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Transcriptional Regulation

Structural Environment Dictates the Biological Significance of Heme-Responsive Motifs and the Role of Hsp90 in the Activation of the Heme Activator Protein Hap1

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Pages 5857-5866 | Received 21 Feb 2003, Accepted 19 May 2003, Published online: 27 Mar 2023

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Kazuhiko Igarashi & Miki Watanabe-Matsui. (2014) Wearing Red for Signaling: The Heme-Bach Axis in Heme Metabolism, Oxidative Stress Response and Iron Immunology. The Tohoku Journal of Experimental Medicine 232:4, pages 229-253.
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Anders M. Näär & Jitendra K. Thakur. (2009) Nuclear receptor-like transcription factors in fungi. Genes & Development 23:4, pages 419-432.
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Patrice Hamel, Vincent Corvest, Philippe Giegé & Géraldine Bonnard. (2009) Biochemical requirements for the maturation of mitochondrial c-type cytochromes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1793:1, pages 125-138.
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Martin J. Warren & Alison G. SmithAnn Smith. 2009. Tetrapyrroles. Tetrapyrroles 184 207 .
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Mónica Lamas-Maceiras, Laura Núñez, Esther Rodríguez-Belmonte, María Isabel González-Siso & María Esperanza Cerdán. (2007) Functional characterization of KlHAP1: A model to foresee different mechanisms of transcriptional regulation by Hap1p in yeasts. Gene 405:1-2, pages 96-107.
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Xiantong Xin, Changgui Lan, Hee Chul Lee & Li Zhang. (2007) Regulation of the HAP1 gene involves positive actions of histone deacetylases. Biochemical and Biophysical Research Communications 362:1, pages 120-125.
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Li Yi & Stephen W. Ragsdale. (2007) Evidence That the Heme Regulatory Motifs in Heme Oxygenase-2 Serve as a Thiol/Disulfide Redox Switch Regulating Heme Binding. Journal of Biological Chemistry 282:29, pages 21056-21067.
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Sarah M Mense & Li Zhang. (2006) Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases. Cell Research 16:8, pages 681-692.
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Kazuhiko IgarashiJiying Sun. (2006) The Heme-Bach1 Pathway in the Regulation of Oxidative Stress Response and Erythroid Differentiation. Antioxidants & Redox Signaling 8:1-2, pages 107-118.
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Thomas Hon, Hee Chul Lee, Zhanzhi Hu, Vishwanath R Iyer & Li Zhang. (2005) The Heme Activator Protein Hap1 Represses Transcription by a Heme-Independent Mechanism in Saccharomyces cerevisiae. Genetics 169:3, pages 1343-1352.
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Jianhua Yang, Koichiro Ishimori & Mark R. O'Brian. (2005) Two Heme Binding Sites Are Involved in the Regulated Degradation of the Bacterial Iron Response Regulator (Irr) Protein. Journal of Biological Chemistry 280:9, pages 7671-7676.
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Changgui Lan, Hee Chul Lee, Shan Tang & Li Zhang. (2004) A Novel Mode of Chaperone Action. Journal of Biological Chemistry 279:26, pages 27607-27612.
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Thomas Hon, Athena Dodd, Reinhard Dirmeier, Nadia Gorman, Peter R. Sinclair, Li Zhang & Robert O. Poyton. (2003) A Mechanism of Oxygen Sensing in Yeast. Journal of Biological Chemistry 278:50, pages 50771-50780.
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