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Molecular and Cellular Biology Volume 22, 2002 - Issue 2
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Transcriptional Regulation

Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run, in Caenorhabditis elegans

Seunghee Nam1 Department of Biology, Yonsei University, Seoul120-749
,
Yun-Hye Jin2 Department of Biochemistry, School of Medicine, and Medical Research Institute
,
Qing-Lin Li2 Department of Biochemistry, School of Medicine, and Medical Research Institute
,
Kwang-Youl Lee2 Department of Biochemistry, School of Medicine, and Medical Research Institute
,
Goo-Bo Jeong3 Department of Anatomy, School of Medicine, Chungbuk National University, Cheongju361-763, South Korea
,
Yoshiaki Ito4 Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto, Japan
,
Junho Lee1 Department of Biology, Yonsei University, Seoul120-749Correspondence[email protected] [email protected]
&
Suk-Chul Bae2 Department of Biochemistry, School of Medicine, and Medical Research InstituteCorrespondence[email protected] [email protected]
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Pages 547-554 | Received 29 Jun 2001, Accepted 11 Oct 2001, Published online: 28 Mar 2023

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Bumnoh Lee & Nam Jeong Cho. (2005) Analysis of the Caenorhabditis elegans dlk‐1 gene expression. Integrative Biosciences 9:3, pages 107-111.
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Wei Wu, Jiejie Sun, Miren Dong, Qian Yang, Wenwen Yang, Tong Zhang, Lingling Wang & Linsheng Song. (2023) CgTNF-2 promotes the proliferation of haemocytes by regulating the expressions of CgRunx and cell cycle related genes in the Pacific oyster Crassostrea gigas. Fish & Shellfish Immunology 132, pages 108478.
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Hongyang Yi, Yuhao He, Qionghua Zhu & Liang Fang. (2022) RUNX Proteins as Epigenetic Modulators in Cancer. Cells 11:22, pages 3687.
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Ranjan Sahu, Sanjat Kumar Sahu & Sudhansu Sekhar Nishank. (2021) de novo transcriptome profile of two earthworms Lampito mauritii and Drawida calebi during regeneration. Biochemistry and Biophysics Reports 27, pages 101092.
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Christina M. May, Erik B. Van den Akker & Bas J. Zwaan. (2021) The Transcriptome in Transition: Global Gene Expression Profiles of Young Adult Fruit Flies Depend More Strongly on Developmental Than Adult Diet. Frontiers in Ecology and Evolution 9.
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Arash Padash, Raheleh Halabian, Ali Salimi, Negar Motakef Kazemi & Mohsen Shahrousvand. (2020) Osteogenic differentiation of mesenchymal stem cells on the bimodal polymer polyurethane/polyacrylonitrile containing cellulose phosphate nanowhisker. Human Cell 34:2, pages 310-324.
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Sarah B. Robinson, Osama Refai, J. Andrew Hardaway, Sarah Sturgeon, Tessa Popay, Daniel P. Bermingham, Phyllis Freeman, Jane Wright & Randy D. Blakely. (2019) Dopamine-dependent, swimming-induced paralysis arises as a consequence of loss of function mutations in the RUNX transcription factor RNT-1. PLOS ONE 14:5, pages e0216417.
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Zhe Zheng, Xiaodong Du, Xinwei Xiong, Yu Jiao, Yuewen Deng, Qingheng Wang & Ronglian Huang. (2017) PmRunt regulated by Pm-miR-183 participates in nacre formation possibly through promoting the expression of collagen VI-like and Nacrein in pearl oyster Pinctada martensii. PLOS ONE 12:6, pages e0178561.
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Brandon Praslicka, Jeremy S. Harmson, Joohyun Kim, Vittobai Rashika Rangaraj, Aikseng Ooi & Chris R. Gissendanner. (2017) Binding Site Analysis of the Caenorhabditis elegans NR4A Nuclear Receptor NHR-6 During Development. Nuclear Receptor Research 4.
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Linda Shyue Huey Chuang, Kosei Ito & Yoshiaki Ito. 2017. RUNX Proteins in Development and Cancer. RUNX Proteins in Development and Cancer 299 320 .
Giselle Sek Suan Nah, Boon-Hui Tay, Sydney Brenner, Motomi Osato & Byrappa Venkatesh. (2014) Characterization of the Runx Gene Family in a Jawless Vertebrate, the Japanese Lamprey (Lethenteron japonicum). PLoS ONE 9:11, pages e113445.
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Feng Yue, Zhi Zhou, Lingling Wang, Rui Sun, Qiufen Jiang, Qilin Yi, Tao Zhang & Linsheng Song. (2014) The essential roles of core binding factors CfRunt and CfCBFβ in hemocyte production of scallop Chlamys farreri. Developmental & Comparative Immunology 44:2, pages 291-302.
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Kiho Lee, Jiwon Shim, Jihyun Lee & Junho Lee. (2013) Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans . G3 Genes|Genomes|Genetics 3:10, pages 1779-1784.
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Kiho Lee, Jiwon Shim, Jaebum Bae, Young-Joon Kim & Junho Lee. (2012) Stabilization of RNT-1 Protein, Runt-related Transcription Factor (RUNX) Protein Homolog of Caenorhabditis elegans, by Oxidative Stress through Mitogen-activated Protein Kinase Pathway. Journal of Biological Chemistry 287:13, pages 10444-10452.
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Sylvain Marcellini, Carola Bruna, Juan P Henr�quez, Miguel Albistur, Ariel E Reyes, Elias H Barriga, Berta Henr�quez & Mart�n Montecino. (2010) Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis. BMC Evolutionary Biology 10:1, pages 78.
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Michael Buchert, Charbel Darido, Ebba Lagerqvist, Anna Sedello, Chantal Cazevieille, Frank Buchholz, Jean–Francois Bourgaux, Julie Pannequin, Dominique Joubert & Frédéric Hollande. (2009) The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1. Gastroenterology 137:1, pages 156-164.e3.
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Elizabeth J Duncan, Megan J Wilson, James M Smith & Peter K Dearden. (2008) Evolutionary origin and genomic organisation of runt-domain containing genes in arthropods. BMC Genomics 9:1.
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Timothy D. Wiggin, Matthias Kretzler, Subramaniam Pennathur, Kelli A. Sullivan, Frank C. Brosius & Eva L. Feldman. (2008) Rosiglitazone Treatment Reduces Diabetic Neuropathy in Streptozotocin-Treated DBA/2J Mice. Endocrinology 149:10, pages 4928-4937.
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Xueni Li, Mei Huang, Huiling Zheng, Yinyin Wang, Fangli Ren, Yu Shang, Yonggong Zhai, David M. Irwin, Yuguang Shi, Di Chen & Zhijie Chang. (2008) CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation. Journal of Cell Biology 181:6, pages 959-972.
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Jochen Hecht, Sigmar Stricker, Ulrike Wiecha, Asita Stiege, Georgia Panopoulou, Lars Podsiadlowski, Albert J. Poustka, Christoph Dieterich, Siegfried Ehrich, Julia Suvorova, Stefan Mundlos & Volkhard Seitz. (2008) Evolution of a Core Gene Network for Skeletogenesis in Chordates. PLoS Genetics 4:3, pages e1000025.
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Jiwon Shim & Junho Lee. (2008) Regulation of rnt-1 expression mediated by the opposing effects of BRO-1 and DBL-1 in the nematode Caenorhabditis elegans. Biochemical and Biophysical Research Communications 367:1, pages 130-136.
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Dan Xia, Yuxia Zhang, Xinxin Huang, Yinyan Sun & Hong Zhang. (2007) The C. elegans CBFβ homolog, BRO-1, regulates the proliferation, differentiation and specification of the stem cell-like seam cell lineages. Developmental Biology 309:2, pages 259-272.
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Do Y Soung, Yufeng Dong, Yong Jun Wang, Michael J Zuscik, Edward M Schwarz, Regis J O'Keefe & Hicham Drissi. (2007) Runx3/AML2/Cbfa3 Regulates Early and Late Chondrocyte Differentiation. Journal of Bone and Mineral Research 22:8, pages 1260-1270.
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Jun Liang, Ling Yu, Jianghua Yin & Cathy Savage-Dunn. (2007) Transcriptional repressor and activator activities of SMA-9 contribute differentially to BMP-related signaling outputs. Developmental Biology 305:2, pages 714-725.
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Hiroshi Kagoshima, Katsuya Shigesada & Yuji Kohara. (2007) RUNX regulates stem cell proliferation and differentiation: Insights from studies ofC. elegans. Journal of Cellular Biochemistry 100:5, pages 1119-1130.
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Philip Y. Wai, Zhiyong Mi, Chengjiang Gao, Hongtao Guo, Carlos Marroquin & Paul C. Kuo. (2006) Ets-1 and Runx2 Regulate Transcription of a Metastatic Gene, Osteopontin, in Murine Colorectal Cancer Cells. Journal of Biological Chemistry 281:28, pages 18973-18982.
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Hiromitsu Yamamoto, Kosei Ito, Mariko Kawai, Yota Murakami, Kazuhisa Bessho & Yoshiaki Ito. (2006) Runx3 expression during mouse tongue and palate development. The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology 288A:7, pages 695-699.
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Tori C. Freitas & Prema Arasu. (2005) Cloning and characterisation of genes encoding two transforming growth factor-β-like ligands from the hookworm, Ancylostoma caninum. International Journal for Parasitology 35:14, pages 1477-1487.
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Yon Ju Ji, Gunasekaran Singaravelu & Joohong Ahnn. (2005) RNT-1 regulation inC. elegans. Journal of Cellular Biochemistry 96:1, pages 8-15.
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T. van der Meulen, S. Kranenbarg, H. Schipper, J. Samallo, J.L. van Leeuwen & H. Franssen. (2005) Identification and characterisation of two runx2 homologues in zebrafish with different expression patterns. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1729:2, pages 105-117.
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Nathan Smith, Yufeng Dong, Jane B. Lian, Jitesh Pratap, Paul D. Kingsley, Andre J. van Wijnen, Janet L. Stein, Edward M. Schwarz, Regis J. O'Keefe, Gary S. Stein & M. Hicham Drissi. (2005) Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. Journal of Cellular Physiology 203:1, pages 133-143.
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Yon-Ju Ji, Seunghee Nam, Yun-Hye Jin, Eun-Jung Cha, Kyeong-Sook Lee, Kyu-Yeong Choi, Hyun-Ok Song, Junho Lee, Suk-Chul Bae & Joohong Ahnn. (2004) RNT-1, the C. elegans homologue of mammalian RUNX transcription factors, regulates body size and male tail development. Developmental Biology 274:2, pages 402-412.
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Ja-Lok Ku, Sung-Bum Kang, Young-Kyoung Shin, Hio Chung Kang, Sung-Hye Hong, Il-Jin Kim, Joo-Ho Shin, Inn-Oc Han & Jae-Gahb Park. (2004) Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. Oncogene 23:40, pages 6736-6742.
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Junho Lee, Joohong Ahnn & Suk-Chul Bae. (2004) Homologs of RUNX and CBFβ/PEBP2β in C. elegans. Oncogene 23:24, pages 4346-4352.
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Jane B. Lian, Eva Balint, Amjad Javed, Hicham Drissi, Regan Vitti, Edward J. Quinlan, Lina Zhang, Andre J. van Wijnen, Janet L. Stein, Nancy Speck & Gary S. Stein. (2003) Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo. Journal of Cellular Physiology 196:2, pages 301-311.
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Suk Chul Bae & Yoshiaki Ito. (2003) Comment on Levanon et al ., ‘ Runx3 knockouts and stomach cancer’, in EMBO reports (June 2003) . EMBO reports 4:6, pages 538-539.
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Yoshiaki Ito & Kohei Miyazono. (2003) RUNX transcription factors as key targets of TGF-β superfamily signaling. Current Opinion in Genetics & Development 13:1, pages 43-47.
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Anthony J. Robertson, Carrie E. Dickey, John J. McCarthy & James A. Coffman. (2002) The expression of SpRunt during sea urchin embryogenesis. Mechanisms of Development 117:1-2, pages 327-330.
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Qing-Lin Li, Kosei Ito, Chohei Sakakura, Hiroshi Fukamachi, Ken-ichi Inoue, Xin-Zi Chi, Kwang-Youl Lee, Shintaro Nomura, Chang-Woo Lee, Sang-Bae Han, Hwan-Mook Kim, Wun-Jae Kim, Hiromitsu Yamamoto, Namiko Yamashita, Takashi Yano, Toshio Ikeda, Shigeyoshi Itohara, Johji Inazawa, Tatsuo Abe, Akeo Hagiwara, Hisakazu Yamagishi, Asako Ooe, Atsushi Kaneda, Takashi Sugimura, Toshikazu Ushijima, Suk-Chul Bae & Yoshiaki Ito. (2002) Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer. Cell 109:1, pages 113-124.
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