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Mammalian Genetic Models with Minimal or Complex Phenotypes

Loss of Bard1, the Heterodimeric Partner of the Brca1 Tumor Suppressor, Results in Early Embryonic Lethality and Chromosomal Instability

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Pages 5056-5063 | Received 18 Dec 2002, Accepted 28 Apr 2003, Published online: 27 Mar 2023

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Ming Ren Toh, Siao Ting Chong, Sock Hoai Chan, Chen Ee Low, Nur Diana Binte Ishak, Jing Quan Lim, Eliza Courtney & Joanne Ngeow. (2019) Functional analysis of clinical BARD1 germline variants . Molecular Case Studies 5:4, pages a004093.
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Weixing ZhaoClaudia Wiese, Youngho KwonRobert Hromas & Patrick Sung. (2019) The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination. Annual Review of Biochemistry 88:1, pages 221-245.
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J. Brooks CrickardEric C. Greene. (2019) Helicase Mechanisms During Homologous Recombination in Saccharomyces cerevisiae . Annual Review of Biophysics 48:1, pages 255-273.
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Aleksandra I. Adamovich, Tapahsama Banerjee, Margaret Wingo, Kathryn Duncan, Jie Ning, Fernanda Martins Rodrigues, Kuan-lin Huang, Cindy Lee, Feng Chen, Li Ding & Jeffrey D. Parvin. (2019) Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity. PLOS Genetics 15:3, pages e1008049.
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Yihan Peng, Qingchao Liao, Wei Tan, Changmin Peng, Zhaohua Hu, Yali Chen, Zhuqing Li, Jing Li, Bei Zhen, Wenge Zhu, Xiangpan Li, Yi Yao, Qibin Song, Chengsheng Liu, Xiangdong Qi, Fuchu He & Huadong Pei. (2019) The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors. Nature Communications 10:1.
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Crossref
Qianyan Li, Takamune T. Saito, Marina Martinez-Garcia, Alison J. Deshong, Saravanapriah Nadarajan, Katherine S. Lawrence, Paula M. Checchi, Monica P. Colaiacovo & JoAnne Engebrecht. (2018) The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans. PLOS Genetics 14:11, pages e1007701.
Crossref
Eva Janisiw, Maria Rosaria Dello Stritto, Verena Jantsch & Nicola Silva. (2018) BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis. PLOS Genetics 14:11, pages e1007653.
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David Billing, Michiko Horiguchi, Foon Wu-Baer, Angelo Taglialatela, Giuseppe Leuzzi, Silvia Alvarez Nanez, Wenxia Jiang, Shan Zha, Matthias Szabolcs, Chyuan-Sheng Lin, Alberto Ciccia & Richard Baer. (2018) The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection. Molecular Cell 72:1, pages 127-139.e8.
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Chun-Chin Chen, Weiran Feng, Pei Xin LimElizabeth M. KassMaria Jasin. (2018) Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer. Annual Review of Cancer Biology 2:1, pages 313-336.
Crossref
Flora Cimmino, Daniela Formicola & Mario Capasso. (2017) Dualistic Role of BARD1 in Cancer. Genes 8:12, pages 375.
Crossref
Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries & Alfred C. O. Vertegaal. (2017) The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. Nature Communications 8:1.
Crossref
Weixing Zhao, Justin B. Steinfeld, Fengshan Liang, Xiaoyong Chen, David G. Maranon, Chu Jian Ma, Youngho Kwon, Timsi Rao, Weibin Wang, Chen Sheng, Xuemei Song, Yanhong Deng, Judit Jimenez-Sainz, Lucy Lu, Ryan B. Jensen, Yong Xiong, Gary M. Kupfer, Claudia Wiese, Eric C. Greene & Patrick Sung. (2017) BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing. Nature 550:7676, pages 360-365.
Crossref
Peter L. Chang, Emily Kopania, Sara Keeble, Brice A. J. Sarver, Erica Larson, Annie Orth, Khalid Belkhir, Pierre Boursot, François Bonhomme, Jeffrey M. Good & Matthew D. Dean. (2017) Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype. Mammalian Genome 28:9-10, pages 416-425.
Crossref
Lisa Dwane, William M. Gallagher, Tríona Ní Chonghaile & Darran P. O'Connor. (2017) The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways. Journal of Biological Chemistry 292:9, pages 3543-3551.
Crossref
Maxim Pilyugin, Pierre-Alain André, Magdalena Ratajska, Alina Kuzniacka, Janusz Limon, Benjamin B. Tournier, Julien Colas, Geoff Laurent & Irmgard Irminger-Finger. (2016) Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability. Oncotarget 8:6, pages 9339-9353.
Crossref
Wen Fu, Jinhong Zhu, Si-Wei Xiong, Wei Jia, Zhang Zhao, Shi-Bo Zhu, Jin-Hua Hu, Feng-Hua Wang, Huimin Xia, Jing He & Guo-Chang Liu. (2017) BARD1 Gene Polymorphisms Confer Nephroblastoma Susceptibility. EBioMedicine 16, pages 101-105.
Crossref
Irmgard Irminger-Finger. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer 428 432 .
Kamila A. Marzec, Estefania Martino-Echarri, Irmgard Irminger-Finger & Beric R. Henderson. (2016) BARD1 splice variants display mislocalization in breast cancer cells and can alter the apoptotic response to cisplatin. Cancer Letters 381:1, pages 149-155.
Crossref
Colleen R. Reczek, Reena Shakya, Yana Miteva, Matthias Szabolcs, Thomas Ludwig & Richard Baer. (2016) The DNA resection protein CtIP promotes mammary tumorigenesis. Oncotarget 7:22, pages 32172-32183.
Crossref
Ozkan Ozden, Faraz Bishehsari, Jessica Bauer, Seong-Hoon Park, Arundhati Jana, Seung Hyun Baik, Judith C. Sporn, Jonas J. Staudacher, Cemal Yazici, Nancy Krett & Barbara Jung. (2016) Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer. Scientific Reports 6:1.
Crossref
Irmgard Irminger-Finger, Magda Ratajska & Maxim Pilyugin. (2016) New concepts on BARD1: Regulator of BRCA pathways and beyond. The International Journal of Biochemistry & Cell Biology 72, pages 1-17.
Crossref
Cindy Lee, Tapahsama Banerjee, Jessica Gillespie, Amanda Ceravolo, Matthew R. Parvinsmith, Lea M. Starita, Stanley Fields, Amanda E. Toland & Jeffrey D. Parvin. (2015) Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks. Human Mutation 36:12, pages 1205-1214.
Crossref
MAGDALENA RATAJSKA, MAGDALENA MATUSIAK, ALINA KUZNIACKA, BARTOSZ WASAG, IZABELA BROZEK, WOJCIECH BIERNAT, MAGDALENA KOCZKOWSKA, JAROSLAW DEBNIAK, MARCIN SNIADECKI, PIOTR KOZLOWSKI, KATARZYNA KLONOWSKA, MAXIM PILYUGIN, DARIUSZ WYDRA, GEOFF LAURENT, JANUSZ LIMON & IRMGARD IRMINGER-FINGER. (2015) Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms. Oncology Reports 34:5, pages 2609-2617.
Crossref
Varsha Tembe, Estefania Martino-Echarri, Kamila A. Marzec, Myth T.S. Mok, Kirsty M. Brodie, Kate Mills, Ying Lei, Anna DeFazio, Helen Rizos, Emma Kettle, Ross Boadle & Beric R. Henderson. (2015) The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function. Cellular Signalling 27:9, pages 1763-1771.
Crossref
J Chen & W A Weiss. (2014) Alternative splicing in cancer: implications for biology and therapy. Oncogene 34:1, pages 1-14.
Crossref
Julia Specks, Maria Nieto-Soler, Andres J. Lopez-Contreras & Oscar Fernandez-Capetillo. 2015. Mouse Models of Cancer. Mouse Models of Cancer 413 437 .
Maxim Pilyugin & Irmgard Irminger-Finger. (2014) Long non-coding RNA and microRNAs might act in regulating the expression of BARD1 mRNAs. The International Journal of Biochemistry & Cell Biology 54, pages 356-367.
Crossref
Irmgard Irminger-Finger. 2016. Encyclopedia of Cancer. Encyclopedia of Cancer 1 5 .
S. De Summa, R. Pinto, D. Sambiasi, D. Petriella, V. Paradiso, A. Paradiso & S. Tommasi. (2013) BRCAness: a deeper insight into basal-like breast tumors. Annals of Oncology 24, pages viii13-viii21.
Crossref
Mischa L. Li & Roger A. Greenberg. (2012) Links between genome integrity and BRCA1 tumor suppression. Trends in Biochemical Sciences 37:10, pages 418-424.
Crossref
Shane R. Stecklein, Easwari Kumaraswamy, Fariba Behbod, Wenjia Wang, Vamsee Chaguturu, Lisa M. Harlan-Williams & Roy A. Jensen. (2012) BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. Proceedings of the National Academy of Sciences 109:34, pages 13650-13655.
Crossref
Magdalena Ratajska, Ewelina Antoszewska, Anna Piskorz, Izabela Brozek, Åke Borg, Hanna Kusmierek, Wojciech Biernat & Janusz Limon. (2011) Cancer predisposing BARD1 mutations in breast–ovarian cancer families. Breast Cancer Research and Treatment 131:1, pages 89-97.
Crossref
Irmgard Irminger-Finger. 2011. Encyclopedia of Cancer. Encyclopedia of Cancer 339 342 .
Renaud Sabatier, José Adélaïde, Pascal Finetti, Anthony Ferrari, Laetitia Huiart, Hagay Sobol, Max Chaffanet, Daniel Birnbaum & François Bertucci. (2010) BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal breast cancer. Genes, Chromosomes and Cancer 49:12, pages 1143-1151.
Crossref
Angelos Thanassoulas, Michail Nomikos, Maria Theodoridou, Drakoulis Yannoukakos, Dimitris Mastellos & George Nounesis. (2010) Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1804:9, pages 1908-1916.
Crossref
Ann A. Kiessling, Ritsa Bletsa, Bryan Desmarais, Christina Mara, Kostas Kallianidis & Dimitris Loutradis. (2010) Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints. Journal of Assisted Reproduction and Genetics 27:6, pages 265-276.
Crossref
Conleth G. Murphy & Mary Ellen Moynahan. (2010) BRCA Gene Structure and Function in Tumor Suppression. The Cancer Journal 16:1, pages 39-47.
Crossref
Sharon E. Johnatty, Jonathan Beesley, Xiaoqing Chen, John L. Hopper, Melissa C. Southey, Graham G. Giles, David E. Goldgar, Georgia Chenevix-Trench & Amanda B. Spurdle. (2008) The BARD1 Cys557Ser polymorphism and breast cancer risk: an Australian case–control and family analysis. Breast Cancer Research and Treatment 115:1, pages 145-150.
Crossref
Stephan Ryser, Eva Dizin, Charles Edward Jefford, Bénédicte Delaval, Sarantis Gagos, Agni Christodoulidou, Karl-Heinz Krause, Daniel Birnbaum & Irmgard Irminger-Finger. (2009) Distinct Roles of BARD1 Isoforms in Mitosis: Full-Length BARD1 Mediates Aurora B Degradation, Cancer-Associated BARD1β Scaffolds Aurora B and BRCA2. Cancer Research 69:3, pages 1125-1134.
Crossref
Hiroyuki Nishikawa, Wenwen Wu, Ayaka Koike, Ryoko Kojima, Hiromichi Gomi, Mamoru Fukuda & Tomohiko Ohta. (2009) BRCA1-Associated Protein 1 Interferes with BRCA1/BARD1 RING Heterodimer Activity. Cancer Research 69:1, pages 111-119.
Crossref
Katherine L. Nathanson. 2010. The Role of Genetics in Breast and Reproductive Cancers. The Role of Genetics in Breast and Reproductive Cancers 131 162 .
Ellen Solomon & Joanna R. Morris. 2010. The Role of Genetics in Breast and Reproductive Cancers. The Role of Genetics in Breast and Reproductive Cancers 75 92 .
Latarsha J. Reid, Reena Shakya, Ami P. Modi, Maria Lokshin, Jiin-Tsuey Cheng, Maria Jasin, Richard BaerThomas Ludwig. (2008) E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proceedings of the National Academy of Sciences 105:52, pages 20876-20881.
Crossref
John D. Gordan, Priti Lal, Vijay R. Dondeti, Richard Letrero, Krishna N. Parekh, C. Elisa Oquendo, Roger A. Greenberg, Keith T. Flaherty, W. Kimryn Rathmell, Brian Keith, M. Celeste Simon & Katherine L. Nathanson. (2008) HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma. Cancer Cell 14:6, pages 435-446.
Crossref
Roger A. Greenberg. (2008) Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network. Chromosoma 117:4, pages 305-317.
Crossref
Reena Shakya, Matthias Szabolcs, Ellen McCarthy, Elson Ospina, Katia Basso, Subhadra Nandula, Vundavalli Murty, Richard Baer & Thomas Ludwig. (2008) The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression . Proceedings of the National Academy of Sciences 105:19, pages 7040-7045.
Crossref
Irmgard Irminger-Finger & Shazib Pervais. 2008. Oxidants in Biology. Oxidants in Biology 293 301 .
Lin Li, Stephan Ryser, Eva Dizin, Dietmar Pils, Michael Krainer, Charles Edward Jefford, Francesco Bertoni, Robert Zeillinger & Irmgard Irminger-Finger. (2007) Oncogenic BARD1 Isoforms Expressed in Gynecological Cancers. Cancer Research 67:24, pages 11876-11885.
Crossref
Marsha Laufer, Subhadra V. Nandula, Ami P. Modi, Shuang Wang, Maria Jasin, Vundavalli V. V.S. Murty, Thomas Ludwig & Richard Baer. (2007) Structural Requirements for the BARD1 Tumor Suppressor in Chromosomal Stability and Homology-directed DNA Repair. Journal of Biological Chemistry 282:47, pages 34325-34333.
Crossref
Sarantis Gagos. 2005. The Cancer Handbook. The Cancer Handbook.
Varsha Tembe & Beric R. Henderson. (2007) BARD1 Translocation to Mitochondria Correlates with Bax Oligomerization, Loss of Mitochondrial Membrane Potential, and Apoptosis. Journal of Biological Chemistry 282:28, pages 20513-20522.
Crossref
Lin Li, Marie Cohen, JianYu Wu, Mamadou Hady Sow, Branka Nikolic, Paul Bischof & Irmgard Irminger-Finger. (2007) Identification of BARD1 splice-isoforms involved in human trophoblast invasion. The International Journal of Biochemistry & Cell Biology 39:9, pages 1659-1672.
Crossref
Vladimir Joukov, Aaron C. Groen, Tatyana Prokhorova, Ruth Gerson, Erinn White, Alison Rodriguez, Johannes C. Walter & David M. Livingston. (2006) The BRCA1/BARD1 Heterodimer Modulates Ran-Dependent Mitotic Spindle Assembly. Cell 127:3, pages 539-552.
Crossref
S.J. Boulton. (2006) Cellular functions of the BRCA tumour-suppressor proteins. Biochemical Society Transactions 34:5, pages 633-645.
Crossref
K Gudmundsdottir & A Ashworth. (2006) The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene 25:43, pages 5864-5874.
Crossref
Wim Reidt, Rebecca Wurz, Kristina Wanieck, Hoang Ha Chu & Holger Puchta. (2006) A homologue of the breast cancer-associated gene BARD1 is involved in DNA repair in plants. The EMBO Journal 25:18, pages 4326-4337.
Crossref
Jing-Ruey J. YehRong JuCathleen M. BrdlikWenjun ZhangYi ZhangMary E. MatyskielaJoseph D. ShotwellCraig M. Crews. (2006) Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest. Proceedings of the National Academy of Sciences 103:27, pages 10379-10384.
Crossref
Simon N Stacey, Patrick Sulem, Oskar T Johannsson, Agnar Helgason, Julius Gudmundsson, Jelena P Kostic, Kristleifur Kristjansson, Thora Jonsdottir, Helgi Sigurdsson, Jon Hrafnkelsson, Jakob Johannsson, Thorarinn Sveinsson, Gardar Myrdal, Hlynur Niels Grimsson, Jon T Bergthorsson, Laufey T Amundadottir, Jeffrey R Gulcher, Unnur Thorsteinsdottir, Augustine Kong & Kari Stefansson. (2006) The BARD1 Cys557Ser Variant and Breast Cancer Risk in Iceland. PLoS Medicine 3:7, pages e217.
Crossref
Irmgard Irminger-Finger & Charles Edward Jefford. (2006) Is there more to BARD1 than BRCA1?. Nature Reviews Cancer 6:5, pages 382-391.
Crossref
Jian-Yu Wu, Anne-Therese Vlastos, Marie-Françoise Pelte, Maria-Adelaide Caligo, Andrea Bianco, Karl-Heinz Krause, Geoffrey J. Laurent & Irmgard Irminger-Finger. (2006) Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosis. International Journal of Cancer 118:5, pages 1215-1226.
Crossref
Amanda M. Simons, Andrew A. Horwitz, Lea M. Starita, Karen Griffin, R. Scott Williams, J.N. Mark Glover & Jeffrey D. Parvin. (2006) BRCA1 DNA-Binding Activity Is Stimulated by BARD1. Cancer Research 66:4, pages 2012-2018.
Crossref
Errol C. Friedberg & Lisiane B. Meira. (2006) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. DNA Repair 5:2, pages 189-209.
Crossref
Makiko Tsuzuki, Wenwen Wu, Hiroyuki Nishikawa, Ryosuke Hayami, Daisuke Oyake, Yukari Yabuki, Mamoru Fukuda & Tomohiko Ohta. (2006) A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats. Cancer Letters 233:1, pages 108-116.
Crossref
Yanfen Hu, Sagar Ghosh, Asma Amleh, Wei Yue, Yunzhe Lu, Adam Katz & Rong Li. (2005) Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression. Oncogene 24:56, pages 8343-8348.
Crossref
J. Valentin. (2016) Chapters 6 and 7. Annals of the ICRP 35:4, pages 93-140.
Crossref
J. Valentin. (2016) Chapter 3. Annals of the ICRP 35:4, pages 41-60.
Crossref
Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz & Tom Ellenberger. 2005. DNA Repair and Mutagenesis. DNA Repair and Mutagenesis 663 710 .
Beric R. Henderson. (2005) Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking. BioEssays 27:9, pages 884-893.
Crossref
Atish D. Choudhury, Hong Xu, Ami P. Modi, Wenzhu Zhang, Thomas Ludwig & Richard Baer. (2005) Hyperphosphorylation of the BARD1 Tumor Suppressor in Mitotic Cells. Journal of Biological Chemistry 280:26, pages 24669-24679.
Crossref
Anis Feki, Charles Edward Jefford, Philip Berardi, Jian-Yu Wu, Laetitia Cartier, Karl-Heinz Krause & Irmgard Irminger-Finger. (2005) BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase. Oncogene 24:23, pages 3726-3736.
Crossref
Sarantis Gagos & Irmgard Irminger-Finger. (2005) Chromosome instability in neoplasia: chaotic roots to continuous growth. The International Journal of Biochemistry & Cell Biology 37:5, pages 1014-1033.
Crossref
Stefan Schüchner, Varsha Tembe, José A. Rodriguez & Beric R. Henderson. (2005) Nuclear Targeting and Cell Cycle Regulatory Function of Human BARD1. Journal of Biological Chemistry 280:10, pages 8855-8861.
Crossref
Susanne M. Gollin. (2005) Mechanisms leading to chromosomal instability. Seminars in Cancer Biology 15:1, pages 33-42.
Crossref
Charles Edward Jefford, Jian Yu Wu & Irmgard Irminger-Finger. 2005. Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma. Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma 33 43 .
Errol C. Friedberg & Lisiane B. Meira. (2004) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6). DNA Repair 3:12, pages 1617-1638.
Crossref
Atish D. Choudhury, Hong Xu & Richard Baer. (2004) Ubiquitination and Proteasomal Degradation of the BRCA1 Tumor Suppressor Is Regulated during Cell Cycle Progression. Journal of Biological Chemistry 279:32, pages 33909-33918.
Crossref
Megan Fabbro, Stefan Schuechner, Wendy W.Y Au & Beric R Henderson. (2004) BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention. Experimental Cell Research 298:2, pages 661-673.
Crossref
Joanna R. Morris & Ellen Solomon. (2004) BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair. Human Molecular Genetics 13:8, pages 807-817.
Crossref
Tomohiko Ohta & Mamoru Fukuda. (2004) Ubiquitin and breast cancer. Oncogene 23:11, pages 2079-2088.
Crossref
José Antonio Rodriguez, Stefan Schüchner, Wendy W Y Au, Megan Fabbro & Beric R Henderson. (2003) Nuclear–cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1. Oncogene 23:10, pages 1809-1820.
Crossref
Foon Wu-Baer, Karen Lagrazon, Wei Yuan & Richard Baer. (2003) The BRCA1/BARD1 Heterodimer Assembles Polyubiquitin Chains through an Unconventional Linkage Involving Lysine Residue K6 of Ubiquitin. Journal of Biological Chemistry 278:37, pages 34743-34746.
Crossref

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