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Cell and Organelle Structure and Assembly

Adhesive and Lateral E-Cadherin Dimers Are Mediated by the Same Interface

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Pages 7965-7972 | Received 28 Apr 2003, Accepted 04 Aug 2003, Published online: 27 Mar 2023

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Romain Levayer. (2012) Régulation de l’adhérence intercellulaire pendant la morphogenèse épithéliale. Biologie Aujourd'hui 206:3, pages 219-236.
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S. Yamada, A. Cheung, T.N. Nguyen & W. Shih. 2012. Comprehensive Biophysics. Comprehensive Biophysics 33 47 .
Sergey Troyanovsky. 2012. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease 89 108 .
Deborah Leckband & Sanjeevi Sivasankar. 2012. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease 63 88 .
Noboru Ishiyama & Mitsuhiko Ikura. 2012. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease. Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease 39 62 .
Sally A. Kim, Chin-Yin Tai, Lee-Peng Mok, Eric A. Mosser & Erin M. Schuman. (2011) Calcium-dependent dynamics of cadherin interactions at cell–cell junctions. Proceedings of the National Academy of Sciences 108:24, pages 9857-9862.
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Soonjin Hong, Regina B. Troyanovsky & Sergey M. Troyanovsky. (2011) Cadherin exits the junction by switching its adhesive bond. Journal of Cell Biology 192:6, pages 1073-1083.
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Quanming Shi, Venkat Maruthamuthu, Fang Li & Deborah Leckband. (2010) Allosteric Cross Talk between Cadherin Extracellular Domains. Biophysical Journal 99:1, pages 95-104.
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Rudolfs Zalups & James KoropatnickAlan Parrish & Walter Prozialeck. 2010. Cellular and Molecular Biology of Metals. Cellular and Molecular Biology of Metals 327 350 .
Gethin R. Owen & David L. Stokes. (2010) Exploring the Nature of Desmosomal Cadherin Associations in 3D. Dermatology Research and Practice 2010, pages 1-12.
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Crossref
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Glen S. Marrs, Christopher S. Theisen & Juan L. Brusés. (2009) N-cadherin modulates voltage activated calcium influx via RhoA, p120-catenin, and myosin–actin interaction. Molecular and Cellular Neuroscience 40:3, pages 390-400.
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Yunxiang ZhangSanjeevi Sivasankar, W. James NelsonSteven Chu. (2009) Resolving cadherin interactions and binding cooperativity at the single-molecule level. Proceedings of the National Academy of Sciences 106:1, pages 109-114.
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Alexi Kiss, Regina B. Troyanovsky & Sergey M. Troyanovsky. (2008) p120-Catenin Is a Key Component of the Cadherin–γ-Secretase Supercomplex. Molecular Biology of the Cell 19:10, pages 4042-4050.
Crossref
Olivier Thoumine, Helge Ewers, Martin Heine, Laurent Groc, Renato Frischknecht, Grégory Giannone, Christel Poujol, Philippe Legros, Brahim Lounis, Laurent Cognet & Daniel Choquet. (2008) Probing the Dynamics of Protein–Protein Interactions at Neuronal Contacts by Optical Imaging. Chemical Reviews 108:5, pages 1565-1587.
Crossref
Shoshana Posy, Lawrence Shapiro & Barry Honig. (2008) Sequence and Structural Determinants of Strand Swapping in Cadherin Domains: Do All Cadherins Bind Through the Same Adhesive Interface?. Journal of Molecular Biology 378:4, pages 954-968.
Crossref
Aneeza Salim & Lee Ratner. (2008) Modulation of β-Catenin and E-Cadherin Interaction by Vpu Increases Human Immunodeficiency Virus Type 1 Particle Release. Journal of Virology 82:8, pages 3932-3938.
Crossref
Carien M. Niessen & Cara J. Gottardi. (2008) Molecular components of the adherens junction. Biochimica et Biophysica Acta (BBA) - Biomembranes 1778:3, pages 562-571.
Crossref
Marc P. Stemmler. (2008) Cadherins in development and cancer. Molecular BioSystems 4:8, pages 835.
Crossref
Sabine PokuttaWilliam I. Weis. (2007) Structure and Mechanism of Cadherins and Catenins in Cell-Cell Contacts. Annual Review of Cell and Developmental Biology 23:1, pages 237-261.
Crossref
Regina B. TroyanovskyOscar Laur & Sergey M. Troyanovsky. (2007) Stable and Unstable Cadherin Dimers: Mechanisms of Formation and Roles in Cell Adhesion. Molecular Biology of the Cell 18:11, pages 4343-4352.
Crossref
Hitomi Tsuiji, Liang Xu, Kathleen Schwartz & Barry M. Gumbiner. (2007) Cadherin Conformations Associated with Dimerization and Adhesion. Journal of Biological Chemistry 282:17, pages 12871-12882.
Crossref
Lisa-Marie Munter, Philipp Voigt, Anja Harmeier, Daniela Kaden, Kay E Gottschalk, Christoph Weise, Rüdiger Pipkorn, Michael Schaefer, Dieter Langosch & Gerd Multhaup. (2007) GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42. The EMBO Journal 26:6, pages 1702-1712.
Crossref
Deborah LeckbandAnil Prakasam. (2006) MECHANISM AND DYNAMICS OF CADHERIN ADHESION. Annual Review of Biomedical Engineering 8:1, pages 259-287.
Crossref
Regina B. Troyanovsky, Eugene P. Sokolov & Sergey M. Troyanovsky. (2006) Endocytosis of Cadherin from Intracellular Junctions Is the Driving Force for Cadherin Adhesive Dimer Disassembly. Molecular Biology of the Cell 17:8, pages 3484-3493.
Crossref
Saurabh D. Patel, Carlo Ciatto, Chien Peter Chen, Fabiana Bahna, Manisha Rajebhosale, Natalie Arkus, Ira Schieren, Thomas M. Jessell, Barry Honig, Stephen R. Price & Lawrence Shapiro. (2006) Type II Cadherin Ectodomain Structures: Implications for Classical Cadherin Specificity. Cell 124:6, pages 1255-1268.
Crossref
Olivier Thoumine, Mireille Lambert, René-Marc Mège & Daniel Choquet. (2006) Regulation of N-Cadherin Dynamics at Neuronal Contacts by Ligand Binding and Cytoskeletal Coupling. Molecular Biology of the Cell 17:2, pages 862-875.
Crossref
Yeh-Shiu Chu, Olivier Eder, William A. Thomas, Inbal Simcha, Frederic Pincet, Avri Ben-Ze'ev, Eric Perez, Jean Paul Thiery & Sylvie Dufour. (2006) Prototypical Type I E-cadherin and Type II Cadherin-7 Mediate Very Distinct Adhesiveness through Their Extracellular Domains. Journal of Biological Chemistry 281:5, pages 2901-2910.
Crossref
David R. Garrod, Mohamed Y. Berika, William F. Bardsley, David Holmes & Lydia Tabernero. (2005) Hyper-adhesion in desmosomes: its regulation in wound healing and possible relationship to cadherin crystal structure. Journal of Cell Science 118:24, pages 5743-5754.
Crossref
Sergey Troyanovsky. (2005) Cadherin dimers in cell–cell adhesion. European Journal of Cell Biology 84:2-3, pages 225-233.
Crossref
Oliver J. Harrison, Elaine M. Corps, Torunn Berge & Peter J. Kilshaw. (2005) The mechanism of cell adhesion by classical cadherins: the role of domain 1. Journal of Cell Science 118:4, pages 711-721.
Crossref
A. W. Koch, K. L. Manzur & W. Shan. (2016) Structure-based models of cadherin-mediated cell adhesion: the evolution continues. Cellular and Molecular Life Sciences 61:15, pages 1884-1895.
Crossref
Rana Al-Kurdi, Danielle Gulino-Debrac, Laurence Martel, Jean-François Legrand, Anne Renault, Elizabeth Hewat & Catherine Vénien-Bryan. (2004) A Soluble VE-cadherin Fragment Forms 2D Arrays of Dimers upon Binding to a Lipid Monolayer. Journal of Molecular Biology 337:4, pages 881-892.
Crossref

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