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Molecular and Cellular Biology Volume 22, 2002 - Issue 19
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DNA Dynamics and Chromosome Structure

DNA Methylation Has a Local Effect on Transcription and Histone Acetylation

Ryan A. IrvineDepartment of Urology and Department of Biochemistry and Molecular Biology, University of Southern California-Norris Cancer Center, Los Angeles, California90033
,
Iping G. LinDepartment of Urology and Department of Biochemistry and Molecular Biology, University of Southern California-Norris Cancer Center, Los Angeles, California90033
&
Chih-Lin HsiehDepartment of Urology and Department of Biochemistry and Molecular Biology, University of Southern California-Norris Cancer Center, Los Angeles, California90033Correspondence[email protected]
Pages 6689-6696 | Received 23 Apr 2002, Accepted 02 Jul 2002, Published online: 27 Mar 2023

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Lili Qing, Peng Xiong, Yumei Lu, Hongyan Jiang & Shengjie Nie. (2023) Sex-dependent association of DNA methylation in the coding region of the corticotropin-releasing hormone gene and schizophrenia spectrum disorder. Annals of Human Biology 50:1, pages 1-8.
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Crossref
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Gregory W. Peek & Trygve O. Tollefsbol. (2011) The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention. Clinical Epigenetics 2:2, pages 97-112.
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Crossref
Li ZhangYong DaiLinxian WangWujian PengYanliang ZhangYangxin OuJuanjuan Lu. (2011) CpG Array Analysis of Histone H3 Lysine 4 Trimethylation in Peripheral Blood Mononuclear Cells of Uremia Patients. DNA and Cell Biology 30:3, pages 179-186.
Crossref
Lei Xiong & Yinsheng Wang. (2011) Mapping post-translational modifications of histones H2A, H2B and H4 in Schizosaccharomyces pombe. International Journal of Mass Spectrometry 301:1-3, pages 159-165.
Crossref
Ai-niu Ma, Jie Lu, Xiang-jun Zhou & Yong-xiang Wang. (2011) Histone deacetylation directs DNA methylation in survivin gene silencing. Biochemical and Biophysical Research Communications 404:1, pages 268-272.
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Ryan A. Irvine, Cindy Okitsu & Chih-Lin Hsieh. 2011. Epigenetics Protocols. Epigenetics Protocols 213 223 .
Bethany L. Wienholz, Michael S. Kareta, Amir H. Moarefi, Catherine A. Gordon, Paul A. Ginno & Frédéric Chédin. (2010) DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo. PLoS Genetics 6:9, pages e1001106.
Crossref
Lei Xiong, Keyur K. Adhvaryu, Eric U. Selker & Yinsheng Wang. (2010) Mapping of Lysine Methylation and Acetylation in Core Histones of Neurospora crassa . Biochemistry 49:25, pages 5236-5243.
Crossref
S. K. Munro, C. M. Farquhar, M. D. Mitchell & A. P. Ponnampalam. (2010) Epigenetic regulation of endometrium during the menstrual cycle. Molecular Human Reproduction 16:5, pages 297-310.
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Crossref
Jee-Hye Choi, Na Young Min, Jina Park, Jin Hong Kim, Soo Hyun Park, Young Jong Ko, Yoonsung Kang, Young Joon Moon, Sangmyung Rhee, Seung Wook Ham, Ae Ja Park & Kwang-Ho Lee. (2010) TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116. Biochemical and Biophysical Research Communications 391:1, pages 449-454.
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Masaru Mitsui, Makiya Nishikawa, Lei Zang, Mitsuru Ando, Kayoko Hattori, Yuki Takahashi, Yoshihiko Watanabe & Yoshinobu Takakura. (2009) Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression. The Journal of Gene Medicine 11:5, pages 435-443.
Crossref
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Crossref
Samir K. Patra & Moshe Szyf. (2008) DNA methylation-mediated nucleosome dynamics and oncogenic Ras signaling. FEBS Journal 275:21, pages 5217-5235.
Crossref
Simonetta Friso & Sang-Woon Choi. 2008. Cancer Epigenetics. Cancer Epigenetics 79 93 .
Holger K. de Wolf, Nina Johansson, Anh-Thy Thong, Cor J. Snel, Enrico Mastrobattista, Wim E. Hennink & Gert Storm. (2008) Plasmid CpG Depletion Improves Degree and Duration of Tumor Gene Expression After Intravenous Administration of Polyplexes. Pharmaceutical Research 25:7, pages 1654-1662.
Crossref
Samir Kumar Patra, Aditi Patra, Federica Rizzi, Tapash Chandra Ghosh & Saverio Bettuzzi. (2008) Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development. Cancer and Metastasis Reviews 27:2, pages 315-334.
Crossref
B L Pike, T C Greiner, X Wang, D D Weisenburger, Y-H Hsu, G Renaud, T G Wolfsberg, M Kim, D J Weisenberger, K D Siegmund, W Ye, S Groshen, R Mehrian-Shai, J Delabie, W C Chan, P W Laird & J G Hacia. (2008) DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status. Leukemia 22:5, pages 1035-1043.
Crossref
Radosław Januchowski, Mikołaj Dąbrowski, Harold Ofori & Paweł P. Jagodzinski. (2007) Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells. Cancer Letters 246:1-2, pages 313-317.
Crossref
Takahiro Aoto, Noriko Saitoh, Takaya Ichimura, Hitoshi Niwa & Mitsuyoshi Nakao. (2006) Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation. Developmental Biology 298:2, pages 354-367.
Crossref
Yu. V. Vakhitova, S. V. Sadovnikov, R. S. Yamidanov & S. B. Seredenin. (2006) Cytosine demethylation in the tyrosine hydroxylase gene promoter in hypothalamus cells of rat brain under the action of 2-aminoadamantane compound Ladasten. Russian Journal of Genetics 42:7, pages 795-801.
Crossref
Rumiko Moriguchi, Kentaro Kogure, Akitada Iwasa, Hidetaka Akita & Hideyoshi Harashima. (2006) Non-linear pharmacodynamics in a non-viral gene delivery system: Positive non-linear relationship between dose and transfection efficiency. Journal of Controlled Release 110:3, pages 605-609.
Crossref
D. Tang, G.S. Sivko & J.W. DeWille. (2005) Promoter methylation reduces C/EBPδ (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors. Breast Cancer Research and Treatment 95:2, pages 161-170.
Crossref
Shoukang ZhuPascal J. Goldschmidt-ClermontChunming Dong. (2005) Inactivation of Monocarboxylate Transporter MCT3 by DNA Methylation in Atherosclerosis. Circulation 112:9, pages 1353-1361.
Crossref
Yuning Xiong, Sean C. Dowdy, Karl C. Podratz, Fan Jin, John R. Attewell, Norman L. Eberhardt & Shi-Wen Jiang. (2005) Histone Deacetylase Inhibitors Decrease DNA Methyltransferase-3B Messenger RNA Stability and Down-regulate De novo DNA Methyltransferase Activity in Human Endometrial Cells . Cancer Research 65:7, pages 2684-2689.
Crossref
Qi Fu, Robert A. McKnight, Xing Yu, Laiyi Wang, Christopher W. Callaway & Robert H. Lane. (2004) Uteroplacental insufficiency induces site-specific changes in histone H3 covalent modifications and affects DNA-histone H3 positioning in day 0 IUGR rat liver . Physiological Genomics 20:1, pages 108-116.
Crossref
Kangling Zhang, Joseph S. Siino, Patrick R. Jones, Peter M. Yau & E. Morton Bradbury. (2004) A mass spectrometric ?Western blot? to evaluate the correlations between histone methylation and histone acetylation. PROTEOMICS 4:12, pages 3765-3775.
Crossref
Yvonne Chan, Jason E. Fish, Cheryl D'Abreo, Steven Lin, G. Brett Robb, Anouk-Martine Teichert, Fotula Karantzoulis-Fegaras, Angela Keightley, Brent M. Steer & Philip A. Marsden. (2004) The Cell-specific Expression of Endothelial Nitric-oxide Synthase. Journal of Biological Chemistry 279:33, pages 35087-35100.
Crossref
Bradley L. Hodges, Kristin M. Taylor, Macy F. Joseph, Sarah A. Bourgeois & Ronald K. Scheule. (2004) Long-term Transgene Expression from Plasmid DNA Gene Therapy Vectors Is Negatively Affected by CpG Dinucleotides. Molecular Therapy 10:2, pages 269-278.
Crossref
Elizabeth J. Corwin. (2016) The Concept of Epigenetics and Its Role in the Development of Cardiovascular Disease: Commentary on “New and Emerging Theories of Cardiovascular Disease”. Biological Research For Nursing 6:1, pages 11-16.
Crossref
Tetsuji Nakagawachi, Hidenobu Soejima, Takeshi Urano, Wei Zhao, Ken Higashimoto, Yuji Satoh, Shiroh Matsukura, Shinichi Kudo, Yoshihiko Kitajima, Haruhito Harada, Koichi Furukawa, Hideki Matsuzaki, Mitsuru Emi, Yusaku Nakabeppu, Kohji Miyazaki, Mutsuo Sekiguchi & Tsunehiro Mukai. (2003) Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer. Oncogene 22:55, pages 8835-8844.
Crossref
Hiroyuki Kamiya, Hidetaka Akita & Hideyoshi Harashima. (2003) Pharmacokinetic and pharmacodynamic considerations in gene therapy. Drug Discovery Today 8:21, pages 990-996.
Crossref
Michael C Fr??hwald. (2003) DNA Methylation Patterns in Cancer. American Journal of PharmacoGenomics 3:4, pages 245-260.
Crossref

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