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Transcriptional Regulation

Embryonic but Not Postnatal Reexpression of Hepatocyte Nuclear Factor 1α (HNF1α) Can Reactivate the Silent Phenylalanine Hydroxylase Gene in HNF1α-Deficient Hepatocytes

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Pages 3662-3670 | Received 02 Feb 2001, Accepted 08 Mar 2001, Published online: 27 Mar 2023

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P. Firdous, K. Nissar, S. R. Masoodi, J. A. Wani, T. Hassan & B. A. Ganai. (2022) HNF1α upregulation and promoter hypermethylation as a cause of glucose dysregulation: a case–control study of Kashmiri MODY population. Journal of Endocrinological Investigation 46:5, pages 915-926.
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Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang & Yiqun Deng. (2015) Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1 α , and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46 . Drug Metabolism and Disposition 43:10, pages 1458-1467.
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Steven T. Okino, Deepa Pookot, Shahana Majid, Hong Zhao, Long-Cheng Li, Robert F. Place & Rajvir Dahiya. (2007) Chromatin changes on theGSTP1 promoter associated with its inactivation in prostate cancer. Molecular Carcinogenesis 46:10, pages 839-846.
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Tjalling Bosse, John J. Fialkovich, Christina M. Piaseckyj, Eva Beuling, Henrike Broekman, Richard J. Grand, Robert K. Montgomery & Stephen D. Krasinski. (2007) Gata4 and Hnf1α are partially required for the expression of specific intestinal genes during development . American Journal of Physiology-Gastrointestinal and Liver Physiology 292:5, pages G1302-G1314.
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Reini F. Luco, Miguel A. Maestro, Natalia del Pozo, William M. Philbrick, Pablo Perez de la Ossa & Jorge Ferrer. (2006) A Conditional Model Reveals That Induction of Hepatocyte Nuclear Factor-1α in Hnf1α -Null Mutant β-Cells Can Activate Silenced Genes Postnatally, Whereas Overexpression Is Deleterious . Diabetes 55:8, pages 2202-2211.
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Tjalling Bosse, Herbert M. van Wering, Marieke Gielen, Lauren N. Dowling, John J. Fialkovich, Christina M. Piaseckyj, Frank J. Gonzalez, Taro E. Akiyama, Robert K. Montgomery, Richard J. Grand & Stephen D. Krasinski. (2006) Hepatocyte nuclear factor-1α is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. American Journal of Physiology-Gastrointestinal and Liver Physiology 290:5, pages G1016-G1024.
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Hanoch Cassuto, Yael Olswang, Shmuel Heinemann, Karen Sabbagh, Richard W. Hanson & Lea Reshef. (2003) The transcriptional regulation of phosphoenolpyruvate carboxykinase gene in the kidney requires the HNF-1 binding site of the gene. Gene 318, pages 177-184.
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A Watt. (2003) HNF4: A central regulator of hepatocyte differentiation and function. Hepatology 37:6, pages 1249-1253.
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Young Hye Kwon, Aleksandra Jovanovic, Michael S. Serfas, Hiroaki Kiyokawa & Angela L. Tyner. (2002) p21 Functions to Maintain Quiescence of p27-deficient Hepatocytes. Journal of Biological Chemistry 277:44, pages 41417-41422.
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Claire Cheret, Antonia Doyen, Moshe Yaniv & Marco Pontoglio. (2002) Hepatocyte Nuclear Factor 1 α Controls Renal Expression of the Npt1-Npt4 Anionic Transporter Locus. Journal of Molecular Biology 322:5, pages 929-941.
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Marco Pontoglio, Mario Pausa, Antonia Doyen, Benoit Viollet, Moshe Yaniv & Francesco Tedesco. (2001) Hepatocyte Nuclear Factor 1α Controls the Expression of Terminal Complement Genes. Journal of Experimental Medicine 194:11, pages 1683-1690.
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