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Mammalian Genetic Models with Minimal or Complex Phenotypes

TAB2 Is Essential for Prevention of Apoptosis in Fetal Liver but Not for Interleukin-1 Signaling

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Pages 1231-1238 | Received 06 Aug 2002, Accepted 15 Nov 2002, Published online: 27 Mar 2023

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Haifeng Yin, Xiaoyun Guo, Yi Chen, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Rachel Steinmetz & Qinghang Liu. (2022) TAB2 deficiency induces dilated cardiomyopathy by promoting RIPK1-dependent apoptosis and necroptosis. Journal of Clinical Investigation 132:4.
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Jennifer Hanson, Daniel Brezavar, Susan Hughes, Shivarajan Amudhavalli, Emily Fleming, Dihong Zhou, Joseph T. Alaimo & Penelope E. Bonnen. (2021) TAB2 variants cause cardiovascular heart disease, connective tissue disorder, and developmental delay . Clinical Genetics 101:2, pages 214-220.
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Zhipeng Tai, Pengpeng Guan, Ting Zhang, Wenye Liu, Lingya Li, You Wu, Guoliang Li & Jing-Xia Liu. (2022) Effects of parental environmental copper stress on offspring development: DNA methylation modification and responses of differentially methylated region-related genes in transcriptional expression. Journal of Hazardous Materials 424, pages 127600.
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Zhiwen Gu, Xueying Chen, Wenyong Yang, Yu Qi, Hui Yu, Xiaomeng Wang, Yanqiu Gong, Qianqian Chen, Bo Zhong, Lunzhi Dai, Shiqian Qi, Zhiqiang Zhang, Huiyuan Zhang & Hongbo Hu. (2020) The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response. Cellular & Molecular Immunology 18:8, pages 1981-1994.
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Qiuyue Li, Siling Li, Chunjie Xu, Jing Zhao, Lin Hou, Fuyang Jiang, Zhonghui Zhu, Yan Wang & Lin Tian. (2021) microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro. Cell Biology and Toxicology.
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Xiaomeng Ren, Junxia Cui, Tianjun Xu & Yuena Sun. (2021) microRNA-128 inhibits the inflammatory responses by targeting TAB2 in miiuy croaker, Miichthysmiiuy. Developmental & Comparative Immunology 117, pages 103976.
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Juliane Totzke, Scott A. Scarneo, Kelly W. Yang & Timothy A. J. Haystead. (2020) TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases. Open Biology 10:9.
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Harald Braun & Jens Staal. (2020) Stabilization of the TAK1 adaptor proteins TAB2 and TAB3 is critical for optimal NF‐κB activation. The FEBS Journal 287:15, pages 3161-3164.
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Qiaoqiao Zhou, Cheng Cheng, Yujuan Wei, Jing Yang, Wanzhu Zhou, Qiuyi Song, Mengxiang Ke, Wanyao Yan, Ling Zheng, Yu Zhang & Kun Huang. (2020) USP15 potentiates NF‐κB activation by differentially stabilizing TAB2 and TAB3. The FEBS Journal 287:15, pages 3165-3183.
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Yaping Yang, Chao Yang, Ying-fang Guo, Pei Liu, Shuai Guo, Jing Yang, Arshad Zahoor, Aftab Shaukat & Ganzhen Deng. (2019) MiR-142a-3p alleviates Escherichia coli derived lipopolysaccharide-induced acute lung injury by targeting TAB2. Microbial Pathogenesis 136, pages 103721.
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Silvia Morlino, Annalucia Carbone, Marco Ritelli, Carmela Fusco, Vincenzo Giambra, Grazia Nardella, Angelantonio Notarangelo, Patrizio Panelli, Gianluigi Mazzoccoli, Nicoletta Zoppi, Paola Grammatico, Emma M Wade, Marina Colombi, Marco Castori & Lucia Micale. (2019) TAB2 c.1398dup variant leads to haploinsufficiency and impairs extracellular matrix homeostasis . Human Mutation 40:10, pages 1886-1898.
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Luping Wang, Lihua Jiang, Gang Liu, Changwen Wu, Bingjian Liu, Liqin Liu, Zhenming Lv, Li Gong & Xinjin Song. (2019) Molecular characterization and expression of TAK-binding proteins (TAB1-3) in Larimichthys crocea infected by Vibrio parahemolyticus and LPS. Developmental & Comparative Immunology 98, pages 108-118.
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