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Transcriptional Regulation

The Orphan Nuclear Receptor SHP Utilizes Conserved LXXLL-Related Motifs for Interactions with Ligand-Activated Estrogen Receptors

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Pages 1124-1133 | Received 16 Jul 1999, Accepted 11 Nov 1999, Published online: 28 Mar 2023

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Antonio Macchiarulo, Giovanni Rizzo, Gabriele Costantino, Stefano Fiorucci & Roberto Pellicciari. (2006) Unveiling hidden features of orphan nuclear receptors: The case of the small heterodimer partner (SHP). Journal of Molecular Graphics and Modelling 24:5, pages 362-372.
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Kristina Loinder & Mats Söderström. (2005) An LXXLL motif in nuclear receptor corepressor mediates ligand-induced repression of the thyroid stimulating hormone-β gene. The Journal of Steroid Biochemistry and Molecular Biology 97:4, pages 322-327.
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Li Wang, Jun Liu, Pradip Saha, Jiansheng Huang, Lawrence Chan, Bruce Spiegelman & David D. Moore. (2005) The orphan nuclear receptor SHP regulates PGC-1α expression and energy production in brown adipocytes. Cell Metabolism 2:4, pages 227-238.
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Konstantinos Boulias, Nitsa Katrakili, Krister Bamberg, Peter Underhill, Andy Greenfield & Iannis Talianidis. (2005) Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. The EMBO Journal 24:14, pages 2624-2633.
Crossref
Yong Li, Mihwa Choi, Kelly Suino, Amanda Kovach, Jennifer Daugherty, Steven A. Kliewer & H. Eric Xu. (2005) Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner. Proceedings of the National Academy of Sciences 102:27, pages 9505-9510.
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Liang Wang, Cheng-Lung Hsu & Chawnshang Chang. (2005) Androgen receptor corepressors: An overview. The Prostate 63:2, pages 117-130.
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Myeong Goo YeoYoung-Gun YooHueng-Sik ChoiYoungmi Kim Pak & Mi-Ock Lee. (2005) Negative Cross-Talk between Nur77 and Small Heterodimer Partner and Its Role in Apoptotic Cell Death of Hepatoma Cells. Molecular Endocrinology 19:4, pages 950-963.
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Jyrki J. Eloranta & Gerd A. Kullak-Ublick. (2005) Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. Archives of Biochemistry and Biophysics 433:2, pages 397-412.
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J. J. Eloranta & G. A. Kullak-Ublick. 2005. Bile Acid Biology and its Therapeutic Implications. Bile Acid Biology and its Therapeutic Implications 107 117 .
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Eiko KANAYA, Takuma SHIRAKI & Hisato JINGAMI. (2004) The nuclear bile acid receptor FXR is activated by PGC-1α in a ligand-dependent manner. Biochemical Journal 382:3, pages 913-921.
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Anita K. Iyer & Edward R.B. McCabe. (2004) Molecular mechanisms of DAX1 action. Molecular Genetics and Metabolism 83:1-2, pages 60-73.
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Han-Jong Kim, Joon-Young Kim, Ju-Youn Kim, Sang-Kyu Park, Ji-Ho Seo, Jae Bum Kim, In-Kyu Lee, Kyung-Sup Kim & Hueng-Sik Choi. (2004) Differential Regulation of Human and Mouse Orphan Nuclear Receptor Small Heterodimer Partner Promoter by Sterol Regulatory Element Binding Protein-1. Journal of Biological Chemistry 279:27, pages 28122-28131.
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Jamie M.R. Moore, Sarah J. Galicia, Andrea C. McReynolds, Ngoc-Ha Nguyen, Thomas S. Scanlan & R. Kiplin Guy. (2004) Quantitative Proteomics of the Thyroid Hormone Receptor-Coregulator Interactions. Journal of Biological Chemistry 279:26, pages 27584-27590.
Crossref
Yun-Yong Park, Han-Jong Kim, Joon-Young Kim, Mi-Young Kim, Kwang-Hoon Song, Ki Cheol Park, Kang-Yeol Yu, Minho Shong, Kyoung-Hee Kim & Hueng-Sik Choi. (2004) Differential Role of the Loop Region between Helices H6 and H7 within the Orphan Nuclear Receptors Small Heterodimer Partner and DAX-1. Molecular Endocrinology 18:5, pages 1082-1095.
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Joon-Young Kim, Khoi Chu, Han-Jong Kim, Hyun-A Seong, Ki-Cheol Park, Sabyasachi Sanyal, Jun Takeda, Hyunjung Ha, Minho Shong, Ming-Jer Tsai & Hueng-Sik Choi. (2004) Orphan Nuclear Receptor Small Heterodimer Partner, a Novel Corepressor for a Basic Helix-Loop-Helix Transcription Factor BETA2/NeuroD. Molecular Endocrinology 18:4, pages 776-790.
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Zhengdong Zhang, Paula E. Burch, Austin J. Cooney, Rainer B. Lanz, Fred A. Pereira, Jiaqian Wu, Richard A. Gibbs, George Weinstock & David A. Wheeler. (2004) Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome. Genome Research 14:4, pages 580-590.
Crossref
Martin L. Privalsky. (2004) The Role of Corepressors in Transcriptional Regulation by Nuclear Hormone Receptors. Annual Review of Physiology 66:1, pages 315-360.
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Yangjin BaeJongsook Kim KemperByron Kemper. (2004) Repression of CAR-Mediated Transactivation of CYP2B Genes by the Orphan Nuclear Receptor, Short Heterodimer Partner (SHP) . DNA and Cell Biology 23:2, pages 81-91.
Crossref
Ying Zhang & Maria L Dufau. 2004. Nuclear Receptor Coregulators. Nuclear Receptor Coregulators 1 48 .
GARY M. KAMMER. 2004. Principles of Gender-Specific Medicine. Principles of Gender-Specific Medicine 1082 1092 .
J. M. Pascussi, Z. Dvorák, S. Gerbal-Chaloin, E. Assenat, L. Drocourt, P. Maurel & M. J. Vilarem. 2004. Transcription Factors. Transcription Factors 409 435 .
Jennifer E. Fox, Hong Liu & V. Craig Jordan. 2004. Principles of Molecular Oncology. Principles of Molecular Oncology 317 358 .
Shinta Cheng & Steven P. Balk. 2004. Signal Transduction in Cancer. Signal Transduction in Cancer 293 318 .
David E. Scott & Michael Bergevin. (2004) Fine structural correlates of the choroid plexus of the lateral cerebral ventricle of the human fetal brain. The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology.
Crossref
Li Wang, Yunqing Han, Chang-Soo Kim, Yoon-Kwang Lee & David D. Moore. (2003) Resistance of SHP-null Mice to Bile Acid-induced Liver Damage. Journal of Biological Chemistry 278:45, pages 44475-44481.
Crossref
Vicky Y. Lin, Eileen M. Resnick & Margaret A. Shupnik. (2003) Truncated Estrogen Receptor Product-1 Stimulates Estrogen Receptor α Transcriptional Activity by Titration of Repressor Proteins. Journal of Biological Chemistry 278:40, pages 38125-38131.
Crossref
KehDih Lai, Douglas C. Harnish & Mark J. Evans. (2003) Estrogen Receptor α Regulates Expression of the Orphan Receptor Small Heterodimer Partner. Journal of Biological Chemistry 278:38, pages 36418-36429.
Crossref
Elisabeth Fayard, Kristina Schoonjans, Jean-Sébastien Annicotte & Johan Auwerx. (2003) Liver Receptor Homolog 1 Controls the Expression of Carboxyl Ester Lipase. Journal of Biological Chemistry 278:37, pages 35725-35731.
Crossref
Elisabeth Jisa & Alois Jungbauer. (2003) Kinetic analysis of estrogen receptor homo- and heterodimerization in vitro. The Journal of Steroid Biochemistry and Molecular Biology 84:2-3, pages 141-148.
Crossref
Astrid Kosters, Milan Jirsa & Albert K Groen. (2003) Genetic background of cholesterol gallstone disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1637:1, pages 1-19.
Crossref
Yoon-Kwang Lee & David D. Moore. 2003. Nuclear Receptors. Nuclear Receptors 152 159 .
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Crossref
Karine Steketee, Cor A Berrevoets, Hendrikus J. Dubbink, Paul Doesburg, Remko Hersmus, Albert O. Brinkmann & Jan Trapman. (2002) Amino acids 3-13 and amino acids in and flanking the 23 FxxLF 27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor . European Journal of Biochemistry 269:23, pages 5780-5791.
Crossref
Luc Swevers, Kenichi Ito & Kostas Iatrou. (2002) The BmE75 Nuclear Receptors Function as Dominant Repressors of the Nuclear Receptor BmHR3A. Journal of Biological Chemistry 277:44, pages 41637-41644.
Crossref
Carole Brendel, Kristina Schoonjans, Oronza A. Botrugno, Eckardt Treuter & Johan Auwerx. (2002) The Small Heterodimer Partner Interacts with the Liver X Receptor α and Represses Its Transcriptional Activity. Molecular Endocrinology 16:9, pages 2065-2076.
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De-Shou Wang, Tohru Kobayashi, Balasubramanian Senthilkumaran, Fumie Sakai, Cheni Chery Sudhakumari, Taiga Suzuki, Michiyasu Yoshikuni, Masaru Matsuda, Ken-ichirou Morohashi & Yoshitaka Nagahama. (2002) Molecular cloning of DAX1 and SHP cDNAs and their expression patterns in the Nile tilapia, Oreochromis niloticus. Biochemical and Biophysical Research Communications 297:3, pages 632-640.
Crossref
Rachel Schiff & Suzanne Fuqua. 2002. Breast Cancer. Breast Cancer 149 186 .
Li Wang, Yoon-Kwang Lee, Donnie Bundman, Yunqing Han, Sundararajah Thevananther, Chang-Soo Kim, Steven S Chua, Ping Wei, Richard A Heyman, Michael Karin & David D Moore. (2002) Redundant Pathways for Negative Feedback Regulation of Bile Acid Production. Developmental Cell 2:6, pages 721-731.
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Jonathan M. Harris, Patrick Lau, Shen Liang Chen & George E. O. Muscat. (2002) Characterization of the Retinoid Orphan-Related Receptor-α Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription. Molecular Endocrinology 16:5, pages 998-1012.
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Crossref
Yoon-Kwang Lee & David D. Moore. (2002) Dual Mechanisms for Repression of the Monomeric Orphan Receptor Liver Receptor Homologous Protein-1 by the Orphan Small Heterodimer Partner. Journal of Biological Chemistry 277:4, pages 2463-2467.
Crossref
Hitoshi Nishizawa, Kazuya Yamagata, Iichiro Shimomura, Masahiko Takahashi, Hiroshi Kuriyama, Ken Kishida, Kikuko Hotta, Hiroyuki Nagaretani, Norikazu Maeda, Morihiro Matsuda, Shinji Kihara, Tadashi Nakamura, Hidekazu Nishigori, Hideaki Tomura, David D. Moore, Jun Takeda, Tohru Funahashi & Yuji Matsuzawa. (2002) Small Heterodimer Partner, an Orphan Nuclear Receptor, Augments Peroxisome Proliferator-activated Receptor γ Transactivation. Journal of Biological Chemistry 277:2, pages 1586-1592.
Crossref
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 445 452 .
G. Ozisik, J. C. Achermann, J. J. Meeks & J. L. Jameson. 2002. Testicular Tangrams. Testicular Tangrams 151 171 .
Timothy T. Lu, Joyce J. Repa & David J. Mangelsdorf. (2001) Orphan Nuclear Receptors as eLiXiRs and FiXeRs of Sterol Metabolism. Journal of Biological Chemistry 276:41, pages 37735-37738.
Crossref
Jonathan G Moggs & George Orphanides. (2001) Estrogen receptors: orchestrators of pleiotropic cellular responses. EMBO reports 2:9, pages 775-781.
Crossref
Anette Wärnmark, Tova Almlöf, Jörg Leers, Jan-Åke Gustafsson & Eckardt Treuter. (2001) Differential Recruitment of the Mammalian Mediator Subunit TRAP220 by Estrogen Receptors ERα and ERβ. Journal of Biological Chemistry 276:26, pages 23397-23404.
Crossref
Carolyn M. Klinge, Sarah C. Jernigan, Kelly E. Risinger, Jennie E. Lee, Valentyn V. Tyulmenkov, K.Cameron Falkner & Russell A. Prough. (2001) Short Heterodimer Partner (SHP) Orphan Nuclear Receptor Inhibits the Transcriptional Activity of Aryl Hydrocarbon Receptor (AHR)/AHR Nuclear Translocator (ARNT). Archives of Biochemistry and Biophysics 390:1, pages 64-70.
Crossref
Altaf Kassam, John P. Capone & Richard A. Rachubinski. (2001) The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor α-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal β-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase. Molecular and Cellular Endocrinology 176:1-2, pages 49-56.
Crossref
Katarina PetterssonJan-Åke Gustafsson. (2001) Role of Estrogen Receptor Beta in Estrogen Action. Annual Review of Physiology 63:1, pages 165-192.
Crossref
Qi Wang, JinHua Lu & E.L. Yong. (2001) Ligand- and Coactivator-mediated Transactivation Function (AF2) of the Androgen Receptor Ligand-binding Domain Is Inhibited by the Cognate Hinge Region. Journal of Biological Chemistry 276:10, pages 7493-7499.
Crossref
Stefan Nilsson, Sari Mäkelä, Eckardt Treuter, Michel Tujague, Jane Thomsen, Göran Andersson, Eva Enmark, Katarina Pettersson, Margaret Warner & Jan-Åke Gustafsson. (2001) Mechanisms of Estrogen Action. Physiological Reviews 81:4, pages 1535-1565.
Crossref
Hui Zhang, Jane S. Thomsen, Lotta Johansson, Jan-Åke Gustafsson & Eckardt Treuter. (2000) DAX-1 Functions as an LXXLL-containing Corepressor for Activated Estrogen Receptors. Journal of Biological Chemistry 275:51, pages 39855-39859.
Crossref
Andrew A. Bogan, Qing Dallas-Yang, Michael D. RuseJrJr, Yutaka Maeda, Guoqiang Jiang, Luviminda Nepomuceno, Thomas S. Scanlan, Fred E. Cohen & Frances M. Sladek. (2000) Analysis of protein dimerization and ligand binding of orphan receptor HNF4α. Journal of Molecular Biology 302:4, pages 831-851.
Crossref

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