmarking via alternate regulatory elements. Nucleic Acids Research 41:4, pages 2202-2215.
Crossref
Koichi S. Kobayashi & Peter J. van den Elsen. (2012) NLRC5: a key regulator of MHC class I-dependent immune responses. Nature Reviews Immunology 12:12, pages 813-820.
Crossref
Tobias Ulbricht, Mohammad Alzrigat, Almut Horch, Nina Reuter, Anna von Mikecz, Viktor Steimle, Eberhard Schmitt, Oliver H. Krämer, Thomas Stamminger & Peter Hemmerich. (2012) PML promotes MHC class II gene expression by stabilizing the class II transactivator. Journal of Cell Biology 199:1, pages 49-63.
Crossref
Tuo Li, Benjamin A. Diner, Jin Chen & Ileana M. Cristea. (2012) Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16. Proceedings of the National Academy of Sciences 109:26, pages 10558-10563.
Crossref
Torsten B. Meissner, Amy Li & Koichi S. Kobayashi. (2012) NLRC5: a newly discovered MHC class I transactivator (CITA). Microbes and Infection 14:6, pages 477-484.
Crossref
Nancy M. Choi & Jeremy M. Boss. (2012) Multiple Histone Methyl and Acetyltransferase Complex Components Bind the HLA-DRA Gene. PLoS ONE 7:5, pages e37554.
Crossref
Torsten B. Meissner, Amy Li, Yuen-Joyce Liu, Etienne Gagnon & Koichi S. Kobayashi. (2012) The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity. Biochemical and Biophysical Research Communications 418:4, pages 786-791.
Crossref
Pablo Minguez, Luca Parca, Francesca Diella, Daniel R Mende, Runjun Kumar, Manuela Helmer‐Citterich, Anne‐Claude Gavin, Vera van Noort & Peer Bork. (2012) Deciphering a global network of functionally associated post‐translational modifications. Molecular Systems Biology 8:1.
Crossref
Rami Doueiri & Patrick L. Green. 2012. Cancer Associated Viruses. Cancer Associated Viruses 647 675 .
Chiara Orlandi, Greta Forlani, Giovanna Tosi & Roberto S Accolla. (2011) Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication. Journal of Translational Medicine 9:1.
Crossref
Xiaoyan Wu, Xiaocen Kong, Dewei Chen, He Li, Yuhao Zhao, Minjie Xia, Mingming Fang, Ping Li, Fei Fang, Lina Sun, Wenfang Tian, Huihui Xu, Yuyu Yang, Xiaohong Qi, Yuqi Gao, Jiahao Sha, Qi Chen & Yong Xu. (2011) SIRT1 links CIITA deacetylation to MHC II activation. Nucleic Acids Research 39:22, pages 9549-9558.
Crossref
Giovanna Tosi, Greta Forlani, Vibeke Andresen, Marco Turci, Umberto Bertazzoni, Genoveffa Franchini, Guido Poli & Roberto S. Accolla. (2011) Major Histocompatibility Complex Class II Transactivator CIITA Is a Viral Restriction Factor That Targets Human T-Cell Lymphotropic Virus Type 1 Tax-1 Function and Inhibits Viral Replication. Journal of Virology 85:20, pages 10719-10729.
Crossref
Nancy M Choi, Parimal Majumder & Jeremy M Boss. (2011) Regulation of major histocompatibility complex class II genes. Current Opinion in Immunology 23:1, pages 81-87.
Crossref
Karin Sadoul, Jin Wang, Boubou Diagouraga & Saadi Khochbin. (2011) The Tale of Protein Lysine Acetylation in the Cytoplasm. Journal of Biomedicine and Biotechnology 2011, pages 1-15.
Crossref
Peter J. van den Elsen, Marja C. J. A. van Eggermond & Rutger J. Wierda. 2011. Epigenetic Contributions in Autoimmune Disease. Epigenetic Contributions in Autoimmune Disease 36 49 .
Torsten B. MeissnerAmy LiAmlan BiswasKyoung-Hee LeeYuen-Joyce LiuErkan BayirDimitrios IliopoulosPeter J. van den Elsen & Koichi S. Kobayashi. (2010) NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. Proceedings of the National Academy of Sciences 107:31, pages 13794-13799.
Crossref
Kavita Purnanda Bhat, Agnieszka Dorota Truax & Susanna Fletcher Greer. (2010) Phosphorylation and Ubiquitination of Degron Proximal Residues Are Essential for Class II Transactivator (CIITA) Transactivation and Major Histocompatibility Class II Expression. Journal of Biological Chemistry 285:34, pages 25893-25903.
Crossref
Annie Rodolosse, Maria-Luisa Campos, Ilse Rooman, Mathieu Lichtenstein & Francisco X. Real. (2009) p/CAF modulates the activity of the transcription factor p48/Ptf1a involved in pancreatic acinar differentiation. Biochemical Journal 418:2, pages 463-473.
Crossref
Nicholas E.S. Sibinga. (2009) Stable protein, unstable plaque?. Journal of Molecular and Cellular Cardiology 46:3, pages 289-291.
Crossref
Xiaocen Kong, Mingming Fang, Ping Li, Fei Fang & Yong Xu. (2009) HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. Journal of Molecular and Cellular Cardiology 46:3, pages 292-299.
Crossref
Xinjian Ge, Qihuang Jin, Fang Zhang, Tingting Yan & Qiwei Zhai. (2009) PCAF Acetylates β-Catenin and Improves Its Stability. Molecular Biology of the Cell 20:1, pages 419-427.
Crossref
Noemí Blanco-García, Elena Asensio-Juan, Xavier de la Cruz & Marian A. Martínez-Balbás. (2009) Autoacetylation Regulates P/CAF Nuclear Localization. Journal of Biological Chemistry 284:3, pages 1343-1352.
Crossref
Sandra S Haenni, Matthias Altmeyer, Paul O Hassa, Taras Valovka, Monika Fey & Michael O Hottiger. (2008) Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS. BMC Cell Biology 9:1.
Crossref
Colin W. Garvie & Jeremy M. Boss. (2008) Assembly of the RFX complex on the MHCII promoter: Role of RFXAP and RFXB in relieving autoinhibition of RFX5. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1779:12, pages 797-804.
Crossref
Lilien N. Voong, Allison R. Slater, Sebila Kratovac & Drew E. Cressman. (2008) Mitogen-activated Protein Kinase ERK1/2 Regulates the Class II Transactivator. Journal of Biological Chemistry 283:14, pages 9031-9039.
Crossref
Yong Xu, Jonathan A. Harton & Barbara D. Smith. (2008) CIITA Mediates Interferon-γ Repression of Collagen Transcription through Phosphorylation-dependent Interactions with Co-repressor Molecules. Journal of Biological Chemistry 283:3, pages 1243-1256.
Crossref
Nadine N. Bewry, Sophia C.E. Bolick, Kenneth L. Wright & Jonathan A. Harton. (2007) GTP-dependent Recruitment of CIITA to the Class II Major Histocompatibility Complex Promoter. Journal of Biological Chemistry 282:36, pages 26178-26184.
Crossref
Natalia Rybtsova, Elisa Leimgruber, Queralt Seguin-Estévez, Isabelle Dunand-Sauthier, Michal Krawczyk & Walter Reith. (2007) Transcription-coupled deposition of histone modifications during MHC class II gene activation. Nucleic Acids Research 35:10, pages 3431-3441.
Crossref
Wafa Al-Kandari, Srikarthika Jambunathan, Vandana Navalgund, Rupa Koneni, Margot Freer, Neeta Parimi, Rajini Mudhasani & Joseph D. Fontes. (2007) ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription. Molecular Immunology 44:4, pages 311-321.
Crossref
Gorazd Drozina, Jiri Kohoutek, Tadashi Nishiya & B. Matija Peterlin. (2006) Sequential Modifications in Class II Transactivator Isoform 1 Induced by Lipopolysaccharide Stimulate Major Histocompatibility Complex Class II Transcription in Macrophages. Journal of Biological Chemistry 281:52, pages 39963-39970.
Crossref
A Masumi, H Fukazawa, T Shimazu, M Yoshida, K Ozato, K Komuro & K Yamaguchi. (2006) Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation. Oncogene 25:37, pages 5113-5124.
Crossref
Giovanna Tosi, Elisabetta Pilotti, Lorenzo Mortara, Andrea De Lerma Barbaro, Claudio Casoli & Roberto S. Accolla. (2006) Inhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y. Proceedings of the National Academy of Sciences 103:34, pages 12861-12866.
Crossref
Maria Giovanna di Bari, Laura Ciuffini, Michele Mingardi, Roberto Testi, Silvia Soddu & Daniela Barilà. (2006) c‐Abl acetylation by histone acetyltransferases regulates its nuclear–cytoplasmic localization. EMBO reports 7:7, pages 727-733.
Crossref
M. Krawczyk & W. Reith. (2006) Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease. Tissue Antigens 67:3, pages 183-197.
Crossref
W. -H. Huang, C. -W. Chen, H. -L. Wu & P. -J. Chen. 2006. Hepatitis Delta Virus. Hepatitis Delta Virus 91 112 .
Eleni Zika, Lucas Fauquier, Laurence Vandel & Jenny P.-Y. Ting. (2005) Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-γ-inducible MHC-II gene expression. Proceedings of the National Academy of Sciences 102:45, pages 16321-16326.
Crossref
Joanne Cleary, Kajal V. Sitwala, Michael S. Khodadoust, Roland P.S. Kwok, Nirit Mor-Vaknin, Marek Cebrat, Philip A. Cole & David M. Markovitz. (2005) p300/CBP-associated Factor Drives DEK into Interchromatin Granule Clusters. Journal of Biological Chemistry 280:36, pages 31760-31767.
Crossref
Audrey H. Wang, Serge Grégoire, Eleni Zika, Lin Xiao, Cathy S. Li, Hongwei Li, Kenneth L. Wright, Jenny P. Ting & Xiang-Jiao Yang. (2005) Identification of the Ankyrin Repeat Proteins ANKRA and RFXANK as Novel Partners of Class IIa Histone Deacetylases. Journal of Biological Chemistry 280:32, pages 29117-29127.
Crossref
Eleni Zika & Jenny P-Y Ting. (2005) Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Current Opinion in Immunology 17:1, pages 58-64.
Crossref
Andrea De Lerma Barbaro, Francesco?A. Procopio, Lorenzo Mortara, Giovanna Tosi & Roberto?S. Accolla. (2005) The MHC class?II transactivator (CIITA) mRNA stability is critical for the HLA class?II gene expression in myelomonocytic cells. European Journal of Immunology 35:2, pages 603-611.
Crossref
Dipak R. Patel, Wei Li, Jae-Seung Park, M. Hanief Sofi, Tania S. Gourley, Gaio Hangoc, Mark H. Kaplan & Cheong-Hee Chang. (2005) Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus. Cellular Immunology 233:1, pages 30-40.
Crossref
G. Drozina, J. Kohoutek, N. Jabrane-Ferrat & B. M. Peterlin. 2005. Molecular Analysis of B Lymphocyte Development and Activation. Molecular Analysis of B Lymphocyte Development and Activation 147 170 .
Yong Xu, Lin Wang, Giovanna Butticè, Pritam K. Sengupta & Barbara D. Smith. (2004) Major Histocompatibility Class II Transactivator (CIITA) Mediates Repression of Collagen (COL1A2) Transcription by Interferon γ (IFN-γ). Journal of Biological Chemistry 279:40, pages 41319-41332.
Crossref
Xiang-Jiao Yang. (2004) Lysine acetylation and the bromodomain: a new partnership for signaling. BioEssays 26:10, pages 1076-1087.
Crossref
Tjadine M Holling, Nienke Van der Stoep & Peter J Van den Elsen. (2004) Epigenetic control of CIITA expression in leukemic T cells. Biochemical Pharmacology 68:6, pages 1209-1213.
Crossref
Jill Adamski, Zhendong Ma, Susan Nozell & Etty N. Benveniste. (2004) 17β-Estradiol Inhibits Class II Major Histocompatibility Complex (MHC) Expression: Influence on Histone Modifications and CBP Recruitment to the Class II MHC Promoter. Molecular Endocrinology 18:8, pages 1963-1974.
Crossref
Susanna F. Greer, Jonathan A. Harton, Michael W. Linhoff, Christin A. Janczak, Jenny P.-Y. Ting & Drew E. Cressman. (2004) Serine Residues 286, 288, and 293 within the CIITA: A Mechanism for Down-Regulating CIITA Activity through Phosphorylation. The Journal of Immunology 173:1, pages 376-383.
Crossref
T Prod'homme, B Drénou, C De Ruyffelaere, G Barbieri, W Wiszniewski, C Bastard, D Charron & C Alcaide-Loridan. (2004) Defective class II transactivator expression in a B lymphoma cell line. Leukemia 18:4, pages 832-840.
Crossref
Claudio CasoliAndrea De Lerma BarbaroElisabetta PilottiUmberto BertazzoniGiovanna TosiRoberto S. Accolla. (2004) The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2. Blood 103:3, pages 995-1001.
Crossref
Jung-Jung Mu, Yeou-Guang Tsay, Li-Jung Juan, Tsai-Feng Fu, Wen-Hung Huang, Ding-Shinn Chen & Pei-Jer Chen. (2004) The small delta antigen of hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular localization and viral RNA synthesis. Virology 319:1, pages 60-70.
Crossref
Peter J van den Elsen, Tjadine M Holling, Hedwich F Kuipers & Nienke van der Stoep. (2004) Transcriptional regulation of antigen presentation. Current Opinion in Immunology 16:1, pages 67-75.
Crossref
Ho Jung Oh, Eun Joo Chung, Sunmin Lee, Andrea Loaiza-Perez, Edward A. Sausville & Jane B. Trepel. 2004. Cancer Chemoprevention. Cancer Chemoprevention 659 678 .
Eleni Tzortzakaki, Charalambos Spilianakis, Eleni Zika, Androniki Kretsovali & Joseph Papamatheakis. (2003) Steroid Receptor Coactivator 1 Links the Steroid and Interferon γ Response Pathways. Molecular Endocrinology 17:12, pages 2509-2518.
Crossref
Yong Xu, Lin Wang, Giovanna Butticè, Pritam K. Sengupta & Barbara D. Smith. (2003) Interferon γ Repression of Collagen (COL1A2) Transcription Is Mediated by the RFX5 Complex. Journal of Biological Chemistry 278:49, pages 49134-49144.
Crossref
Lisa Y Zhao, Yue Liu, Nicholas R Bertos, Xiang-Jiao Yang & Daiqing Liao. (2003) PCAF is a coactivator for p73-mediated transactivation. Oncogene 22:51, pages 8316-8329.
Crossref
Susanna F Greer, Eleni Zika, Brian Conti, Xin-Sheng Zhu & Jenny P-Y Ting. (2003) Enhancement of CIITA transcriptional function by ubiquitin. Nature Immunology 4:11, pages 1074-1082.
Crossref
Michela Croce, Alessandro De Ambrosis, Maria V Corrias, Vito Pistoia, Marzia Occhino, Raffaella Meazza, Julien Giron-Michel, Bruno Azzarone, Roberto S Accolla & Silvano Ferrini. (2003) Different levels of control prevent interferon-γ-inducible HLA-class II expression in human neuroblastoma cells. Oncogene 22:49, pages 7848-7857.
Crossref
Renae Holtz, Jason C. Choi, Margaret G. Petroff, Janet F. Piskurich & Shawn P. Murphy. (2003) Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts1. Biology of Reproduction 69:3, pages 915-924.
Crossref
Vitalyi Senyuk, Kislay Kumar Sinha, Soumen Chakraborty, Silvia Buonamici & Giuseppina Nucifora. (2003) P/CAF and GCN5 acetylate the AML1/MDS1/EVI1 fusion oncoprotein. Biochemical and Biophysical Research Communications 307:4, pages 980-986.
Crossref
Nikita Avvakumov, Joe Torchia & Joe S Mymryk. (2003) Interaction of the HPV E7 proteins with the pCAF acetyltransferase. Oncogene 22:25, pages 3833-3841.
Crossref
Jeremy M Boss & Peter E Jensen. (2003) Transcriptional regulation of the MHC class II antigen presentation pathway. Current Opinion in Immunology 15:1, pages 105-111.
Crossref
Aparna Raval, Jocelyn D. Weissman, T. Kevin Howcroft & Dinah S. Singer. (2003) The GTP-Binding Domain of Class II Transactivator Regulates Its Nuclear Export. The Journal of Immunology 170:2, pages 922-930.
Crossref
Masahiko Okada & Kuan-Teh Jeang. (2002) Differential Requirements for Activation of Integrated and Transiently Transfected Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat. Journal of Virology 76:24, pages 12564-12573.
Crossref
Gil Blander, Noa Zalle, Yaron Daniely, Jan Taplick, Matthew D. Gray & Moshe Oren. (2002) DNA Damage-induced Translocation of the Werner Helicase Is Regulated by Acetylation. Journal of Biological Chemistry 277:52, pages 50934-50940.
Crossref
Santasabuj Das, Jun-Hsiang Lin, Joseph Papamatheakis, Yuri Sykulev & Philip N. Tsichlis. (2002) Differential Splicing Generates Tvl-1/RFXANK Isoforms with Different Functions. Journal of Biological Chemistry 277:47, pages 45172-45180.
Crossref
Nada Nekrep, Nabila Jabrane-Ferrat, Hermann M. Wolf, Martha M. Eibl, Matthias Geyer & B. Matija Peterlin. (2002) Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome. Nature Immunology 3:11, pages 1075-1081.
Crossref
Shih-Min Huang & D. J. McCance. (2002) Down Regulation of the Interleukin-8 Promoter by Human Papillomavirus Type 16 E6 and E7 through Effects on CREB Binding Protein/p300 and P/CAF. Journal of Virology 76:17, pages 8710-8721.
Crossref
Jonathan A Harton, William O’ConnorJr.Jr., Brian J Conti, Michael W Linhoff & Jenny P.-Y Ting. (2002) Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Human Immunology 63:7, pages 588-601.
Crossref
Jenny Pan-Yun Ting & John Trowsdale. (2002) Genetic Control of MHC Class II Expression. Cell 109:2, pages S21-S33.
Crossref
Michael Towey & Adrian P. Kelly. (2002) Nuclear localisation of CIITA is controlled by a carboxy terminal leucine-rich repeat region. Molecular Immunology 38:8, pages 627-634.
Crossref
Rajini Mudhasani & Joseph D Fontes. (2002) Inhibition of class II trans-activator function by HIV-1 tat in mouse cells is independent of competition for binding to cyclin T1. Molecular Immunology 38:7, pages 539-546.
Crossref
Sam J. P. Gobin, Marlijn van Zutphen, Sandy D. Westerheide, Jeremy M. Boss & Peter J. van den Elsen. (2001) The MHC-Specific Enhanceosome and Its Role in MHC Class I and β2-Microglobulin Gene Transactivation. The Journal of Immunology 167:9, pages 5175-5184.
Crossref
Drew E. Cressman, William J. O’Connor, Susanna F. Greer, Xin-Sheng Zhu & Jenny P.-Y. Ting. (2001) Mechanisms of Nuclear Import and Export That Control the Subcellular Localization of Class II Transactivator. The Journal of Immunology 167:7, pages 3626-3634.
Crossref
Jonathan A. Harton, Eleni Zika & Jenny P.-Y. Ting. (2001) The Histone Acetyltransferase Domains of CREB-binding Protein (CBP) and p300/CBP-associated Factor Are Not Necessary for Cooperativity with the Class II Transactivator. Journal of Biological Chemistry 276:42, pages 38715-38720.
Crossref
Naohiro Inohara & Gabriel Nuñez. (2001) The NOD: a signaling module that regulates apoptosis and host defense against pathogens. Oncogene 20:44, pages 6473-6481.
Crossref
Lin-feng ChenWolfgang FischleEric VerdinWarner C. Greene. (2001) Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation. Science 293:5535, pages 1653-1657.
Crossref
Androniki Kretsovali, Charalambos Spilianakis, Andreas Dimakopoulos, Takis Makatounakis & Joseph Papamatheakis. (2001) Self-association of Class II Transactivator Correlates with Its Intracellular Localization and Transactivation. Journal of Biological Chemistry 276:34, pages 32191-32197.
Crossref
Guy W. Beresford & Jeremy M. Boss. (2001) CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter. Nature Immunology 2:7, pages 652-657.
Crossref
Hongwu Chen, Marc Tini & Ronald M Evans. (2001) HATs on and beyond chromatin. Current Opinion in Cell Biology 13:2, pages 218-224.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.