Citations (56)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Ethan R Fitzpatrick, Tinghui Hu, Bryan T Ciccarelli & Ian P Whitehead. (2014) Regulation of vesicle transport and cell motility by Golgi-localized Dbs. Small GTPases 5:4.
Read now
Read now
Elena Kamynina, Krista Kauppinen, Faping Duan, Nora Muakkassa & Danny Manor. (2007) Regulation of Proto-Oncogenic Dbl by Chaperone-Controlled, Ubiquitin-Mediated Degradation. Molecular and Cellular Biology 27:5, pages 1809-1822.
Read now
Read now
Michael J. Hamann, Casey M. Lubking, Doris N. Luchini & Daniel D. Billadeau. (2007) Asef2 Functions as a Cdc42 Exchange Factor and Is Stimulated by the Release of an Autoinhibitory Module from a Concealed C-Terminal Activation Element. Molecular and Cellular Biology 27:4, pages 1380-1393.
Read now
Read now
Emilio Hirsch, Michela Pozzato, Alessandro Vercelli, Laura Barberis, Ornella Azzolino, Chiara Russo, Cristina Vanni, Lorenzo Silengo, Alessandra Eva & Fiorella Altruda. (2002) Defective Dendrite Elongation but Normal Fertility in Mice Lacking the Rho-Like GTPase Activator Dbl. Molecular and Cellular Biology 22:9, pages 3140-3148.
Read now
Read now
Articles from other publishers (52)
Takefumi Sugiyama, Haruka Yamamoto, Tetsuo Kon, Taro Chaya, Yoshihiro Omori, Yutaka Suzuki, Kentaro Abe, Dai Watanabe & Takahisa Furukawa. (2020) The potential role of Arhgef33 RhoGEF in foveal development in the zebra finch retina. Scientific Reports 10:1.
Crossref
Crossref
Xiuran Niu, Linjia Su, Shanshan Qi, Zhihui Gao, Qing Zhang & Sihe Zhang. (2018) GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway. Cell Death & Disease 9:10.
Crossref
Crossref
Yujie Li, Sandra Finkbeiner, Athina Ganner, Julia Gerber, Marinella Klein, Manuel Grafe, Jakob Kandzia, Antje Thien, Kathrin Thedieck, Gerhard Breves, Thomas Jank, Ralf Baumeister, Gerd Walz & Elke Neumann-Haefelin. (2018)
CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in
C. elegans
. Oncotarget 9:11, pages 9581-9595.
Crossref
Crossref
Ivan K. Popov, Heather J. Ray, Paul Skoglund, Ray Keller & Chenbei Chang. (2018) The RhoGEF protein Plekhg5 regulates apical constriction of bottle cells during gastrulation. Development.
Crossref
Crossref
Di Wu, Meng Jiao, Shicheng Zu, Christopher C. Sollecito, Kevin Jimenez-Cowell, Alexander J. Mold, Ryan M. Kennedy & Qize Wei. (2014) Intramolecular Interactions between the Dbl Homology (DH) Domain and the Carboxyl-terminal region of Myosin II-interacting Guanine Nucleotide Exchange Factor (MyoGEF) Act as an Autoinhibitory Mechanism for the Regulation of MyoGEF Functions. Journal of Biological Chemistry 289:49, pages 34033-34048.
Crossref
Crossref
Xinxin WangScott E. BoykenJiancheng HuXiaolu XuRyan P. RimerMadeline A. SheaAndrey S. ShawAmy H. AndreottiYina H. Huang. (2014)
Calmodulin and PI(3,4,5)P
3
cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production
. Science Signaling 7:337.
Crossref
Crossref
Meghana Gupta, Xiaojun Qi, Varsha Thakur & Danny Manor. (2014) Tyrosine Phosphorylation of Dbl Regulates GTPase Signaling. Journal of Biological Chemistry 289:24, pages 17195-17202.
Crossref
Crossref
Marzia Ognibene, Cristina Vanni, Fabiola Blengio, Daniela Segalerba, Patrizia Mancini, Patrizia De Marco, Maria R. Torrisi, Maria C. Bosco, Luigi Varesio & Alessandra Eva. (2014) Identification of a novel mouse Dbl proto-oncogene splice variant: Evidence that SEC14 domain is involved in GEF activity regulation. Gene 537:2, pages 220-229.
Crossref
Crossref
Yukako Oda, Tetsuhisa Otani, Junichi Ikenouchi & Mikio Furuse. (2014) Tricellulin regulates junctional tension of epithelial cells at tricellular contacts via Cdc42. Journal of Cell Science.
Crossref
Crossref
Christina R. Chow, Nobuchika Suzuki, Takeshi Kawamura, Takao Hamakubo & Tohru Kozasa. (2013) Modification of p115RhoGEF Ser330 regulates its RhoGEF activity. Cellular Signalling 25:11, pages 2085-2092.
Crossref
Crossref
Meghana Gupta, Elena Kamynina, Samantha Morley, Stacey Chung, Nora Muakkassa, Hong Wang, Shayna Brathwaite, Gaurav Sharma & Danny Manor. (2013) Plekhg4 Is a Novel Dbl Family Guanine Nucleotide Exchange Factor Protein for Rho Family GTPases. Journal of Biological Chemistry 288:20, pages 14522-14530.
Crossref
Crossref
Li Lin, Thuy Tran, Shuang Hu, Todd Cramer, Richard Komuniecki & Robert M. Steven. (2012) RHGF-2 Is an Essential Rho-1 Specific RhoGEF that binds to the Multi-PDZ Domain Scaffold Protein MPZ-1 in Caenorhabditis elegans. PLoS ONE 7:2, pages e31499.
Crossref
Crossref
Robert C. Orchard, Mark Kittisopikul, Steven J. Altschuler, Lani F. Wu, Gürol M. Süel & Neal M. Alto. (2012) Identification of F-actin as the Dynamic Hub in a Microbial-Induced GTPase Polarity Circuit. Cell 148:4, pages 803-815.
Crossref
Crossref
Taro Chaya, Satoshi Shibata, Yasunori Tokuhara, Wataru Yamaguchi, Hiroshi Matsumoto, Ichiro Kawahara, Mikihiko Kogo, Yoshiharu Ohoka & Shinobu Inagaki. (2011) Identification of a Negative Regulatory Region for the Exchange Activity and Characterization of T332I Mutant of Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10). Journal of Biological Chemistry 286:34, pages 29511-29520.
Crossref
Crossref
Ramesh M. Ray, Mitulkumar N. Bavaria, Sujoy Bhattacharya & Leonard R. Johnson. (2011) Activation of Dbl restores migration in polyamine-depleted intestinal epithelial cells via Rho-GTPases. American Journal of Physiology-Gastrointestinal and Liver Physiology 300:6, pages G988-G997.
Crossref
Crossref
Marzia Ognibene, Ottavia Barbieri, Cristina Vanni, Luca Mastracci, Simonetta Astigiano, Laura Emionite, Barbara Salani, Manuela Fedele, Roberta Resaz, Claudya Tenca, Franco Fais, Federica Sabatini, Amleto De Santanna, Fiorella Altruda, Luigi Varesio, Emilio Hirsch & Alessandra Eva. (2011) High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice. Journal of Molecular Medicine 89:5, pages 493-504.
Crossref
Crossref
Xiaojian Xu, Tatiana Omelchenko & Alan Hall. (2010) LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity. BMC Cell Biology 11:1.
Crossref
Crossref
Yi Ting Zhou, Li Li Chew, Sheng-cai Lin & Boon Chuan Low. (2010) The BNIP-2 and Cdc42GAP Homology (BCH) Domain of p50RhoGAP/Cdc42GAP Sequesters RhoA from Inactivation by the Adjacent GTPase-activating Protein Domain. Molecular Biology of the Cell 21:18, pages 3232-3246.
Crossref
Crossref
K. Farid Ahmad & Wendell A. Lim. (2010) The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin. PLoS ONE 5:6, pages e11291.
Crossref
Crossref
Qiyu Feng & Richard A. Cerione. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling
1785
1794
.
Meiying Zheng, Tomasz Cierpicki, Ko Momotani, Mykhaylo V Artamonov, Urszula Derewenda, John H Bushweller, Avril V Somlyo & Zygmunt S Derewenda. (2009) On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. BMC Structural Biology 9:1.
Crossref
Crossref
Daisuke Urano, Asuka Nakata, Norikazu Mizuno, Kenji Tago & Hiroshi Itoh. (2008) Domain–domain interaction of P-Rex1 is essential for the activation and inhibition by G protein βγ subunits and PKA. Cellular Signalling 20:8, pages 1545-1554.
Crossref
Crossref
Masanao Murakami, Patricio I. Meneses, Jason S. Knight, Ke Lan, Rajeev Kaul, Subhash C. Verma & Erle S. Robertson. (2008) Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. International Journal of Cancer 123:3, pages 500-510.
Crossref
Crossref
Cyril Mionnet, Stéphanie Bogliolo & Robert A. Arkowitz. (2008) Oligomerization Regulates the Localization of Cdc24, the Cdc42 Activator in Saccharomyces cerevisiae. Journal of Biological Chemistry 283:25, pages 17515-17530.
Crossref
Crossref
Aline Appert-Collin, Susanna Cotecchia, Monique Nenniger-Tosato, Thierry Pedrazzini & Dario Diviani. (2007) The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates α1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proceedings of the National Academy of Sciences 104:24, pages 10140-10145.
Crossref
Crossref
S. Morley, J. Wagner, K. Kauppinen, M. Sherman & D. Manor. (2007) Requirement for Akt-mediated survival in cell transformation by the dbl oncogene. Cellular Signalling 19:1, pages 211-218.
Crossref
Crossref
Martin R. Schiller. (2006) Coupling receptor tyrosine kinases to Rho GTPases—GEFs what's the link. Cellular Signalling 18:11, pages 1834-1843.
Crossref
Crossref
Martin R. Schiller, Kausik Chakrabarti, Glenn F. King, Noraisha I. Schiller, Betty A. Eipper & Mark W. Maciejewski. (2006) Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions. Journal of Biological Chemistry 281:27, pages 18774-18786.
Crossref
Crossref
Dario Diviani, Laurent Baisamy & Aline Appert-Collin. (2006) AKAP-Lbc: A molecular scaffold for the integration of cyclic AMP and Rho transduction pathways. European Journal of Cell Biology 85:7, pages 603-610.
Crossref
Crossref
Michael Wirtenberger, Sandrine Tchatchou, Kari Hemminki, Rüdiger Klaes, Rita K. Schmutzler, Justo L. Bermejo, Bowang Chen, Barbara Wappenschmidt, Alfons Meindl, Claus R. Bartram & Barbara Burwinkel. (2006) Association of genetic variants in the Rho guanine nucleotide exchange factor AKAP13 with familial breast cancer. Carcinogenesis 27:3, pages 593-598.
Crossref
Crossref
Sze-Wah Tse, Jennifer A. Broderick, Mei-Ling Wei, Min-Hua Luo, Deborah Smith, Peter McCaffery, Stefan Stamm & Athena Andreadis. (2005) Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain. Gene 359, pages 63-72.
Crossref
Crossref
Krista P. Kauppinen, Faping Duan, Jared I. Wels & Danny Manor. (2005) Regulation of the Dbl Proto-oncogene by Heat Shock Cognate Protein 70 (Hsc70). Journal of Biological Chemistry 280:22, pages 21638-21644.
Crossref
Crossref
Laurent Baisamy, Nathalie Jurisch & Dario Diviani. (2005) Leucine Zipper-mediated Homo-oligomerization Regulates the Rho-GEF Activity of AKAP-Lbc. Journal of Biological Chemistry 280:15, pages 15405-15412.
Crossref
Crossref
Huajun Qin, Heather S. Carr, Xiaochong Wu, Daniella Muallem, Nancy H. Tran & Jeffrey A. Frost. (2005) Characterization of the Biochemical and Transforming Properties of the Neuroepithelial Transforming Protein 1. Journal of Biological Chemistry 280:9, pages 7603-7613.
Crossref
Crossref
Ja-Eun Kim, Daniel D. Billadeau & Junjie Chen. (2005) The Tandem BRCT Domains of Ect2 Are Required for Both Negative and Positive Regulation of Ect2 in Cytokinesis. Journal of Biological Chemistry 280:7, pages 5733-5739.
Crossref
Crossref
Elena V. Kostenko, Gwendolyn M. Mahon, Li Cheng & Ian P. Whitehead. (2005) The Sec14 Homology Domain Regulates the Cellular Distribution and Transforming Activity of the Rho-specific Guanine Nucleotide Exchange Factor Dbs. Journal of Biological Chemistry 280:4, pages 2807-2817.
Crossref
Crossref
Jong-Hwan Lee, Tomoya Katakai, Takahiro Hara, Hiroyuki Gonda, Manabu Sugai & Akira Shimizu. (2004) Roles of p-ERM and Rho–ROCK signaling in lymphocyte polarity and uropod formation. Journal of Cell Biology 167:2, pages 327-337.
Crossref
Crossref
Jayashree Banerjee & Philip B. Wedegaertner. (2004) Identification of a Novel Sequence in PDZ-RhoGEF That Mediates Interaction with the Actin Cytoskeleton. Molecular Biology of the Cell 15:4, pages 1760-1775.
Crossref
Crossref
Min Lin & Kenneth L. van Golen. (2004) Rho-Regulatory Proteins in Breast Cancer Cell Motility and Invasion. Breast Cancer Research and Treatment 84:1, pages 49-60.
Crossref
Crossref
Mark B. Klinger, Benoit Guilbault & Robert J. Kay. (2004) The RhoA- and CDC42-specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double-positive and single-positive thymocytes. European Journal of Immunology 34:3, pages 806-816.
Crossref
Crossref
Parmesh Dutt, Nhan Nguyen & Deniz Toksoz. (2004) Role of Lbc RhoGEF in Gα12/13-induced signals to Rho GTPase. Cellular Signalling 16:2, pages 201-209.
Crossref
Crossref
Jinbin Zhai, Hong Lin, Zhenying Nie, Junhua Wu, Rafaela Cañete-Soler, William W. Schlaepfer & David D. Schlaepfer. (2003) Direct Interaction of Focal Adhesion Kinase with p190RhoGEF. Journal of Biological Chemistry 278:27, pages 24865-24873.
Crossref
Crossref
Rocı́o Jorge, Natasha Zarich, José Luis Oliva, Marta Azañedo, Natalia Martı́nez, Xavier de la Cruz & José M. Rojas. (2002) hSos1 Contains a New Amino-terminal Regulatory Motif with Specific Binding Affinity for Its Pleckstrin Homology Domain. Journal of Biological Chemistry 277:46, pages 44171-44179.
Crossref
Crossref
Naoyuki Yabana & Masabumi Shibuya. (2002) Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity. Oncogene 21:50, pages 7720-7729.
Crossref
Crossref
Malgorzata Korus, Gwendolyn M Mahon, Li Cheng & Ian P Whitehead. (2002) p38 MAPK-mediated activation of NF-κB by the RhoGEF domain of Bcr. Oncogene 21:30, pages 4601-4612.
Crossref
Crossref
Anja Schmidt & Alan Hall. (2002) Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes & Development 16:13, pages 1587-1609.
Crossref
Crossref
Cristina Vanni, Patrizia Mancini, Yuan Gao, Catherine Ottaviano, Fukun Guo, Barbara Salani, Maria Rosaria Torrisi, Yi Zheng & Alessandra Eva. (2002) Regulation of Proto-Dbl by Intracellular Membrane Targeting and Protein Stability. Journal of Biological Chemistry 277:22, pages 19745-19753.
Crossref
Crossref
Anja Schmidt & Alan Hall. (2002) The Rho Exchange Factor Net1 Is Regulated by Nuclear Sequestration. Journal of Biological Chemistry 277:17, pages 14581-14588.
Crossref
Crossref
Hiroki Chikumi, Shigetomo Fukuhara & J. Silvio Gutkind. (2002) Regulation of G Protein-linked Guanine Nucleotide Exchange Factors for Rho, PDZ-RhoGEF, and LARG by Tyrosine Phosphorylation. Journal of Biological Chemistry 277:14, pages 12463-12473.
Crossref
Crossref
Gregory R Hoffman & Richard A Cerione. (2002) Signaling to the Rho GTPases: networking with the DH domain. FEBS Letters 513:1, pages 85-91.
Crossref
Crossref
Yi Zheng. (2001) Dbl family guanine nucleotide exchange factors. Trends in Biochemical Sciences 26:12, pages 724-732.
Crossref
Crossref
Dario Diviani, Jacquelyn Soderling & John D. Scott. (2001) AKAP-Lbc Anchors Protein Kinase A and Nucleates Gα12-selective Rho-mediated Stress Fiber Formation. Journal of Biological Chemistry 276:47, pages 44247-44257.
Crossref
Crossref