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Molecular and Cellular Biology Volume 21, 2001 - Issue 5
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Gene Expression

Ambient pH Signaling Regulates Nuclear Localization of the Aspergillus nidulans PacC Transcription Factor

José M. MingotCentro de Investigaciones Biológicas CSIC, Madrid28006, Spain
,
Eduardo A. EspesoCentro de Investigaciones Biológicas CSIC, Madrid28006, Spain
,
Eliecer Dı́ezCentro de Investigaciones Biológicas CSIC, Madrid28006, Spain
&
MiguelÁ. PeñalvaCentro de Investigaciones Biológicas CSIC, Madrid28006, SpainCorrespondence[email protected]
Pages 1688-1699 | Received 10 Aug 2000, Accepted 07 Dec 2000, Published online: 28 Mar 2023

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Dov Prusky, Shiri Barad, Dana Ment & Fangcheng Bi. (2016) The pH modulation by fungal secreted molecules: a mechanism affecting pathogenicity by postharvest pathogens. Israel Journal of Plant Sciences 63:1, pages 22-30.
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Teresa R. O'Meara, Wenjie Xu, Kyla M. Selvig, Matthew J. O'Meara, Aaron P. Mitchell & J. Andrew Alspaugh. (2014) The Rim101 Transcription Factor Directly Regulates Genes Required for Adaptation to the Host. Molecular and Cellular Biology 34:4, pages 673-684.
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Olivier Vincent, Lynne Rainbow, Joan Tilburn, Herbert N. Arst$suffix/text()$suffix/text() & Miguel A. Peñalva. (2003) YPXL/I Is a Protein Interaction Motif Recognized by Aspergillus PalA and Its Human Homologue, AIP1/Alix. Molecular and Cellular Biology 23:5, pages 1647-1655.
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Teresa M. Lamb & Aaron P. Mitchell. (2003) The Transcription Factor Rim101p Governs Ion Tolerance and Cell Differentiation by Direct Repression of the Regulatory Genes NRG1 and SMP1 in Saccharomyces cerevisiae. Molecular and Cellular Biology 23:2, pages 677-686.
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Articles from other publishers (48)

Boqiang Li, Yong Chen & Shiping Tian. (2021) Function of pH‐dependent transcription factor PacC in regulating development, pathogenicity, and mycotoxin biosynthesis of phytopathogenic fungi. The FEBS Journal 289:7, pages 1723-1730.
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Wenxiao Jiao, Xin Liu, Youyuan Li, Boqiang Li, Yamin Du, Zhanquan Zhang, Qingmin Chen & Maorun Fu. (2021) Organic acid, a virulence factor for pathogenic fungi, causing postharvest decay in fruits. Molecular Plant Pathology 23:2, pages 304-312.
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Héctor Toledo, Clara Inés Sánchez, Laura Marín, Jorge Amich & José Antonio Calera. (2021) Regulation of zinc homeostatic genes by environmental pH in the filamentous fungus Aspergillus fumigatus . Environmental Microbiology 24:2, pages 643-666.
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Carelle Kouasseu Jimdjio, Huali Xue, Yang Bi, Mina Nan, Lan Li, Rui Zhang, Qili Liu & Lumei Pu. (2021) Effect of Ambient pH on Growth, Pathogenicity, and Patulin Production of Penicillium expansum. Toxins 13:8, pages 550.
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Christelle El Hajj Assaf, Chrystian Zetina-Serrano, Nadia Tahtah, André El Khoury, Ali Atoui, Isabelle P. Oswald, Olivier Puel & Sophie Lorber. (2020) Regulation of Secondary Metabolism in the Penicillium Genus. International Journal of Molecular Sciences 21:24, pages 9462.
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Andreas Schüller, Lisa Wolansky, Harald Berger, Lena Studt, Agnieszka Gacek-Matthews, Michael Sulyok & Joseph Strauss. (2020) A novel fungal gene regulation system based on inducible VPR-dCas9 and nucleosome map-guided sgRNA positioning. Applied Microbiology and Biotechnology 104:22, pages 9801-9822.
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C Snyman, LW Theron & B Divol. (2019) Understanding the regulation of extracellular protease gene expression in fungi: a key step towards their biotechnological applications. Applied Microbiology and Biotechnology 103:14, pages 5517-5532.
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Weili Gong, Lin Dai, Huaiqiang Zhang, Lili Zhang & Lushan Wang. (2018) A Highly Efficient Xylan-Utilization System in Aspergillus niger An76: A Functional-Proteomics Study. Frontiers in Microbiology 9.
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Zhibing Luo, Hui Ren, Jarrod J. Mousa, Drauzio E. N. Rangel, Yongjun Zhang, Steven D. Bruner & Nemat O. Keyhani. (2017) The PacC transcription factor regulates secondary metabolite production and stress response, but has only minor effects on virulence in the insect pathogenic fungus Beauveria bassiana . Environmental Microbiology 19:2, pages 788-802.
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Jing Zhu, Sheng-Hua Ying & Ming-Guang Feng. (2016) The Pal pathway required for ambient pH adaptation regulates growth, conidiation, and osmotolerance of Beauveria bassiana in a pH-dependent manner. Applied Microbiology and Biotechnology 100:10, pages 4423-4433.
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Shiri Barad, Edward Sionov & Dov Prusky. (2016) Role of patulin in post-harvest diseases. Fungal Biology Reviews 30:1, pages 24-32.
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Henk‐Jan Bussink, Elaine M. Bignell, Tatiana Múnera‐Huertas, Daniel Lucena‐Agell, Claudio Scazzocchio, Eduardo A. Espeso, Margherita Bertuzzi, Joanna Rudnicka, Susana Negrete‐Urtasun, Maria M. Peñas‐Parilla, Lynne Rainbow, Miguel Á. Peñalva, Herbert N. ArstJr.Jr. & Joan Tilburn. (2015) Refining the pH response in A spergillus nidulans : a modulatory triad involving PacX , a novel zinc binuclear cluster protein . Molecular Microbiology 98:6, pages 1051-1072.
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Yonathan Lukito, Tetsuya Chujo & Barry Scott. (2015) Molecular and cellular analysis of the pH response transcription factor PacC in the fungal symbiont Epichloë festucae. Fungal Genetics and Biology 85, pages 25-37.
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Erika Herrero-Garcia, Elixabet Perez-de-Nanclares-Arregi, Marc S. Cortese, Ane Markina-Iñarrairaegui, Elixabet Oiartzabal-Arano, Oier Etxebeste, Unai Ugalde & Eduardo A. Espeso. (2015) Tip-to-nucleus migration dynamics of the asexual development regulator FlbB in vegetative cells. Molecular Microbiology 98:4, pages 607-624.
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Yi Lou, Yongchao Han, Long Yang, Mingde Wu, Jing Zhang, Jiasen Cheng, Moying Wang, Daohong Jiang, Weidong Chen & Guoqing Li. (2015) CmpacC regulates mycoparasitism, oxalate degradation and antifungal activity in the mycoparasitic fungus C oniothyrium minitans . Environmental Microbiology 17:11, pages 4711-4729.
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Lourdes Baeza-Montañez, Scott E. Gold, Eduardo A. Espeso & María D. García-Pedrajas. (2015) Conserved and Distinct Functions of the “Stunted” (StuA)-Homolog Ust1 During Cell Differentiation in the Corn Smut Fungus Ustilago maydis . Molecular Plant-Microbe Interactions® 28:1, pages 86-102.
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Joanna Tannous, Rhoda El Khoury, Selma P. Snini, Yannick Lippi, André El Khoury, Ali Atoui, Roger Lteif, Isabelle P. Oswald & Olivier Puel. (2014) Sequencing, physical organization and kinetic expression of the patulin biosynthetic gene cluster from Penicillium expansum. International Journal of Food Microbiology 189, pages 51-60.
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Cameron C. Hunter, Kendra S. Siebert, Damien J. Downes, Koon Ho Wong, Sara D. Kreutzberger, James A. Fraser, David F. Clarke, Michael J. Hynes, Meryl A. Davis & Richard B. Todd. (2014) Multiple Nuclear Localization Signals Mediate Nuclear Localization of the GATA Transcription Factor AreA. Eukaryotic Cell 13:4, pages 527-538.
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Yong-Hong Zhou, Lei Hou, Yong-Jun Zhang, Yan-Hua Fan, Zhi-Bing Luo, Dan Jin, Qiao-Sheng Zhou, Yu-Jie Li, You Wang & Yan Pei. (2014) Expression and promoter characterization of BbPacC, a pH response transcription factor gene of the entomopathogenic fungus Beauveria bassiana. Microbiology 160:2, pages 353-361.
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Motoaki Sano, Akiko Kobayashi & Shinichi Ohashi. (2014) Characterization of the palF gene from Aspergillus oryzae. Journal of Biological Macromolecules 14:3, pages 125-132.
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Antonio Rossi, Aline H. S. Cruz, Rodrigo S. Santos, Patrícia M. Silva, Emiliana M. Silva, Niege S. Mendes & Nilce M. Martinez-Rossi. (2013) Ambient pH sensing in filamentous fungi: Pitfalls in elucidating regulatory hierarchical signaling networks. IUBMB Life 65:11, pages 930-935.
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Noam AlkanEduardo A. EspesoDov Prusky. (2013) Virulence Regulation of Phytopathogenic Fungi by pH. Antioxidants & Redox Signaling 19:9, pages 1012-1025.
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Patricia Hernández-Ortiz & Eduardo A. Espeso. (2013) Phospho-regulation and nucleocytoplasmic trafficking of CrzA in response to calcium and alkaline-pH stress in Aspergillus nidulans . Molecular Microbiology 89:3, pages 532-551.
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Ruian Ke, Ken Haynes & Jaroslav Stark. (2013) Modelling the activation of alkaline pH response transcription factor PacC in Aspergillus nidulans: Involvement of a negative feedback loop. Journal of Theoretical Biology 326, pages 11-20.
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Teresa R. O'Meara & J. Andrew Alspaugh. (2012) The Cryptococcus neoformans Capsule: a Sword and a Shield. Clinical Microbiology Reviews 25:3, pages 387-408.
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Jawad Merhej, Florence Richard-Forget & Christian Barreau. (2011) The pH regulatory factor Pac1 regulates Tri gene expression and trichothecene production in Fusarium graminearum. Fungal Genetics and Biology 48:3, pages 275-284.
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Masafumi NishizawaMirai TanigawaMichio HayashiTatsuya MaedaYoshiaki Yazaki, Yasushi Saeki & Akio Toh-e. (2010) Pho85 Kinase, a Cyclin-Dependent Kinase, Regulates Nuclear Accumulation of the Rim101 Transcription Factor in the Stress Response of Saccharomyces cerevisiae. Eukaryotic Cell 9:6, pages 943-951.
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Shauna M. McKelvey & Richard A. Murphy. (2010) Analysis of wide-domain transcriptional regulation in solid-state cultures of Aspergillus oryzae. Journal of Industrial Microbiology & Biotechnology 37:5, pages 455-469.
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Teresa R. O'Meara, Diana Norton, Michael S. Price, Christie Hay, Meredith F. Clements, Connie B. Nichols & J. Andrew Alspaugh. (2010) Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule. PLoS Pathogens 6:2, pages e1000776.
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Joan Tilburn, Herbert N. ArstJr.Jr. & Miguel A. Peñalva. 2010. Cellular and Molecular Biology of Filamentous Fungi. Cellular and Molecular Biology of Filamentous Fungi 480 487 .
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Qin Wang & Paul J. Szaniszlo. (2009) Roles of the pH signaling transcription factor PacC in Wangiella (Exophiala) dermatitidis. Fungal Genetics and Biology 46:9, pages 657-666.
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Lidia Araújo-Bazán, Javier Fernández-Martínez, Vivian Maythe de los Ríos, Oier Etxebeste, Juan Pablo Albar, Miguel Ángel Peñalva & Eduardo Antonio Espeso. (2008) NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin α. Fungal Genetics and Biology 45:3, pages 278-291.
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Antonio Galindo, América Hervás-Aguilar, Olga Rodríguez-Galán, Olivier Vincent, Herbert N. ArstJrJr, Joan Tilburn & Miguel A. Peñalva. (2007) PalC, One of Two Bro1 Domain Proteins in the Fungal pH Signalling Pathway, Localizes to Cortical Structures and Binds Vps32. Traffic 8:10, pages 1346-1364.
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