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Molecular and Cellular Biology Volume 20, 2000 - Issue 9
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Cell Growth and Development

Mechanism of Suppression of the Raf/MEK/Extracellular Signal-Regulated Kinase Pathway by the Raf Kinase Inhibitor Protein

Kam Yeung1 Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island02912
,
Petra Janosch2 Beatson Institute for Cancer Research, CRC Beatson Laboratories, Bearsden, GlasgowG61 1BD, United Kingdom
,
Brian McFerran2 Beatson Institute for Cancer Research, CRC Beatson Laboratories, Bearsden, GlasgowG61 1BD, United Kingdom
,
David W. Rose3 Department of Medicine and Whittier Diabetes Program, University of California San Diego, La Jolla, California92093-0673
,
Harald Mischak4 Abt. Nephrologie, Medizinische Hochschule Hannover, D-0625Hannover, Germany
,
John M. Sedivy1 Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island02912Correspondence[email protected]
&
Walter Kolch2 Beatson Institute for Cancer Research, CRC Beatson Laboratories, Bearsden, GlasgowG61 1BD, United KingdomCorrespondence[email protected]
 show all
Pages 3079-3085 | Received 07 Oct 1999, Accepted 18 Feb 2000, Published online: 27 Mar 2023

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Yi Wen, Lingxiu Fan, Lili Pang, Tingting Zhao, Ruonan Li, Ying Zhang, Liye Zhang & Wei Yang. (2022) NeiyiKangfu tablets control the progression of endometriosis through inhibiting RAF/MEK/ERK signal pathway by targeting RKIP. Gynecological Endocrinology 38:12, pages 1136-1146.
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Chuanling Wu, Kai Xu, Wenqiang Liu, Anqi Liu, Huimin Liang, Qunwang Li, Zhen Feng, Yang Yang, Jiayuan Ding, Tianyi Zhang, Yingxue Liu, Xuezheng Liu & Zhongfu Zuo. (2022) Protective Effect of Raf-1 Kinase Inhibitory Protein on Diabetic Retinal Neurodegeneration through P38-MAPK Pathway. Current Eye Research 47:1, pages 135-142.
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Fabienne Saab, Sylvain Routier, Jean-Yves Mérour, Valérie Bénéteau & Françoise Schoentgen. (2010) Comparison of the efficiencies of two TR-FRET methods to detect in vitro natural and synthesized inhibitors of the Raf/MEK/ERK signaling pathway. International Journal of High Throughput Screening 1, pages 81-98.
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Lingchun Zeng, Akira Imamoto & Marsha Rich Rosner. (2008) Raf kinase inhibitory protein (RKIP): A physiological regulator and future therapeutic target. Expert Opinion on Therapeutic Targets 12:10, pages 1275-1287.
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Anton Yuryev. (2008) In silico pathway analysis: the final frontier towards completely rational drug design. Expert Opinion on Drug Discovery 3:8, pages 867-876.
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M. J. Robinson, S. Beinke, A. Kouroumalis, P. N. Tsichlis & S. C. Ley. (2007) Phosphorylation of TPL-2 on Serine 400 Is Essential for Lipopolysaccharide Activation of Extracellular Signal-Regulated Kinase in Macrophages. Molecular and Cellular Biology 27:21, pages 7355-7364.
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Linda K. Rushworth, Alison D. Hindley, Eric O'Neill & Walter Kolch. (2006) Regulation and Role of Raf-1/B-Raf Heterodimerization. Molecular and Cellular Biology 26:6, pages 2262-2272.
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S. Beinke, J. Deka, V. Lang, M. P. Belich, P. A. Walker, S. Howell, S. J. Smerdon, S. J. Gamblin & S. C. Ley. (2003) NF-κB1 p105 Negatively Regulates TPL-2 MEK Kinase Activity. Molecular and Cellular Biology 23:14, pages 4739-4752.
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Amardeep S. Dhillon, Sharon Meikle, Carole Peyssonnaux, Joan Grindlay, Christian Kaiser, Helge Steen, Peter E. Shaw, Harald Mischak, Alain Eychène & Walter Kolch. (2003) A Raf-1 Mutant That Dissociates MEK/Extracellular Signal-Regulated Kinase Activation from Malignant Transformation and Differentiation but Not Proliferation. Molecular and Cellular Biology 23:6, pages 1983-1993.
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Kam C. Yeung, David W. Rose, Amardeep S. Dhillon, Diane Yaros, Marcus Gustafsson, Devasis Chatterjee, Brian McFerran, James Wyche, Walter Kolch & John M. Sedivy. (2001) Raf Kinase Inhibitor Protein Interacts with NF-κB-Inducing Kinase and TAK1 and Inhibits NF-κB Activation. Molecular and Cellular Biology 21:21, pages 7207-7217.
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Swati Gupta, Rina Plattner, Channing J. Der & Eric J. Stanbridge. (2000) Dissection of Ras-Dependent Signaling Pathways Controlling Aggressive Tumor Growth of Human Fibrosarcoma Cells: Evidence for a Potential Novel Pathway. Molecular and Cellular Biology 20:24, pages 9294-9306.
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