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Colleen C. Caldwell & Maria Spies. (2020) Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair. Critical Reviews in Biochemistry and Molecular Biology 55:5, pages 482-507.
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Cun-Shuan Xu, Heng-Yi Shao, Shuai-Shuai Liu, Bo Qin, Xiu-Feng Sun & Lin Tian. (2009) Possible regulation of genes associated with intracellular signaling cascade in rat liver regeneration. Scandinavian Journal of Gastroenterology 44:4, pages 462-470.
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Kristina Herzberg, Vladimir I. Bashkirov, Michael Rolfsmeier, Edwin Haghnazari, W. Hayes McDonald, Scott Anderson, Elena V. Bashkirova, John R. Yates$suffix/text()$suffix/text() & Wolf-Dietrich Heyer. (2006) Phosphorylation of Rad55 on Serines 2, 8, and 14 Is Required for Efficient Homologous Recombination in the Recovery of Stalled Replication Forks. Molecular and Cellular Biology 26:22, pages 8396-8409.
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Göran O. Bylund & Peter M. J. Burgers. (2005) Replication Protein A-Directed Unloading of PCNA by the Ctf18 Cohesion Establishment Complex. Molecular and Cellular Biology 25:13, pages 5445-5455.
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Lisa A. Anderson & Neil D. Perkins. (2003) Regulation of RelA (p65) Function by the Large Subunit of Replication Factor C. Molecular and Cellular Biology 23:2, pages 721-732.
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Articles from other publishers (76)
Carlos E. Sanz-Rodríguez, Benjamin Hoffman, Paul J. Guyett, Andrei Purmal, Baljinder Singh, Michael P. Pollastri & Kojo Mensa-Wilmot. (2022) Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug Development. Molecular Pharmacology 102:1, pages 1-16.
Crossref
Crossref
Christl Gaubitz, Xingchen Liu, Joshua Pajak, Nicholas P Stone, Janelle A Hayes, Gabriel Demo & Brian A Kelch. (2022) Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. eLife 11.
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Jiangchuan Shen, Yiling Zhao, Nhung Tuyet Pham, Yuxi Li, Yixiang Zhang, Jonathan Trinidad, Grzegorz Ira, Zhi Qi & Hengyao Niu. (2022) Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble. Nature Communications 13:1.
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Crossref
Ping ChenYayue LiuXiaochen MaQingli LiYangfan ZhangQingqing XiongTianqiang Song. (2021) Replication Factor C4 in human hepatocellular carcinoma: A potent prognostic factor associated with cell proliferation. BioScience Trends 15:4, pages 249-256.
Crossref
Crossref
Nan Wang, Yuanting Gu, Jiangrui Chi, Xinwei Liu, Youyi Xiong, Chaochao Zhong, Fang Wang, Xinxing Wang & Lin Li. (2021) Screening of DNA Damage Repair Genes Involved in the Prognosis of Triple-Negative Breast Cancer Patients Based on Bioinformatics. Frontiers in Genetics 12.
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Crossref
Kuo-Hao Ho, Tai-Chih Kuo, Yi-Ting Lee, Peng-Hsu Chen, Chwen-Ming Shih, Chia-Hsiung Cheng, Ann-Jeng Liu, Chin-Cheng Lee & Ku-Chung Chen. (2020) Xanthohumol regulates miR-4749-5p-inhibited RFC2 signaling in enhancing temozolomide cytotoxicity to glioblastoma. Life Sciences 254, pages 117807.
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Crossref
Min Zhang, Wenhai Li, Jun Feng, Zaixin Gong, Yang Yao & Caixia Zheng. (2020) Integrative transcriptomics and proteomics analysis constructs a new molecular model for ovule abortion in the female-sterile line of Pinus tabuliformis Carr.. Plant Science 294, pages 110462.
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Crossref
Taewoo Ryu, Heather D. Veilleux, Philip L. Munday, Imgook Jung, Jennifer M. Donelson & Timothy Ravasi. (2020) An Epigenetic Signature for Within-Generational Plasticity of a Reef Fish to Ocean Warming. Frontiers in Marine Science 7.
Crossref
Crossref
Weiping Chen, Song Zhu, Yifei Zhang, Jinghua Xiao & Dongbo Tian. (2019) Identification of key candidate tumor biomarkers in non‑small‑cell lung cancer by in silico analysis. Oncology Letters.
Crossref
Crossref
Wan-Xia Yang, Yun-Yan Pan & Chong-Ge You. (2019) CDK1, CCNB1, CDC20, BUB1, MAD2L1, MCM3, BUB1B, MCM2, and RFC4 May Be Potential Therapeutic Targets for Hepatocellular Carcinoma Using Integrated Bioinformatic Analysis. BioMed Research International 2019, pages 1-16.
Crossref
Crossref
Xue-Cen Wang, Xin Yue, Rong-Xin Zhang, Ting-Yu Liu, Zhi-Zhong Pan, Meng-Jie Yang, Zhen-Hai Lu, Zi-Yang Wang, Jian-Hong Peng, Li-Yuan Le, Gao-Yuan Wang, Qi-Hua Peng, Yuan Meng, Wenlin Huang & Ran-Yi Liu. (2019) Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair. Clinical Cancer Research 25:14, pages 4567-4579.
Crossref
Crossref
Tiffany C. Armenta, Steve W. Cole, Robert K. Wayne & Daniel T. Blumstein. (2019) Adaptive gene regulation in wild mammals exposed to high predator abundance. Animal Behaviour 152, pages 53-61.
Crossref
Crossref
Meng Wang, Tian Xie, Yingjie Wu, Qian Yin, Songping Xie, Qingyu Yao, Jie Xiong & Qiuping Zhang. (2018) Identification of RFC5 as a novel potential prognostic biomarker in lung cancer through bioinformatics analysis. Oncology Letters.
Crossref
Crossref
Yueyue Chen, Jie Qian, Li You, Xiufeng Zhang, Jinxia Jiao, Yang Liu & Jie Zhao. (2018) Subunit Interaction Differences Between the Replication Factor C Complexes in Arabidopsis and Rice. Frontiers in Plant Science 9.
Crossref
Crossref
Jie Qian, Yueyue Chen, Ying Hu, Yingtian Deng, Yang Liu, Gang Li, Wenxuan Zou & Jie Zhao. (2018)
Arabidopsis
replication factor C4 is critical for DNA replication during the mitotic cell cycle
. The Plant Journal 94:2, pages 288-303.
Crossref
Crossref
Peter A van Dam, Christian Rolfo, Rossana Ruiz, Patrick Pauwels, Christophe Van Berckelaer, XuanBich Trinh, Jose Ferri Gandia, Johannes P. Bogers & Steven Van Laere. (2018) Potential new biomarkers for squamous carcinoma of the uterine cervix. ESMO Open 3:4, pages e000352.
Crossref
Crossref
Divya Iyer & Nicholas Rhind. (2017) The Intra-S Checkpoint Responses to DNA Damage. Genes 8:2, pages 74.
Crossref
Crossref
Sriganesh Srihari, Murugan Kalimutho, Samir Lal, Jitin Singla, Dhaval Patel, Peter T. Simpson, Kum Kum Khanna & Mark A. Ragan. (2016) Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach. Molecular BioSystems 12:3, pages 963-972.
Crossref
Crossref
Gunjan Piya, Erica N. Mueller, Heather K. Haas, Padmaja L. Ghospurkar, Timothy M. Wilson, Jaime L. Jensen, Christopher L. Colbert & Stuart J. Haring. (2015) Characterization of the Interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. PLOS ONE 10:2, pages e0116512.
Crossref
Crossref
Alexandre Maréchal & Lee Zou. (2014) RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Research 25:1, pages 9-23.
Crossref
Crossref
R.S. Pavani, C. Fernandes, A.M. Perez, E.J.R. Vasconcelos, J.L. Siqueira-Neto, M.R. Fontes & M.I.N. Cano. (2014)
RPA-1 from
Leishmania amazonensis
(LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain
. FEBS Letters 588:24, pages 4740-4748.
Crossref
Crossref
Jun Xiang, Lekun Fang, Yanxin Luo, Zuli Yang, Yi Liao, Ji Cui, Meijin Huang, Zihuan Yang, Yan Huang, Xinjuan Fan, Huashe Wang, Lei Wang, Junsheng Peng & Jianping Wang. (2014) Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer. Journal of Translational Medicine 12:1.
Crossref
Crossref
Huimin Shen, Muyan Cai, Shanshan Zhao, Huan Wang, Mengxiong Li, Shuzhong Yao & Nan Jiang. (2014) Overexpression of RFC3 is correlated with ovarian tumor development and poor prognosis. Tumor Biology 35:10, pages 10259-10266.
Crossref
Crossref
Nicole Hustedt, Susan Gasser & Kenji Shimada. (2013) Replication Checkpoint: Tuning and Coordination of Replication Forks in S Phase. Genes 4:3, pages 388-434.
Crossref
Crossref
Mafumi Abiko, Kensyo Furuta, Yoshio Yamauchi, Chiharu Fujita, Masato Taoka, Toshiaki Isobe & Takashi Okamoto. (2013) Identification of Proteins Enriched in Rice Egg or Sperm Cells by Single-Cell Proteomics. PLoS ONE 8:7, pages e69578.
Crossref
Crossref
Nathalie Grandin & Michel Charbonneau. (2013) RPA provides checkpoint-independent cell cycle arrest and prevents recombination at uncapped telomeres of Saccharomyces cerevisiae. DNA Repair 12:3, pages 212-226.
Crossref
Crossref
Jason G. Glanzer, Katie A. Carnes, Patricia Soto, Shengqin Liu, Lawrence J. Parkhurst & Gregory G. Oakley. (2013) A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A. Nucleic Acids Research 41:3, pages 2047-2059.
Crossref
Crossref
Karen Kuntz & Matthew J O’Connell. (2012) Initiation of DNA damage responses through XPG-related nucleases. The EMBO Journal 32:2, pages 290-302.
Crossref
Crossref
Laura A. Lindsey-Boltz, Joyce T. Reardon, Marc S. Wold & Aziz Sancar. (2012) In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling. Journal of Biological Chemistry 287:43, pages 36123-36131.
Crossref
Crossref
Bamaprasad Dutta, Sunil S. Adav, Cheng Gee Koh, Sai Kiang Lim, Eran Meshorer & Siu Kwan Sze. (2012) Elucidating the temporal dynamics of chromatin-associated protein release upon DNA digestion by quantitative proteomic approach. Journal of Proteomics 75:17, pages 5493-5506.
Crossref
Crossref
Aishwarya Prakash & Gloria E. O. Borgstahl. 2012. The Eukaryotic Replisome: a Guide to Protein Structure and Function. The Eukaryotic Replisome: a Guide to Protein Structure and Function
171
196
.
Jason G. Glanzer, Shengqin Liu & Gregory G. Oakley. (2011) Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods. Bioorganic & Medicinal Chemistry 19:8, pages 2589-2595.
Crossref
Crossref
Fabio Vanoli, Marco Fumasoni, Barnabas Szakal, Laurent Maloisel & Dana Branzei. (2010) Replication and Recombination Factors Contributing to Recombination-Dependent Bypass of DNA Lesions by Template Switch. PLoS Genetics 6:11, pages e1001205.
Crossref
Crossref
Jun-Hyuk Choi, Laura A. Lindsey-Boltz, Michael Kemp, Aaron C. Mason, Marc S. Wold & Aziz Sancar. (2010) Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proceedings of the National Academy of Sciences 107:31, pages 13660-13665.
Crossref
Crossref
Cathy S. Hass, Lokesh Gakhar & Marc S. Wold. (2010) Functional Characterization of a Cancer Causing Mutation in Human Replication Protein A. Molecular Cancer Research 8:7, pages 1017-1026.
Crossref
Crossref
Craig B. Bennett. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling
2145
2158
.
Tomohiko Sugiyama & Noriko Kantake. (2009) Dynamic Regulatory Interactions of Rad51, Rad52, and Replication Protein-A in Recombination Intermediates. Journal of Molecular Biology 390:1, pages 45-55.
Crossref
Crossref
Masaaki Arai, Nobuo Kondoh, Nobuo Imazeki, Akiyuki Hada, Kazuo Hatsuse, Osamu Matsubara & Mikio Yamamoto. (2009) The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. Liver International 29:1, pages 55-62.
Crossref
Crossref
Daniel A. Mordes & David Cortez. 2009. The DNA Damage Response: Implications on Cancer Formation and Treatment. The DNA Damage Response: Implications on Cancer Formation and Treatment
25
45
.
Sara K. Binz & Marc S. Wold. (2008) Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA). Journal of Biological Chemistry 283:31, pages 21559-21570.
Crossref
Crossref
Stuart J. Haring, Aaron C. Mason, Sara K. Binz & Marc S. Wold. (2008) Cellular Functions of Human RPA1. Journal of Biological Chemistry 283:27, pages 19095-19111.
Crossref
Crossref
Junya Tomida, Yuji Masuda, Hidekazu Hiroaki, Tomoko Ishikawa, Ihnyoung Song, Toshiki Tsurimoto, Satoshi Tateishi, Tadahiro Shiomi, Yasuhiro Kamei, Jinhyeong Kim, Kenji Kamiya, Cyrus Vaziri, Haruo Ohmori & Takeshi Todo. (2008) DNA Damage-induced Ubiquitylation of RFC2 Subunit of Replication Factor C Complex. Journal of Biological Chemistry 283:14, pages 9071-9079.
Crossref
Crossref
Jacqueline H. Barlow, Michael Lisby & Rodney Rothstein. (2008) Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1. Molecular Cell 30:1, pages 73-85.
Crossref
Crossref
Miki Ii, Tatsuya Ii & Steven J. Brill. (2007) Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 625:1-2, pages 1-19.
Crossref
Crossref
Mark O’Driscoll, William B. Dobyns, Johanna M. van Hagen & Penny A. Jeggo. (2007) Cellular and Clinical Impact of Haploinsufficiency for Genes Involved in ATR Signaling. The American Journal of Human Genetics 81:1, pages 77-86.
Crossref
Crossref
Michael Lisby & Rodney Rothstein. 2007. Molecular Genetics of Recombination. Molecular Genetics of Recombination
317
333
.
Christian Rudolph, K. Anke Schürer & Wilfried Kramer. 2007. Genome Integrity. Genome Integrity
105
152
.
Tomohiko Sugiyama, Noriko Kantake, Yun Wu & Stephen C Kowalczykowski. (2006) Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture. The EMBO Journal 25:23, pages 5539-5548.
Crossref
Crossref
Jerzy Majka, Sara K. Binz, Marc S. Wold & Peter M.J. Burgers. (2006) Replication Protein A Directs Loading of the DNA Damage Checkpoint Clamp to 5′-DNA Junctions. Journal of Biological Chemistry 281:38, pages 27855-27861.
Crossref
Crossref
Andrew P. VanDemark, Mary Blanksma, Elliott Ferris, Annie Heroux, Christopher P. Hill & Tim Formosa. (2006) The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition. Molecular Cell 22:3, pages 363-374.
Crossref
Crossref
J.M. Cardone, L.F. Revers, R.M. Machado, D. Bonatto, M. Brendel & J.A.P. Henriques. (2006) Psoralen-sensitive mutant pso9-1 of Saccharomyces cerevisiae contains a mutant allele of the DNA damage checkpoint gene MEC3. DNA Repair 5:2, pages 163-171.
Crossref
Crossref
Xiaohong H. Yang & Lee Zou. 2006. Cell Cycle Regulation. Cell Cycle Regulation
65
92
.
Soo-Mi Kim, Akiko Kumagai, Joon Lee & William G. Dunphy. (2005) Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus Egg Extracts Requires Binding of ATRIP to ATR but Not the Stable DNA-binding or Coiled-coil Domains of ATRIP. Journal of Biological Chemistry 280:46, pages 38355-38364.
Crossref
Crossref
Yuxun Wang, Christopher D Putnam, Michael F Kane, Weijia Zhang, Lisa Edelmann, Robert Russell, Danaise V Carrión, Lynda Chin, Raju Kucherlapati, Richard D Kolodner & Winfried Edelmann. (2005) Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nature Genetics 37:7, pages 750-755.
Crossref
Crossref
David Cortez. (2005) Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling: Figure 1.. Genes & Development 19:9, pages 1007-1012.
Crossref
Crossref
Matthew J. O'Connell & Karlene A. Cimprich. (2005) G2 damage checkpoints: what is the turn-on?. Journal of Cell Science 118:1, pages 1-6.
Crossref
Crossref
Michael Lisby, Jacqueline H. Barlow, Rebecca C. Burgess & Rodney Rothstein. (2004) Choreography of the DNA Damage Response. Cell 118:6, pages 699-713.
Crossref
Crossref
Edgardo R. Parrilla-Castellar, Sonnet J.H. Arlander & Larry Karnitz. (2004) Dial 9–1–1 for DNA damage: the Rad9–Hus1–Rad1 (9–1–1) clamp complex. DNA Repair 3:8-9, pages 1009-1014.
Crossref
Crossref
Yinhuai Chen & Yolanda Sanchez. (2004) Chk1 in the DNA damage response: conserved roles from yeasts to mammals. DNA Repair 3:8-9, pages 1025-1032.
Crossref
Crossref
Hee-Sook Kim & Steven J. Brill. (2003) MEC1-dependent phosphorylation of yeast RPA1 in vitro. DNA Repair 2:12, pages 1321-1335.
Crossref
Crossref
Lee Zou, Dou Liu & Stephen J. Elledge. (2003) Replication protein A-mediated recruitment and activation of Rad17 complexes. Proceedings of the National Academy of Sciences 100:24, pages 13827-13832.
Crossref
Crossref
Viola Ellison & Bruce Stillman. (2003) Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA. PLoS Biology 1:2, pages e33.
Crossref
Crossref
Sara K. Binz, Ye Lao, David F. Lowry & Marc S. Wold. (2003) The Phosphorylation Domain of the 32-kDa Subunit of Replication Protein A (RPA) Modulates RPA-DNA Interactions. Journal of Biological Chemistry 278:37, pages 35584-35591.
Crossref
Crossref
Lee ZouStephen J. Elledge. (2003) Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes. Science 300:5625, pages 1542-1548.
Crossref
Crossref
Amnon Koren, Shay Ben-Aroya, Rivka Steinlauf & Martin Kupiec. (2003) Pitfalls of the synthetic lethality screen in Saccharomyces cerevisiae: an improved design. Current Genetics 43:1, pages 62-69.
Crossref
Crossref
Mauricio Menacho Márquez & José Ramón Murguía Ibáñez. (2003) DNA damage signalling in eukaryotes: learning from budding yeastSeñalización del daño al ADN en eucariotas: aprendiendo de la levadura de gemación. Revista de Oncología 5:3, pages 139-147.
Crossref
Crossref
Andrew R. Cuddihy & Matthew J. O'Connell. 2003.
99
140
.
Craig B. Bennett & Michael A. Resnick. 2003. Handbook of Cell Signaling. Handbook of Cell Signaling
203
211
.
Kenji Shimada, Philippe Pasero & Susan M. Gasser. (2002) ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes & Development 16:24, pages 3236-3252.
Crossref
Crossref
Kara A. NybergRhett J. MichelsonCharles W. PutnamTed A. Weinert. (2002) Toward Maintaining the Genome: DNA Damage and Replication Checkpoints. Annual Review of Genetics 36:1, pages 617-656.
Crossref
Crossref
Christine Soustelle, Michèle Vedel, Richard Kolodner & Alain Nicolas. (2002)
Replication Protein A Is Required for Meiotic Recombination in
Saccharomyces cerevisiae
. Genetics 161:2, pages 535-547.
Crossref
Crossref
Kyungjae Myung & Richard D. Kolodner. (2002)
Suppression of genome instability by redundant S-phase checkpoint pathways in
Saccharomyces
cerevisiae
. Proceedings of the National Academy of Sciences 99:7, pages 4500-4507.
Crossref
Crossref
Thomas J Oakley & Ian D Hickson. (2002) Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III. DNA Repair 1:3, pages 175-207.
Crossref
Crossref
Shawn Ahmed, Arno Alpi, Michael O. Hengartner & Anton Gartner. (2001) C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein. Current Biology 11:24, pages 1934-1944.
Crossref
Crossref
. (2001) Current Awareness. Yeast 18:13, pages 1269-1276.
Crossref
Crossref
Suzanne A. Bastin-Shanower & Steven J. Brill. (2001) Functional Analysis of the Four DNA Binding Domains of Replication Protein A. Journal of Biological Chemistry 276:39, pages 36446-36453.
Crossref
Crossref