Citations (40)
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Read on this site (5)
Adnan M. Al-Ayoubi, Hui Zheng, Yuying Liu, Tao Bai & Scott T. Eblen. (2012) Mitogen-Activated Protein Kinase Phosphorylation of Splicing Factor 45 (SPF45) Regulates SPF45 Alternative Splicing Site Utilization, Proliferation, and Cell Adhesion. Molecular and Cellular Biology 32:14, pages 2880-2893.
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Linda S Steelman, Kristin M Stadelman, William H Chappell, Stefan Horn, Jörg Bäsecke, Melchiorre Cervello, Ferdinando Nicoletti, Massimo Libra, Franca Stivala, Alberto M Martelli & James A McCubrey. (2008) Akt as a therapeutic target in cancer. Expert Opinion on Therapeutic Targets 12:9, pages 1139-1165.
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Seunghee Yoon & Rony Seger. (2006) The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions. Growth Factors 24:1, pages 21-44.
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Scott T. Eblen, Jill K. Slack-Davis, Adel Tarcsafalvi, J. Thomas Parsons, Michael J. Weber & Andrew D. Catling. (2004) Mitogen-Activated Protein Kinase Feedback Phosphorylation Regulates MEK1 Complex Formation and Activation during Cellular Adhesion. Molecular and Cellular Biology 24:6, pages 2308-2317.
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Scott T. Eblen, Jill K. Slack, Michael J. Weber & Andrew D. Catling. (2002) Rac-PAK Signaling Stimulates Extracellular Signal-Regulated Kinase (ERK) Activation by Regulating Formation of MEK1-ERK Complexes. Molecular and Cellular Biology 22:17, pages 6023-6033.
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Articles from other publishers (35)
Renee Barbosa, Lucila A. Acevedo & Ronen Marmorstein. (2021) The MEK/ERK Network as a Therapeutic Target in Human Cancer. Molecular Cancer Research 19:3, pages 361-374.
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Amber Bradley, Hui Zheng, Angela Ziebarth, Wayne Sakati, Melissa Branham-O’Connor, Joe B. Blumer, Yuying Liu, Emily Kistner-Griffin, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Anil K. Sood, Charles N. LandenJrJr & Scott T. Eblen. (2014) EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer. Carcinogenesis 35:5, pages 1100-1109.
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Yuying Liu, LaShardai Conaway, Jennifer Rutherford Bethard, Adnan M. Al-Ayoubi, Amber Thompson Bradley, Hui Zheng, Scott A. Weed & Scott T. Eblen. (2013) Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion. Nucleic Acids Research 41:9, pages 4949-4962.
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Sunbae Lee & Yun Soo Bae. (2012) Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis. Molecules and Cells 33:4, pages 325-334.
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Alessia E. Russo, Ylenia Bevelacqua, Andrea Marconi, Andrea Veronesi & Massimo Libra. 2012. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma
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Matilde Marchi, Laura Pancrazi, Margherita Maffei, G. Michele Ratto & Mario Costa. (2010) ERK1 nucleocytoplasmic shuttling rate depends on specific N-terminal aminoacids. Biochemical and Biophysical Research Communications 398:2, pages 166-172.
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James A. McCubrey, Stephen L. Abrams, Kristin Stadelman, William H. Chappell, Michelle LaHair, Richard A. Ferland & Linda S. Steelman. (2010) Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells. Advances in Enzyme Regulation 50:1, pages 285-307.
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Hui Zheng, Adnan Al-Ayoubi & Scott T. Eblen. 2010. MAP Kinase Signaling Protocols. MAP Kinase Signaling Protocols
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Zhong Yao & Rony Seger. (2009) The ERK signaling cascade-Views from different subcellular compartments. BioFactors 35:5, pages 407-416.
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Adnan Al-Ayoubi, Adel Tarcsafalvi, Hui Zheng, Wayne Sakati & Scott T. Eblen. (2008) ERK activation and nuclear signaling induced by the loss of cell/matrix adhesion stimulates anchorage-independent growth of ovarian cancer cells. Journal of Cellular Biochemistry 105:3, pages 875-884.
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L S Steelman, S L Abrams, J Whelan, F E Bertrand, D E Ludwig, J Bäsecke, M Libra, F Stivala, M Milella, A Tafuri, P Lunghi, A Bonati, A M Martelli & J A McCubrey. (2008) Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 22:4, pages 686-707.
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Asami Kaihara & Yoshio Umezawa. (2008) Genetically Encoded Bioluminescent Indicator for ERK2 Dimer in Living Cells. Chemistry – An Asian Journal 3:1, pages 38-45.
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James A. McCubrey, Melissa L. Sokolosky, Brian D. Lehmann, Jackson R. Taylor, Patrick M. Navolanic, William H. Chappell, Stephen L. Abrams, Kristin M. Stadelman, Ellis W.T. Wong, Negin Misaghian, Stefan Horn, Jörg Bäsecke, Massimo Libra, Franca Stivala, Giovanni Ligresti, Agostino Tafuri, Michele Milella, Marek Zarzycki, Andrzej Dzugaj, Francesca Chiarini, Camilla Evangelisti, Alberto M. Martelli, David M. Terrian, Richard A. Franklin & Linda S. Steelman. (2008) Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy. Advances in Enzyme Regulation 48:1, pages 113-135.
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James A. McCubrey, Richard A. Franklin, Fred E. Bertrand, Jackson R. Taylor, William H. Chappell, Melissa L. Midgett, Ellis W. T. Wong, Stephen L. Abrams, Kristin M. Stadelman, Negin Misaghian, Dale L. Ludwig, Jorg Basecke, Massimo Libra, Franca Stivala, Michele Milella, Agostino Tafuri, Alberto M. Martelli, Paolo Lungi, Antonio Bonati, David M. Terrian, Brian D. Lehmann & Linda S. Steelman. 2008. Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy. Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy
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Sarit Bendetz-Nezer & Rony Seger. (2007) Role of Non-phosphorylated Activation Loop Residues in Determining ERK2 Dephosphorylation, Activity, and Subcellular Localization. Journal of Biological Chemistry 282:34, pages 25114-25122.
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Yoav D. Shaul & Rony Seger. (2007) The MEK/ERK cascade: From signaling specificity to diverse functions. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:8, pages 1213-1226.
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Nam Y. Lee & Gerard C. Blobe. (2007) The Interaction of Endoglin with β-Arrestin2 Regulates Transforming Growth Factor-β-mediated ERK Activation and Migration in Endothelial Cells. Journal of Biological Chemistry 282:29, pages 21507-21517.
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Malka Cohen-Armon, Leonid Visochek, Dana Rozensal, Adi Kalal, Ilona Geistrikh, Rodika Klein, Sarit Bendetz-Nezer, Zhong Yao & Rony Seger. (2007) DNA-Independent PARP-1 Activation by Phosphorylated ERK2 Increases Elk1 Activity: A Link to Histone Acetylation. Molecular Cell 25:2, pages 297-308.
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James A. McCubrey, Linda S. Steelman, Richard A. Franklin, Steven L. Abrams, William H. Chappell, Ellis W.T. Wong, Brian D. Lehmann, David M. Terrian, Jorg Basecke, Franca Stivala, Massimo Libra, Camilla Evangelisti & Alberto M. Martelli. (2007) Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance. Advances in Enzyme Regulation 47:1, pages 64-103.
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Eran Perlson, Izhak Michaelevski, Noga Kowalsman, Keren Ben-Yaakov, Maya Shaked, Rony Seger, Miriam Eisenstein & Mike Fainzilber. (2006) Vimentin Binding to Phosphorylated Erk Sterically Hinders Enzymatic Dephosphorylation of the Kinase. Journal of Molecular Biology 364:5, pages 938-944.
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Daniel Gioeli, Ben E. Black, Vicki Gordon, Adam Spencer, Cristina T. Kesler, Scott T. Eblen, Bryce M. Paschal & Michael J. Weber. (2006) Stress Kinase Signaling Regulates Androgen Receptor Phosphorylation, Transcription, and Localization. Molecular Endocrinology 20:3, pages 503-515.
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Tetsuya Mizutani, Shuetsu Fukushi, Masayuki Saijo, Ichiro Kurane & Shigeru Morikawa. (2006) Regulation of p90RSK phosphorylation by SARS-CoV infection in Vero E6 cells. FEBS Letters 580:5, pages 1417-1424.
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S. Grewal, D.M. Molina & L. Bardwell. (2006) Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo. Cellular Signalling 18:1, pages 123-134.
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Thomas Prince & Robert L. Matts. (2005) Exposure of protein kinase motifs that trigger binding of Hsp90 and Cdc37. Biochemical and Biophysical Research Communications 338:3, pages 1447-1454.
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Kari Callaway, Mark A. Rainey & Kevin N. Dalby. (2005) Quantifying ERK2–protein interactions by fluorescence anisotropy: PEA-15 inhibits ERK2 by blocking the binding of DEJL domains. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1754:1-2, pages 316-323.
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Céline Tárrega, Pablo Ríos, Rocío Cejudo-Marín, Carmen Blanco-Aparicio, Lieke van den Berk, Jan Schepens, Wiljan Hendriks, Lydia Tabernero & Rafael Pulido. (2005) ERK2 Shows a Restrictive and Locally Selective Mechanism of Recognition by Its Tyrosine Phosphatase Inactivators Not Shared by Its Activator MEK1. Journal of Biological Chemistry 280:45, pages 37885-37894.
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Ada Viterbo, Michal Harel, Benjamin A. Horwitz, Ilan Chet & Prasun K. Mukherjee. (2005) Trichoderma Mitogen-Activated Protein Kinase Signaling Is Involved in Induction of Plant Systemic Resistance. Applied and Environmental Microbiology 71:10, pages 6241-6246.
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N.Vinay Kumar, Scott T. Eblen & Michael J. Weber. (2004) Identifying specific kinase substrates through engineered kinases and ATP analogs. Methods 32:4, pages 389-397.
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Scott T. Eblen, N. Vinay Kumar, Kavita Shah, Michelle J. Henderson, Colin K.W. Watts, Kevan M. Shokat & Michael J. Weber. (2003) Identification of Novel ERK2 Substrates through Use of an Engineered Kinase and ATP Analogs. Journal of Biological Chemistry 278:17, pages 14926-14935.
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Fred L. Robinson, Angelique W. Whitehurst, Malavika Raman & Melanie H. Cobb. (2002) Identification of Novel Point Mutations in ERK2 That Selectively Disrupt Binding to MEK1. Journal of Biological Chemistry 277:17, pages 14844-14852.
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Megan J. Robinson, Bing-e Xu, Stephen Stippec & Melanie H. Cobb. (2002) Different Domains of the Mitogen-activated Protein Kinases ERK3 and ERK2 Direct Subcellular Localization and Upstream Specificityin Vivo. Journal of Biological Chemistry 277:7, pages 5094-5100.
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Céline Tárrega, Carmen Blanco-Aparicio, Juan José Muñoz & Rafael Pulido. (2002) Two Clusters of Residues at the Docking Groove of Mitogen-activated Protein Kinases Differentially Mediate Their Functional Interaction with the Tyrosine Phosphatases PTP-SL and STEP. Journal of Biological Chemistry 277:4, pages 2629-2636.
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Yong-Jie Zhou, Min Chen, Nancy A. Cusack, Lida H. Kimmel, Kelly S. Magnuson, James G. Boyd, Wen Lin, Joseph L. Roberts, Andrea Lengi, Rebecca H. Buckley, Robert L. Geahlen, Fabio Candotti, Massimo Gadina, Paul S. Changelian & John J. O'Shea. (2001) Unexpected Effects of FERM Domain Mutations on Catalytic Activity of Jak3. Molecular Cell 8:5, pages 959-969.
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Bing-e Xu, Steve Stippec, Fred L. Robinson & Melanie H. Cobb. (2001) Hydrophobic as Well as Charged Residues in Both MEK1 and ERK2 Are Important for Their Proper Docking. Journal of Biological Chemistry 276:28, pages 26509-26515.
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Ido Wolf, Hadara Rubinfeld, Seunghee Yoon, Goldie Marmor, Tamar Hanoch & Rony Seger. (2001) Involvement of the Activation Loop of ERK in the Detachment from Cytosolic Anchoring. Journal of Biological Chemistry 276:27, pages 24490-24497.
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