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Transcriptional Regulation

STAT5 and Oct-1 Form a Stable Complex That Modulates Cyclin D1 Expression

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Pages 8934-8945 | Received 10 Feb 2003, Accepted 10 Sep 2003, Published online: 27 Mar 2023

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Thibault Mesplède, Marie-Laure Island, Nicolas Christeff, Fahrettin Petek, Janine Doly & Sébastien Navarro. (2005) The POU Transcription Factor Oct-1 Represses Virus-Induced Interferon A Gene Expression. Molecular and Cellular Biology 25:19, pages 8717-8731.
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Paul L. Hermonat, Hongqing Zhu, Maohua Cao & Jawahar L. Mehta. (2011) LOX-1 Transcription. Cardiovascular Drugs and Therapy 25:5, pages 393-400.
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Amy E. Geddis. (2010) Megakaryopoiesis. Seminars in Hematology 47:3, pages 212-219.
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Zhiyong Liao, Jacqueline Lutz & Marja T. Nevalainen. (2010) Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer. The International Journal of Biochemistry & Cell Biology 42:2, pages 186-192.
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Benoît LaurentVoahangy Randrianarison-HuetzVincent Maréchal, Patrick MayeuxIsabella Dusanter-FourtDominique Duménil. (2010) High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription. Blood 115:3, pages 687-695.
Crossref
Albert C Huang, Limei Hu, Stuart A Kauffman, Wei Zhang & Ilya Shmulevich. (2009) Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation. BMC Systems Biology 3:1.
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Zhiyi Guo, Jinshan Wang, Jun Yang, Ning-hua Wu, Ye Zhang & Yu-fei Shen. (2009) An inhibitory role of p53 via NF-κB element on the cyclin D1 gene under heat shock. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1789:11-12, pages 758-762.
Crossref
Lori A. Hazlehurst, Nadine N. BewryRajesh R. Nair & Javier Pinilla-Ibarz. (2009) Signaling Networks Associated with BCR–ABL–Dependent Transformation. Cancer Control 16:2, pages 100-107.
Crossref
Jinsuk Kang, Matthew Gemberling, Mitsuhiro Nakamura, Frank G. Whitby, Hiroshi Handa, William G. Fairbrother & Dean Tantin. (2009) A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. Genes & Development 23:2, pages 208-222.
Crossref
Mie Soda, Karl Willert, Kenneth Kaushansky & Amy E. Geddis. (2008) Inhibition of GSK-3β promotes survival and proliferation of megakaryocytic cells through a β-catenin-independent pathway. Cellular Signalling 20:12, pages 2317-2323.
Crossref
Sheng-Huei Yang, Ching-Ming Chien, Jung-Chen Su, Yeh-Long Chen, Long-Sen Chang & Shinne-Ren Lin. (2008) Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells. Journal of Biochemical and Molecular Toxicology 22:6, pages 396-404.
Crossref
Ching-Ming Chien, Sheng-Huei Yang, Kuei-Li Lin, Yeh-Long Chen, Long-Sen Chang & Shinne-Ren Lin. (2008) Novel indoloquinoline derivative, IQDMA, suppresses STAT5 phosphorylation and induces apoptosis in HL-60 cells. Chemico-Biological Interactions 176:1, pages 40-47.
Crossref
Takeo Minematsu, Takashi Harumi & Mitsuru Naito. (2008) Germ cell-specific expression of GFP gene induced by chicken vasa homologue ( Cvh ) promoter in early chicken embryos . Molecular Reproduction and Development 75:10, pages 1515-1522.
Crossref
Shinya Ogawa, Masanobu Satake & Koichi Ikuta. (2008) Physical and Functional Interactions between STAT5 and Runx Transcription Factors. The Journal of Biochemistry 143:5, pages 695-709.
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Ana Ramírez de Molina, David Gallego-Ortega, Jacinto Sarmentero-Estrada, David Lagares, Teresa Gómez del Pulgar, Eva Bandrés, Jesús García-Foncillas & Juan Carlos Lacal. (2008) Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: Implications in cancer therapy. The International Journal of Biochemistry & Cell Biology 40:9, pages 1753-1763.
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Gui-Ae Jeong, Eric T. Choi & Jeong-Hwan Chang. (2008) Octamer-Binding Transcription Factor-1 Gene Is Upregulated in Primary Varicose Veins. Annals of Vascular Surgery 22:1, pages 115-120.
Crossref
Gui-Ae Jeong, Eric T. Choi & Jeong-Hwan Chang. (2008) El gen del factor de transcripción-1 de unión a octámero muestra una expresión aumentada en las venas varicosas primarias. Anales de Cirugía Vascular 22:1, pages 127-133.
Crossref
Gui-Ae Jeong, Eric T. Choi & Jeong-Hwan Chang. (2008) Le gène de transcription pour le Facteur-1 fixant l'octamère est stimulé au niveau des veines variqueuses primaires. Annales de Chirurgie Vasculaire 22:1, pages 122-127.
Crossref
Sangkil Nam, Ann Williams, Adina Vultur, Alan List, Kapil Bhalla, David Smith, Francis Y. Lee & Richard Jove. (2007) Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells. Molecular Cancer Therapeutics 6:4, pages 1400-1405.
Crossref
Bing DongFeng-Qi Zhao. (2006) Involvement of the ubiquitous Oct-1 transcription factor in hormonal induction of β-casein gene expression. Biochemical Journal 401:1, pages 57-64.
Crossref
Itamar Barash. (2006) Stat5 in the mammary gland: Controlling normal development and cancer. Journal of Cellular Physiology 209:2, pages 305-313.
Crossref
R. Kandel, S.-Q. Li, R. Bell, J. Wunder, P. Ferguson, A. Kauzman, J.A. Diehl & J. Werier. (2006) Cyclin D1 and p21 is elevated in the giant cells of giant cell tumors. Journal of Orthopaedic Research 24:3, pages 428-437.
Crossref
Sylvane Desrivières, Christian Kunz, Itamar Barash, Vida Vafaizadeh, Corina Borghouts & Bernd Groner. (2006) The Biological Functions of the Versatile Transcription Factors STAT3 and STAT5 and New Strategies for their Targeted Inhibition. Journal of Mammary Gland Biology and Neoplasia 11:1, pages 75-87.
Crossref
Gilles M. Leclerc & Fredric R. Boockfor. (2005) Identification of a novel OCT1 binding site that is necessary for the elaboration of pulses of rat GnRH promoter activity. Molecular and Cellular Endocrinology 245:1-2, pages 86-92.
Crossref
Raquel Almeida, José Almeida, Michal Shoshkes, Nuno Mendes, Patrícia Mesquita, Elisabete Silva, Isabelle Van Seuningen, Celso A Reis, Filipe Santos-Silva & Leonor David. (2005) OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells. The Journal of Pathology 207:4, pages 396-401.
Crossref
Rajakishore Mishra & Bibhu Ranjan Das. (2005) Activation of STAT5-cyclin D1 Pathway in Chewing Tobacco Mediated Oral Squamous Cell Carcinoma. Molecular Biology Reports 32:3, pages 159-166.
Crossref
Eric Bertolino, Karen Reddy, Kay L Medina, Evan Parganas, James Ihle & Harinder Singh. (2005) Regulation of interleukin 7–dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nature Immunology 6:8, pages 836-843.
Crossref
Jennifer L. Brockman & Linda A. Schuler. (2005) Prolactin signals via Stat5 and Oct-1 to the proximal cyclin D1 promoter. Molecular and Cellular Endocrinology 239:1-2, pages 45-53.
Crossref
Marie-Christine Rouyez, Marta Lestingi, Martine Charon, Serge Fichelson, Agnès Buzyn & Isabelle Dusanter-Fourt. (2005) IFN Regulatory Factor-2 Cooperates with STAT1 to Regulate Transporter Associated with Antigen Processing-1 Promoter Activity. The Journal of Immunology 174:7, pages 3948-3958.
Crossref
Claudia M. Litterst, Stefanie Kliem, Marco Lodrini & Edith Pfitzner. 2005. 359 386 .
Mahendra Rao. (2004) Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells. Developmental Biology 275:2, pages 269-286.
Crossref
Attila Reményi, Hans R Schöler & Matthias Wilmanns. (2004) Combinatorial control of gene expression. Nature Structural & Molecular Biology 11:9, pages 812-815.
Crossref

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