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Molecular and Cellular Biology Volume 23, 2003 - Issue 8
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Cell Growth and Development

Translocation of CrkL to Focal Adhesions Mediates Integrin-Induced Migration Downstream of Src Family Kinases

Leiming Li1 Committees on Cell Physiology;2 The Ben May Institute for Cancer Research and Center for Molecular Oncology, The University of Chicago, Chicago, Illinois60637
,
Deborah L. Guris2 The Ben May Institute for Cancer Research and Center for Molecular Oncology, The University of Chicago, Chicago, Illinois60637
,
Masaya Okura2 The Ben May Institute for Cancer Research and Center for Molecular Oncology, The University of Chicago, Chicago, Illinois60637
&
Akira Imamoto1 Committees on Cell Physiology;2 The Ben May Institute for Cancer Research and Center for Molecular Oncology, The University of Chicago, Chicago, Illinois60637;3 Cancer BiologyCorrespondence[email protected]
Pages 2883-2892 | Received 27 Nov 2002, Accepted 30 Jan 2003, Published online: 27 Mar 2023

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Ryon Graf, Simone Barbero, Nadine Keller, Lauren Chen, Sean Uryu, David Schlaepfer & Dwayne Stupack. (2013) Src-inducible association of CrkL with procaspase-8 promotes cell migration. Cell Adhesion & Migration 7:4, pages 362-369.
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Ji-Heui Seo, Atsushi Suenaga, Mariko Hatakeyama, Makoto Taiji & Akira Imamoto. (2009) Structural and Functional Basis of a Role for CRKL in a Fibroblast Growth Factor 8-Induced Feed-Forward Loop. Molecular and Cellular Biology 29:11, pages 3076-3087.
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Zeenat S. Hakim, Laura A. DiMichele, Jason T. Doherty, Jonathon W. Homeister, Hilary E. Beggs, Louis F. Reichardt, Robert J. Schwartz, Joseph Brackhan, Oliver Smithies, Christopher P. Mack & Joan M. Taylor. (2007) Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment. Molecular and Cellular Biology 27:15, pages 5352-5364.
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Taeju Park. (2021) Crk and CrkL as Therapeutic Targets for Cancer Treatment. Cells 10:4, pages 739.
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Fabian C. Franke, Benjamin O. Slusarenko, Thomas Engleitner, Widya Johannes, Melanie Laschinger, Roland Rad, Ulrich Nitsche & Klaus‐Peter Janssen. (2020) Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial–mesenchymal transition and colorectal cancer aggressiveness. International Journal of Cancer 147:6, pages 1715-1731.
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Nathan H. Roy, Mahinbanu Mammadli, Janis K. Burkhardt & Mobin Karimi. (2020) CrkL is required for donor T cell migration to GvHD target organs. Oncotarget 11:17, pages 1505-1514.
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Andrew J. Spracklen, Emma M. Thornton-Kolbe, Alison N. Bonner, Alexandru Florea, Peter J. Compton, Rodrigo Fernandez-Gonzalez & Mark Peifer. (2019) The Crk adapter protein is essential for Drosophila embryogenesis, where it regulates multiple actin-dependent morphogenic events . Molecular Biology of the Cell 30:18, pages 2399-2421.
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Jing Zhang, Xueliang Gao, Fabienne Schmit, Guillaume Adelmant, Michael J. Eck, Jarrod A. Marto, Jean J. Zhao & Thomas M. Roberts. (2017) CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells. Cell Reports 20:3, pages 549-557.
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