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Molecular and Cellular Biology Volume 22, 2002 - Issue 23
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Cell Growth and Development

Normal p53 Function in Primary Cells Deficient for Siah Genes

Ian J. Frew1 Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria3002
,
Ross A. Dickins1 Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria3002
,
Andrew R. Cuddihy1 Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria3002
,
Merci Del Rosario2 Chiron Corporation, 94608Emeryville, California
,
Christoph Reinhard2 Chiron Corporation, 94608Emeryville, California
,
Matthew J. O'Connell1 Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria3002;3 Department of Genetics
&
David D. L. Bowtell4 Department of Biochemistry, University of Melbourne, Parkville, Victoria3010, AustraliaCorrespondence[email protected]
 show all
Pages 8155-8164 | Received 19 Jun 2002, Accepted 06 Sep 2002, Published online: 28 Mar 2023

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M Gordian Adam, Sonja Matt, Sven Christian, Holger Hess-Stumpp, Andrea Haegebarth, Thomas G Hofmann & Carolyn Algire. (2015) SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle 14:23, pages 3734-3747.
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Ian J. Frew, Vicki E. Hammond, Ross A. Dickins, Julian M. W. Quinn, Carl R. Walkley, Natalie A. Sims, Ralf Schnall, Neil G. Della, Andrew J. Holloway, Matthew R. Digby, Peter W. Janes, David M. Tarlinton, Louise E. Purton, Matthew T. Gillespie & David D. L. Bowtell. (2003) Generation and Analysis of Siah2 Mutant Mice. Molecular and Cellular Biology 23:24, pages 9150-9161.
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Articles from other publishers (29)

James A. Conway, Grant Kinsman & Edgar R. Kramer. (2022) The Role of NEDD4 E3 Ubiquitin–Protein Ligases in Parkinson’s Disease. Genes 13:3, pages 513.
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Magdalena C Liebl, Jutta Moehlenbrink, Huong Becker, Günter Raddatz, Suhaib K Abdeen, Rami I Aqeilan, Frank Lyko & Thomas G Hofmann. (2021) DAZAP2 acts as specifier of the p53 response to DNA damage. Nucleic Acids Research 49:5, pages 2759-2776.
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Susan J. Burke, Jessica L. Taylor, Heidi M. Batdorf, Robert C. Noland, David H. Burk, Yongmei Yu, Z. Elizabeth Floyd & J. Jason Collier. (2020) The Ubiquitin Ligase SIAH2 Negatively Regulates Glucocorticoid Receptor Activity and Abundance. Biomedicines 9:1, pages 22.
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Ana Filipa Gonçalves, Mojca Adlesic, Simone Brandt, Tomas Hejhal, Sabine Harlander, Lukas Sommer, Olga Shakhova, Peter J. Wild & Ian J. Frew. (2017) Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nature Communications 8:1.
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L Das, S B Kokate, P Dixit, S Rath, N Rout, S P Singh, S E Crowe & A Bhattacharyya. (2017) Membrane-bound β-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. Oncogenesis 6:5, pages e327-e327.
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Jason P. DeBruyneJulie E. BaggsTrey K. Sato & John B. Hogenesch. (2015) Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock. Proceedings of the National Academy of Sciences 112:40, pages 12420-12425.
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Shirley K. Knauer, Nisintha Mahendrarajah, Wynand P. Roos & Oliver H. Krämer. (2015) The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers. Cytokine & Growth Factor Reviews 26:4, pages 405-413.
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SOONDUCK LEE, JINSUN KIM, SAMIL JUNG, CHENGPING LI, YOUNG YANG, KEUN IL KIM, JONG-SEOK LIM, YONGHWAN KIM, CHOONG-IL CHEON & MYEONG-SOK LEE. (2015) SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity. International Journal of Oncology 46:3, pages 1377-1384.
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Ian J. Frew, Zlatko Smole, Claudio R. Thoma & Wilhelm Krek. (2013) Genetic deletion of the long isoform of the von Hippel–Lindau tumour suppressor gene product alters microtubule dynamics. European Journal of Cancer 49:10, pages 2433-2440.
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Joachim Albers, Michal Rajski, Désirée Schönenberger, Sabine Harlander, Peter Schraml, Adriana von Teichman, Strahil Georgiev, Peter J. Wild, Holger Moch, Wilhelm Krek & Ian J. Frew. (2013) Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice . EMBO Molecular Medicine 5:6, pages 949-964.
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O H Krämer, R H Stauber, G Bug, J Hartkamp & S K Knauer. (2012) SIAH proteins: critical roles in leukemogenesis. Leukemia 27:4, pages 792-802.
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Mona Malz, Antje Aulmann, Jana Samarin, Michaela Bissinger, Thomas Longerich, Sabrina Schmitt, Peter Schirmacher & Kai Breuhahn. (2012) Nuclear accumulation of seven in absentia homologue-2 supports motility and proliferation of liver cancer cells. International Journal of Cancer 131:9, pages 2016-2026.
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Ronald T. K. Pang, Wei-Min Liu, Carmen O. N. Leung, Tian-Min Ye, Peter C. K. Kwan, Kai-Fai Lee & William S. B. Yeung. (2011) miR-135A Regulates Preimplantation Embryo Development through Down-Regulation of E3 Ubiquitin Ligase Seven in Absentia Homolog 1A (SIAH1A) Expression. PLoS ONE 6:11, pages e27878.
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Marzia Scortegagna, Tony Subtil, Jianfei Qi, Hyungsoo Kim, Wenhui Zhao, Wei Gu, Harriet Kluger & Ze'ev A. Ronai. (2011) USP13 Enzyme Regulates Siah2 Ligase Stability and Activity via Noncatalytic Ubiquitin-binding Domains. Journal of Biological Chemistry 286:31, pages 27333-27341.
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Kaori Fujita, Izumi Horikawa, Abdul M. Mondal, Lisa M. Miller Jenkins, Ettore Appella, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane & Curtis C. Harris. (2010) Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Nature Cell Biology 12:12, pages 1205-1212.
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Ingrid Cardenas, Robert E. Means, Paulomi Aldo, Kaori Koga, Sabine M. Lang, Carmen Booth, Alejandro Manzur, Enrique Oyarzun, Roberto Romero & Gil Mor. (2010) Viral Infection of the Placenta Leads to Fetal Inflammation and Sensitization to Bacterial Products Predisposing to Preterm Labor. The Journal of Immunology 185:2, pages 1248-1257.
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Jean-François Millau, Sabine Mai, Nathalie Bastien & Régen Drouin. (2010) p53 functions and cell lines: Have we learned the lessons from the past?. BioEssays 32:5, pages 392-400.
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Colin M. House, Andreas Möller & David D.L. Bowtell. (2009) Siah Proteins: Novel Drug Targets in the Ras and Hypoxia Pathways. Cancer Research 69:23, pages 8835-8838.
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Reiko Ban, Hideki Matsuzaki, Tomohiro Akashi, Gyosuke Sakashita, Hisaaki Taniguchi, Sam-Yong Park, Hirofumi Tanaka, Koichi Furukawa & Takeshi Urano. (2009) Mitotic Regulation of the Stability of Microtubule Plus-end Tracking Protein EB3 by Ubiquitin Ligase SIAH-1 and Aurora Mitotic Kinases. Journal of Biological Chemistry 284:41, pages 28367-28381.
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Sanguk Yun, Andreas Möller, Suhn-Kee Chae, Won-Pyo Hong, Young Ju Bae, David D.L. Bowtell, Sung Ho Ryu & Pann-Ghill Suh. (2008) Siah Proteins Induce the Epidermal Growth Factor-dependent Degradation of Phospholipase Cϵ. Journal of Biological Chemistry 283:2, pages 1034-1042.
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Sarah E. Cooper. (2007) In vivo function of a novel Siah protein in Drosophila. Mechanisms of Development 124:7-8, pages 584-591.
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Zhiheng Xu, Andrew Sproul, Wenyi Wang, Nikolay Kukekov & Lloyd A. Greene. (2006) Siah1 Interacts with the Scaffold Protein POSH to Promote JNK Activation and Apoptosis. Journal of Biological Chemistry 281:1, pages 303-312.
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Julian P. Venables, Caroline Dalgliesh, Maria Paolo Paronetto, Lindi Skitt, Jared K. Thornton, Philippa T. Saunders, Claudio Sette, Keith T. Jones & David J. Elliott. (2004) SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome. Human Molecular Genetics 13:14, pages 1525-1534.
Crossref
Ian J. Frew, Natalie A. Sims, Julian M.W. Quinn, Carl R. Walkley, Louise E. Purton, David D.L. Bowtell & Matthew T. Gillespie. (2004) Osteopenia in Siah1a Mutant Mice. Journal of Biological Chemistry 279:28, pages 29583-29588.
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Yun-Cai Liu. (2004) Ubiquitin Ligases and the Immune Response. Annual Review of Immunology 22:1, pages 81-127.
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Giusy FiucciSéverine BeaucourtDominique DuflautAlexandra LespagnolPamela Stumptner-CuveletteAnne GéantGilles BuchwalterMarcel TuynderLaurent SusiniJean-Michel LassalleChristine WasylykBohdan WasylykMoshe OrenRobert AmsonAdam Telerman. (2004) Siah-1b is a direct transcriptional target of p53: Identification of the functional p53 responsive element in the siah-1b promoter. Proceedings of the National Academy of Sciences 101:10, pages 3510-3515.
Crossref
Lilia Topol, Xueyuan Jiang, Hosoon Choi, Lisa Garrett-Beal, Peter J. Carolan & Yingzi Yang. (2003) Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation. Journal of Cell Biology 162:5, pages 899-908.
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Tomoshige Kino, Emanuel Souvatzoglou, Massimo U. De Martino, Maria Tsopanomihalu, Yihong Wan & George P. Chrousos. (2003) Protein 14-3-3σ Interacts with and Favors Cytoplasmic Subcellular Localization of the Glucocorticoid Receptor, Acting as a Negative Regulator of the Glucocorticoid Signaling Pathway. Journal of Biological Chemistry 278:28, pages 25651-25656.
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. (2003) Anti-Aging Medicine LiteratureWatch. Journal of Anti-Aging Medicine 6:1, pages 45-64.
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