14
Views
63
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Methylation of the Cyclin A1 Promoter Correlates with Gene Silencing in Somatic Cell Lines, while Tissue-Specific Expression of Cyclin A1 Is Methylation Independent

, , , , , , , & show all
Pages 3316-3329 | Received 29 Jun 1999, Accepted 26 Jan 2000, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Carsten Müller-Tidow, Ping Ji, Sven Diederichs, Jenny Potratz, Nicole Bäumer, Gabriele Köhler, Thomas Cauvet, Chunaram Choudary, Tiffany van der Meer, Wan-Yu Iris Chan, Conrad Nieduszynski, William H. Colledge, Mark Carrington, H. Phillip Koeffler, Anja Restle, Lisa Wiesmüller, Joëlle Sobczak-Thépot, Wolfgang E. Berdel & Hubert Serve. (2004) The Cyclin A1-CDK2 Complex Regulates DNA Double-Strand Break Repair. Molecular and Cellular Biology 24:20, pages 8917-8928.
Read now
Carsten Müller-Tidow, Björn Steffen, Thomas Cauvet, Lara Tickenbrock, Ping Ji, Sven Diederichs, Bülent Sargin, Gabriele Köhler, Matthias Stelljes, Elena Puccetti, Martin Ruthardt, Sven deVos, Scott W. Hiebert, H. Phillip Koeffler, Wolfgang E. Berdel & Hubert Serve. (2004) Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells. Molecular and Cellular Biology 24:7, pages 2890-2904.
Read now

Articles from other publishers (61)

Min Chen, Shizhao Li, Vinodh Srinivasasainagendra, Manvi Sharma, Zhenhai Li, Hemant Tiwari, Trygve O Tollefsbol & Yuanyuan Li. (2022) Maternal soybean genistein on prevention of later-life breast cancer through inherited epigenetic regulations. Carcinogenesis 43:3, pages 190-202.
Crossref
Zlatina I. Gospodinova, Istvan Zupkó, Noémi Bózsity, Vasilissa I. Manova, Mariyana S. Georgieva, Svetla J. Todinova, Stefka G. Taneva, Imre Ocsovszki & Maria E. Krasteva. (2021) Cotinus coggygria Scop. induces cell cycle arrest, apoptosis, genotoxic effects, thermodynamic and epigenetic events in MCF7 breast cancer cells . Zeitschrift für Naturforschung C 76:3-4, pages 129-140.
Crossref
M. Krasteva, Y. Koycheva, T. Taseva & S. Simeonova. (2020) Changes in the Expression of DNA Methylation Related Genes in Leukocytes of Persons with Alcohol and Drug Dependence. Acta Medica Bulgarica 47:4, pages 11-17.
Crossref
Xiaoting He, Suqing Li, Weihong Shi, Qingfeng Lin, Jian Ma, Yang Liu, Tingting Feng & Xiufeng Cao. (2019) Cyclin A1 is associated with poor prognosis in oesophageal squamous cell carcinoma. Oncology Letters.
Crossref
Deepti L. Kumar, Priya L. Kumar & Paul F. James. (2016) Methylation-dependent and independent regulatory regions in the Na,K-ATPase alpha4 (Atp1a4) gene may impact its testis-specific expression. Gene 575:2, pages 339-352.
Crossref
Yan Liu, Yue Huang & Guo-Zhang Zhu. (2013) Cyclin A1 is a transcriptional target of PITX2 and overexpressed in papillary thyroid carcinoma. Molecular and Cellular Biochemistry 384:1-2, pages 221-227.
Crossref
Anna Pakula, Joanna Schneider, Jürgen Janke, Ute Zacharias, Herbert Schulz, Norbert Hübner, Anja Mähler, Andreas Spuler, Simone Spuler, Pierre Carlier & Michael Boschmann. (2013) Altered Expression of Cyclin A 1 In Muscle of Patients with Facioscapulohumeral Muscle Dystrophy (FSHD-1). PLoS ONE 8:9, pages e73573.
Crossref
Rajakishore Mishra. (2013) Cell cycle-regulatory cyclins and their deregulation in oral cancer. Oral Oncology 49:6, pages 475-481.
Crossref
Sunil K. Panigrahi, Ana Vasileva & Debra J. Wolgemuth. (2012) Sp1 Transcription Factor and GATA1 cis-Acting Elements Modulate Testis-Specific Expression of Mouse Cyclin A1. PLoS ONE 7:10, pages e47862.
Crossref
M Brait, L Maldonado, S Begum, M Loyo, D Wehle, F F Tavora, L H J Looijenga, J Kowalski, Z Zhang, E Rosenbaum, S Halachmi, G J Netto & M O Hoque. (2011) DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma. British Journal of Cancer 106:2, pages 414-423.
Crossref
A. G. Abdou, M. A. Hammam, A. G. A. Farag, S. Farouk & M. Fawzy. (2011) Immunohistochemical expression of cyclin A in testicular biopsies of fertile and infertile men: correlation with the morphometry of seminiferous tubules. Andrologia 43:1, pages 57-64.
Crossref
Janine M LaSalleDag H Yasui. (2009) Evolving role of MeCP2 in Rett syndrome and autism. Epigenomics 1:1, pages 119-130.
Crossref
Takahiro Haraguchi, Tomomoto Ishikawa, Kohei Yamaguchi & Masato Fujisawa. (2009) Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia. Fertility and Sterility 91:4, pages 1424-1426.
Crossref
Lara Tickenbrock, Sina Hehn, Bülent Sargin, Georg Evers, Pavankumar Reddy NG, Chunaram Choudhary, Wolfgang E. Berdel, Carsten Müller-Tidow & Hubert Serve. (2008) Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia. International Journal of Hematology 88:2, pages 174-180.
Crossref
Qingsheng Yu & Ji Wu. (2008) Involvement of cyclins in mammalian spermatogenesis. Molecular and Cellular Biochemistry 315:1-2, pages 17-24.
Crossref
Dag H. Yasui, Sailaja Peddada, Mark C. Bieda, Roxanne O. Vallero, Amber Hogart, Raman P. Nagarajan, Karen N. Thatcher, Peggy J. Farnham & Janine M. LaSalle. (2007) Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proceedings of the National Academy of Sciences 104:49, pages 19416-19421.
Crossref
ChaRandle Jordan, Hong Hua Li, Helen C Kwan & Uta Francke. (2007) Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets. BMC Medical Genetics 8:1.
Crossref
Shuchi AgrawalWolf-Karsten HofmannNicola TidowMathias Ehrich, Dirk van den Boom, Steffen KoschmiederWolfgang E. BerdelHubert ServeCarsten Müller-Tidow. (2007) The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. Blood 109:9, pages 3895-3905.
Crossref
Shuchi Agrawal, Matthias Unterberg, Steffen Koschmieder, Udo zur Stadt, Uta Brunnberg, Walter Verbeek, Thomas Büchner, Wolfgang E. Berdel, Hubert Serve & Carsten Müller-Tidow. (2007) DNA Methylation of Tumor Suppressor Genes in Clinical Remission Predicts the Relapse Risk in Acute Myeloid Leukemia. Cancer Research 67:3, pages 1370-1377.
Crossref
Nakarin Kitkumthorn, Pattamawadee Yanatatsanajit, Sorapop Kiatpongsan, Chureerat Phokaew, Surang Triratanachat, Prasert Trivijitsilp, Wichai Termrungruanglert, Damrong Tresukosol, Somchai Niruthisard & Apiwat Mutirangura. (2006) Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer. BMC Cancer 6:1.
Crossref
ChaRandle Jordan & Uta Francke. (2006) Ube3a expression is not altered in Mecp2 mutant mice. Human Molecular Genetics 15:14, pages 2210-2215.
Crossref
Lara Tickenbrock, Joachim Schwäble, Anke Strey, Bülent Sargin, Sina Hehn, Marion Baas, Chunaram Choudhary, Volker Gerke, Wolfgang E Berdel, Carsten Müller-Tidow & Hubert Serve. (2006) Wnt signaling regulates transendothelial migration of monocytes. Journal of Leukocyte Biology 79:6, pages 1306-1313.
Crossref
Giorgio Cavallini. (2006) Male idiopathic oligoasthenoteratozoospermia. Asian Journal of Andrology 8:2, pages 143-157.
Crossref
Jun Ishiko, Masao Mizuki, Itaru Matsumura, Hirohiko Shibayama, Hiroyuki Sugahara, Glen Scholz, Hubert Serve & Yuzuru Kanakura. (2005) Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant. Oncogene 24:55, pages 8144-8153.
Crossref
Markus Böhm, Mareike Eickelmann, Zhuo Li, Stefan W. Schneider, Vinzenz Oji, Sven Diederichs, Gregory S. Barsh, Annika Vogt, Karola Stieler, Ulrike Blume-Peytavi & Thomas A. Luger. (2005) Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells. Endocrinology 146:11, pages 4635-4646.
Crossref
Sven Diederichs, Nicole Bäumer, Nikolaus Schultz, F. Kent Hamra, Mark G. Schrader, Marie-Luise Sandstede, Wolfgang E. Berdel, Hubert Serve & Carsten Müller-Tidow. (2005) Expression patterns of mitotic and meiotic cell cycle regulators in testicular cancer and development. International Journal of Cancer 116:2, pages 207-217.
Crossref
Masanobu Shoji, Shinichiro Chuma, Kayo Yoshida, Takashi Morita & Norio Nakatsuji. (2005) RNA interference during spermatogenesis in mice. Developmental Biology 282:2, pages 524-534.
Crossref
Lara TickenbrockJoachim SchwäbleMarkus WiedehageBjörn SteffenBülent SarginChunaram ChoudharyChristian BrandtsWolfgang E. BerdelCarsten Müller-TidowHubert Serve. (2005) Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction. Blood 105:9, pages 3699-3706.
Crossref
S. V. Salozhin, E. B. Prokhorchuk & G. P. Georgiev. (2005) Methylation of DNA — One of the Major Epigenetic Markers. Biochemistry (Moscow) 70:5, pages 525-532.
Crossref
Joachim SchwäbleChunaram ChoudharyChristian ThiedeLara TickenbrockBülent SarginClaudia SteurMaike RehageAnnika RudatChristian BrandtsWolfgang E. BerdelCarsten Müller-TidowHubert Serve. (2005) RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation. Blood 105:5, pages 2107-2114.
Crossref
James A. MacLeanIIII & Miles F. Wilkinson. 2005. 131 197 .
Jennifer Worch, Lara Tickenbrock, Joachim Schwäble, Björn Steffen, Thomas Cauvet, Barbara Mlody, Horst Buerger, H Phillip Koeffler, Wolfgang E Berdel, Hubert Serve & Carsten Müller-Tidow. (2004) The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARα and regulates differentiation of hematopoietic cells. Oncogene 23:57, pages 9162-9172.
Crossref
Jian Yu, Hongyu Zhang, Jun Gu, Song Lin, Junhua Li, Wei Lu, Yifei Wang & Jingde Zhu. (2004) Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer 4:1.
Crossref
Takuya Noguchi, Keiji Tanimoto, Tatsushi Shimokuni, Kei Ukon, Hiroaki Tsujimoto, Masakazu Fukushima, Tsuyoshi Noguchi, Katsunobu Kawahara, Keiko Hiyama & Masahiko Nishiyama. (2004) Aberrant Methylation of DPYD Promoter, DPYD Expression, and Cellular Sensitivity to 5-Fluorouracil in Cancer Cells . Clinical Cancer Research 10:20, pages 7100-7107.
Crossref
Zhuo Li, Dieter Metze, Dorothea Nashan, Carsten Müller-Tidow, Hubert L. Serve, Christopher Poremba, Thomas A. Luger & Markus Böhm. (2004) Expression of SOCS-1, Suppressor of Cytokine Signalling-1, in Human Melanoma. Journal of Investigative Dermatology 123:4, pages 737-745.
Crossref
Karen M. Lele & Debra J. Wolgemuth. (2004) Distinct Regions of the Mouse Cyclin A1 Gene, Ccna1, Confer Male Germ-Cell Specific Expression and Enhancer Function1. Biology of Reproduction 71:4, pages 1340-1347.
Crossref
Peter H. Lapchak, Michael Melter, Soumitro Pal, Jesse A. Flaxenburg, Christopher Geehan, Markus H. Frank, Debabrata Mukhopadhyay & David M. Briscoe. (2004) CD40-induced transcriptional activation of vascular endothelial growth factor involves a 68-bp region of the promoter containing a CpG island. American Journal of Physiology-Renal Physiology 287:3, pages F512-F520.
Crossref
SangYoon Han, Wensheng Xie, Sok Ho Kim, Limin Yue & Jeff DeJong. (2004) A Short Core Promoter Drives Expression of the ALF Transcription Factor in Reproductive Tissues of Male and Female Mice1. Biology of Reproduction 71:3, pages 933-941.
Crossref
Sven Diederichs, Nicole Bäumer, Ping Ji, Stephan K. Metzelder, Gregory E. Idos, Thomas Cauvet, Wenbing Wang, Maria Möller, Sarah Pierschalski, Jörg Gromoll, Mark G. Schrader, H. Phillip Koeffler, Wolfgang E. Berdel, Hubert Serve & Carsten Müller-Tidow. (2004) Identification of Interaction Partners and Substrates of the Cyclin A1-CDK2 Complex. Journal of Biological Chemistry 279:32, pages 33727-33741.
Crossref
Nancy H. Ing, Andy M. Laughlin, Dickson D. Varner, Thomas H. WelshJr.Jr., David W. Forrest, Terry L. Blanchard & Larry Johnson. (2004) Gene Expression in the Spermatogenically Inactive “Dark” and Maturing “Light” Testicular Tissues of the Prepubertal Colt. Journal of Andrology 25:4, pages 535-544.
Crossref
Süleyman Ergün, Christian Buschmann, Jochen Heukeshoven, Kristin Dammann, Frank Schnieders, Heidrun Lauke, Fariba Chalajour, Nerbil Kilic, Wolf H. Strätling & Gerald G. Schumann. (2004) Cell Type-specific Expression of LINE-1 Open Reading Frames 1 and 2 in Fetal and Adult Human Tissues. Journal of Biological Chemistry 279:26, pages 27753-27763.
Crossref
C Müller-Tidow, S K Metzelder, H Buerger, J Packeisen, A Ganser, G Heil, K Kügler, G Adigüzel, J Schwäble, B Steffen, W-D Ludwig, A Heinecke, T Büchner, W E Berdel & H Serve. (2004) Expression of the p14ARF tumor suppressor predicts survival in acute myeloid leukemia. Leukemia 18:4, pages 720-726.
Crossref
Markus Böhm, Michael Raghunath, Cord Sunderkötter, Meinhard Schiller, Sonja Ständer, Thomas Brzoska, Thomas Cauvet, Helgi B. Schiöth, Thomas Schwarz & Thomas A. Luger. (2004) Collagen Metabolism Is a Novel Target of the Neuropeptide α-Melanocyte-stimulating Hormone. Journal of Biological Chemistry 279:8, pages 6959-6966.
Crossref
Xiao-Li Xu. (2004) Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World Journal of Gastroenterology 10:23, pages 3441.
Crossref
Janine M LaSalle. 2004. 61 86 .
H M Müller, H Fiegl, G Goebel, M M Hubalek, A Widschwendter, E Müller-Holzner, C Marth & M Widschwendter. (2003) MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status. British Journal of Cancer 89:10, pages 1934-1939.
Crossref
Jian YU, Hong Yu ZHANG, Zhen Zhong MA, Wei LU, Yi Fei WANG & Jingde ZHU. (2003) Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis. Cell Research 13:5, pages 319-333.
Crossref
Björn Steffen, Hubert Serve, Wolfgang E. Berdel, Shuchi Agrawal, Bryan Linggi, Thomas Büchner, Scott W. Hiebert & Carsten Müller-Tidow. (2003) Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia. Proceedings of the National Academy of Sciences 100:14, pages 8448-8453.
Crossref
Masao MizukiJoachim SchwäbleClaudia SteurChunaram ChoudharyShuchi AgrawalBülent SarginBjörn SteffenItaru MatsumuraYuzuru KanakuraFrank D. BöhmerCarsten Müller-TidowWolfgang E. BerdelHubert Serve. (2003) Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations. Blood 101:8, pages 3164-3173.
Crossref
Carsten Müller-Tidow, Sven Diederichs, Mark G. Schrader, Ulf Vogt, Kurt Miller, Wolfgang E. Berdel & Hubert Serve. (2003) Cyclin A1 is highly expressed in aggressive testicular germ cell tumors. Cancer Letters 190:1, pages 89-95.
Crossref
B. Steffen, M. Ruthardt, K. Becker, S. Klümpen, M. Möller, W. E. Berdel, H. Serve & C. Müller-Tidow. 2003. Acute Leukemias IX. Acute Leukemias IX 40 43 .
Karim Roder, Maria-Jesus Latasa & Hei Sook Sul. (2002) Silencing of the Mouse H-rev107 Gene Encoding a Class II Tumor Suppressor by CpG Methylation. Journal of Biological Chemistry 277:34, pages 30543-30550.
Crossref
Mark Schrader, Stuart Ravnik, Carsten Muller-Tidow, Markus Muller, Bernd Straub, Sven Diedrichs, Hubert Serve & Kurt Miller. (2002) Quantification of cyclin A1 and glyceraldehyde-3-phosphate dehydrogenase expression in testicular biopsies of infertile patients by fluorescence real-time RT-PCR. International Journal of Andrology 25:4, pages 202-209.
Crossref
Jane L Ko, Hung-Chun Chen & Horace H Loh. (2002) Differential promoter usage of mouse μ-opioid receptor gene during development. Molecular Brain Research 104:2, pages 184-193.
Crossref
Wensheng Xie, SangYoon Han, Mohammed Khan & Jeff DeJong. (2002) Regulation of ALF Gene Expression in Somatic and Male Germ Line Tissues Involves Partial and Site-specific Patterns of Methylation. Journal of Biological Chemistry 277:20, pages 17765-17774.
Crossref
Luc E.G. Rietveld, Eric Caldenhoven & Hendrik G. Stunnenberg. (2002) In vivo repression of an erythroid-specific gene by distinct corepressor complexes . The EMBO Journal 21:6, pages 1389-1397.
Crossref
Carsten Müller-TidowWenbing WangGregory E. IdosSven DiederichsRong YangCarol ReadheadWolfgang E. BerdelHubert ServeMark SavilleRoger WatsonH. Phillip Koeffler. (2001) Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function. Blood 97:7, pages 2091-2097.
Crossref
Carsten Müller-Tidow, Christina Bornemann, Sven Diederichs, Annette Westermann, Silvia Klümpen, Peijun Zuo, Wenbing Wang, Wolfgang E Berdel & Hubert Serve. (2001) Analyses of the genomic methylation status of the human cyclin A1 promoter by a novel real-time PCR-based methodology. FEBS Letters 490:1-2, pages 75-78.
Crossref
Walter Stünkel, Slimane Ait-Si-Ali, Peter L. Jones & Alan P. Wolffe. (2001) Programming the Transcriptional State of Replicating Methylated DNA. Journal of Biological Chemistry 276:23, pages 20743-20749.
Crossref
Carsten MüllerRong YangDorothy J. ParkHubert ServeWolfgang E. BerdelH. Phillip Koeffler. (2000) The aberrant fusion proteins PML-RARα and PLZF-RARα contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia. Blood 96:12, pages 3894-3899.
Crossref
Carsten MüllerRong YangDorothy J. ParkHubert ServeWolfgang E. BerdelH. Phillip Koeffler. (2000) The aberrant fusion proteins PML-RARα and PLZF-RARα contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia. Blood 96:12, pages 3894-3899.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.