19
Views
63
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

The c-myc Insulator Element and Matrix Attachment Regions Definethe c-myc ChromosomalDomain

, , , , &
Pages 9338-9348 | Received 06 Jun 2003, Accepted 12 Sep 2003, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Giuliana P. Mognol, Patricia S. de Araujo-Souza, Bruno K. Robbs, Leonardo K. Teixeira & Joao P.B. Viola. (2012) Transcriptional regulation of the c-Myc promoter by NFAT1 involves negative and positive NFAT-responsive elements. Cell Cycle 11:5, pages 1014-1028.
Read now
Melissa J. MacPherson, Linda G. Beatty, Wenjing Zhou, Minjie Du & Paul D. Sadowski. (2009) The CTCF Insulator Protein Is Posttranslationally Modified by SUMO. Molecular and Cellular Biology 29:3, pages 714-725.
Read now
Phuongmai Nguyen, Gil Bar-Sela, Lunching Sun, Kheem S. Bisht, Hengmi Cui, Elise Kohn, Andrew P. Feinberg & David Gius. (2008) BAT3 and SET1A Form a Complex with CTCFL/BORIS To Modulate H3K4 Histone Dimethylation and Gene Expression. Molecular and Cellular Biology 28:21, pages 6720-6729.
Read now
Francine E. Garrett, Alexander V. Emelyanov, Manuel A. Sepulveda, Patrick Flanagan, Sabrina Volpi, Fubin Li, Dmitry Loukinov, Laurel A. Eckhardt, Victor V. Lobanenkov & Barbara K. Birshtein. (2005) Chromatin Architecture near a Potential 3′ End of the Igh Locus Involves Modular Regulation of Histone Modifications during B-Cell Development and In Vivo Occupancy at CTCF Sites. Molecular and Cellular Biology 25:4, pages 1511-1525.
Read now

Articles from other publishers (59)

Antonina Hafner, Minhee Park, Scott E. Berger, Sedona E. Murphy, Elphège P. Nora & Alistair N. Boettiger. (2023) Loop stacking organizes genome folding from TADs to chromosomes. Molecular Cell 83:9, pages 1377-1392.e6.
Crossref
Chen Wang, Xinlu Yu, Sai Ding, Yang Liu, Hongxia Zhang, Jingbo Fu, Bing Yu & Haiying Zhu. (2022) Induced hepatic stem cells maintain self-renewal through the high expression of Myc coregulated by TET1 and CTCF. Cell & Bioscience 12:1.
Crossref
Fatemeh Amjadi-Moheb, Alireza Paniri & Haleh Akhavan-Niaki. (2021) Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation: Implications for Cancer Therapy. Cancer Research 81:8, pages 1925-1936.
Crossref
Jurian Schuijers, John Colonnese Manteiga, Abraham Selby Weintraub, Daniel Sindt Day, Alicia Viridiana Zamudio, Denes Hnisz, Tong Ihn Lee & Richard Allen Young. (2018) Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism. Cell Reports 23:2, pages 349-360.
Crossref
Kashyap Dave, Inderpreet Sur, Jian Yan, Jilin Zhang, Eevi Kaasinen, Fan Zhong, Leander Blaas, Xiaoze Li, Shabnam Kharazi, Charlotte Gustafsson, Ayla De Paepe, Robert Månsson & Jussi Taipale. (2017) Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth. eLife 6.
Crossref
Diego Germini, Yara Bou Saada, Tatiana Tsfasman, Kristina Osina, Chloé Robin, Nikolay Lomov, Mikhail Rubtsov, Nikolajs Sjakste, Mar≿ Lipinski & Yegor Vassetzky. (2017) A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools. Molecular Therapy - Methods & Clinical Development 5, pages 43-50.
Crossref
SAMIRA SADEGHI, ZOHREH HOJATI & HOSSEIN TABATABAEIAN. (2017) Cooverexpression of EpCAM and c-myc genes in malignant breast tumours. Journal of Genetics 96:1, pages 109-118.
Crossref
Adriana Gonzalez-Sandoval & Susan M. Gasser. (2016) On TADs and LADs: Spatial Control Over Gene Expression. Trends in Genetics 32:8, pages 485-495.
Crossref
Tatiana Gerasimova, Changying Guo, Amalendu Ghosh, Xiang Qiu, Lindsey Montefiori, Jiyoti Verma-Gaur, Nancy M. Choi, Ann J. Feeney & Ranjan Sen. (2015) A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation . Genes & Development 29:16, pages 1683-1695.
Crossref
Cassandra Mostocotto, Mariarosaria Carbone, Cecilia Battistelli, Agnese Ciotti, Paolo Amati & Rossella Maione. (2014) Poly(ADP-Ribosyl)ation Is Required to Modulate Chromatin Changes at c-MYC Promoter during Emergence from Quiescence. PLoS ONE 9:7, pages e102575.
Crossref
Jeanne AllinneAndrei PichuginOlga IarovaiaManel KlibiAna BaratEwa Zlotek-ZlotkiewiczDiana MarkozashviliNatalia PetrovaValérie Camara-Clayette, Elena IoudinkovaJoëlle WielsSergey V. Razin, Vincent Ribrag, Marc LipinskiYegor S. Vassetzky. (2014) Perinucleolar relocalization and nucleolin as crucial events in the transcriptional activation of key genes in mantle cell lymphoma. Blood 123:13, pages 2044-2053.
Crossref
Lylia Ouboussad, Sarah Kreuz & Pascal F. Lefevre. (2013) CTCF depletion alters chromatin structure and transcription of myeloid-specific factors. Journal of Molecular Cell Biology 5:5, pages 308-322.
Crossref
Lusha Ji, Rui Xu, Longtao Lu, Jiedao Zhang, Guodong Yang, Jinguang Huang, Changai Wu & Chengchao Zheng. (2013) TM6, a novel nuclear matrix attachment region, enhances its flanking gene expression through influencing their chromatin structure. Molecules and Cells 36:2, pages 127-137.
Crossref
Brandon Thomas, Eric Rubio, Niklas Krumm, Pilib Broin, Karol Bomsztyk, Piri Welcsh, John Greally, Aaron Golden & Anton Krumm. 2013. Epigenetics, Environment, and Genes. Epigenetics, Environment, and Genes 205 237 .
Anna Gimigliano, Linda Mannini, Laura Bianchi, Michele Puglia, Matthew A. Deardorff, Stefania Menga, Ian D. Krantz, Antonio Musio & Luca Bini. (2012) Proteomic Profile Identifies Dysregulated Pathways in Cornelia de Lange Syndrome Cells with Distinct Mutations in SMC1A and SMC3 Genes . Journal of Proteome Research 11:12, pages 6111-6123.
Crossref
Jingping Yang & Victor G. Corces. 2012. Toxicology and Epigenetics. Toxicology and Epigenetics 539 567 .
Anna Busanello, Cecilia Battistelli, Mariarosaria Carbone, Cassandra Mostocotto & Rossella Maione. (2012) MyoD regulates p57 kip2 expression by interacting with a distant cis -element and modifying a higher order chromatin structure. Nucleic Acids Research 40:17, pages 8266-8275.
Crossref
Hebing Chen, Yao Tian, Wenjie Shu, Xiaochen Bo & Shengqi Wang. (2012) Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome. PLoS ONE 7:7, pages e41374.
Crossref
Manuel Rosa-Garrido, Laura Ceballos, Pilar Alonso-Lecue, Cristina Abraira, M. Dolores Delgado & Alberto Gandarillas. (2012) A Cell Cycle Role for the Epigenetic Factor CTCF-L/BORIS. PLoS ONE 7:6, pages e39371.
Crossref
Martin HeroldMarek BartkuhnRainer Renkawitz. (2012) CTCF: insights into insulator function during development. Development 139:6, pages 1045-1057.
Crossref
Gráinne BarkessAdam G West. (2012) Chromatin insulator elements: establishing barriers to set heterochromatin boundaries. Epigenomics 4:1, pages 67-80.
Crossref
Katrin Zielke, Florian Full, Natascha Teufert, Monika Schmidt, Ingrid Müller-Fleckenstein, Barbara Alberter & Armin Ensser. (2012) The Insulator Protein CTCF Binding Sites in the orf73 /LANA Promoter Region of Herpesvirus Saimiri Are Involved in Conferring Episomal Stability in Latently Infected Human T Cells . Journal of Virology 86:3, pages 1862-1873.
Crossref
Francesco Paolo Fiorentino & Antonio Giordano. (2012) The tumor suppressor role of CTCF. Journal of Cellular Physiology 227:2, pages 479-492.
Crossref
Brandon J Thomas, Eric D Rubio, Niklas Krumm, Pilib Ó Broin, Karol Bomsztyk, Piri Welcsh, John M Greally, Aaron A Golden & Anton Krumm. (2011) Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene. Epigenetics & Chromatin 4:1.
Crossref
Hyojeung Kang & Paul M. Lieberman. (2011) Mechanism of Glycyrrhizic Acid Inhibition of Kaposi's Sarcoma-Associated Herpesvirus: Disruption of CTCF-Cohesin-Mediated RNA Polymerase II Pausing and Sister Chromatid Cohesion. Journal of Virology 85:21, pages 11159-11169.
Crossref
Juan Carabana, Akiko Watanabe, Bingtao Hao & Michael S. Krangel. (2011) A Barrier-Type Insulator Forms a Boundary between Active and Inactive Chromatin at the Murine TCRβ Locus. The Journal of Immunology 186:6, pages 3556-3562.
Crossref
Jingping Yang & Victor G. Corces. 2011. 43 76 .
Suzanne van de Nobelen, Manuel Rosa-Garrido, Joerg Leers, Helen Heath, Widia Soochit, Linda Joosen, Iris Jonkers, Jeroen Demmers, Michael van der Reijden, Verónica Torrano, Frank Grosveld, M Dolores Delgado, Rainer Renkawitz, Niels Galjart & Frank Sleutels. (2010) CTCF regulates the local epigenetic state of ribosomal DNA repeats. Epigenetics & Chromatin 3:1.
Crossref
Michèle Amouyal. (2010) Gene insulation. Part II: natural strategies in vertebrates. Biochemistry and Cell Biology 88:6, pages 885-898.
Crossref
Jenny M. Rhodes, Fiona K. Bentley, Cristin G. Print, Dale Dorsett, Ziva Misulovin, Emma J. Dickinson, Kathryn E. Crosier, Philip S. Crosier & Julia A. Horsfield. (2010) Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. Developmental Biology 344:2, pages 637-649.
Crossref
J. C. Rivera-Mulia & A. Aranda-Anzaldo. (2010) Determination of the in vivo structural DNA loop organization in the genomic region of the rat albumin locus by means of a topological approach. DNA Research 17:1, pages 23-35.
Crossref
E. Molto, A. Fernandez & L. Montoliu. (2009) Boundaries in vertebrate genomes: different solutions to adequately insulate gene expression domains. Briefings in Functional Genomics and Proteomics 8:4, pages 283-296.
Crossref
Jennifer E. Phillips & Victor G. Corces. (2009) CTCF: Master Weaver of the Genome. Cell 137:7, pages 1194-1211.
Crossref
Jinglan Liu, Zhe Zhang, Masashige Bando, Takehiko Itoh, Matthew A. Deardorff, Dinah Clark, Maninder Kaur, Stephany Tandy, Tatsuro Kondoh, Eric Rappaport, Nancy B. Spinner, Hugo Vega, Laird G. Jackson, Katsuhiko Shirahige & Ian D. Krantz. (2009) Transcriptional Dysregulation in NIPBL and Cohesin Mutant Human Cells. PLoS Biology 7:5, pages e1000119.
Crossref
Jordanka Zlatanova & Paola Caiafa. (2009) CTCF and its protein partners: divide and rule?. Journal of Cell Science 122:9, pages 1275-1284.
Crossref
Lambertus A Kiemeney, Steinunn Thorlacius, Patrick Sulem, Frank Geller, Katja K H Aben, Simon N Stacey, Julius Gudmundsson, Margret Jakobsdottir, Jon T Bergthorsson, Asgeir Sigurdsson, Thorarinn Blondal, J Alfred Witjes, Sita H Vermeulen, Christina A Hulsbergen-van de Kaa, Dorine W Swinkels, Martine Ploeg, Erik B Cornel, Henk Vergunst, Thorgeir E Thorgeirsson, Daniel Gudbjartsson, Sigurjon A Gudjonsson, Gudmar Thorleifsson, Kari T Kristinsson, Magali Mouy, Steinunn Snorradottir, Donatella Placidi, Marcello Campagna, Cecilia Arici, Kvetoslava Koppova, Eugene Gurzau, Peter Rudnai, Eliane Kellen, Silvia Polidoro, Simonetta Guarrera, Carlotta Sacerdote, Manuel Sanchez, Berta Saez, Gabriel Valdivia, Charlotta Ryk, Petra de Verdier, Annika Lindblom, Klaus Golka, D Timothy Bishop, Margaret A Knowles, Sigfus Nikulasson, Vigdis Petursdottir, Eirikur Jonsson, Gudmundur Geirsson, Baldvin Kristjansson, Jose I Mayordomo, Gunnar Steineck, Stefano Porru, Frank Buntinx, Maurice P Zeegers, Tony Fletcher, Rajiv Kumar, Giuseppe Matullo, Paolo Vineis, Anne E Kiltie, Jeffrey R Gulcher, Unnur Thorsteinsdottir, Augustine Kong, Thorunn Rafnar & Kari Stefansson. (2008) Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nature Genetics 40:11, pages 1307-1312.
Crossref
Mario La Farina, Maurizio Bellavia, Marcello Tagliavia, Vincenzo Eterno, Paolo Colomba, Angelo Scibetta & Ida Albanese. (2008) Two distinct amplification events of the c-myc locus in a colorectal tumour. Journal of Cellular Physiology 217:1, pages 34-39.
Crossref
Le-Ben WanHua PanSridhar HannenhalliYong ChengJun MaAndrew FedoriwVictor LobanenkovKeith E. LathamRichard M. SchultzMarisa S. Bartolomei. (2008) Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development. Development 135:16, pages 2729-2738.
Crossref
M. Weil, Cristi Galindo & Harold Garner. (2008) A high-resolution survey of the effects of 5-aza-dC treatment on the chromatin state of MCF7 breast cancer cells [Engineering in Genomics]. IEEE Engineering in Medicine and Biology Magazine 27:4, pages 86-100.
Crossref
Eric D. RubioDavid J. ReissPiri L. Welcsh, Christine M. DistecheGalina N. Filippova, Nitin S. BaligaRuedi Aebersold, Jeffrey A. RanishAnton Krumm. (2008) CTCF physically links cohesin to chromatin. Proceedings of the National Academy of Sciences 105:24, pages 8309-8314.
Crossref
William Stedman, Hyojeung Kang, Shu Lin, Joseph L Kissil, Marisa S Bartolomei & Paul M Lieberman. (2008) Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. The EMBO Journal 27:4, pages 654-666.
Crossref
Inken Wierstra & Jürgen Alves. 2008. 113 333 .
Jun-ichiro Komura, Hironobu Ikehata & Tetsuya Ono. (2007) Chromatin fine structure of the c- MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis . Proceedings of the National Academy of Sciences 104:40, pages 15741-15746.
Crossref
Janette Gomos-Klein, Faith Harrow, Jemma Alarcón & Benjamin D. Ortiz. (2007) CTCF-Independent, but Not CTCF-Dependent, Elements Significantly Contribute to TCR-α Locus Control Region Activity. The Journal of Immunology 179:2, pages 1088-1095.
Crossref
Jamie R Schoenborn, Michael O Dorschner, Masayuki Sekimata, Deanna M Santer, Maria Shnyreva, David R Fitzpatrick, John A Stamatoyannopoulos & Christopher B Wilson. (2007) Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-γ. Nature Immunology 8:7, pages 732-742.
Crossref
Satoshi Watanabe, Sachiko Watanabe, Naoaki Sakamoto, Masahiro Sato & Koji Akasaka. (2006) Functional analysis of the sea urchin-derived arylsulfatase (Ars)-element in mammalian cells. Genes to Cells 11:9, pages 1009-1021.
Crossref
Ko Ishihara, Mitsuo Oshimura & Mitsuyoshi Nakao. (2006) CTCF-Dependent Chromatin Insulator Is Linked to Epigenetic Remodeling. Molecular Cell 23:5, pages 733-742.
Crossref
O. G. Maksimenko, D. A. Chetverina & P. G. Georgiev. (2006) Insulators of higher eukaryotes: Properties, mechanisms of action, and role in transcriptional regulation. Russian Journal of Genetics 42:8, pages 845-857.
Crossref
Damien Grégoire, Konstantin Brodolin & Marcel Méchali. (2006) HoxB domain induction silences DNA replication origins in the locus and specifies a single origin at its boundary. EMBO reports 7:8, pages 812-816.
Crossref
Juhong Liu, Fedor Kouzine, Zuqin Nie, Hye-Jung Chung, Zichrini Elisha-Feil, Achim Weber, Keji Zhao & David Levens. (2006) The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression. The EMBO Journal 25:10, pages 2119-2130.
Crossref
XAVIER LE GUEZENNEC, ARIE B. BRINKMAN, MICHIEL VERMEULEN, SERGEI G. DENISSOV, CINZIA GAZZIOLA, MARION E. LOHRUM & HENK G. STUNNENBERG. (2005) Targeted discovery tools: proteomics and chromatin immunoprecipitation-on-chip. BJU International 96:s2, pages 16-22.
Crossref
Veronica Volgina, Pi-Chen Yam & Katherine L. Knight. (2005) A negative regulatory element in the rabbit 3′IgH chromosomal region. International Immunology 17:8, pages 973-982.
Crossref
Stephen D. Farris, Eric D. Rubio, James J. Moon, Wendy M. Gombert, Brad H. Nelson & Anton Krumm. (2005) Transcription-induced Chromatin Remodeling at the c-myc Gene Involves the Local Exchange of Histone H2A.Z. Journal of Biological Chemistry 280:26, pages 25298-25303.
Crossref
Verónica Torrano, Igor Chernukhin, France Docquier, Vivien D'Arcy, Javier León, Elena Klenova & M. Dolores Delgado. (2005) CTCF Regulates Growth and Erythroid Differentiation of Human Myeloid Leukemia Cells. Journal of Biological Chemistry 280:30, pages 28152-28161.
Crossref
S. V. Razin & O. V. Iarovaia. (2005) Spatial Organization of DNA in the Nucleus May Determine Positions of Recombination Hot Spots. Molecular Biology 39:4, pages 543-548.
Crossref
Adam G. West & Peter Fraser. (2005) Remote control of gene transcription. Human Molecular Genetics 14:suppl_1, pages R101-R111.
Crossref
James K. ParkMiriam H. Feuerman. (2005) Afr2 Regulation Occurs Cell-Autonomously In Vitro But Is Not Conferred on Episomal DNA in Transient Assays . DNA and Cell Biology 24:3, pages 189-198.
Crossref
Igor Kuzmin, Laura Geil, Lauren Gibson, Tiziana Cavinato, Dmitry Loukinov, Victor Lobanenkov & Michael I. Lerman. (2005) Transcriptional Regulator CTCF Controls Human Interleukin 1 Receptor-associated Kinase 2 Promoter. Journal of Molecular Biology 346:2, pages 411-422.
Crossref
Annabelle Lewis & Adele Murrell. (2004) Genomic Imprinting: CTCF Protects the Boundaries. Current Biology 14:7, pages R284-R286.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.