Advanced search
Publication Cover
Molecular and Cellular Biology Volume 21, 2001 - Issue 8
Submit an article Journal homepage
24
Views
160
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Histone Acetylation at Promoters Is Differentially Affected by Specific Activators and Repressors

Jutta DeckertDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, 02115
&
Kevin StruhlDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, 02115Correspondence[email protected]
Pages 2726-2735 | Received 28 Nov 2000, Accepted 22 Jan 2001, Published online: 28 Mar 2023

Citations (160)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (18)

Alec M. DeSimone & Jeffrey D. Laney. (2010) Corepressor-Directed Preacetylation of Histone H3 in Promoter Chromatin Primes Rapid Transcriptional Switching of Cell-Type-Specific Genes in Yeast. Molecular and Cellular Biology 30:13, pages 3342-3356.
Read now
Sushma Shivaswamy & Vishwanath R. Iyer. (2008) Stress-Dependent Dynamics of Global Chromatin Remodeling in Yeast: Dual Role for SWI/SNF in the Heat Shock Stress Response. Molecular and Cellular Biology 28:7, pages 2221-2234.
Read now
Marc A. Schwabish & Kevin Struhl. (2007) The Swi/Snf Complex Is Important for Histone Eviction during Transcriptional Activation and RNA Polymerase II Elongation In Vivo. Molecular and Cellular Biology 27:20, pages 6987-6995.
Read now
T. Y. Erkina & A. M. Erkine. (2006) Displacement of Histones at Promoters of Saccharomyces cerevisiae Heat Shock Genes Is Differentially Associated with Histone H3 Acetylation. Molecular and Cellular Biology 26:20, pages 7587-7600.
Read now
Rachel Maria Imoberdorf, Irini Topalidou & Michel Strubin. (2006) A Role for Gcn5-Mediated Global Histone Acetylation in Transcriptional Regulation. Molecular and Cellular Biology 26:5, pages 1610-1616.
Read now
Maryam Fouladi. (2006) Histone Deacetylase Inhibitors in Cancer Therapy. Cancer Investigation 24:5, pages 521-527.
Read now
Soon-ja Kim, Mark J. Swanson, Hongfang Qiu, Chhabi K. Govind & Alan G. Hinnebusch. (2005) Activator Gcn4p and Cyc8p/Tup1p Are Interdependent for Promoter Occupancy at ARG1 In Vivo. Molecular and Cellular Biology 25:24, pages 11171-11183.
Read now
Jing Zhao, Jorge Herrera-Diaz & David S. Gross. (2005) Domain-Wide Displacement of Histones by Activated Heat Shock Factor Occurs Independently of Swi/Snf and Is Not Correlated with RNA Polymerase II Density. Molecular and Cellular Biology 25:20, pages 8985-8999.
Read now
Rhea T. Utley, Nicolas Lacoste, Olivier Jobin-Robitaille, Stéphane Allard & Jacques Côté. (2005) Regulation of NuA4 Histone Acetyltransferase Activity in Transcription and DNA Repair by Phosphorylation of Histone H4. Molecular and Cellular Biology 25:18, pages 8179-8190.
Read now
Egle Balciunaite, Alexander Spektor, Nathan H. Lents, Hugh Cam, Hein te Riele, Anthony Scime, Michael A. Rudnicki, Richard Young & Brian David Dynlacht. (2005) Pocket Protein Complexes Are Recruited to Distinct Targets in Quiescent and Proliferating Cells. Molecular and Cellular Biology 25:18, pages 8166-8178.
Read now
Philip J Nivatpumin & Steven D Gore. (2005) Emerging drugs for the treatment of myelodysplastic syndrome. Expert Opinion on Emerging Drugs 10:3, pages 569-590.
Read now
Meghana M. Kulkarni & David N. Arnosti. (2005) cis-Regulatory Logic of Short-Range Transcriptional Repression in Drosophila melanogaster. Molecular and Cellular Biology 25:9, pages 3411-3420.
Read now
Marc A. Schwabish & Kevin Struhl. (2004) Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II. Molecular and Cellular Biology 24:23, pages 10111-10117.
Read now
Irini Topalidou, Manolis Papamichos-Chronakis & George Thireos. (2003) Post-TATA Binding Protein Recruitment Clearance of Gcn5-Dependent Histone Acetylation within Promoter Nucleosomes. Molecular and Cellular Biology 23:21, pages 7809-7817.
Read now
Anne Rascle, James A. Johnston & Bruno Amati. (2003) Deacetylase Activity Is Required for Recruitment of the Basal Transcription Machinery and Transactivation by STAT5. Molecular and Cellular Biology 23:12, pages 4162-4173.
Read now
Jutta Deckert & Kevin Struhl. (2002) Targeted Recruitment of Rpd3 Histone Deacetylase Represses Transcription by Inhibiting Recruitment of Swi/Snf, SAGA, and TATA Binding Protein. Molecular and Cellular Biology 22:18, pages 6458-6470.
Read now
Chang-Hui Shen, Benoit P. Leblanc, Carolyn Neal, Ramin Akhavan & David J. Clark. (2002) Targeted Histone Acetylation at the Yeast CUP1 Promoter Requires the Transcriptional Activator, the TATA Boxes, and the Putative Histone Acetylase Encoded by SPT10. Molecular and Cellular Biology 22:18, pages 6406-6416.
Read now
Andrea R. Ricci, Julie Genereaux & Christopher J. Brandl. (2002) Components of the SAGA Histone Acetyltransferase Complex Are Required for Repressed Transcription of ARG1 in Rich Medium. Molecular and Cellular Biology 22:12, pages 4033-4042.
Read now

Articles from other publishers (142)

Yueyan Hu, Zhongjiao Liu, Shaohua Xu, Qinqin Zhao, Guodong Liu, Xin Song, Yinbo Qu & Yuqi Qin. (2023) The interaction between the histone acetyltransferase complex Hat1‐Hat2 and transcription factor AmyR provides a molecular brake to regulate amylase gene expression. Molecular Microbiology 119:4, pages 471-491.
Crossref
Amanda Garrido, Eunjeong Kim, Ana Teijeiro, Paula Sánchez Sánchez, Rosa Gallo, Ajay Nair, María Matamala Montoya, Cristian Perna, Guillermo P. Vicent, Javier Muñoz, Ramón Campos-Olivas, Johannes C. Melms, Benjamin Izar, Robert F. Schwabe & Nabil Djouder. (2022) Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis. Journal of Hepatology 76:4, pages 850-861.
Crossref
Sathish Kumar Mungamuri & Kotikalapudi Nagasuryaprasad. 2021. Epigenetics and Metabolomics. Epigenetics and Metabolomics 279 296 .
Giedrė Valiulienė, Aida Vitkevičienė & Rūta Navakauskienė. (2020) The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells. European Journal of Pharmacology 889, pages 173641.
Crossref
Mert Duman, Margot Martinez‐Moreno, Claire Jacob & Nikos Tapinos. (2020) Functions of histone modifications and histone modifiers in Schwann cells. Glia 68:8, pages 1584-1595.
Crossref
Callum J. O’Kane, Rachel Weild & Edel M. Hyland. (2020) Chromatin Structure and Drug Resistance in Candida spp.. Journal of Fungi 6:3, pages 121.
Crossref
Yongjiang Wu, Yawang Sun, Xianwen Dong, Jingbo Chen, Zili Wang, Juncai Chen & Guozhong Dong. (2020) The Synergism of PGN, LTA and LPS in Inducing Transcriptome Changes, Inflammatory Responses and a Decrease in Lactation as Well as the Associated Epigenetic Mechanisms in Bovine Mammary Epithelial Cells. Toxins 12:6, pages 387.
Crossref
Yongjiang Wu, Jingbo Chen, Yawang Sun, Xianwen Dong, Zili Wang, Juncai Chen & Guozhong Dong. (2020) PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells. Toxins 12:4, pages 238.
Crossref
Nathalie Acevedo, Paolo Frumento, Hani Harb, Bilal Alashkar Alhamwe, Catharina Johansson, Lisa Eick, Johan Alm, Harald Renz, Annika Scheynius & Daniel Potaczek. (2019) Histone Acetylation of Immune Regulatory Genes in Human Placenta in Association with Maternal Intake of Olive Oil and Fish Consumption. International Journal of Molecular Sciences 20:5, pages 1060.
Crossref
Sathish Kumar Mungamuri. 2019. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy 133 157 .
Hui He, Zhiping Hu, Han Xiao, Fangfang Zhou & Binbin Yang. (2018) The tale of histone modifications and its role in multiple sclerosis. Human Genomics 12:1.
Crossref
Eric Salgado, Xuehai Bian, Amber Feng, Hyunsuk Shim & Zhongxing Liang. (2018) HDAC9 overexpression confers invasive and angiogenic potential to triple negative breast cancer cells via modulating microRNA-206. Biochemical and Biophysical Research Communications 503:2, pages 1087-1091.
Crossref
Paul J. Wood, Robyn Strong, Grant A. McArthur, Michael Michael, Elizabeth Algar, Andrea Muscat, Lin Rigby, Melissa Ferguson & David M. Ashley. (2018) A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors. Cancer Chemotherapy and Pharmacology 82:3, pages 493-503.
Crossref
Yii Leng Chua & John C. Gray. 2018. Annual Plant Reviews online. Annual Plant Reviews online 79 111 .
Josipa Nemet, Nikolina Vidan & Mary Sopta. (2017) A meta-analysis reveals complex regulatory properties at Taf14-repressed genes. BMC Genomics 18:1.
Crossref
Chiara Zagni, Venerando Pistarà, Luciana A. Oliveira, Rogerio M. Castilho, Giovanni Romeo, Ugo Chiacchio & Antonio Rescifina. (2017) Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design. European Journal of Medicinal Chemistry 141, pages 188-196.
Crossref
Claire Jacob. (2017) Chromatin-remodeling enzymes in control of Schwann cell development, maintenance and plasticity. Current Opinion in Neurobiology 47, pages 24-30.
Crossref
Per Flodby, Changgong Li, Yixin Liu, Hongjun Wang, Megan E. Rieger, Parviz Minoo, Edward D. Crandall, David K. Ann, Zea Borok & Beiyun Zhou. (2017) Cell-specific expression of aquaporin-5 (Aqp5) in alveolar epithelium is directed by GATA6/Sp1 via histone acetylation. Scientific Reports 7:1.
Crossref
M. Bolotin-Fukuhara. (2017) Thirty years of the HAP2/3/4/5 complex. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:5, pages 543-559.
Crossref
Marinus te Pas, Ole Madsen, Mario Calus & Mari Smits. (2017) The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype. International Journal of Molecular Sciences 18:2, pages 472.
Crossref
Fernanda Wisnieski, Danielle Queiroz Calcagno, Mariana Ferreira Leal, Leonardo Caires Santos, Carolina Oliveira Gigek, Elizabeth Suchi Chen, Sâmia Demachki, Ricardo Artigiani, Paulo Pimentel Assumpção, Laércio Gomes Lourenço, Rommel Rodríguez Burbano & Marília Cardoso Smith. (2015) CDKN1A histone acetylation and gene expression relationship in gastric adenocarcinomas. Clinical and Experimental Medicine 17:1, pages 121-129.
Crossref
Valérie Brügger, Mert Duman, Maëlle Bochud, Emmanuelle Münger, Manfred Heller, Sophie Ruff & Claire Jacob. (2017) Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nature Communications 8:1.
Crossref
Shinji Toki, Kasia Goleniewska, Sara Reiss, Weisong Zhou, Dawn C Newcomb, Melissa H Bloodworth, Matthew T Stier, Kelli L Boyd, Vasiliy V Polosukhin, Sriram Subramaniam & R Stokes PeeblesJrJr. (2016) The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation. Thorax 71:7, pages 633-645.
Crossref
Daniel H. Gonzalez. 2016. Plant Transcription Factors. Plant Transcription Factors 3 11 .
Tianyi Zhang, Sarah Cooper & Neil Brockdorff. (2015) The interplay of histone modifications – writers that read. EMBO reports 16:11, pages 1467-1481.
Crossref
H. Irem Baymaz, Ino D. Karemaker & Michiel Vermeulen. (2015) Perspective on unraveling the versatility of ‘co-repressor’ complexes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:8, pages 1051-1056.
Crossref
Younis M. Khan, Paul Kirkham, Peter J. Barnes & Ian M. Adcock. (2014) Brd4 Is Essential for IL-1β-Induced Inflammation in Human Airway Epithelial Cells. PLoS ONE 9:4, pages e95051.
Crossref
Kaimeng Huang, Jinping Jia, Changwei Wu, Mingze Yao, Min Li, Jingji Jin, Cizhong Jiang, Yong Cai, Duanqing Pei, Guangjin Pan & Hongjie Yao. (2013) Ribosomal RNA Gene Transcription Mediated by the Master Genome Regulator Protein CCCTC-binding Factor (CTCF) Is Negatively Regulated by the Condensin Complex. Journal of Biological Chemistry 288:36, pages 26067-26077.
Crossref
Nicola Reynolds, Aoife O'Shaughnessy & Brian Hendrich. (2013) Transcriptional repressors: multifaceted regulators of gene expression. Development 140:3, pages 505-512.
Crossref
Shabana I. Khan, Pranapda Aumsuwan, Ikhlas A. Khan, Larry A. Walker & Asok K. Dasmahapatra. (2011) Epigenetic Events Associated with Breast Cancer and Their Prevention by Dietary Components Targeting the Epigenome. Chemical Research in Toxicology 25:1, pages 61-73.
Crossref
Azharul Islam, Emma L Turner, Johannes Menzel, Mackenzie E Malo & Troy AA Harkness. (2011) Antagonistic Gcn5-Hda1 interactions revealed by mutations to the Anaphase Promoting Complex in yeast. Cell Division 6:1.
Crossref
Mikko Arvas, Tiina Pakula, Bart Smit, Jari Rautio, Heini Koivistoinen, Paula Jouhten, Erno Lindfors, Marilyn Wiebe, Merja Penttilä & Markku Saloheimo. (2011) Correlation of gene expression and protein production rate - a system wide study. BMC Genomics 12:1.
Crossref
Emily J. Parnell & David J. Stillman. (2011) Shields up: the Tup1–Cyc8 repressor complex blocks coactivator recruitment: Figure 1.. Genes & Development 25:23, pages 2429-2435.
Crossref
Jacques P. Bothma, Joe Magliocco & Michael Levine. (2011) The Snail Repressor Inhibits Release, Not Elongation, of Paused Pol II in the Drosophila Embryo. Current Biology 21:18, pages 1571-1577.
Crossref
Jingli Hou, Congran Feng, Zhonghua Li, Qinghong Fang, Huihui Wang, Guoxian Gu, Yikang Shi, Pi Liu, Feng Xu, Zheng Yin, Jie Shen & Peng Wang. (2011) Structure-based optimization of click-based histone deacetylase inhibitors. European Journal of Medicinal Chemistry 46:8, pages 3190-3200.
Crossref
You Mie Lee. (2011) Control of RUNX3 by histone methyltransferases. Journal of Cellular Biochemistry 112:2, pages 394-400.
Crossref
Yael Katan-Khaykovich & Kevin Struhl. (2011) Splitting of H3–H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange. Proceedings of the National Academy of Sciences 108:4, pages 1296-1301.
Crossref
George Locke, Denis Tolkunov, Zarmik Moqtaderi, Kevin Struhl & Alexandre V. Morozov. (2010) High-throughput sequencing reveals a simple model of nucleosome energetics. Proceedings of the National Academy of Sciences 107:49, pages 20998-21003.
Crossref
Xiaochun FanZarmik MoqtaderiYi JinYong Zhang, X. Shirley Liu & Kevin Struhl. (2010) Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3’-end formation. Proceedings of the National Academy of Sciences 107:42, pages 17945-17950.
Crossref
Shahper N. Khan & Asad U. Khan. (2010) Role of histone acetylation in cell physiology and diseases: An update. Clinica Chimica Acta 411:19-20, pages 1401-1411.
Crossref
Clàudia Ruiz-Roig, Cristina Viéitez, Francesc Posas & Eulàlia De Nadal. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Molecular Microbiology 76:4, pages 1049-1062.
Crossref
Mathieu Dalvai & Kerstin Bystricky. (2010) The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer. Journal of Mammary Gland Biology and Neoplasia 15:1, pages 19-33.
Crossref
Michelle Esposito, Paulina Konarzewska, Oluwafemi Odeyale & Chang-Hui Shen. (2010) Gene-wide histone acetylation at the yeast INO1 requires the transcriptional activator Ino2p. Biochemical and Biophysical Research Communications 391:2, pages 1285-1290.
Crossref
Melanie Grably & David Engelberg. 2010. Molecular and Cell Biology Methods for Fungi. Molecular and Cell Biology Methods for Fungi 211 224 .
Georg Feldmann & Anirban Maitra. 2010. Drug Discovery in Pancreatic Cancer. Drug Discovery in Pancreatic Cancer 181 204 .
Inga Kadish. 2010. Epigenetics of Aging. Epigenetics of Aging 41 50 .
Kitty F Verzijlbergen, Alex W Faber, Iris JE Stulemeijer & Fred van Leeuwen. (2009) Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae. BMC Molecular Biology 10:1.
Crossref
Selena B. Kremer & David S. Gross. (2009) SAGA and Rpd3 Chromatin Modification Complexes Dynamically Regulate Heat Shock Gene Structure and Expression. Journal of Biological Chemistry 284:47, pages 32914-32931.
Crossref
Yong Zhang, Zarmik Moqtaderi, Barbara P Rattner, Ghia Euskirchen, Michael Snyder, James T Kadonaga, X Shirley Liu & Kevin Struhl. (2009) Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo. Nature Structural & Molecular Biology 16:8, pages 847-852.
Crossref
Anita Ciurciu, István Tombácz, Cristina Popescu & Imre Boros. (2009) GAL4 induces transcriptionally active puff in the absence of dSAGA- and ATAC-specific chromatin acetylation in the Drosophila melanogaster polytene chromosome. Chromosoma 118:4, pages 513-526.
Crossref
Christine A. Iacobuzio-Donahue. (2009) Epigenetic Changes in Cancer. Annual Review of Pathology: Mechanisms of Disease 4:1, pages 229-249.
Crossref
Eliana B Gómez, Rebecca L Nugent, Sebastián Laria & Susan L Forsburg. (2008) Schizosaccharomyces pombe Histone Acetyltransferase Mst1 (KAT5) Is an Essential Protein Required for Damage Response and Chromosome Segregation . Genetics 179:2, pages 757-771.
Crossref
Sandra N. Garcia & Olivia Pereira-Smith. (2008) MRGing Chromatin Dynamics and Cellular Senescence. Cell Biochemistry and Biophysics 50:3, pages 133-141.
Crossref
Heather E. Peckham, Robert E. Thurman, Yutao Fu, John A. Stamatoyannopoulos, William Stafford Noble, Kevin Struhl & Zhiping Weng. (2007) Nucleosome positioning signals in genomic DNA. Genome Research 17:8, pages 1170-1177.
Crossref
V El-Khoury, G Breuzard, N Fourré & J Dufer. (2007) The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. British Journal of Cancer 97:4, pages 562-573.
Crossref
Mona D. ShahbazianMichael Grunstein. (2007) Functions of Site-Specific Histone Acetylation and Deacetylation. Annual Review of Biochemistry 76:1, pages 75-100.
Crossref
Bing Li, Michael Carey & Jerry L. Workman. (2007) The Role of Chromatin during Transcription. Cell 128:4, pages 707-719.
Crossref
Janice M. Mehnert & Wm Kevin Kelly. (2007) Histone Deacetylase Inhibitors: Biology and Mechanism of Action. The Cancer Journal 13:1, pages 23-29.
Crossref
Chhabi K. Govind, Fan Zhang, Hongfang Qiu, Kimberly Hofmeyer & Alan G. Hinnebusch. (2007) Gcn5 Promotes Acetylation, Eviction, and Methylation of Nucleosomes in Transcribed Coding Regions. Molecular Cell 25:1, pages 31-42.
Crossref
Eulàlia de Nadal & Francesc Posas. 2008. Stress-Activated Protein Kinases. Stress-Activated Protein Kinases 81 97 .
Woojin An. 2007. Chromatin and Disease. Chromatin and Disease 355 374 .
Eleonora Agricola, Loredana Verdone, Ernesto Di Mauro & Micaela Caserta. (2006) H4 acetylation does not replace H3 acetylation in chromatin remodelling and transcription activation of Adr1-dependent genes. Molecular Microbiology 62:5, pages 1433-1446.
Crossref
R. Erik Edens, Selma Dagtas & Kathleen M. Gilbert. (2006) Histone deacetylase inhibitors induce antigen specific anergy in lymphocytes: A comparative study. International Immunopharmacology 6:11, pages 1673-1681.
Crossref
Thanuja Krishnamoorthy, Xin Chen, Jerome Govin, Wang L. Cheung, Jean Dorsey, Karen Schindler, Edward Winter, C. David Allis, Vincent Guacci, Saadi Khochbin, Margaret T. Fuller & Shelley L. Berger. (2006) Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes & Development 20:18, pages 2580-2592.
Crossref
Tania M. MalavéSharon Y.R. Dent. (2006) Transcriptional repression by Tup1–Ssn6This paper is one of a selection of papers published in this Special Issue, entitled 27th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.. Biochemistry and Cell Biology 84:4, pages 437-443.
Crossref
Marc A. Schwabish & Kevin Struhl. (2006) Asf1 Mediates Histone Eviction and Deposition during Elongation by RNA Polymerase II. Molecular Cell 22:3, pages 415-422.
Crossref
Michel Herranz & Manel Esteller. (2006) New therapeutic targets in cancer: the epigenetic connection. Clinical & Translational Oncology 8:4, pages 242-249.
Crossref
Catherine B. Millar, Feng Xu, Kangling Zhang & Michael Grunstein. (2006) Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast. Genes & Development 20:6, pages 711-722.
Crossref
Calley L. Hirsch, Erin L. Smith-Windsor & Keith Bonham. (2006) Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. International Journal of Cancer 118:3, pages 547-554.
Crossref
Tamara Tripic, Diane G. Edmondson, Judith K. Davie, Brian D. Strahl & Sharon Y.R. Dent. (2006) The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochemical and Biophysical Research Communications 339:3, pages 905-914.
Crossref
Paolo Struffi & David N. Arnosti. (2005) Functional Interaction between the Drosophila Knirps Short Range Transcriptional Repressor and RPD3 Histone Deacetylase. Journal of Biological Chemistry 280:49, pages 40757-40765.
Crossref
Tapio Nuutinen, Tiina Suuronen, Sergiy Kyrylenko, Jari Huuskonen & Antero Salminen. (2005) Induction of clusterin/apoJ expression by histone deacetylase inhibitors in neural cells. Neurochemistry International 47:8, pages 528-538.
Crossref
Joseph T. Wade, Nikos B. Reppas, George M. Church & Kevin Struhl. (2005) Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites . Genes & Development 19:21, pages 2619-2630.
Crossref
Daeyoup Lee, Elena Ezhkova, Bing Li, Samantha G. Pattenden, William P. Tansey & Jerry L. Workman. (2005) The Proteasome Regulatory Particle Alters the SAGA Coactivator to Enhance Its Interactions with Transcriptional Activators. Cell 123:3, pages 423-436.
Crossref
Ryan M. Raisner, Paul D. Hartley, Marc D. Meneghini, Marie Z. Bao, Chih Long Liu, Stuart L. Schreiber, Oliver J. Rando & Hiten D. Madhani. (2005) Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin. Cell 123:2, pages 233-248.
Crossref
Haiying Zhang, Douglas N. Roberts & Bradley R. Cairns. (2005) Genome-Wide Dynamics of Htz1, a Histone H2A Variant that Poises Repressed/Basal Promoters for Activation through Histone Loss. Cell 123:2, pages 219-231.
Crossref
R. Nicholas Laribee & Michael J. Klemsz. (2005) Histone H4 HDAC activity is necessary for expression of the PU.1 gene. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1730:3, pages 226-234.
Crossref
Dmitry K. Pokholok, Christopher T. Harbison, Stuart Levine, Megan Cole, Nancy M. Hannett, Tong Ihn Lee, George W. Bell, Kimberly Walker, P. Alex Rolfe, Elizabeth Herbolsheimer, Julia Zeitlinger, Fran Lewitter, David K. Gifford & Richard A. Young. (2005) Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast. Cell 122:4, pages 517-527.
Crossref
Yumin Teng, Yachuan Yu, Jose A. Ferreiro & Raymond Waters. (2005) Histone acetylation, chromatin remodelling, transcription and nucleotide excision repair in S. cerevisiae: studies with two model genes. DNA Repair 4:8, pages 870-883.
Crossref
Loredana Verdone, Micaela Caserta & Ernesto Di Mauro. (2005) Role of histone acetylation in the control of gene expression. Biochemistry and Cell Biology 83:3, pages 344-353.
Crossref
Antonin Morillon, Nickoletta Karabetsou, Anitha Nair & Jane Mellor. (2005) Dynamic Lysine Methylation on Histone H3 Defines the Regulatory Phase of Gene Transcription. Molecular Cell 18:6, pages 723-734.
Crossref
Edward A. Sekinger, Zarmik Moqtaderi & Kevin Struhl. (2005) Intrinsic Histone-DNA Interactions and Low Nucleosome Density Are Important for Preferential Accessibility of Promoter Regions in Yeast. Molecular Cell 18:6, pages 735-748.
Crossref
Christine Sacerdot, G�raldine Mercier, Anne-Laure Todeschini, Marie Dutreix, Mathias Springer & Pascale Lesage. (2005) Impact of ionizing radiation on the life cycle ofSaccharomyces cerevisiae Ty1 retrotransposon. Yeast 22:6, pages 441-455.
Crossref
Hui-Ching Kuo, John D. Moore & Jocelyn E. Krebs. (2005) Histone H2A and Spt10 Cooperate to Regulate Induction and Autoregulation of the CUP1 Metallothionein. Journal of Biological Chemistry 280:1, pages 104-111.
Crossref
Shuang Chang & Craig S. Pikaard. (2005) Transcript Profiling in Arabidopsis Reveals Complex Responses to Global Inhibition of DNA Methylation and Histone Deacetylation*[boxs]. Journal of Biological Chemistry 280:1, pages 796-804.
Crossref
Amos Tanay, Israel Steinfeld, Martin Kupiec & Ron Shamir. (2005) Integrative analysis of genome‐wide experiments in the context of a large high‐throughput data compendium. Molecular Systems Biology 1:1.
Crossref
E Weisberg, L Catley, J Kujawa, P Atadja, S Remiszewski, P Fuerst, C Cavazza, K Anderson & J D Griffin. (2004) Histone deacetylase inhibitor NVP-LAQ824 has significant activity against myeloid leukemia cells in vitro and in vivo. Leukemia 18:12, pages 1951-1963.
Crossref
Kapil Bhalla & Alan List. (2004) Histone deacetylase inhibitors in myelodysplastic syndrome. Best Practice & Research Clinical Haematology 17:4, pages 595-611.
Crossref
R.C. Kumar & M.K. Thakur. (2004) Sex steroids reduce DNaseI accessibility of androgen receptor promoter in adult male mice brain. Molecular Brain Research 131:1-2, pages 1-7.
Crossref
Arnold Kristjuhan & Jesper Q Svejstrup. (2004) Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo. The EMBO Journal 23:21, pages 4243-4252.
Crossref
Karine Lemieux & Luc Gaudreau. (2004) Targeting of Swi/Snf to the yeast GAL1 UASG requires the Mediator, TAFIIs, and RNA polymerase II. The EMBO Journal 23:20, pages 4040-4050.
Crossref
Wei Huang, Vachaspati Mishra, Sanjay Batra, Ishan Dillon & Kamal D. Mehta. (2004) Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner. Journal of Lipid Research 45:8, pages 1519-1527.
Crossref
Sharmila Shankar & Rakesh K Srivastava. (2004) Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resistance Updates 7:2, pages 139-156.
Crossref
Johannes Graumann, Leslie A. Dunipace, Jae Hong Seol, W. Hayes McDonald, John R. YatesIIIIII, Barbara J. Wold & Raymond J. Deshaies. (2004) Applicability of Tandem Affinity Purification MudPIT to Pathway Proteomics in Yeast. Molecular & Cellular Proteomics 3:3, pages 226-237.
Crossref
Sadri Znaidi, Benoit Pelletier, Yukio Mukai & Simon Labbé. (2004) The Schizosaccharomyces pombe Corepressor Tup11 Interacts with the Iron-responsive Transcription Factor Fep1. Journal of Biological Chemistry 279:10, pages 9462-9474.
Crossref
Abdelhalim Boukaba, Elena I. Georgieva, Fiona A. Myers, Alan W. Thorne, Gerardo López-Rodas, Colyn Crane-Robinson & Luis Franco. (2004) A Short-range Gradient of Histone H3 Acetylation and Tup1p Redistribution at the Promoter of the Saccharomyces cerevisiae SUC2 Gene. Journal of Biological Chemistry 279:9, pages 7678-7684.
Crossref
Carol M. Kiekhaefer, Meghan E. Boyer, Kirby D. Johnson & Emery H. Bresnick. (2004) A WW Domain-binding Motif within the Activation Domain of the Hematopoietic Transcription Factor NF-E2 Is Essential for Establishment of a Tissue-specific Histone Modification Pattern. Journal of Biological Chemistry 279:9, pages 7456-7461.
Crossref
Kathryn L. Huisinga & B. Franklin Pugh. (2004) A Genome-Wide Housekeeping Role for TFIID and a Highly Regulated Stress-Related Role for SAGA in Saccharomyces cerevisiae. Molecular Cell 13:4, pages 573-585.
Crossref
Eulàlia de Nadal, Meritxell Zapater, Paula M. Alepuz, Lauro Sumoy, Glòria Mas & Francesc Posas. (2004) The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes. Nature 427:6972, pages 370-374.
Crossref
Judith K Davie & Sharon Y.R Dent. 2004. 145 163 .
D. N. Arnosti. 2004. Transcription Factors. Transcription Factors 33 67 .
Jose Russo & Irma H. RussoJose Russo & Irma H. Russo. 2004. Molecular Basis of Breast Cancer. Molecular Basis of Breast Cancer 49 88 .
Thomas A. Mennella, Lee G. Klinkenberg & Richard S. Zitomer. (2003) Recruitment of Tup1-Ssn6 by Yeast Hypoxic Genes and Chromatin-Independent Exclusion of TATA Binding Protein. Eukaryotic Cell 2:6, pages 1288-1303.
Crossref
Judith K. Davie, Diane G. Edmondson, Cherie B. Coco & Sharon Y.R. Dent. (2003) Tup1-Ssn6 Interacts with Multiple Class I Histone Deacetylases in Vivo. Journal of Biological Chemistry 278:50, pages 50158-50162.
Crossref
Tiina Suuronen, Jari Huuskonen, Rea Pihlaja, Sergiy Kyrylenko & Antero Salminen. (2003) Regulation of microglial inflammatory response by histone deacetylase inhibitors. Journal of Neurochemistry 87:2, pages 407-416.
Crossref
John J Heikkila. (2003) Expression and function of small heat shock protein genes during Xenopus development. Seminars in Cell & Developmental Biology 14:5, pages 259-266.
Crossref
S. Zeilinger, M. Schmoll, M. Pail, R. L. Mach & C. P. Kubicek. (2003) Nucleosome transactions on the Hypocrea jecorina ( Trichoderma reesei) cellulase promoter cbh2 associated with cellulase induction. Molecular Genetics and Genomics 270:1, pages 46-55.
Crossref
Niveen M Mulholland, Edlyn Soeth & Catharine L Smith. (2003) Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation. Oncogene 22:31, pages 4807-4818.
Crossref
Claire Bertrand, Catherine Bergounioux, Séverine Domenichini, Marianne Delarue & Dao-Xiu Zhou. (2003) Arabidopsis Histone Acetyltransferase AtGCN5 Regulates the Floral Meristem Activity through the WUSCHEL/AGAMOUS Pathway. Journal of Biological Chemistry 278:30, pages 28246-28251.
Crossref
James R. Lambert & Steven K. Nordeen. (2003) CBP Recruitment and Histone Acetylation in Differential Gene Induction by Glucocorticoids and Progestins. Molecular Endocrinology 17:6, pages 1085-1094.
Crossref
Hans Reinke & Wolfram Hörz. (2003) Histones Are First Hyperacetylated and Then Lose Contact with the Activated PHO5 Promoter. Molecular Cell 11:6, pages 1599-1607.
Crossref
Hans-Joachim Schüller. (2003) Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae. Current Genetics 43:3, pages 139-160.
Crossref
Daniel H. Ovakim & John J. Heikkila. (2003) Effect of histone deacetylase inhibitors on heat shock protein gene expression duringXenopus development. genesis 36:2, pages 88-96.
Crossref
Yukio Mukai, Judith K. Davie & Sharon Y.R. Dent. (2003) Physical and Functional Interaction of the Yeast Corepressor Tup1 with mRNA 5′-Triphosphatase. Journal of Biological Chemistry 278:21, pages 18895-18901.
Crossref
Pratibha B. Hebbar & Trevor K. Archer. (2003) Chromatin remodeling by nuclear receptors. Chromosoma 111:8, pages 495-504.
Crossref
Alexander M. Erkine & David S. Gross. (2003) Dynamic Chromatin Alterations Triggered by Natural and Synthetic Activation Domains. Journal of Biological Chemistry 278:10, pages 7755-7764.
Crossref
Huck Hui Ng, David N. Ciccone, Katrina B. Morshead, Marjorie A. Oettinger & Kevin Struhl. (2003) Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position-effect variegation. Proceedings of the National Academy of Sciences 100:4, pages 1820-1825.
Crossref
Miki Hiroi & Yoshihiro Ohmori. (2003) The Transcriptional Coactivator CREB-binding Protein Cooperates with STAT1 and NF-κB for Synergistic Transcriptional Activation of the CXC Ligand 9/Monokine Induced by Interferon-γ Gene. Journal of Biological Chemistry 278:1, pages 651-660.
Crossref
Hiroshi Sakurai & Toshio Fukasawa. (2003) Artificial recruitment of certain Mediator components affects requirement of basal transcription factor IIE. Genes to Cells 8:1, pages 41-50.
Crossref
Rakesh SingalJane M. vanWertLarry FerdinandJrJr. (2002) Methylation of α-type embryonic globin gene απrepresses transcription in primary erythroid cells. Blood 100:12, pages 4217-4222.
Crossref
Daeyoup Lee, Chunghun Lim, Taegun Seo, Hyockman Kwon, Hyesun Min & Joonho Choe. (2002) The Viral Oncogene Human Papillomavirus E7 Deregulates Transcriptional Silencing by Brm-related Gene 1 via Molecular Interactions. Journal of Biological Chemistry 277:50, pages 48842-48848.
Crossref
Ting Chen, Hui Sun, Jun Lu, Yanmei Zhao, Dan Tao, Xiaoxue Li & Baiqu Huang. (2002) Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. Archives of Biochemistry and Biophysics 408:2, pages 171-176.
Crossref
Francesca Puppo, Paola Griseri, Mirco Fanelli, Francesca Schena, Giovanni Romeo, PierGiuseppe Pelicci, Isabella Ceccherini, Roberto Ravazzolo & Giovanna Patrone. (2002) Cell-line specific chromatin acetylation at the Sox10-Pax3 enhancer site modulates the RET proto-oncogene expression . FEBS Letters 523:1-3, pages 123-127.
Crossref
Stavros Lomvardas & Dimitris Thanos. (2002) Modifying Gene Expression Programs by Altering Core Promoter Chromatin Architecture. Cell 110:2, pages 261-271.
Crossref
Jakob H Waterborg. (2002) Dynamics of histone acetylation in vivo. A function for acetylation turnover?. Biochemistry and Cell Biology 80:3, pages 363-378.
Crossref
Markus Proft & Kevin Struhl. (2002) Hog1 Kinase Converts the Sko1-Cyc8-Tup1 Repressor Complex into an Activator that Recruits SAGA and SWI/SNF in Response to Osmotic Stress. Molecular Cell 9:6, pages 1307-1317.
Crossref
Melissa A. Wilson, Andrea R. Ricci, Bonnie J. Deroo & Trevor K. Archer. (2002) The Histone Deacetylase Inhibitor Trichostatin A Blocks Progesterone Receptor-mediated Transactivation of the Mouse Mammary Tumor Virus Promoter in Vivo. Journal of Biological Chemistry 277:17, pages 15171-15181.
Crossref
Mario Mencı́a, Zarmik Moqtaderi, Joseph V Geisberg, Laurent Kuras & Kevin Struhl. (2002) Activator-Specific Recruitment of TFIID and Regulation of Ribosomal Protein Genes in Yeast. Molecular Cell 9:4, pages 823-833.
Crossref
Yael Katan-Khaykovich & Kevin Struhl. (2002) Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors. Genes & Development 16:6, pages 743-752.
Crossref
Luc E.G. Rietveld, Eric Caldenhoven & Hendrik G. Stunnenberg. (2002) In vivo repression of an erythroid-specific gene by distinct corepressor complexes . The EMBO Journal 21:6, pages 1389-1397.
Crossref
Krzysztof Masternak & Walter Reith. (2002) Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation. The EMBO Journal 21:6, pages 1379-1388.
Crossref
Anton Eberharter & Peter B Becker. (2002) Histone acetylation: a switch between repressive and permissive chromatin. EMBO reports 3:3, pages 224-229.
Crossref
Ola Hermanson, Christopher K Glass & Michael G Rosenfeld. (2002) Nuclear receptor coregulators: multiple modes of modification. Trends in Endocrinology & Metabolism 13:2, pages 55-60.
Crossref
Kristen Jepsen & Michael G. Rosenfeld. (2002) Biological roles and mechanistic actions of co-repressor complexes. Journal of Cell Science 115:4, pages 689-698.
Crossref
Kirby D Johnson & Emery H Bresnick. (2002) Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation. Methods 26:1, pages 27-36.
Crossref
Paul A. Marks, Richard A. Rifkind, Victoria M. Richon, Ronald Breslow, Thomas Miller & William K. Kelly. (2001) Histone deacetylases and cancer: causes and therapies. Nature Reviews Cancer 1:3, pages 194-202.
Crossref
Paul A. Marks, Victoria M. Richon, Ronald Breslow & Richard A. Rifkind. (2001) Histone deacetylase inhibitors as new cancer drugs. Current Opinion in Oncology 13:6, pages 477-483.
Crossref
Stefano Guandalini & Ranjana Gokhale. (2001) Update on immunologic basis of celiac disease. Current Opinion in Gastroenterology 17:6, pages 545-550.
Crossref
E. Camilla Forsberg & Emery H. Bresnick. (2001) Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world. BioEssays 23:9, pages 820-830.
Crossref
Edwin R. Smith, C. David Allis & John C. Lucchesi. (2001) Linking Global Histone Acetylation to the Transcription Enhancement of X-chromosomal Genes in Drosophila Males. Journal of Biological Chemistry 276:34, pages 31483-31486.
Crossref
Lynn A. Sheldon, Matthias Becker & Catharine L. Smith. (2001) Steroid Hormone Receptor-mediated Histone Deacetylation and Transcription at the Mouse Mammary Tumor Virus Promoter. Journal of Biological Chemistry 276:35, pages 32423-32426.
Crossref
Philip D Gregory. (2001) Transcription and chromatin converge: lessons from yeast genetics. Current Opinion in Genetics & Development 11:2, pages 142-147.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.