Advanced search
Publication Cover
Molecular and Cellular Biology Volume 23, 2003 - Issue 3
Submit an article Journal homepage
19
Views
11
CrossRef citations to date
0
Altmetric
Mammalian Genetic Models with Minimal or Complex Phenotypes

Liver-Specific Reactivation of the Inactivated Hnf-1α Gene: Elimination of Liver Dysfunction To Establish a Mouse MODY3 Model

Ying-Hue Lee1 Laboratory of Molecular Pathology, Institute of Molecular Biology, Academia Sinica, Taipei115Correspondence[email protected]
,
Mark A. Magnuson2 Departments of Molecular Physiology and Biophysics and of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee37233
,
Vijayakumar Muppala1 Laboratory of Molecular Pathology, Institute of Molecular Biology, Academia Sinica, Taipei115
&
Shih-Shun Chen1 Laboratory of Molecular Pathology, Institute of Molecular Biology, Academia Sinica, Taipei115;3 Graduate Institute of Life Sciences, National Defense Medical Center, Taipei100, TaiwanCorrespondence[email protected]
Pages 923-932 | Received 13 May 2002, Accepted 21 Oct 2002, Published online: 27 Mar 2023

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Mengdie Hu, Xiuting Huang, Xueyao Han & Linong Ji. (2020) Loss of HNF1α Function Contributes to Hepatocyte Proliferation and Abnormal Cholesterol Metabolism via Downregulating miR-122: A Novel Mechanism of MODY3. Diabetes, Metabolic Syndrome and Obesity 13, pages 627-639.
Read now

Articles from other publishers (10)

Virginie Lam, Ryusuke Takechi, Mark J. Hackett, Roslyn Francis, Michael Bynevelt, Liesl M. Celliers, Michael Nesbit, Somayra Mamsa, Frank Arfuso, Sukanya Das, Frank Koentgen, Maree Hagan, Lincoln Codd, Kirsty Richardson, Brenton O’Mara, Rainer K. Scharli, Laurence Morandeau, Jonathan Gauntlett, Christopher Leatherday, Jan Boucek & John C. L. Mamo. (2021) Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype. PLOS Biology 19:9, pages e3001358.
Crossref
Chun-Ping Lu, Chien-Yu Huang, Szu-Hsuan Wang, Chih-Hsien Chiu, Lan-Hui Li, Kuo-Feng Hua & Tzu-Hua Wu. (2018) Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin. Chemico-Biological Interactions 290, pages 12-18.
Crossref
Toru Sugiyama & Hiroshi Tsuda. 2011. Rare and Uncommon Gynecological Cancers. Rare and Uncommon Gynecological Cancers 91 103 .
S. GlaserM. WangY. Ueno, J. Venter, K. WangH. ChenG. Alpini & A. Holterman. (2010) Differential transcriptional characteristics of small and large biliary epithelial cells derived from small and large bile ducts. American Journal of Physiology-Gastrointestinal and Liver Physiology 299:3, pages G769-G777.
Crossref
Zhanquan Shi, Nadine Dragin, Marina Gálvez-Peralta, Lucia F. Jorge-Nebert, Marian L. Miller, Bin Wang & Daniel W. Nebert. (2010) Organ-Specific Roles of CYP1A1 during Detoxication of Dietary Benzo[ a ]pyrene . Molecular Pharmacology 78:1, pages 46-57.
Crossref
Ishtiaq Qadri, Ling-Jia Hu, Mieko Iwahashi, Subhi Al-Zuabi, Linda C. Quattrochi & Francis R. Simon. (2009) Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2). Toxicology and Applied Pharmacology 234:3, pages 281-292.
Crossref
Wan-Yi Lin, Yu-Jie Hu & Ying-Hue Lee. (2008) Hepatocyte nuclear factor-1α regulates glucocorticoid receptor expression to control postnatal body growth. American Journal of Physiology-Gastrointestinal and Liver Physiology 295:3, pages G542-G551.
Crossref
Michael Strehle & Stefan Britisch. 2008. Grundlagen der Molekularen Medizin. Grundlagen der Molekularen Medizin 207 241 .
Atsushi Higashiguchi, Taketo Yamada, Nobuyuki Susumu, Taisuke Mori, Atsushi Suzuki, Daisuke Aoki & Michiie Sakamoto. (2007) Specific expression of hepatocyte nuclear factor-1? in the ovarian clear cell adenocarcinoma and its application to cytological diagnosis. Cancer Science 98:3, pages 387-391.
Crossref
Sachiko Kitanaka, Yuko Miki, Yasuhide Hayashi & Takashi Igarashi. (2004) Promoter-Specific Repression of Hepatocyte Nuclear Factor (HNF)-1β and HNF-1α Transcriptional Activity by an HNF-1β Missense Mutant Associated with Type 5 Maturity-Onset Diabetes of the Young with Hepatic and Biliary Manifestations. The Journal of Clinical Endocrinology & Metabolism 89:3, pages 1369-1378.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.