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Molecular and Cellular Biology Volume 20, 2000 - Issue 24
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Transcriptional Regulation

Retinoblastoma Protein Disrupts Interactions Required for RNA Polymerase III Transcription

Josephine E. SutcliffeInstitute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, University of Glasgow, GlasgowG12 8QQ, United Kingdom
,
Timothy R. P. BrownInstitute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, University of Glasgow, GlasgowG12 8QQ, United Kingdom
,
Simon J. AllisonInstitute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, University of Glasgow, GlasgowG12 8QQ, United Kingdom
,
Pamela H. ScottInstitute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, University of Glasgow, GlasgowG12 8QQ, United Kingdom
&
Robert J. WhiteInstitute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, University of Glasgow, GlasgowG12 8QQ, United KingdomCorrespondence[email protected]
Pages 9192-9202 | Received 12 May 2000, Accepted 07 Sep 2000, Published online: 28 Mar 2023

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Dhaval Varshney, Jana Vavrova-Anderson, Andrew J Oler, Bradley R Cairns & Robert J White. (2015) Selective repression of SINE transcription by RNA polymerase III. Mobile Genetic Elements 5:6, pages 86-91.
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Adelene Y. Tan & James L. Manley. (2010) TLS Inhibits RNA Polymerase III Transcription. Molecular and Cellular Biology 30:1, pages 186-196.
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Annette Woiwode, Sandra A. S. Johnson, Shuping Zhong, Cheng Zhang, Robert G. Roeder, Martin Teichmann & Deborah L. Johnson. (2008) PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex. Molecular and Cellular Biology 28:12, pages 4204-4214.
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Heather A. Hirsch, Gauri W. Jawdekar, Kang-Ae Lee, Liping Gu & R. William Henry. (2004) Distinct Mechanisms for Repression of RNA Polymerase III Transcription by the Retinoblastoma Tumor Suppressor Protein. Molecular and Cellular Biology 24:13, pages 5989-5999.
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Imogen M. Johnston, Simon J. Allison, Jennifer P. Morton, Laura Schramm, Pamela H. Scott & Robert J. White. (2002) CK2 Forms a Stable Complex with TFIIIB and Activates RNA Polymerase III Transcription in Human Cells. Molecular and Cellular Biology 22:11, pages 3757-3768.
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Sonia Ciarmatori, Pamela H. Scott, Josephine E. Sutcliffe, Angela McLees, Hadi M. Alzuherri, Jan-Hermen Dannenberg, Hein te Riele, Ingrid Grummt, Renate Voit & Robert J. White. (2001) Overlapping Functions of the pRb Family in the Regulation of rRNA Synthesis. Molecular and Cellular Biology 21:17, pages 5806-5814.
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Juan Wang, Qiyue Chen, Xin Wang, Shasha Zhao, Huan Deng, Baoqiang Guo, Cheng Zhang, Xiaoye Song, Wensheng Deng, Tongcun Zhang & Hongwei Ni. (2023) TFIIB-related factor 1 is a nucleolar protein that promotes RNA polymerase I-directed transcription and tumour cell growth. Human Molecular Genetics 32:1, pages 104-121.
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Esteban A. Orellana, Elisabeth Siegal & Richard I. Gregory. (2022) tRNA dysregulation and disease. Nature Reviews Genetics 23:11, pages 651-664.
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Rebecca E. Sizer, Nisreen Chahid, Sienna P. Butterfield, David Donze, Nia J. Bryant & Robert J. White. (2022) TFIIIC-based chromatin insulators through eukaryotic evolution. Gene 835, pages 146533.
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Ellen Phillips, Naseer Ahmad, Li Sun, James Iben, Christopher J Walkey, Aleksandra Rusin, Tony Yuen, Clifford J Rosen, Ian M Willis, Mone Zaidi & Deborah L Johnson. (2022) MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass. eLife 11.
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Richard J. Acton, Wei Yuan, Fei Gao, Yudong Xia, Emma Bourne, Eva Wozniak, Jordana Bell, Karen Lillycrop, Jun Wang, Elaine Dennison, Nicholas C. Harvey, Charles A. Mein, Tim D. Spector, Pirro G. Hysi, Cyrus Cooper & Christopher G. Bell. (2021) The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation. Nature Communications 12:1.
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Fang Wang, Kailiang Zhao, Sixiang Yu, An Xu, Wei Han & Yide Mei. (2019) RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III–dependent transcription. Journal of Biological Chemistry 294:1, pages 130-141.
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X Xie, P Guo, H Yu, Y Wang & G Chen. (2017) Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma. Oncogene 37:3, pages 277-285.
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Junxia Lei, Songlin Chen & Shuping Zhong. (2017) WITHDRAWN: Abnormal expression of TFIIIB subunits and RNA Pol III genes is associated with hepatocellular carcinoma. Liver Research.
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Junxia Lei, Songlin Chen & Shuping Zhong. (2017) Abnormal expression of TFIIIB subunits and RNA Pol III genes is associated with hepatocellular carcinoma. Liver Research 1:2, pages 112-120.
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Tomasz W. TurowskiDavid Tollervey. (2016) Transcription by RNA polymerase III: insights into mechanism and regulation. Biochemical Society Transactions 44:5, pages 1367-1375.
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Savraj S. Grewal. (2015) Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:7, pages 898-907.
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Xiang Zhou, Wen-Juan Liao, Jun-Ming Liao, Peng Liao & Hua Lu. (2015) Ribosomal proteins: functions beyond the ribosome. Journal of Molecular Cell Biology 7:2, pages 92-104.
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Dhaval Varshney, Jana Vavrova-Anderson, Andrew J. Oler, Victoria H. Cowling, Bradley R. Cairns & Robert J. White. (2015) SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation. Nature Communications 6:1.
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Karen E. Sheppard & Grant A. McArthur. (2013) The Cell-Cycle Regulator CDK4: An Emerging Therapeutic Target in Melanoma. Clinical Cancer Research 19:19, pages 5320-5328.
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M-C Yen, T-Y Weng, Y-L Chen, C-C Lin, C-Y Chen, C-Y Wang, H-L Chao, C-S Chen & M-D Lai. (2013) An HDAC inhibitor enhances cancer therapeutic efficiency of RNA polymerase III promoter-driven IDO shRNA. Cancer Gene Therapy 20:6, pages 351-357.
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Alison Gjidoda & R. William Henry. (2013) RNA polymerase III repression by the retinoblastoma tumor suppressor protein. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:3-4, pages 385-392.
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Tharakeswari Selvakumar, Alison Gjidoda, Stacy L. Hovde & R. William Henry. (2012) Regulation of Human RNA Polymerase III Transcription by DNMT1 and DNMT3a DNA Methyltransferases. Journal of Biological Chemistry 287:10, pages 7039-7050.
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Robert J. White. (2011) Transcription by RNA polymerase III: more complex than we thought. Nature Reviews Genetics 12:7, pages 459-463.
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Stephanie Cabarcas & Laura Schramm. (2011) RNA polymerase III transcription in cancer: the BRF2 connection. Molecular Cancer 10:1, pages 47.
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Dimitris Athineos, Lynne Marshall & Robert J White. (2010) Regulation of TFIIIB during F9 cell differentiation. BMC Molecular Biology 11:1.
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Sandhya Payankaulam, Li M. Li & David N. Arnosti. (2010) Transcriptional Repression: Conserved and Evolved Features. Current Biology 20:17, pages R764-R771.
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Zarmik Moqtaderi, Jie Wang, Debasish Raha, Robert J White, Michael Snyder, Zhiping Weng & Kevin Struhl. (2010) Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells. Nature Structural & Molecular Biology 17:5, pages 635-640.
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Padmaja Gade, Ashish K. Singh, Sanjit K. Roy, Sekhar P. Reddy & Dhananjaya V. Kalvakolanu. (2009) Down-regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cells . International Journal of Cancer 125:7, pages 1566-1574.
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Shuping Zhong and & Deborah L. Johnson. (2009) The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits. Proceedings of the National Academy of Sciences 106:31, pages 12682-12687.
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Simon W Rabkin & Shaun S Klassen. (2009) Jumonji is a potential regulatory factor mediating nitric oxide-induced modulation of cardiac hypertrophy. Journal of Cardiovascular Medicine 10:2, pages 206-211.
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Lynne Marshall & Robert J. White. (2008) Non-coding RNA production by RNA polymerase III is implicated in cancer. Nature Reviews Cancer 8:12, pages 911-914.
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Robert J. White. (2008) RNA polymerases I and III, non-coding RNAs and cancer. Trends in Genetics 24:12, pages 622-629.
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Sandra A.S. Johnson, Louis Dubeau & Deborah L. Johnson. (2008) Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation*. Journal of Biological Chemistry 283:28, pages 19184-19191.
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N. S. Kenneth, L. Marshall & R. J. White. (2008) Recruitment of RNA polymerase III in vivo. Nucleic Acids Research 36:11, pages 3757-3764.
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Ekaterini AngelisAlejandro GarciaShing S. ChanKatja Schenke-LaylandShuxen RenSarah J. GoodfellowMaria C. JordanKenneth P. RoosRobert J. WhiteW. Robb MacLellan. (2008) A Cyclin D2–Rb Pathway Regulates Cardiac Myocyte Size and RNA Polymerase III After Biomechanical Stress in Adult Myocardium. Circulation Research 102:10, pages 1222-1229.
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Sarah J. Goodfellow, Emma L. Graham, Theodoros Kantidakis, Lynne Marshall, Beverly A. Coppins, Danuta Oficjalska-Pham, Matthieu Gérard, Olivier Lefebvre & Robert J. White. (2008) Regulation of RNA Polymerase III Transcription by Maf1 in Mammalian Cells. Journal of Molecular Biology 378:3, pages 481-491.
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Niall S. KennethBen A. RamsbottomNatividad Gomez-RomanLynne Marshall, Philip A. Cole & Robert J. White. (2007) TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. Proceedings of the National Academy of Sciences 104:38, pages 14917-14922.
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Sébastien Lageix, Olivier Catrice, Jean-Marc Deragon, Bruno Gronenborn, Thierry Pélissier & Bertha Cecilia Ramírez. (2007) The Nanovirus-Encoded Clink Protein Affects Plant Cell Cycle Regulation through Interaction with the Retinoblastoma-Related Protein. Journal of Virology 81:8, pages 4177-4185.
Crossref
Jaime H. Reina, Teldja N. Azzouz & Nouria Hernandez. (2006) Maf1, a New Player in the Regulation of Human RNA Polymerase III Transcription. PLoS ONE 1:1, pages e134.
Crossref
Zoë A. Felton-Edkins, Alexander Kondrashov, Dimitra Karali, Jennifer A. Fairley, Christopher W. Dawson, John R. Arrand, Lawrence S. Young & Robert J. White. (2006) Epstein-Barr Virus Induces Cellular Transcription Factors to Allow Active Expression of EBER Genes by RNA Polymerase III. Journal of Biological Chemistry 281:45, pages 33871-33880.
Crossref
Danuta Oficjalska-Pham, Olivier Harismendy, Wieslaw J. Smagowicz, Anne Gonzalez de Peredo, Magdalena Boguta, André Sentenac & Olivier Lefebvre. (2006) General Repression of RNA Polymerase III Transcription Is Triggered by Protein Phosphatase Type 2A-Mediated Dephosphorylation of Maf1. Molecular Cell 22:5, pages 623-632.
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Sarah J Goodfellow, Fiona Innes, Louise E Derblay, W Robb MacLellan, Pamela H Scott & Robert J White. (2006) Regulation of RNA polymerase III transcription during hypertrophic growth. The EMBO Journal 25:7, pages 1522-1533.
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Jennifer A. Fairley, Theodoros Kantidakis, Niall S. Kenneth, Robert V. Intine, Richard J. Maraia & Robert J. White. (2005) Human La is found at RNA polymerase III-transcribed genes in vivo . Proceedings of the National Academy of Sciences 102:51, pages 18350-18355.
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Claus Christensen & Per Guldberg. (2005) Growth factors rescue cutaneous melanoma cells from apoptosis induced by knockdown of mutated (V600E) B-RAF. Oncogene 24:41, pages 6292-6302.
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Robert J. White. (2005) RNA polymerases I and III, growth control and cancer. Nature Reviews Molecular Cell Biology 6:1, pages 69-78.
Crossref
E. MaugerP.H. Scott. (2004) Mitogenic stimulation of transcription by RNA polymerase III. Biochemical Society Transactions 32:6, pages 976-977.
Crossref
Robert J White. (2004) RNA polymerase III transcription and cancer. Oncogene 23:18, pages 3208-3216.
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R.J White. (2004) RNA polymerase III transcription—a battleground for tumour suppressors and oncogenes. European Journal of Cancer 40:1, pages 21-27.
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Davide Ruggero & Pier Paolo Pandolfi. (2003) Does the ribosome translate cancer?. Nature Reviews Cancer 3:3, pages 179-192.
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Zoë A. Felton-Edkins & Robert J. White. (2002) Multiple Mechanisms Contribute to the Activation of RNA Polymerase III Transcription in Cells Transformed by Papovaviruses. Journal of Biological Chemistry 277:50, pages 48182-48191.
Crossref
Torsten Stein, Diane Crighton, Lorna J Warnock, Jo Milner & Robert J White. (2002) Several regions of p53 are involved in repression of RNA polymerase III transcription. Oncogene 21:36, pages 5540-5547.
Crossref
Torsten Stein, Diane Crighton, John M Boyle, Jennifer M Varley & Robert J White. (2002) RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome. Oncogene 21:19, pages 2961-2970.
Crossref
Daniel J. Riley & Wen-Hwa Lee. 2002. Tumor Suppressing Viruses, Genes, and Drugs. Tumor Suppressing Viruses, Genes, and Drugs 97 122 .
Sigrun Smola-Hess & Herbert J. Pfister. 2002. Structure-Function Relationships of Human Pathogenic Viruses. Structure-Function Relationships of Human Pathogenic Viruses 431 461 .
E.Peter Geiduschek & George A Kassavetis. (2001) The RNA polymerase III transcription apparatus11Edited by P. E. Wright. Journal of Molecular Biology 310:1, pages 1-26.
Crossref

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