64
Views
161
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Essential Role of Insulin Receptor Substrate 1 (IRS-1) and IRS-2 in Adipocyte Differentiation

, , , , , , , , , , , , , & show all
Pages 2521-2532 | Received 10 Jul 2000, Accepted 20 Dec 2000, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Gang Luo, Jialing Chen & Zhanjun Ren. (2021) Regulation of Methylase METTL3 on Fat Deposition. Diabetes, Metabolic Syndrome and Obesity 14, pages 4843-4852.
Read now
Aziz ur Rehman Aziz, Sumbal Farid, Kairong Qin, Hanqin Wang & Bo Liu. (2020) Regulation of insulin resistance and glucose metabolism by interaction of PIM kinases and insulin receptor substrates. Archives of Physiology and Biochemistry 126:2, pages 129-138.
Read now
Dexter Puckett, Mohammed Alquraishi, Dina S. Alani, Samah Chahed, Victoria D. Frankel, Dallas Donohoe, Brynn Voy, Jay Whelan & Ahmed Bettaieb. (2020) Zyflamend, a unique herbal blend, induces cell death and inhibits adipogenesis through the coordinated regulation of PKA and JNK. Adipocyte 9:1, pages 454-471.
Read now
Zhan-Qing Yang, Hong-Liang Zhang, Cui-Cui Duan, Shuang Geng, Kai Wang, Hai-Fan Yu, Zhan-Peng Yue & Bin Guo. (2017) IGF1 regulates RUNX1 expression via IRS1/2: Implications for antler chondrocyte differentiation. Cell Cycle 16:6, pages 522-532.
Read now
Chibueze A. Ihunnah, Taira Wada, Brian J. Philips, Sudheer K. Ravuri, Robert B. Gibbs, Levent Kirisci, J. Peter Rubin, Kacey G. Marra & Wen Xie. (2014) Estrogen Sulfotransferase/SULT1E1 Promotes Human Adipogenesis. Molecular and Cellular Biology 34:9, pages 1682-1694.
Read now
A. Cignarelli, F. Giorgino & R. Vettor. (2013) Pharmacologic agents for type 2 diabetes therapy and regulation of adipogenesis. Archives of Physiology and Biochemistry 119:4, pages 139-150.
Read now
Feng-Qian Li, Amar M. Singh, Adaobi Mofunanya, Damon Love, Naohiro Terada, Randall T. Moon & Ken-Ichi Takemaru. (2007) Chibby Promotes Adipocyte Differentiation through Inhibition of β-Catenin Signaling. Molecular and Cellular Biology 27:12, pages 4347-4354.
Read now
Marianna Sadagurski, Shoshana Yakar, Galina Weingarten, Martin Holzenberger, Christopher J. Rhodes, Dirk Breitkreutz, Derek LeRoith & Efrat Wertheimer. (2006) Insulin-Like Growth Factor 1 Receptor Signaling Regulates Skin Development and Inhibits Skin Keratinocyte Differentiation. Molecular and Cellular Biology 26:7, pages 2675-2687.
Read now
Yu-Hua Tseng, Kristina M. Kriauciunas, Efi Kokkotou & C. Ronald Kahn. (2004) Differential Roles of Insulin Receptor Substrates in Brown Adipocyte Differentiation. Molecular and Cellular Biology 24:5, pages 1918-1929.
Read now

Articles from other publishers (152)

Y. L. Wang, Y. H. Hou, Z. J. Ling, H. L. Zhao, X. R. Zheng, X. D. Zhang, Z. J. Yin & Y. Y. Ding. (2023) RNA sequencing analysis of the longissimus dorsi to identify candidate genes underlying the intramuscular fat content in Anqing Six‐end‐white pigs . Animal Genetics 54:3, pages 315-327.
Crossref
Liuying Zhu, Jinwu Zhang, Hui Yang, Guangyan Li, Hongyan Li, Zeyuan Deng & Bing Zhang. (2023) Propolis polyphenols: A review on the composition and anti-obesity mechanism of different types of propolis polyphenols. Frontiers in Nutrition 10.
Crossref
Hana Lee, Jin-Ho Lee, Doyong Kim, Donghyun Hwang, Minjoo Lee, Halim Chung, Tack-Joong Kim & Han Sung Kim. (2023) Micro-Current Stimulation Can Modulate the Adipogenesis Process by Regulating the Insulin Signaling Pathway in 3T3-L1 Cells and ob/ob Mice. Life 13:2, pages 404.
Crossref
Ruo-Han Hao, Yan Guo, Chen Wang, Fei Chen, Chen-Xi Di, Shan-Shan Dong, Qi-Long Cao, Jing Guo, Yu Rong, Shi Yao, Dong-Li Zhu, Yi-Xiao Chen, Hao Chen & Tie-Lin Yang. (2022) Lineage-specific rearrangement of chromatin loops and epigenomic features during adipocytes and osteoblasts commitment. Cell Death & Differentiation 29:12, pages 2503-2518.
Crossref
Xiaojun Ma, Yujie Guo, Jingjing Xu, Xixiang Wang, Shengqi Dong, Yanyan Gao, Nicholas Van Halm-Lutterodt & Linhong Yuan. (2022) Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice. Food Research International 162, pages 112207.
Crossref
Polina Lizunkova, Elin Engdahl, Gábor Borbély, Chris Gennings, Christian Lindh, Carl-Gustaf Bornehag & Joëlle Rüegg. (2022) A Mixture of Endocrine Disrupting Chemicals Associated with Lower Birth Weight in Children Induces Adipogenesis and DNA Methylation Changes in Human Mesenchymal Stem Cells. International Journal of Molecular Sciences 23:4, pages 2320.
Crossref
Jiaqi Zhao, Ailin Zhou & Wei Qi. (2022) The Potential to Fight Obesity with Adipogenesis Modulating Compounds. International Journal of Molecular Sciences 23:4, pages 2299.
Crossref
Seok-Hyeon Beak & Myunggi Baik. (2022) Comparison of transcriptome between high- and low-marbling fineness in longissimus thoracis muscle of Korean cattle. Animal Bioscience 35:2, pages 196-203.
Crossref
Hae-Lim Kim, Sung-Kwon Lee, Da-Eun Min, Bong-Keun Choi & Dong-Ryung Lee. (2022) Anti-Obesity Effects of a Mixture of Atractylodes macrocephala and Amomum villosum Extracts on 3T3-L1 Adipocytes and High-Fat Diet-Induced Obesity in Mice. Molecules 27:3, pages 906.
Crossref
Diya Sun, Zuoyou Ding, Lei Shen, Fan Yang, Jun Han & Guohao Wu. (2021) miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients. Lipids in Health and Disease 20:1.
Crossref
Katarzyna Kornicka-Garbowska, Lynda Bourebaba, Michael Röcken & Krzysztof Marycz. (2021) Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells. Cell Communication and Signaling 19:1.
Crossref
Dharmani Devi Murugan, Dharvind Balan & Pooi‐Fong Wong. (2021) Adipogenesis and therapeutic potentials of antiobesogenic phytochemicals: Insights from preclinical studies. Phytotherapy Research 35:11, pages 5936-5960.
Crossref
Ilona Rybinska, Nunzia Mangano, Elda Tagliabue & Tiziana Triulzi. (2021) Cancer-Associated Adipocytes in Breast Cancer: Causes and Consequences. International Journal of Molecular Sciences 22:7, pages 3775.
Crossref
Manal Al Dow, Maruhen Amir Datsch Silveira, Audrée Poliquin, Laura Tribouillard, Éric Fournier, Eva Trébaol, Blandine Secco, Romain Villot, Félix Tremblay, Steve Bilodeau & Mathieu Laplante. (2021) Control of adipogenic commitment by a STAT3-VSTM2A axis. American Journal of Physiology-Endocrinology and Metabolism 320:2, pages E259-E269.
Crossref
Zhen Jiang, Teng Feng, Zhengkai Lu, Yuanxin Wei, Jufeng Meng, Chao-Po Lin, Bin Zhou, Chen Liu & Hui Zhang. (2021) PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat. Cell Reports 34:5, pages 108697.
Crossref
Jian Zhang & Mahua Choudhury. (2021) Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line. Chemical Research in Toxicology 34:1, pages 54-62.
Crossref
Dae Hyun Kim, EunJin Bang, Sugyeong Ha, Hee Jin Jung, Yeon Ja Choi, Byung Pal Yu & Hae Young Chung. (2021) Organ-differential Roles of Akt/FoxOs Axis as a Key Metabolic Modulator during Aging. Aging and disease 12:7, pages 1713.
Crossref
Tanaporn Hengpratom, Gordon M. Lowe & Griangsak Eumkeb. (2020) An insight into anti-adipogenic properties of an Oroxylum indicum (L.) Kurz extract. BMC Complementary Medicine and Therapies 20:1.
Crossref
H.M. Jubayer Azam Bappy, Atoll Goswami, Nafiul Huda, Md Ismail Hosen & A.H.M. Nurun Nabi. (2020) Gender specific association of missense variant rs1805097 of IRS-2 and noncoding variant rs841853 of GLUT-1 genes with susceptibility to type 2 diabetes in Bangladeshi population. Gene Reports 21, pages 100866.
Crossref
Yan Qin Tan, Qing Li, Lin Wang, Leo C. Chiu-Leung & Lai K. Leung. (2020) The livestock growth-promoter zeranol facilitates GLUT4 translocation in 3T3 L1 adipocytes. Chemosphere 253, pages 126772.
Crossref
Li Wang, Song Zhang, Gong Cheng, Chugang Mei, Shijun Li, Wenzhen Zhang, Zainaguli Junjvlieke & Linsen Zan. (2020) MiR-145 reduces the activity of PI3K/Akt and MAPK signaling pathways and inhibits adipogenesis in bovine preadipocytes. Genomics 112:4, pages 2688-2694.
Crossref
Alexander Yang & Emilio P. Mottillo. (2020) Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics. Biochemical Journal 477:5, pages 985-1008.
Crossref
Zhifen ChenHaojie YuXu ShiCurtis R. WarrenLuca A. LottaMax FriesenTorsten B. MeissnerClaudia LangenbergMartin WabitschNick WarehamMark D. BensonRob E. GersztenChad A. Cowan. (2020) Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes. Circulation Research 126:3, pages 330-346.
Crossref
Heidi S. LumishMarcella O’ReillyMuredach P. Reilly. (2020) Sex Differences in Genomic Drivers of Adipose Distribution and Related Cardiometabolic Disorders. Arteriosclerosis, Thrombosis, and Vascular Biology 40:1, pages 45-60.
Crossref
Shajith Anoop & Nitin Kapoor. 2020. Obesity and Diabetes. Obesity and Diabetes 347 359 .
Yu-Hao Cheng, Jing-Cheng Dong & Qin Bian. (2019) Small molecules for mesenchymal stem cell fate determination. World Journal of Stem Cells 11:12, pages 1084-1103.
Crossref
Kitamura. (2019) Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models. Molecules 24:23, pages 4394.
Crossref
Xia Yi, Ping Wu, Jianyun Liu, Ying Gong, Xiaoyuan Xu & Weidong Li. (2019) Identification of the potential key genes for adipogenesis from human mesenchymal stem cells by RNA‐Seq. Journal of Cellular Physiology 234:11, pages 20217-20227.
Crossref
Sheng Zhou, Song Chen, Qing Jiang & Ming Pei. (2019) Determinants of stem cell lineage differentiation toward chondrogenesis versus adipogenesis. Cellular and Molecular Life Sciences 76:9, pages 1653-1680.
Crossref
Chihiro Matsumoto, Atsushi Koike, Reiko Tanaka & Ko Fujimori. (2019) A Limonoid, 7-Deacetoxy-7-Oxogedunin (CG-1) from Andiroba (Carapa guianensis, Meliaceae) Lowers the Accumulation of Intracellular Lipids in Adipocytes via Suppression of IRS-1/Akt-Mediated Glucose Uptake and a Decrease in GLUT4 Expression. Molecules 24:9, pages 1668.
Crossref
Junye Chen, Yi Lu, Mengyuan Tian & Qiren Huang. (2019) Molecular mechanisms of FOXO1 in adipocyte differentiation. Journal of Molecular Endocrinology 62:3, pages R239-R253.
Crossref
Thien Chu Dinh, Thuy Nguyen Thi Phuong, Le Bui Minh, Vu Thi Minh Thuc, Nguyen Duy Bac, Nguyen Van Tien, Van Huy Pham, Pau Loke Show, Yang Tao, Vo Truong Nhu Ngoc, Nguyen Thi Bich Ngoc, Adam Jurgoński, Deepak B. Thimiri Govinda Raj, Pham Van Tu, Vu Ngoc Ha, Joanna Czarzasta & Dinh-Toi Chu. (2019) The effects of green tea on lipid metabolism and its potential applications for obesity and related metabolic disorders - An existing update. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13:2, pages 1667-1673.
Crossref
Yangling Wang, Lei Yang, Xiaofeng Liu, Tao Hong, Tao Wang, Aiwu Dong, Jiangxiong Li, Xiaoyuan Xu & Lingling Cao. (2018) miR-431 inhibits adipogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting insulin receptor substance 2. Stem Cell Research & Therapy 9:1.
Crossref
R. J. F. Loos & T. O. Kilpeläinen. (2018) Genes that make you fat, but keep you healthy. Journal of Internal Medicine 284:5, pages 450-463.
Crossref
Tatiana Wojciechowicz, Jarosław Czubiński, Maria Billert, Artur Półciennik, Krzysztof W. Nowak & Marek Skrzypski. (2018) Suppressive effects of γ-conglutin on differentiation of 3T3-L1 preadipocytes. International Journal of Food Science & Technology 53:11, pages 2624-2630.
Crossref
Alexandre Pinel, Jean-Paul Rigaudière, Chrystèle Jouve & Frédéric Capel. (2018) Modulation of Insulin Resistance and the Adipocyte-Skeletal Muscle Cell Cross-Talk by LCn-3PUFA. International Journal of Molecular Sciences 19:9, pages 2778.
Crossref
Marie H. Solheim, Jonathon N. Winnay, Thiago M. Batista, Anders Molven, Pål R. Njølstad & C. Ronald Kahn. (2018) Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes. Diabetes 67:7, pages 1297-1309.
Crossref
Fumihiko Hakuno & Shin-Ichiro Takahashi. (2018) 40 YEARS OF IGF1: IGF1 receptor signaling pathways. Journal of Molecular Endocrinology 61:1, pages T69-T86.
Crossref
Atefeh Rabiee, Marcus Krüger, Jacob Ardenkjær-Larsen, C. Ronald Kahn & Brice Emanuelli. (2018) Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action. Cellular Signalling 47, pages 1-15.
Crossref
Gemma V. Brierley, Kenneth Siddle & Robert K. Semple. (2018) Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models. Diabetologia 61:7, pages 1662-1675.
Crossref
Jihoon Shin, Atsunori Fukuhara, Toshiharu Onodera, Shunbun Kita, Chieko Yokoyama, Michio Otsuki & Iichiro Shimomura. (2018) SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes 67:6, pages 1068-1078.
Crossref
Ruth JF Loos. (2018) The genetics of adiposity. Current Opinion in Genetics & Development 50, pages 86-95.
Crossref
Lam O. Huang, Ruth J. F. Loos & Tuomas O. Kilpeläinen. (2018) Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight. Physiological Genomics 50:3, pages 169-178.
Crossref
Patricia Sanmartín-Salinas, M. Val Toledo-Lobo, Fernando Noguerales-Fraguas, María-Encarnación Fernández-Contreras & Luis G. Guijarro. (2017) Overexpression of insulin receptor substrate-4 is correlated with clinical staging in colorectal cancer patients. Journal of Molecular Histology 49:1, pages 39-49.
Crossref
Wolfgang Link & Pablo J. Fernandez-Marcos. (2017) FOXO transcription factors at the interface of metabolism and cancer. International Journal of Cancer 141:12, pages 2379-2391.
Crossref
Angélica María Muñoz, Claudia María Velásquez, Gloria María Agudelo, Rosa Magdalena Uscátegui, Alejandro Estrada, Fredy Alonso Patiño, Beatriz Elena Parra, María Victoria Parra & Gabriel Bedoya. (2017) Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study. Genes & Nutrition 12:1.
Crossref
Kyoichiro Tsuchiya & Yoshihiro Ogawa. (2017) Forkhead box class O family member proteins: The biology and pathophysiological roles in diabetes. Journal of Diabetes Investigation 8:6, pages 726-734.
Crossref
Shifeng Pan, Yixin Cui, Xuan Dong, Tangjie Zhang & Hua Xing. (2017) MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression. Oncotarget 8:50, pages 87928-87943.
Crossref
Kerstin Rohde, Matthias Klös, Lydia Hopp, Xuanshi Liu, Maria Keller, Michael Stumvoll, Arne Dietrich, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dreßler, Peter Kovacs, Hans Binder, Matthias Blüher & Yvonne Böttcher. (2017) IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits. Scientific Reports 7:1.
Crossref
Mi‐Jeong Lee. 2011. Comprehensive Physiology. Comprehensive Physiology 1151 1195 .
Haiyin Han, Wei Wei, Weiwei Chu, Kaiqing Liu, Ye Tian, Zaohang Jiang & Jie Chen. (2017) Muscle Conditional Medium Reduces Intramuscular Adipocyte Differentiation and Lipid Accumulation through Regulating Insulin Signaling. International Journal of Molecular Sciences 18:8, pages 1799.
Crossref
Netta Nahum, Efrat Forti, Olga Aksanov & Ruth Birk. (2017) Insulin regulates Bbs4 during adipogenesis. IUBMB Life 69:7, pages 489-499.
Crossref
Ignazio Barbagallo, Giovanni Li Volti, Fabio Galvano, Guido Tettamanti, Francesca R Pluchinotta, Sonia Bergante & Luca Vanella. (2016) Diabetic human adipose tissue-derived mesenchymal stem cells fail to differentiate in functional adipocytes. Experimental Biology and Medicine 242:10, pages 1079-1085.
Crossref
Ji-Hyun Lee, Hyun Ah Jung, Min Jae Kang, Jae Sue Choi & Gun-Do Kim. (2017) Fucosterol, isolated from Ecklonia stolonifera , inhibits adipogenesis through modulation of FoxO1 pathway in 3T3-L1 adipocytes . Journal of Pharmacy and Pharmacology 69:3, pages 325-333.
Crossref
Huai-chih Chiang, Ya-Ting Kuo, Chih-Che Shen, Yi-Hua Lin, Shu-Li Wang & Tsui-Chun Tsou. (2014) Mono(2-ethylhexyl)phthalate accumulation disturbs energy metabolism of fat cells. Archives of Toxicology 90:3, pages 589-601.
Crossref
Matthijs P. Groeneveld, Gemma V. Brierley, Nuno M. Rocha, Kenneth Siddle & Robert K. Semple. (2016) Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production. Scientific Reports 6:1.
Crossref
Ching-Shu Lai, Ying-Yi Chen, Pei-Sheng Lee, Nagabhushanam Kalyanam, Chi-Tang Ho, Wen-Shiung Liou, Roch-Chui Yu & Min-Hsiung Pan. (2016) Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. Journal of Agricultural and Food Chemistry 64:4, pages 821-830.
Crossref
Peng Zhou, Maricela Robles-Murguia, Deepa Mathew & Giles E. Duffield. (2016) Impaired Thermogenesis and a Molecular Signature for Brown Adipose Tissue in Id2 Null Mice . Journal of Diabetes Research 2016, pages 1-11.
Crossref
Eugenio J. Abente, Murugan Subramanian, Vimal Ramachandran & S. Hani Najafi-Shoushtari. (2016) MicroRNAs in obesity-associated disorders. Archives of Biochemistry and Biophysics 589, pages 108-119.
Crossref
Ying-Ju Chang, Scott Pownall, Thomas E Jensen, Samar Mouaaz, Warren Foltz, Lily Zhou, Nicole Liadis, Minna Woo, Zhenyue Hao, Previn Dutt, Philip J Bilan, Amira Klip, Tak Mak & Vuk Stambolic. (2015) The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes. eLife 4.
Crossref
Yukinori Tamura, Naoyuki Kawao, Masato Yano, Kiyotaka Okada, Katsumi Okumoto, Yasutaka Chiba, Osamu Matsuo & Hiroshi Kaji. (2015) Role of Plasminogen Activator Inhibitor-1 in Glucocorticoid-Induced Diabetes and Osteopenia in Mice. Diabetes 64:6, pages 2194-2206.
Crossref
Alexander Dmitrievich Egorov, Dmitry Nikolaevich Penkov & Vsevolod Arsen'evich Tkachuk. (2015) Molecular and cellular mechanisms of adipogenesis. Diabetes mellitus 18:2, pages 12-19.
Crossref
Peter Lanzerstorfer, Yosuke Yoneyama, Fumihiko Hakuno, Ulrike Müller, Otmar Höglinger, Shin‐Ichiro Takahashi & Julian Weghuber. (2015) Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces. The FEBS Journal 282:6, pages 987-1005.
Crossref
Ilaria Caldarelli, Maria Carmela Speranza, Debora Bencivenga, Annunziata Tramontano, Alessia Borgia, Anna Virginia Adriana Pirozzi, Silverio Perrotta, Adriana Oliva, Fulvio Della Ragione & Adriana Borriello. (2015) Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells. The International Journal of Biochemistry & Cell Biology 60, pages 60-72.
Crossref
Alan R. Saltiel. 2016. Metabolic Control. Metabolic Control 51 71 .
Mohamad Bakar, Mohamad Sarmidi, Cheng Kai, Hasniza Huri & Harisun Yaakob. (2014) Amelioration of Mitochondrial Dysfunction-Induced Insulin Resistance in Differentiated 3T3-L1 Adipocytes via Inhibition of NF-κB Pathways. International Journal of Molecular Sciences 15:12, pages 22227-22257.
Crossref
Yu Li, Guohong Qin, Jun Liu, Lifei Mao, Zhichao Zhang & Jing Shang. (2014) Adipose tissue regulates hepatic cholesterol metabolism via adiponectin. Life Sciences 118:1, pages 27-33.
Crossref
Shannon Liu, Ruichuan Xu, Isabelle Gerin, William P. Cawthorn, Ormond A. MacDougald, Xiao-Wei Chen, Alan R. Saltiel, Ronald J. Koenig & Bin Xu. (2014) SRA Regulates Adipogenesis by Modulating p38/JNK Phosphorylation and Stimulating Insulin Receptor Gene Expression and Downstream Signaling. PLoS ONE 9:4, pages e95416.
Crossref
N. Boulet, D. Estève, A. Bouloumié & J. Galitzky. (2013) L’adipogenèse des tissus adipeux blancs : influence du microenvironnementAdipogenesis in white adipose tissues: influence of the microenvironment. Obésité 9:1, pages 42-55.
Crossref
Young-Je Kim, Myung-Sook Choi, Byung Yoon Cha, Je Tae Woo, Yong Bok Park, Sang Ryong Kim & Un Ju Jung. (2013) Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice. Molecular Nutrition & Food Research 57:11, pages 1988-1998.
Crossref
Kishan Kumar Chudasama, Jonathon Winnay, Stefan Johansson, Tor Claudi, Rainer König, Ingfrid Haldorsen, Bente Johansson, Ju Rang Woo, Dagfinn Aarskog, Jørn V. Sagen, C. Ronald Kahn, Anders Molven & Pål Rasmus Njølstad. (2013) SHORT Syndrome with Partial Lipodystrophy Due to Impaired Phosphatidylinositol 3 Kinase Signaling. The American Journal of Human Genetics 93:1, pages 150-157.
Crossref
S Y Min, H Yang, S G Seo, S H Shin, M-Y Chung, J Kim, S J Lee, H J Lee & K W Lee. (2012) Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor. International Journal of Obesity 37:4, pages 584-592.
Crossref
Hannah B. Richards & Mark I. McCarthy. (2012) Recent Developments in the Genetic and Genomic Basis of Type 2 Diabetes. Current Cardiovascular Risk Reports 7:1, pages 66-72.
Crossref
D. N. Penkov, A. D. Egorov, M. N. Mozgovaya & V. A. Tkachuk. (2013) Insulin resistance and adipogenesis: Role of transcription and secreted factors. Biochemistry (Moscow) 78:1, pages 8-18.
Crossref
M. Skrzypski, P. Kaczmarek, T.T. Le, T. Wojciechowicz, E. Pruszyńska-Oszmalek, D. Szczepankiewicz, M. Sassek, A. Arafat, B. Wiedenmann, K.W. Nowak & M.Z. Strowski. (2012) Effects of orexin A on proliferation, survival, apoptosis and differentiation of 3T3-L1 preadipocytes into mature adipocytes. FEBS Letters 586:23, pages 4157-4164.
Crossref
K. D. Copps & M. F. White. (2012) Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 55:10, pages 2565-2582.
Crossref
Siegfried Ussar, Olivier Bezy, Matthias Blüher & C. Ronald Kahn. (2012) Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine. Diabetes 61:9, pages 2289-2298.
Crossref
Shalini Ojha, Helen Budge & Michael E. Symonds. 2012. Maternal Obesity. Maternal Obesity 124 134 .
Stephen Fitter, Kate Vandyke, Stan Gronthos & Andrew C W Zannettino. (2012) Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion. Journal of Molecular Endocrinology 48:3, pages 229-240.
Crossref
Balu Venugopal, Francis B. Fernandez, Suresh S. Babu, V. S. Harikrishnan, Harikrishna Varma & Annie John. (2012) Adipogenesis on biphasic calcium phosphate using rat adipose-derived mesenchymal stem cells: In vitro and in vivo. Journal of Biomedical Materials Research Part A 100A:6, pages 1427-1437.
Crossref
Qin HaoHaldis H. Lillefosse, Even Fjære, Lene Secher Myrmel, Lisa K. Midtbø, Ragnhild H. Jarlsby, Tao MaBingbing JiaRasmus K. PetersenSi B. SonneAndré Chwalibog, Livar Frøyland, Bjørn Liaset, Karsten KristiansenLise Madsen. (2012) High-glycemic index carbohydrates abrogate the antiobesity effect of fish oil in mice. American Journal of Physiology-Endocrinology and Metabolism 302:9, pages E1097-E1112.
Crossref
Takafumi Uchida, Kengo Furumai, Tomokazu Fukuda, Hirotada Akiyama, Mika Takezawa, Tomoichiro Asano, Fumihiro Fujimori & Chiyoko Uchida. (2012) Prolyl Isomerase Pin1 Regulates Mouse Embryonic Fibroblast Differentiation into Adipose Cells. PLoS ONE 7:3, pages e31823.
Crossref
Lei Yang, Xiao-Fan Li, Lei Gao, Ya-Ou Zhang & Guo-Ping Cai. (2012) Suppressive Effects of Quercetin-3- O -(6″-Feruloyl)-β-D-Galactopyranoside on Adipogenesis in 3T3-L1 Preadipocytes Through Down-regulation of PPARγ and C/EBPα Expression . Phytotherapy Research 26:3, pages 438-444.
Crossref
Gun-Pyo Do, Hye-Jin Lee, Jeong-Ryong Do & Hyun-Ku Kim. (2012) Antiobesity Effect of the Cucubita moschata Duch Extracts in 3T3-L1 Adipocyets. Korean Journal of Food Preservation 19:1, pages 138-143.
Crossref
Stavroula Kousteni. (2012) FoxO1, the transcriptional chief of staff of energy metabolism. Bone 50:2, pages 437-443.
Crossref
Tuomas O Kilpeläinen, M Carola Zillikens, Alena Stančákova, Francis M Finucane, Janina S Ried, Claudia Langenberg, Weihua Zhang, Jacques S Beckmann, Jian'an Luan, Liesbeth Vandenput, Unnur Styrkarsdottir, Yanhua Zhou, Albert Vernon Smith, Jing-Hua Zhao, Najaf Amin, Sailaja Vedantam, So-Youn Shin, Talin Haritunians, Mao Fu, Mary F Feitosa, Meena Kumari, Bjarni V Halldorsson, Emmi Tikkanen, Massimo Mangino, Caroline Hayward, Ci Song, Alice M Arnold, Yurii S Aulchenko, Ben A Oostra, Harry Campbell, L Adrienne Cupples, Kathryn E Davis, Angela Döring, Gudny Eiriksdottir, Karol Estrada, José Manuel Fernández-Real, Melissa Garcia, Christian Gieger, Nicole L Glazer, Candace Guiducci, Albert Hofman, Steve E Humphries, Bo Isomaa, Leonie C Jacobs, Antti Jula, David Karasik, Magnus K Karlsson, Kay-Tee Khaw, Lauren J Kim, Mika Kivimäki, Norman Klopp, Brigitte Kühnel, Johanna Kuusisto, Yongmei Liu, Östen Ljunggren, Mattias Lorentzon, Robert N Luben, Barbara McKnight, Dan Mellström, Braxton D Mitchell, Vincent Mooser, José Maria Moreno, Satu Männistö, Jeffery R O'Connell, Laura Pascoe, Leena Peltonen, Belén Peral, Markus Perola, Bruce M Psaty, Veikko Salomaa, David B Savage, Robert K Semple, Tatjana Skaric-Juric, Gunnar Sigurdsson, Kijoung S Song, Timothy D Spector, Ann-Christine Syvänen, Philippa J Talmud, Gudmar Thorleifsson, Unnur Thorsteinsdottir, André G Uitterlinden, Cornelia M van Duijn, Antonio Vidal-Puig, Sarah H Wild, Alan F Wright, Deborah J Clegg, Eric Schadt, James F Wilson, Igor Rudan, Samuli Ripatti, Ingrid B Borecki, Alan R Shuldiner, Erik Ingelsson, John-Olov Jansson, Robert C Kaplan, Vilmundur Gudnason, Tamara B Harris, Leif Groop, Douglas P Kiel, Fernando Rivadeneira, Mark Walker, Inês Barroso, Peter Vollenweider, Gérard Waeber, John C Chambers, Jaspal S Kooner, Nicole Soranzo, Joel N Hirschhorn, Kari Stefansson, H-Erich Wichmann, Claes Ohlsson, Stephen O'Rahilly, Nicholas J Wareham, Elizabeth K Speliotes, Caroline S Fox, Markku Laakso & Ruth J F Loos. (2011) Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics 43:8, pages 753-760.
Crossref
Su-Jin Kim, Cuilan Nian & Christopher H.S. McIntosh. (2011) Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation. Journal of Lipid Research 52:4, pages 759-770.
Crossref
Ognian C. Ikonomov, Diego Sbrissa, Khortnal Delvecchio, Yufen Xie, Jian-Ping Jin, Daniel Rappolee & Assia Shisheva. (2011) The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development. Journal of Biological Chemistry 286:15, pages 13404-13413.
Crossref
Sachiko Juman, Naomi Yasui, Hiroto Okuda, Ai Ueda, Hiroko Negishi, Tomohiro Miki & Katsumi Ikeda. (2011) Caffeic Acid Phenethyl Ester Suppresses the Production of Adipocytokines, Leptin, Tumor Necrosis Factor -Alpha and Resistin, during Differentiation to Adipocytes in 3T3-L1 Cells. Biological and Pharmaceutical Bulletin 34:4, pages 490-494.
Crossref
Cullen M. Taniguchi & C. Ronald Kahn. 2011. Insulin Resistance and Cancer. Insulin Resistance and Cancer 53 76 .
Masanobu Kawai & Clifford J. Rosen. (2010) The IGF-I regulatory system and its impact on skeletal and energy homeostasis. Journal of Cellular Biochemistry 111:1, pages 14-19.
Crossref
Kelly Cleveland-DonovanLaura A. MaileWilliam G. TsiarasTamara Tchkonia, James L. Kirkland & Charlotte M. Boney. (2010) IGF-I Activation of the AKT Pathway Is Impaired in Visceral But Not Subcutaneous Preadipocytes from Obese Subjects. Endocrinology 151:8, pages 3752-3763.
Crossref
Roselle L. Cripps & Susan E. Ozanne. 2010. Adipose Tissue in Health and Disease. Adipose Tissue in Health and Disease 459 472 .
Lise Madsen & Karsten Kristiansen. (2010) The importance of dietary modulation of cAMP and insulin signaling in adipose tissue and the development of obesity. Annals of the New York Academy of Sciences 1190:1, pages 1-14.
Crossref
Anna Meiliana & Andi Wijaya. (2009) Adipose Tissue Biology: An Update Review. The Indonesian Biomedical Journal 1:3, pages 4.
Crossref
Keisuke Munekata & Kazuichi Sakamoto. (2009) Forkhead transcription factor Foxo1 is essential for adipocyte differentiation. In Vitro Cellular & Developmental Biology - Animal 45:10, pages 642-651.
Crossref
Frédéric BouchardJoanne Paquin. (2009) Skeletal and Cardiac Myogenesis Accompany Adipogenesis in P19 Embryonal Stem Cells. Stem Cells and Development 18:7, pages 1023-1032.
Crossref
Toyonobu Maeda & Noboru Horiuchi. (2009) Simvastatin Suppresses Leptin Expression in 3T3-L1 Adipocytes via Activation of the Cyclic AMP–PKA Pathway Induced by Inhibition of Protein Prenylation. The Journal of Biochemistry 145:6, pages 771-781.
Crossref
Anja Böhm, Harald Staiger, Anita M. Hennige, Carina Haas, Fausto Machicao & Hans-Ulrich Häring. (2008) Effect of insulin detemir, compared to human insulin, on 3T3-L1 adipogenesis. Regulatory Peptides 151:1-3, pages 160-163.
Crossref
S. A. Bayol, B. H. Simbi, J. A. Bertrand & N. C. Stickland. (2008) Offspring from mothers fed a ‘junk food’ diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females. The Journal of Physiology 586:13, pages 3219-3230.
Crossref
Rebeca Garcia-Macedo, Fausto Sanchez-Muñoz, Julio Cesar Almanza-Perez, Genoveva Duran-Reyes, Francisco Alarcon-Aguilar & Miguel Cruz. (2008) Glycine increases mRNA adiponectin and diminishes pro-inflammatory adipokines expression in 3T3-L1 cells. European Journal of Pharmacology 587:1-3, pages 317-321.
Crossref
D N Gross, A P J van den Heuvel & M J Birnbaum. (2008) The role of FoxO in the regulation of metabolism. Oncogene 27:16, pages 2320-2336.
Crossref
Say Viengchareun, Nathalie Servel, Bruno Fève, Michael Freemark, Marc Lombès & Nadine Binart. (2008) Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2. PLoS ONE 3:2, pages e1535.
Crossref
Fuqiang Li, Dongmei Wang, Yiran Zhou, Bo Zhou, Yanan Yang, Hehua Chen & Jianguo Song. (2008) Protein kinase A suppresses the differentiation of 3T3-L1 preadipocytes. Cell Research 18:2, pages 311-323.
Crossref
Jun Nakae, Miyo Oki & Yongheng Cao. (2008) The FoxO transcription factors and metabolic regulation. FEBS Letters 582:1, pages 54-67.
Crossref
Christian X. Andersson, Ann Hammarstedt, Per-Anders Jansson & Ulf Smith. 2008. The Metabolic Syndrome. The Metabolic Syndrome 189 204 .
Yusuke Murata, Kaku Tsuruzoe, Junji Kawashima, Noboru Furukawa, Tatsuya Kondo, Hiroyuki Motoshima, Motoyuki Igata, Kayo Taketa, Kazunari Sasaki, Hideki Kishikawa, C. Ronald Kahn, Tetsushi Toyonaga & Eiichi Araki. (2007) IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance. Biochemical and Biophysical Research Communications 364:2, pages 301-307.
Crossref
Marianna Sadagurski, Sharon Nofech-Mozes, Galina Weingarten, Morris F. White, Takashi Kadowaki & Efrat Wertheimer. (2007) Insulin receptor substrate 1 (IRS-1) plays a unique role in normal epidermal physiology. Journal of Cellular Physiology 213:2, pages 519-527.
Crossref
Michio Noguchi, Kiminori Hosoda, Junji Fujikura, Muneya Fujimoto, Hiroshi Iwakura, Tsutomu Tomita, Takako Ishii, Naoki Arai, Masakazu Hirata, Ken Ebihara, Hiroaki Masuzaki, Hiroshi Itoh, Shuh Narumiya & Kazuwa Nakao. (2007) Genetic and Pharmacological Inhibition of Rho-associated Kinase II Enhances Adipogenesis. Journal of Biological Chemistry 282:40, pages 29574-29583.
Crossref
Takahiro Naiki, Eiko Saijou, Yuichiro Miyaoka, Keisuke Sekine & Atsushi Miyajima. (2007) TRB2, a Mouse Tribbles Ortholog, Suppresses Adipocyte Differentiation by Inhibiting AKT and C/EBPβ. Journal of Biological Chemistry 282:33, pages 24075-24082.
Crossref
Jane J. Kim, Yoshiaki Kido, Philipp E. Scherer, Morris F. White & Domenico Accili. (2007) Analysis of compensatory β-cell response in mice with combined mutations of Insr and Irs2 . American Journal of Physiology-Endocrinology and Metabolism 292:6, pages E1694-E1701.
Crossref
Mathew M. Avram, Alison Sharpe Avram & William D. James. (2007) Subcutaneous fat in normal and diseased states. Journal of the American Academy of Dermatology 56:3, pages 472-492.
Crossref
Susanna Freude & Markus Schubert. (2007) Insulin resistance: Mutagenesis of the insulin receptor and its substrates in mice. Drug Discovery Today: Disease Models 4:1, pages 9-16.
Crossref
Dhananjay Gupta, Shailly Varma & Ramji L. Khandelwal. (2007) Long-term effects of tumor necrosis factor-α treatment on insulin signaling pathway in HepG2 cells and HepG2 cells overexpressing constitutively active Akt/PKB. Journal of Cellular Biochemistry 100:3, pages 593-607.
Crossref
Hua Zhou, Xi Yang, Nai-li Wang, Ya-ou Zhang & Guo-ping Cai. (2007) Macrostemonoside A Promotes Visfatin Expression in 3T3-L1 Cells. Biological and Pharmaceutical Bulletin 30:2, pages 279-283.
Crossref
Francesco Oriente & Domenico Accili. 2007. Mechanisms of Insulin Action. Mechanisms of Insulin Action 168 184 .
Jean J. Zhao, Hailing Cheng, Shidong Jia, Li Wang, Ole V. Gjoerup, Aki Mikami & Thomas M. Roberts. (2006) The p110α isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation. Proceedings of the National Academy of Sciences 103:44, pages 16296-16300.
Crossref
Morichika Konishi, Toshiyuki Asaki, Naomi Koike, Hiroyuki Miwa, Ayumi Miyake & Nobuyuki Itoh. (2006) Role of Fgf10 in cell proliferation in white adipose tissue. Molecular and Cellular Endocrinology 249:1-2, pages 71-77.
Crossref
Anne Baudry, Zhong-Zhou Yang & Brian A. Hemmings. (2006) PKBα is required for adipose differentiation of mouse embryonic fibroblasts. Journal of Cell Science 119:5, pages 889-897.
Crossref
Jeff HollyMatt SabinClaire PerksJulian Shield. (2006) Adipogenesis and IGF-1. Metabolic Syndrome and Related Disorders 4:1, pages 43-50.
Crossref
Cullen M. Taniguchi, Brice Emanuelli & C. Ronald Kahn. (2006) Critical nodes in signalling pathways: insights into insulin action. Nature Reviews Molecular Cell Biology 7:2, pages 85-96.
Crossref
. (2005) Effect of Cinnamomum camphora Leaf Fractions on Insulin Action. Journal of the Korean Society of Food Science and Nutrition 34:9, pages 1336-1343.
Crossref
Alexander S. Banks, Jianze Li, Lisa McKeag, Marta L. Hribal, Masaki Kashiwada, Domenico Accili & Paul B. Rothman. (2005) Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. Journal of Clinical Investigation 115:9, pages 2462-2471.
Crossref
Hiroaki Kimura, Miho Kimura, William H. Westra, Noel R. Rose & Patrizio Caturegli. (2005) Increased thyroidal fat and goitrous hypothyroidism induced by interferon-γ. International Journal of Experimental Pathology 86:2, pages 97-106.
Crossref
Ryo Suzuki, Kazuyuki Tobe, Masashi Aoyama, Kentaro Sakamoto, Mitsuru Ohsugi, Nozomu Kamei, Shigeyuki Nemoto, Atsushi Inoue, Yusuke Ito, Shoko Uchida, Kazuo Hara, Toshimasa Yamauchi, Naoto Kubota, Yasuo Terauchi & Takashi Kadowaki. (2005) Expression of DGAT2 in White Adipose Tissue Is Regulated by Central Leptin Action. Journal of Biological Chemistry 280:5, pages 3331-3337.
Crossref
A. M. Valverde, M. Benito & M. Lorenzo. (2005) The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance. Acta Physiologica Scandinavica 183:1, pages 59-73.
Crossref
Sachiko Tominaga, Tomohiro Yamaguchi, Shin-Ichiro Takahashi, Fumiko Hirose & Takashi Osumi. (2005) Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase. Biochemical and Biophysical Research Communications 326:2, pages 499-504.
Crossref
Junji Kamon, Toshimasa Yamauchi, Susumu Muto, Sato Takekawa, Yusuke Ito, Yusuke Hada, Wataru Ogawa, Akiko Itai, Masato Kasuga, Kazuyuki Tobe & Takashi Kadowaki. (2004) A novel IKKβ inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance. Biochemical and Biophysical Research Communications 323:1, pages 242-248.
Crossref
. (2004) Hypoglycemic Effects of Crude Extracts of Prunus mume. Journal of the Korean Society of Food Science and Nutrition 33:6, pages 951-957.
Crossref
Hyuntae Yoo, Gregory Stephanopoulos & Joanne K. Kelleher. (2004) Quantifying carbon sources for de novo lipogenesis in wild-type and IRS-1 knockout brown adipocytes. Journal of Lipid Research 45:7, pages 1324-1332.
Crossref
Jack Phan, Miklós Péterfy & Karen Reue. (2004) Lipin Expression Preceding Peroxisome Proliferator-activated Receptor-γ Is Critical for Adipogenesis in Vivo and in Vitro. Journal of Biological Chemistry 279:28, pages 29558-29564.
Crossref
ANINDITA NANDI, YUKARI KITAMURA, C. RONALD KAHN & DOMENICO ACCILI. (2004) Mouse Models of Insulin Resistance. Physiological Reviews 84:2, pages 623-647.
Crossref
Toshiyasu Sasaoka, Tsutomu Wada, Kazuhito Fukui, Shihou Murakami, Hajime Ishihara, Ryo Suzuki, Kazuyuki Tobe, Takashi Kadowaki & Masashi Kobayashi. (2004) SH2-containing Inositol Phosphatase 2 Predominantly Regulates Akt2, and Not Akt1, Phosphorylation at the Plasma Membrane in Response to Insulin in 3T3-L1 Adipocytes. Journal of Biological Chemistry 279:15, pages 14835-14843.
Crossref
D El-Chaâr, A Gagnon & A Sorisky. (2004) Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1. International Journal of Obesity 28:2, pages 191-198.
Crossref
Hiroshi Sakaue, Akihiko Nishizawa, Wataru Ogawa, Kiyoshi Teshigawara, Toshiyuki Mori, Yasuhiro Takashima, Tetsuo Noda & Masato Kasuga. (2003) Requirement for 3-Phosphoinositide-dependent Kinase-1 (PDK-1) in Insulin-induced Glucose Uptake in Immortalized Brown Adipocytes. Journal of Biological Chemistry 278:40, pages 38870-38874.
Crossref
Hironori Waki, Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, Shoko Uchida, Shunbun Kita, Kazuo Hara, Yusuke Hada, Francis Vasseur, Philippe Froguel, Satoshi Kimura, Ryozo Nagai & Takashi Kadowaki. (2003) Impaired Multimerization of Human Adiponectin Mutants Associated with Diabetes. Journal of Biological Chemistry 278:41, pages 40352-40363.
Crossref
Norbert Stefan, Peter Kovacs, Michael Stumvoll, Robert L. Hanson, Angela Lehn-Stefan, Paska A. Permana, Leslie J. Baier, P. Antonio Tataranni, Kristi Silver & Clifton Bogardus. (2003) Metabolic Effects of the Gly1057Asp Polymorphism in IRS-2 and Interactions With Obesity . Diabetes 52:6, pages 1544-1550.
Crossref
Hiroko Sekimoto & Charlotte M. Boney. (2003) C-Terminal Src Kinase (CSK) Modulates Insulin-Like Growth Factor-I Signaling through Src in 3T3-L1 Differentiation. Endocrinology 144:6, pages 2546-2552.
Crossref
Xiao-ding Peng, Pei-Zhang Xu, Mei-Ling Chen, Annett Hahn-Windgassen, Jennifer Skeen, Joel Jacobs, Deepa Sundararajan, William S. Chen, Susan E. Crawford, Kevin G. Coleman & Nissim Hay. (2003) Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes & Development 17:11, pages 1352-1365.
Crossref
Raffaella Sordella, Wei Jiang, Guang-Chao Chen, Marcello Curto & Jeffrey Settleman. (2003) Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis. Cell 113:2, pages 147-158.
Crossref
Angela M. Valverde, Mónica Arribas, Cecilia Mur, Paloma Navarro, Sebastián Pons, Anne-Marie Cassard-Doulcier, C. Ronald Kahn & Manuel Benito. (2003) Insulin-induced Up-regulated Uncoupling Protein-1 Expression Is Mediated by Insulin Receptor Substrate 1 through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Fetal Brown Adipocytes. Journal of Biological Chemistry 278:12, pages 10221-10231.
Crossref
Cecilia Mur, Mónica Arribas, Manuel Benito & Angela M. Valverde. (2003) Essential Role of Insulin-Like Growth Factor I Receptor in Insulin-Induced Fetal Brown Adipocyte Differentiation. Endocrinology 144:2, pages 581-593.
Crossref
Jun Nakae, Tadahiro Kitamura, Yukari Kitamura, William H. BiggsIIIIII, Karen C. Arden & Domenico Accili. (2003) The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation. Developmental Cell 4:1, pages 119-129.
Crossref
Masaki Watanabe, Kouichi Inukai, Hideki Katagiri, Takuya Awata, Yoshitomo Oka & Shigehiro Katayama. (2003) Regulation of PPARγ transcriptional activity in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications 300:2, pages 429-436.
Crossref
Alexander Sorisky, Annemarie Gagnon, Andrea Bell & Darine El-Chaar. 2003. Atherosclerosis, Hypertension and Diabetes. Atherosclerosis, Hypertension and Diabetes 119 127 .
Ognian C. Ikonomov, Diego Sbrissa, Krzysztof Mlak & Assia Shisheva. (2002) Requirement for PIKfyve Enzymatic Activity in Acute and Long-Term Insulin Cellular Effects. Endocrinology 143:12, pages 4742-4754.
Crossref
U Smith. (2002) Impaired (‘diabetic’) insulin signaling and action occur in fat cells long before glucose intolerance—is insulin resistance initiated in the adipose tissue?. International Journal of Obesity 26:7, pages 897-904.
Crossref
Michihiro Matsumoto, Wataru Ogawa, Kiyoshi Teshigawara, Hiroshi Inoue, Kazuaki Miyake, Hiroshi Sakaue & Masato Kasuga. (2002) Role of the Insulin Receptor Substrate 1 and Phosphatidylinositol 3-Kinase Signaling Pathway in Insulin-Induced Expression of Sterol Regulatory Element Binding Protein 1c and Glucokinase Genes in Rat Hepatocytes. Diabetes 51:6, pages 1672-1680.
Crossref
Philippe Valet, Genevieéve Tavernier, Isabelle Castan-Laurell, Jean Sébastien Saulnier-Blache & Dominique Langin. (2002) Understanding adipose tissue development from transgenic animal models. Journal of Lipid Research 43:6, pages 835-860.
Crossref
Hiroshi Sakaue, Morichika Konishi, Wataru Ogawa, Toshiyuki Asaki, Toshiyuki Mori, Masahiro Yamasaki, Masafumi Takata, Hikaru Ueno, Shigeaki Kato, Masato Kasuga & Nobuyuki Itoh. (2002) Requirement of fibroblast growth factor 10 in development of white adipose tissue. Genes & Development 16:8, pages 908-912.
Crossref
Jheem D. Medh. (2002) Genetics and molecular biology: a role for adipocyte lipid-binding protein in atherosclerosis. Current Opinion in Lipidology 13:1, pages 93-95.
Crossref
Ormond A MacDougald & Susanne Mandrup. (2002) Adipogenesis: forces that tip the scales. Trends in Endocrinology & Metabolism 13:1, pages 5-11.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.