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Mammalian Genetic Models with Minimal or Complex Phenotypes

Gene Disruption of Tissue Transglutaminase

Vincenzo De LaurenziIDI-IRCCS Biochemistry Lab, Department of Experimental Medicine, University Tor Vergata, Rome, Italy
&
Gerry MelinoIDI-IRCCS Biochemistry Lab, Department of Experimental Medicine, University Tor Vergata, Rome, ItalyCorrespondence[email protected]
Pages 148-155 | Received 20 Jul 2000, Accepted 28 Sep 2000, Published online: 28 Mar 2023

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Young Chan Kim, Jeonghyeon Kim, Subin Kim, Boram Bae, Ruth Lee Kim, Eui-Man Jeong, Sang-Heon Cho & Hye-Ryun Kang. (2021) Transglutaminase 2 mediates lung inflammation and remodeling by transforming growth factor beta 1 via alveolar macrophage modulation. Experimental Lung Research 47:10, pages 465-475.
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Ana-Marija Sulic, Kalle Kurppa, Tiina Rauhavirta, Katri Kaukinen & Katri Lindfors. (2015) Transglutaminase as a therapeutic target for celiac disease. Expert Opinion on Therapeutic Targets 19:3, pages 335-348.
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Kalle Kurppa, Minna Hietikko, Ana-Marija Sulic, Katri Kaukinen & Katri Lindfors. (2014) Current status of drugs in development for celiac disease. Expert Opinion on Investigational Drugs 23:8, pages 1079-1091.
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Begoña Diosdado & Cisca Wijmenga. (2005) Molecular mechanisms of the adaptive, innate and regulatory immune responses in the intestinal mucosa of celiac disease patients. Expert Review of Molecular Diagnostics 5:5, pages 681-700.
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E. Bodil Roth, Klas Sjöberg & Pål Stenberg. (2003) Biochemical and Immuno-pathological Aspects of Tissue Transglutaminase in Coeliac Disease. Autoimmunity 36:4, pages 221-226.
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Crossref
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Crossref
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Crossref
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Crossref
J H Kang, S-H Lee & S-Y Kim. (2016) Discovery of a novel target for renal cell carcinoma: transglutaminase 2. Cell Death & Disease 7:4, pages e2200-e2200.
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Crossref
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Crossref
Jia-Hau Yen, Ling-Chung Lin, Meng-Chi Chen, Zsolt Sarang, Pui-Ying Leong, I-Chang Chang, Jeng-Dong Hsu, Jiunn-Horng Chen, Yu-Fan Hsieh, Anna Pallai, Krisztina Köröskényi, Zsuzsa Szondy & Gregory J Tsay. (2015) The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1. Arthritis Research & Therapy 17:1.
Crossref
Hideki Tatsukawa, Natsumi Abe, Shintaro Ohashi & Kiyotaka Hitomi. (2015) Distribution of transglutaminase family members in mouse whole body sections. Biochemical and Biophysical Research Communications 467:4, pages 1046-1051.
Crossref
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Crossref
V D Myneni, G Melino & M T Kaartinen. (2015) Transglutaminase 2—a novel inhibitor of adipogenesis. Cell Death & Disease 6:8, pages e1868-e1868.
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Nathan BeckoucheMarine BignonVirginie LelargeThomas MathivetCathy Pichol-ThievendSarah BerndtJulie HardouinMarion GarandCorinne Ardidie-RobouantAlain BarretGerry MelinoHugues Lortat-JacobLaurent MullerCatherine MonnotStephane Germain. (2015) The interaction of heparan sulfate proteoglycans with endothelial transglutaminase-2 limits VEGF 165 -induced angiogenesis . Science Signaling 8:385.
Crossref
Inês Cardoso, Jorunn Stamnaes, Jan Terje Andersen, Gerry Melino, Rasmus Iversen & Ludvig M. Sollid. (2015) Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies. FEBS Journal 282:11, pages 2063-2075.
Crossref
Nicholas M. Plugis & Chaitan Khosla. (2015) Therapeutic approaches for celiac disease. Best Practice & Research Clinical Gastroenterology 29:3, pages 503-521.
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Harini RaghuCarolina CruzCheryl L. RewertsMalinda D. FrederickSherry Thornton, Eric S. Mullins, Jonathan G. Schoenecker, Jay L. DegenMatthew J. Flick. (2015) Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion. Blood 125:3, pages 427-437.
Crossref
Enrica Serretiello, Martina Iannaccone, Federica Titta, Nicola G. Gatta & Vittorio Gentile. (2015) Possible pathophysiological roles of transglutaminase-catalyzed reactions in the pathogenesis of human neurodegenerative diseases. AIMS Biophysics 2:4, pages 441-457.
Crossref
Soo-Youl Kim. 2015. Transglutaminases. Transglutaminases 153 170 .
Siiri E. Iismaa. 2015. Transglutaminases. Transglutaminases 83 115 .
Eui Man Jeong & In-Gyu Kim. 2015. Transglutaminases. Transglutaminases 315 331 .
Cui Cui & Mari T. Kaartinen. 2015. Transglutaminases. Transglutaminases 263 281 .
Elisabetta A. M. Verderio, Giulia Furini, Izhar W. Burhan & Timothy S. Johnson. 2015. Transglutaminases. Transglutaminases 229 262 .
Kaiser M. Bijli, Bryce G. Kanter, Mohammad Minhajuddin, Antony Leonard, Lei Xu, Fabeha Fazal & Arshad Rahman. (2014) Regulation of Endothelial Cell Inflammation and Lung Polymorphonuclear Lymphocyte Infiltration by Transglutaminase 2. Shock 42:6, pages 562-569.
Crossref
Cornelius Klöck, Zachary Herrera, Megan Albertelli & Chaitan Khosla. (2014) Discovery of Potent and Specific Dihydroisoxazole Inhibitors of Human Transglutaminase 2. Journal of Medicinal Chemistry 57:21, pages 9042-9064.
Crossref
Jin-Hee Kim, Jun Man Hong, Eui Man Jeong, Wang Jae Lee, Hang-Rae Kim, Jae Seung Kang, In-Gyu Kim & Young-il Hwang. (2014) Lack of transglutaminase 2 diminished T-cell responses in mice. Immunology 142:3, pages 506-516.
Crossref
Jin-Hee Kim, Eui Man Jeong, Young-Joo Jeong, Wang Jae Lee, Jae Seung Kang, In-Gyu Kim & Young-il Hwang. (2014) Transglutaminase 2 on the surface of dendritic cells is proposed to be involved in dendritic cell–T cell interaction. Cellular Immunology 289:1-2, pages 55-62.
Crossref
Liquan Yang, Scott Friedland, Nancy Corson & Lei Xu. (2014) GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2. Cancer Research 74:4, pages 1022-1031.
Crossref
Seung-Kee Min, Sang-Il MinEui Man Jeong, Sung-Yup Cho, Jongwon HaSang Joon KimIn-Gyu Kim. (2014) Intimal Hyperplasia in Loop-Injured Carotid Arteries Is Attenuated in Transglutaminase 2-Null Mice. Journal of Korean Medical Science 29:3, pages 363.
Crossref
Benedict Onyekachi Odii & Peter Coussons. (2014) Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family. The Scientific World Journal 2014, pages 1-13.
Crossref
Vandana Nehra, Eric V. Marietta & Joseph A. Murray. 2014. Wheat and Rice in Disease Prevention and Health. Wheat and Rice in Disease Prevention and Health 143 155 .
Eric V. Marietta, Alberto Rubio-Tapia & Joseph A. Murray. 2014. Celiac Disease. Celiac Disease 67 80 .
William Bains. (2013) Transglutaminse 2 and EGGL, the Protein Cross-Link Formed by Transglutaminse 2, As Therapeutic Targets for Disabilities of Old Age. Rejuvenation Research 16:6, pages 495-517.
Crossref
Janet F. Staab, Kausik Datta & Peter Rhee. (2013) Niche-Specific Requirement for Hyphal Wall protein 1 in Virulence of Candida albicans. PLoS ONE 8:11, pages e80842.
Crossref
Bo Mi Ku, Dae‐Seok Kim, Kyung‐Hee Kim, Byong Chul Yoo, Seok‐Hyun Kim, Young‐Dae Gong & Soo‐Youl Kim. (2013) Transglutaminase 2 inhibition found to induce p53 mediated apoptosis in renal cell carcinoma. The FASEB Journal 27:9, pages 3487-3495.
Crossref
Suvi Kalliokoski, Ana-Marija Sulic, Ilma R. Korponay-Szabó, Zsuzsa Szondy, Rafael Frias, Mileidys Alea Perez, Stefania Martucciello, Anne Roivainen, Lauri J. Pelliniemi, Carla Esposito, Martin Griffin, Daniele Sblattero, Markku Mäki, Katri Kaukinen, Katri Lindfors & Sergio Caja. (2013) Celiac Disease–Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics. PLoS ONE 8:6, pages e65887.
Crossref
Rasmus Iversen, Roberto Di Niro, Jorunn Stamnaes, Knut E. A. Lundin, Patrick C. Wilson & Ludvig M. Sollid. (2013) Transglutaminase 2–Specific Autoantibodies in Celiac Disease Target Clustered, N-Terminal Epitopes Not Displayed on the Surface of Cells. The Journal of Immunology 190:12, pages 5981-5991.
Crossref
Siiri E. Iismaa, Mark Aplin, Sara Holman, Ting W. Yiu, Kristy Jackson, James G. Burchfield, Christopher J. Mitchell, Liam O’Reilly, Aimee Davenport, James Cantley, Carsten Schmitz-Peiffer, Trevor J. Biden, Gregory J. Cooney & Robert M. Graham. (2013) Glucose Homeostasis in Mice Is Transglutaminase 2 Independent. PLoS ONE 8:5, pages e63346.
Crossref
V. SCHROEDER & H.P. KOHLER. (2013) New developments in the area of factor XIII. Journal of Thrombosis and Haemostasis 11:2, pages 234-244.
Crossref
Kathleen Singer, Rong Luo, Sung-Jin Jeong & Xianhua Piao. (2012) GPR56 and the Developing Cerebral Cortex: Cells, Matrix, and Neuronal Migration. Molecular Neurobiology 47:1, pages 186-196.
Crossref
Lucia Russo, Claudia Marsella, Giovanni Nardo, Tania Massignan, Massimo Alessio, Emanuela Piermarini, Stefano La Rosa, Giovanna Finzi, Valentina Bonetto, Federico Bertuzzi, Pierre Maechler & Ornella Massa. (2012) Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E. Acta Diabetologica 50:1, pages 61-72.
Crossref
S. Beninati, F. Facchiano & M. Piacentini. (2012) Transglutaminases: future perspectives. Amino Acids 44:1, pages 1-9.
Crossref
Hyun Yoo, Eu-Ree Ahn, Se-Jin Kim, Seon-Hyeong Lee, Seung Hyun Oh & Soo-Youl Kim. (2012) Divergent results induced by different types of septic shock in transglutaminase 2 knockout mice. Amino Acids 44:1, pages 189-197.
Crossref
Stephanie Deasey, Shobana Shanmugasundaram & Maria Nurminskaya. (2011) Tissue-specific responses to loss of transglutaminase 2. Amino Acids 44:1, pages 179-187.
Crossref
Umberto Tarantino, Amedeo Ferlosio, Gaetano Arcuri, Luigi Giusto Spagnoli & Augusto Orlandi. (2011) Transglutaminase 2 as a biomarker of osteoarthritis: an update. Amino Acids 44:1, pages 199-207.
Crossref
Antonio Martin, Alessandro Giuliano, Domenico Collaro, Giulia De Vivo, Carla Sedia, Enrica Serretiello & Vittorio Gentile. (2011) Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases. Amino Acids 44:1, pages 111-118.
Crossref
Cornelius Klöck & Chaitan Khosla. (2012) Regulation of the activities of the mammalian transglutaminase family of enzymes. Protein Science 21:12, pages 1781-1791.
Crossref
Keunhee Oh, Hyung-Bae Park, Myung Won Seo, Ok-Jin Byoun & Dong-Sup Lee. (2012) Transglutaminase 2 exacerbates experimental autoimmune encephalomyelitis through positive regulation of encephalitogenic T cell differentiation and inflammation. Clinical Immunology 145:2, pages 122-132.
Crossref
Jin-Hee Kim, Eui Man Jeong, Young-Joo Jeong, Wang Jae Lee, Jae Seung Kang, In-Gyu Kim & Young-il Hwang. (2012) Transglutaminase 2 modulates antigen-specific antibody response by suppressing Blimp-1 and AID expression of B cells in mice. Immunology Letters 147:1-2, pages 18-28.
Crossref
Antonio Di Sabatino, Alessandro Vanoli, Paolo Giuffrida, Ombretta Luinetti, Enrico Solcia & Gino Roberto Corazza. (2012) The function of tissue transglutaminase in celiac disease. Autoimmunity Reviews 11:10, pages 746-753.
Crossref
M D'Eletto, M G Farrace, F Rossin, F Strappazzon, G Di Giacomo, F Cecconi, G Melino, S Sepe, S Moreno, G M Fimia, L Falasca, R Nardacci & M Piacentini. (2012) Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins. Cell Death & Differentiation 19:7, pages 1228-1238.
Crossref
Christopher S. McAllister & Martin F. Kagnoff. (2012) The immunopathogenesis of celiac disease reveals possible therapies beyond the gluten-free diet. Seminars in Immunopathology 34:4, pages 581-600.
Crossref
Cornelius Klöck, Thomas R. DiRaimondo & Chaitan Khosla. (2012) Role of transglutaminase 2 in celiac disease pathogenesis. Seminars in Immunopathology 34:4, pages 513-522.
Crossref
Laureline Berthelot, Christina Papista, Thiago T. Maciel, Martine Biarnes-Pelicot, Emilie Tissandie, Pamela H.M. Wang, Houda Tamouza, Agnès Jamin, Julie Bex-Coudrat, Aurelie Gestin, Ahmed Boumediene, Michelle Arcos-Fajardo, Patrick England, Evangéline Pillebout, Francine Walker, Eric Daugas, François Vrtosvnik, Martin Flamant, Marc Benhamou, Michel Cogné, Ivan C. Moura & Renato C. Monteiro. (2012) Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. Journal of Experimental Medicine 209:4, pages 793-806.
Crossref
Liquan Yang & Lei Xu. (2012) GPR56 in cancer progression: current status and future perspective. Future Oncology 8:4, pages 431-440.
Crossref
Kyle B. JohnsonHumphrey Petersen-JonesJanice M. ThompsonKiyotaka HitomiMiho ItohErik N. T. P. Bakker, Gail V. W. Johnson, Gozde Colak & Stephanie W. Watts. (2012) Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2. American Journal of Physiology-Heart and Circulatory Physiology 302:7, pages H1355-H1366.
Crossref
Hilary Grosso & M. Maral Mouradian. (2012) Transglutaminase 2: Biology, Relevance to Neurodegenerative Diseases and Therapeutic Implications. Pharmacology & Therapeutics 133:3, pages 392-410.
Crossref
Gozde Colak & Gail V.W. Johnson. (2012) Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia. Neurobiology of Disease 45:3, pages 1042-1050.
Crossref
Laila Dafik, Megan Albertelli, Jorunn Stamnaes, Ludvig M. Sollid & Chaitan Khosla. (2012) Activation and Inhibition of Transglutaminase 2 in Mice. PLoS ONE 7:2, pages e30642.
Crossref
Soner Gundemir, Gozde Colak, Janusz Tucholski & Gail V.W. Johnson. (2012) Transglutaminase 2: A molecular Swiss army knife. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:2, pages 406-419.
Crossref
Mireille DelhaseSoo-Youl Kim, Ho LeeAya Naiki-Ito, Yi ChenEu-Ree Ahn, Kazuhiro MurataSe-Jin Kim, Norman LautschKoichi S. Kobayashi, Tomoyuki Shirai, Michael KarinMakoto Nakanishi. (2011) TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2. Proceedings of the National Academy of Sciences 109:4.
Crossref
Maria V. Nurminskaya & Alexey M. Belkin. 2012. 1 97 .
Linda Ruggiero, Zsolt Sarang, Zsuzsa Szondy & Silvia C. Finnemann. 2012. Retinal Degenerative Diseases. Retinal Degenerative Diseases 731 737 .
Róbert Király, MátéÁ. Demény & László Fésüs. (2011) Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein. FEBS Journal 278:24, pages 4717-4739.
Crossref
Miriam E. Van Strien, Wia Baron, Erik N.T.P. Bakker, Jan Bauer, John G.J.M. Bol, John J.P. Brevé, Rob Binnekade, Willem J. Van Der Laarse, Benjamin Drukarch & Anne-Marie Van Dam. (2011) Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination. Glia 59:11, pages 1622-1634.
Crossref
Zsuzsa Szondy, Ilma Korponay‐Szabó, Róbert Király & László Fésüs. 2011. Advances in Enzymology. Advances in Enzymology 295 345 .
Mauro Piacentini, Manuela D'Eletto, Laura Falasca, Maria Grazia Farrace & Carlo Rodolfo. 2011. Advances in Enzymology. Advances in Enzymology 197 246 .
Guylaine Hoffner, Amandine Van Houtteghem, William André & Philippe Djian. 2011. Advances in Enzymology. Advances in Enzymology 97 160 .
Vittorio Gentile. 2011. Advances in Enzymology. Advances in Enzymology 47 95 .
Carlo M. Bergamini, Russell J. Collighan, Zhuo Wang & Martin Griffin. 2011. Advances in Enzymology. Advances in Enzymology 1 46 .
Xi Jin, Jorunn Stamnaes, Cornelius Klöck, Thomas R. DiRaimondo, Ludvig M. Sollid & Chaitan Khosla. (2011) Activation of Extracellular Transglutaminase 2 by Thioredoxin. Journal of Biological Chemistry 286:43, pages 37866-37873.
Crossref
Keunhee Oh, Hyung-Bae Park, Ok-Jin Byoun, Dong-Myung Shin, Eui Man Jeong, Young Whan Kim, Yon Su Kim, Gerry Melino, In-Gyu Kim & Dong-Sup Lee. (2011) Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice. Journal of Experimental Medicine 208:8, pages 1707-1719.
Crossref
Zsolt Sarang, Krisztina Köröskényi, Anna Pallai, Edina Duró, Gerry Melino, Martin Griffin, László Fésüs & Zsuzsa Szondy. (2011) Transglutaminase 2 null macrophages respond to lipopolysaccharide stimulation by elevated proinflammatory cytokine production due to an enhanced αvβ3 integrin-induced Src tyrosine kinase signaling. Immunology Letters 138:1, pages 71-78.
Crossref
L. M. Sollid & C. Khosla. (2011) Novel therapies for coeliac disease. Journal of Internal Medicine 269:6, pages 604-613.
Crossref
Yury Popov, Deanna Y. Sverdlov, Anisha K. Sharma, K. Ramakrishnan Bhaskar, Shaoyong Li, Tobias L. Freitag, James Lee, Walburga Dieterich, Gerry Melino & Detlef Schuppan. (2011) Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice. Gastroenterology 140:5, pages 1642-1652.
Crossref
Antonio Martin, Giulia De Vivo & Vittorio Gentile. (2011) Possible Role of the Transglutaminases in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases. International Journal of Alzheimer's Disease 2011, pages 1-8.
Crossref
Brandon Beagle & Gail V.W. Johnson. (2010) AES/GRG5: More than just a dominant-negative TLE/GRG family member. Developmental Dynamics 239:11, pages 2795-2805.
Crossref
Francesco Facchiano, Florence Deloye, Frédéric Doussau, Giulio Innamorati, Anthony C. Ashton, J. Oliver Dolly, Simone Beninati, Angelo Facchiano, Alberto Luini, Bernard Poulain & Fabio Benfenati. (2010) Transglutaminase participates in the blockade of neurotransmitter release by tetanus toxin: evidence for a novel biological function. Amino Acids 39:1, pages 257-269.
Crossref
Helen Williams, Richard J. Pease, Laura M. Newell, Paul A. Cordell, Robert M. Graham, Mark T. Kearney, Christopher L. Jackson & Peter J. Grant. (2010) Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse. Atherosclerosis 210:1, pages 94-99.
Crossref
Hideki Tatsukawa & Soichi Kojima. (2010) Recent advances in understanding the roles of transglutaminase 2 in alcoholic steatohepatitis. Cell Biology International 34:3, pages 325-334.
Crossref
Kohji KasaharaMasayoshi Souri, Mizuho KanedaToshiaki MikiNaomasa Yamamoto & Akitada Ichinose. (2010) Impaired clot retraction in factor XIII A subunit–deficient mice. Blood 115:6, pages 1277-1279.
Crossref
G -Y Jang, J -H Jeon, S -Y Cho, D -M Shin, C -W Kim, E M Jeong, H C Bae, T W Kim, S -H Lee, Y Choi, D -S Lee, S -C Park & I -G Kim. (2009) Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-κB activity in hypoxic tumor cells. Oncogene 29:3, pages 356-367.
Crossref
Mariangela Ricotta. (2010) Physio-pathological roles of transglutaminase-catalyzed reactions. World Journal of Biological Chemistry 1:5, pages 181.
Crossref
Sung-Yup ChoJin-Haeng LeeHan-Dong BaeEui Man JeongGi-Yong JangChai-Wan KimDong-Myung ShinJu-Hong JeonIn-Gyu Kim. (2010) Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax. Experimental and Molecular Medicine 42:9, pages 639.
Crossref
Marc Antonyak & Richard A. Cerione. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling 1795 1802 .
Lei Xu. 2010. Adhesion-GPCRs. Adhesion-GPCRs 98 108 .
Graham A. Heap & David A. van Heel. (2009) Genetics and pathogenesis of coeliac disease. Seminars in Immunology 21:6, pages 346-354.
Crossref
W Malorni, M G Farrace, P Matarrese, A Tinari, L Ciarlo, P Mousavi-Shafaei, M D'Eletto, G Di Giacomo, G Melino, L Palmieri, C Rodolfo & M Piacentini. (2009) The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis. Cell Death & Differentiation 16:11, pages 1480-1492.
Crossref
Beáta Tóth, Zsolt Sarang, György Vereb, Ailiang Zhang, Sakae Tanaka, Gerry Melino, László Fésüs & Zsuzsa Szondy. (2009) Over-expression of integrin β3 can partially overcome the defect of integrin β3 signaling in transglutaminase 2 null macrophages. Immunology Letters 126:1-2, pages 22-28.
Crossref
Siiri E. Iismaa, Bryony M. Mearns, Laszlo Lorand & Robert M. Graham. (2009) Transglutaminases and Disease: Lessons From Genetically Engineered Mouse Models and Inherited Disorders. Physiological Reviews 89:3, pages 991-1023.
Crossref
Alessandra Scarpellini, Renée Germack, Hugues Lortat-Jacob, Takashi Muramatsu, Ellen Billett, Timothy Johnson & Elisabetta A.M. Verderio. (2009) Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2. Journal of Biological Chemistry 284:27, pages 18411-18423.
Crossref
Mileidys Perez Alea, Miyako Kitamura, Guillaume Martin, Vincent Thomas, Kiyotaka Hitomi & Saïd El Alaoui. (2009) Development of an isoenzyme-specific colorimetric assay for tissue transglutaminase 2 cross-linking activity. Analytical Biochemistry 389:2, pages 150-156.
Crossref
Hideki Tatsukawa, Yayoi Fukaya, Gordon Frampton, Antonio Martinez–Fuentes, Kenji Suzuki, Ting–Fang Kuo, Keisuke Nagatsuma, Kentaro Shimokado, Masataka Okuno, Jian Wu, Siiri Iismaa, Tomokazu Matsuura, Hidekazu Tsukamoto, Mark A. Zern, Robert M. Graham & Soichi Kojima. (2009) Role of Transglutaminase 2 in Liver Injury via Cross-linking and Silencing of Transcription Factor Sp1. Gastroenterology 136:5, pages 1783-1795.e10.
Crossref
Daniela Tavian, Roberto Colombo, Francesco Misiti, Pasquale Ena, Luca Ena, Beatrice Sampaolese, Bruno Giardina & Maria E. Clementi. (2009) Fibroblast apoptosis in a patient affected by lamellar ichthyosis. Journal of Cutaneous Pathology 36:4, pages 417-424.
Crossref
Simone Beninati, Carlo M. Bergamini & Mauro Piacentini. (2008) An overview of the first 50 years of transglutaminase research. Amino Acids 36:4, pages 591-598.
Crossref
U. Tarantino, F. Oliva, G. Taurisano, A. Orlandi, V. Pietroni, E. Candi, G. Melino & N. Maffulli. (2008) FXIIIA and TGF-β over-expression produces normal musculo-skeletal phenotype in TG2-/- mice. Amino Acids 36:4, pages 679-684.
Crossref
Z. Sarang, B. Tóth, Z. Balajthy, K. Köröskényi, É. Garabuczi, L. Fésüs & Z. Szondy. (2008) Some lessons from the tissue transglutaminase knockout mouse. Amino Acids 36:4, pages 625-631.
Crossref
A. Orlandi, F. Oliva, G. Taurisano, E. Candi, A. Di Lascio, G. Melino, L. G. Spagnoli & U. Tarantino. (2008) Transglutaminase-2 differently regulates cartilage destruction and osteophyte formation in a surgical model of osteoarthritis. Amino Acids 36:4, pages 755-763.
Crossref
K. Mehta. (2008) Biological and therapeutic significance of tissue transglutaminase in pancreatic cancer. Amino Acids 36:4, pages 709-716.
Crossref
G. Di Giacomo, A. Lentini, S. Beninati, M. Piacentini & C. Rodolfo. (2008) In vivo evaluation of type 2 transglutaminase contribution to the metastasis formation in melanoma. Amino Acids 36:4, pages 717-724.
Crossref
Eui Man Jeong, Chai-Wan Kim, Sung-Yup Cho, Gi-Yong Jang, Dong-Myung Shin, Ju-Hong Jeon & In-Gyu Kim. (2009) Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stress. FEBS Letters 583:4, pages 648-654.
Crossref
Beáta Tóth, Éva Garabuczi, Zsolt Sarang, György Vereb, György Vámosi, Daniel Aeschlimann, Bernadett Blaskó, Bálint Bécsi, Ferenc Erdõdi, Adam Lacy-Hulbert, Ailiang Zhang, Laura Falasca, Raymond B. Birge, Zoltán Balajthy, Gerry Melino, László Fésüs & Zsuzsa Szondy. (2009) Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells. The Journal of Immunology 182:4, pages 2084-2092.
Crossref
Marie Fisher, Richard A. Jones, Linghong Huang, John L. Haylor, Meguid El Nahas, Martin Griffin & Timothy S. Johnson. (2009) Modulation of tissue transglutaminase in tubular epithelial cells alters extracellular matrix levels: A potential mechanism of tissue scarring. Matrix Biology 28:1, pages 20-31.
Crossref
Kapil Mehta & Jansina Y. Fok. 2009. Drug Resistance in Cancer Cells. Drug Resistance in Cancer Cells 95 114 .
Nasim Shweke, Nada Boulos, Chantal Jouanneau, Sophie Vandermeersch, Gerry Melino, Jean-Claude Dussaule, Christos Chatziantoniou, Pierre Ronco & Jean-Jacques Boffa. (2008) Tissue Transglutaminase Contributes to Interstitial Renal Fibrosis by Favoring Accumulation of Fibrillar Collagen through TGF-β Activation and Cell Infiltration. The American Journal of Pathology 173:3, pages 631-642.
Crossref
Dong-Myung Shin, Ju-Hong Jeon, Chai-Wan Kim, Sung-Yup Cho, Hye-Jin Lee, Gi-Yong Jang, Eui Man Jeong, Dong-Sup Lee, Ja-Heon Kang, Gerry Melino, Sang-Chul Park & In-Gyu Kim. (2008) TGFβ mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation. The FASEB Journal 22:7, pages 2498-2507.
Crossref
Matthew Siegel, Pavel Strnad, R. Edward Watts, Kihang Choi, Bana Jabri, M. Bishr Omary & Chaitan Khosla. (2008) Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury. PLoS ONE 3:3, pages e1861.
Crossref
Pål Stenberg, E. Bodil Roth & Klas Sjöberg. (2008) Transglutaminase and the pathogenesis of coeliac disease. European Journal of Internal Medicine 19:2, pages 83-91.
Crossref
Laura Falasca, Maria Grazia Farrace, Alessandra Rinaldi, Loretta Tuosto, Gennard Melino & Mauro Piacentini. (2008) Transglutaminase Type II Is Involved in the Pathogenesis of Endotoxic Shock. The Journal of Immunology 180:4, pages 2616-2624.
Crossref
Sandor Boros, Phillip A. Wilmarth, Bram Kamps, Wilfried W. de Jong, Hans Bloemendal, Kirsten Lampi & Wilbert C. Boelens. (2008) Tissue transglutaminase catalyzes the deamidation of glutamines in lens βB2- and βB3-crystallins. Experimental Eye Research 86:2, pages 383-393.
Crossref
Carlo Rodolfo, Laura Falasca, Giuseppina Di Giacomo, Pier Giorgio Mastroberardino & Mauro Piacentini. 2008. Programmed Cell Death,General Principles forStudying Cell Death, Part A. Programmed Cell Death,General Principles forStudying Cell Death, Part A 201 212 .
Z Sarang, A Mádi, C Koy, S Varga, M O Glocker, D S Ucker, S Kuchay, A H Chishti, G Melino, L Fésüs & Z Szondy. (2007) Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes. Cell Death & Differentiation 14:10, pages 1842-1844.
Crossref
Amit Verma & Kapil Mehta. (2007) Tissue transglutaminase-mediated chemoresistance in cancer cells. Drug Resistance Updates 10:4-5, pages 144-151.
Crossref
P. Kotsakis & M. Griffin. (2007) Tissue transglutaminase in tumour progression: friend or foe?. Amino Acids 33:2, pages 373-384.
Crossref
Yukiko Nakano, Hadil F. Al-Jallad, Aisha Mousa & Mari T. Kaartinen. (2007) Expression and Localization of Plasma Transglutaminase Factor XIIIA in Bone. Journal of Histochemistry & Cytochemistry 55:7, pages 675-685.
Crossref
Gail A. Cornwall, H. Henning von Horsten, Douglas Swartz, Seethal Johnson, Kim Chau & Sandra Whelly. (2007) Extracellular quality control in the epididymis. Asian Journal of Andrology 9:4, pages 500-507.
Crossref
Suresh Mishra, Gerry Melino & Liam J. Murphy. (2007) Transglutaminase 2 Kinase Activity Facilitates Protein Kinase A-induced Phosphorylation of Retinoblastoma Protein. Journal of Biological Chemistry 282:25, pages 18108-18115.
Crossref
L Yuan, M Siegel, K Choi, C Khosla, C R Miller, E N Jackson, D Piwnica-Worms & K M Rich. (2006) Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy. Oncogene 26:18, pages 2563-2573.
Crossref
Christophe Guilluy, Malvyne Rolli-Derkinderen, Pierre-Louis Tharaux, Gerry Melino, Pierre Pacaud & Gervaise Loirand. (2007) Transglutaminase-dependent RhoA Activation and Depletion by Serotonin in Vascular Smooth Muscle Cells. Journal of Biological Chemistry 282:5, pages 2918-2928.
Crossref
Giuseppe Battaglia, Maria Grazia Farrace, Pier Giorgio Mastroberardino, Irene Viti, Gian Maria Fimia, Jozef Van Beeumen, Bart Devreese, Gennaro Melino, Gemma Molinaro, Carla Letizia Busceti, Francesca Biagioni, Ferdinando Nicoletti & Mauro Piacentini. (2007) Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders. Journal of Neurochemistry 100:1, pages 36-49.
Crossref
A. J. L. Cooper & S.-Y. Kim. 2007. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 243 258 .
Zoltán BalajthyKrisztián CsomósGyörgy VámosiAttila SzántóMichel LanotteLászló Fésüs. (2006) Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions. Blood 108:6, pages 2045-2054.
Crossref
R A Jones, P Kotsakis, T S Johnson, D Y S Chau, S Ali, G Melino & M Griffin. (2005) Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth. Cell Death & Differentiation 13:9, pages 1442-1453.
Crossref
Pier Giorgio Mastroberardino, Maria Grazia Farrace, Irene Viti, Flaminia Pavone, Gian Maria Fimia, Gennaro Melino, Carlo Rodolfo & Mauro Piacentini. (2006) “Tissue” transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1757:9-10, pages 1357-1365.
Crossref
Erik N.T.P. BakkerAdrian PisteaJos A.E. SpaanTitia RolfCarlie J. de VriesNico van RooijenEleonara CandiEd VanBavel. (2006) Flow-Dependent Remodeling of Small Arteries in Mice Deficient for Tissue-Type Transglutaminase. Circulation Research 99:1, pages 86-92.
Crossref
J F Herman, L S Mangala & K Mehta. (2006) Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells. Oncogene 25:21, pages 3049-3058.
Crossref
Janusz Tucholski, Kevin A. Roth & Gail V. W. Johnson. (2006) Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage. Journal of Neurochemistry 97:2, pages 582-594.
Crossref
Hadil F. Al-Jallad, Yukiko Nakano, Jeff L.Y. Chen, Erin McMillan, Céline Lefebvre & Mari T. Kaartinen. (2006) Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures. Matrix Biology 25:3, pages 135-148.
Crossref
J.J. Wakshlag, C.J. McNeill, M.A. Antonyak, J.E. Boehm, R. Fuji, C.E. Balkman, M. Zgola, R.A. Cerione & R.L. Page. (2006) Expression and Activity of Transglutaminase II in Spontaneous Tumours of Dogs and Cats. Journal of Comparative Pathology 134:2-3, pages 202-210.
Crossref
Shawn M. JobeLorie LeoJoshua S. EastvoldGerhard DickneiteTimothy L. RatliffSteven R. LentzJorge Di Paola. (2005) Role of FcRγ and factor XIIIA in coated platelet formation. Blood 106:13, pages 4146-4151.
Crossref
S Lippens, G Denecker, P Ovaere, P Vandenabeele & W Declercq. (2005) Death penalty for keratinocytes: apoptosis versus cornification. Cell Death & Differentiation 12:S2, pages 1497-1508.
Crossref
I. R. KORPONAY-SZABO, T. RAIVIO, K. LAURILA, J. OPRE, R. KIRALY, J. B. KOVACS, K. KAUKINEN, L. FESUS & M. MAKI. (2005) Coeliac disease case finding and diet monitoring by point-of-care testing. Alimentary Pharmacology and Therapeutics 22:8, pages 729-737.
Crossref
Suk Keun Lee, Yeon Sook Kim, Sang Shin Lee, Young Joon Lee, In Sun Song, Sang Chul Park, Je Geun Chi & Soo Il Chung. (2005) Antisense inhibition of transglutaminase 2 affects development of mouse embryo submandibular gland in organ culture. Archives of Oral Biology 50:9, pages 789-798.
Crossref
Zsolt Sarang, Péter Molnár, Tamás Németh, Szabolcs Gomba, Tamás Kardon, Gerry Melino, Susanna Cotecchia, László Fésüs & Zsuzsa Szondy. (2005) Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice. Hepatology 42:3, pages 578-587.
Crossref
Azin Agah, Themis R. Kyriakides & Paul Bornstein. (2005) Proteolysis of Cell-Surface Tissue Transglutaminase by Matrix Metalloproteinase-2 Contributes to the Adhesive Defect and Matrix Abnormalities in Thrombospondin-2-Null Fibroblasts and Mice. The American Journal of Pathology 167:1, pages 81-88.
Crossref
László Fésüs & Zsuzsa Szondy. (2005) Transglutaminase 2 in the balance of cell death and survival. FEBS Letters 579:15, pages 3297-3302.
Crossref

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