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Xianghua Piao, Xue Zhang, Ligang Wu & Joel G. Belasco. (2010) CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells. Molecular and Cellular Biology 30:6, pages 1486-1494.
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Shingo IZAWA. (2010) Ethanol Stress Response in the mRNA Flux of Saccharomyces cerevisiae. Bioscience, Biotechnology, and Biochemistry 74:1, pages 7-12.
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Gang Yao, Yueh-Chin Chiang, Chongxu Zhang, Darren J. Lee, Thomas M. Laue & Clyde L. Denis. (2007) PAB1 Self-Association Precludes Its Binding to Poly(A), Thereby Accelerating CCR4 Deadenylation In Vivo. Molecular and Cellular Biology 27:17, pages 6243-6253.
Read now
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Kim M. Keeling, Joe Salas-Marco, Lev Z. Osherovich & David M. Bedwell. (2006) Tpa1p Is Part of an mRNP Complex That Influences Translation Termination, mRNA Deadenylation, and mRNA Turnover in Saccharomyces cerevisiae. Molecular and Cellular Biology 26:14, pages 5237-5248.
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Nao Hosoda, Fabrice Lejeune & Lynne E. Maquat. (2006) Evidence that Poly(A) Binding Protein C1 Binds Nuclear Pre-mRNA Poly(A) Tails. Molecular and Cellular Biology 26:8, pages 3085-3097.
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Articles from other publishers (58)
Siyao Guo & Shuibin Lin. (2023) mRNA alternative polyadenylation (APA) in regulation of gene expression and diseases. Genes & Diseases 10:1, pages 165-174.
Crossref
Crossref
G. A. Zhouravleva, S. A. Bondarev, O. M. Zemlyanko & S. E. Moskalenko. (2022) Role of Proteins Interacting with the eRF1 and eRF3 Release Factors in the Regulation of Translation and Prionization. Molecular Biology 56:2, pages 147-165.
Crossref
Crossref
Dang Thi Tuong Vi, Shiori Fujii, Arvin Lapiz Valderrama, Ayaka Ito, Eri Matsuura, Ayaka Nishihata, Kaoru Irie, Yasuyuki Suda, Tomoaki Mizuno & Kenji Irie. (2021) Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources. PLOS ONE 16:5, pages e0251456.
Crossref
Crossref
Jiadong Liu, Mingwei Gao, Shuyang Xu, Yaping Chen, Kaixin Wu, He Liu, Jie Wang, Xuejie Yang, Junwei Wang, Weiwei Liu, Xichen Bao & Jiekai Chen. (2020) YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways. Cell Reports 32:10, pages 108120.
Crossref
Crossref
Clemens Grimm, Jann-Patrick Pelz, Cornelius Schneider, Katrin Schäffler & Utz Fischer. (2020) Crystal Structure of a Variant PAM2 Motif of LARP4B Bound to the MLLE Domain of PABPC1. Biomolecules 10:6, pages 872.
Crossref
Crossref
Ye-Eun Son, Ci Fu, Won-Hee Jung, Sang-Hun Oh, Jin-Hwan Kwak, Maria E. Cardenas, Joseph Heitman & Hee-Soo Park. (2019) Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans. Frontiers in Cellular and Infection Microbiology 9.
Crossref
Crossref
Ingmar B. Schäfer, Masami Yamashita, Jan Michael Schuller, Steffen Schüssler, Peter Reichelt, Mike Strauss & Elena Conti. (2019) Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell 177:6, pages 1619-1631.e21.
Crossref
Crossref
Angela L. Nicholson & Amy E. Pasquinelli. (2019) Tales of Detailed Poly(A) Tails. Trends in Cell Biology 29:3, pages 191-200.
Crossref
Crossref
Marco Brambilla, Francesca Martani, Stefano Bertacchi, Ilaria Vitangeli & Paola Branduardi. (2019)
The
Saccharomyces cerevisiae
poly (A) binding protein (Pab1): Master regulator of mRNA metabolism and cell physiology
. Yeast 36:1, pages 23-34.
Crossref
Crossref
Chyi-Ying A. Chen, Yueqiang Zhang, Yu Xiang, Leng Han & Ann-Bin Shyu. (2017) Antagonistic actions of two human Pan3 isoforms on global mRNA turnover. RNA 23:9, pages 1404-1418.
Crossref
Crossref
Duong Long Duy, Yasuyuki Suda & Kenji Irie. (2017) Cytoplasmic deadenylase Ccr4 is required for translational repression of LRG1 mRNA in the stationary phase. PLOS ONE 12:2, pages e0172476.
Crossref
Crossref
Patricia Richard, Vasupradha Vethantham & James L. Manley. 2017. SUMO Regulation of Cellular Processes. SUMO Regulation of Cellular Processes
15
33
.
Hao Du, Ya Zhao, Jinqiu He, Yao Zhang, Hairui Xi, Mofang Liu, Jinbiao Ma & Ligang Wu. (2016) YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex. Nature Communications 7:1.
Crossref
Crossref
Francesca Martani, Francesca Marano, Stefano Bertacchi, Danilo Porro & Paola Branduardi. (2015) The Saccharomyces cerevisiae poly(A) binding protein Pab1 as a target for eliciting stress tolerant phenotypes. Scientific Reports 5:1.
Crossref
Crossref
Britta Vallazza, Sebastian Petri, Marco A. Poleganov, Florian Eberle, Andreas N. Kuhn & Ugur Sahin. (2015) Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond. Wiley Interdisciplinary Reviews: RNA 6:5, pages 471-499.
Crossref
Crossref
Sylvain Roque, Marie Cerciat, Isabelle Gaugué, Liliana Mora, Aurélie G. Floch, Miklos de Zamaroczy, Valérie Heurgué-Hamard & Stephanie Kervestin. (2015)
Interaction between the poly(A)-binding protein Pab1 and the eukaryotic release factor eRF3 regulates translation termination but not mRNA decay in
Saccharomyces cerevisiae
. RNA 21:1, pages 124-134.
Crossref
Crossref
Jia-Xin Shi, Jia-Shu Li, Rong Hu, Yi Shi, Xin Su, Xiang-Jun Guo & Xiao-Mei Li. (2014) Tristetraprolin is involved in the glucocorticoid-mediated interleukin 8 repression. International Immunopharmacology 22:2, pages 480-485.
Crossref
Crossref
Milton T Stubbs & Elmar Wahle. (2014)
Deadenylation—a piece of
PAN
cake
. The EMBO Journal 33:14, pages 1503-1505.
Crossref
Crossref
Jana Wolf, Eugene Valkov, Mark D Allen, Birthe Meineke, Yuliya Gordiyenko, Stephen H McLaughlin, Tayla M Olsen, Carol V Robinson, Mark Bycroft, Murray Stewart & Lori A Passmore. (2014)
Structural basis for
P
an3 binding to
P
an2 and its function in
mRNA
recruitment and deadenylation
. The EMBO Journal 33:14, pages 1514-1526.
Crossref
Crossref
Stefanie Jonas, Mary Christie, Daniel Peter, Dipankar Bhandari, Belinda Loh, Eric Huntzinger, Oliver Weichenrieder & Elisa Izaurralde. (2014) An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay. Nature Structural & Molecular Biology 21:7, pages 599-608.
Crossref
Crossref
Ingmar B Schäfer, Michaela Rode, Fabien Bonneau, Steffen Schüssler & Elena Conti. (2014) The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase. Nature Structural & Molecular Biology 21:7, pages 591-598.
Crossref
Crossref
Yong-Bin Yan. (2014) Deadenylation: enzymes, regulation, and functional implications. Wiley Interdisciplinary Reviews: RNA 5:3, pages 421-443.
Crossref
Crossref
Aditi Singh, Igor Minia, Dorothea Droll, Abeer Fadda, Christine Clayton & Esteban Erben. (2022) Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks. Nucleic Acids Research 42:7, pages 4652-4668.
Crossref
Crossref
Jana WolfLori A. Passmore. (2014) mRNA deadenylation by Pan2–Pan3. Biochemical Society Transactions 42:1, pages 184-187.
Crossref
Crossref
Dianne M.A. van den Heuvel, Oliver Harschnitz, Leonard H. van den Berg & R. Jeroen Pasterkamp. (2014) Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?. Trends in Molecular Medicine 20:1, pages 25-35.
Crossref
Crossref
Micheline Fromont-Racine & Cosmin Saveanu. 2014. Fungal RNA Biology. Fungal RNA Biology
159
193
.
Aurelia Vavasseur & Yongsheng Shi. 2014. Fungal RNA Biology. Fungal RNA Biology
59
88
.
Mary Christie, Andreas Boland, Eric Huntzinger, Oliver Weichenrieder & Elisa Izaurralde. (2013) Structure of the PAN3 Pseudokinase Reveals the Basis for Interactions with the PAN2 Deadenylase and the GW182 Proteins. Molecular Cell 51:3, pages 360-373.
Crossref
Crossref
Yuichi Kimura, Kaoru Irie & Kenji Irie. (2013) Pbp1 Is Involved in Ccr4- and Khd1-Mediated Regulation of Cell Growth through Association with Ribosomal Proteins Rpl12a and Rpl12b. Eukaryotic Cell 12:6, pages 864-874.
Crossref
Crossref
Elmar Wahle & G. Sebastiaan Winkler. (2013) RNA decay machines: Deadenylation by the Ccr4–Not and Pan2–Pan3 complexes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:6-7, pages 561-570.
Crossref
Crossref
Udo Rüb, Ludger Schöls, Henry Paulson, Georg Auburger, Pawel Kermer, Joanna C. Jen, Kay Seidel, Horst-Werner Korf & Thomas Deller. (2013) Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7. Progress in Neurobiology 104, pages 38-66.
Crossref
Crossref
John S. BettAdel F. M. IbrahimAmit K. GargVan KellyPatrick PedrioliSonia RochaRonald T. Hay. (2013)
The P-body component USP52/PAN2 is a novel regulator of
HIF1A
mRNA stability
. Biochemical Journal 451:2, pages 185-194.
Crossref
Crossref
Kai-Lieh Huang, Amanda B. Chadee, Chyi-Ying A. Chen, Yueqiang Zhang & Ann-Bin Shyu. (2013) Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate. RNA 19:3, pages 295-305.
Crossref
Crossref
Chyi-Ying A. Chen & Ann-Bin Shyu. 2013. Ten Years of Progress in GW/P Body Research. Ten Years of Progress in GW/P Body Research
183
195
.
Roy Richardson, Clyde L. Denis, Chongxu Zhang, Maria E. O. Nielsen, Yueh-Chin Chiang, Morten Kierkegaard, Xin Wang, Darren J. Lee, Jens S. Andersen & Gang Yao. (2012) Mass spectrometric identification of proteins that interact through specific domains of the poly(A) binding protein. Molecular Genetics and Genomics 287:9, pages 711-730.
Crossref
Crossref
Duygu Kuzuoğlu-Öztürk, Eric Huntzinger, Steffen Schmidt & Elisa Izaurralde. (2012) The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Research 40:12, pages 5651-5665.
Crossref
Crossref
Christiane Harnisch, Bodo Moritz, Christiane Rammelt, Claudia Temme & Elmar Wahle. 2012. Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis, Part A. Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis, Part A
181
211
.
Joerg E. Braun, Eric Huntzinger, Maria Fauser & Elisa Izaurralde. (2011) GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets. Molecular Cell 44:1, pages 120-133.
Crossref
Crossref
Cathal McCannEimear E. HolohanSudeshna Das, Adrian DervanAoife LarkinJohn Anthony LeeVeronica Rodrigues, Roy Parker & Mani Ramaswami. (2011) The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation. Proceedings of the National Academy of Sciences 108:36.
Crossref
Crossref
Guangzuo Luo, Michael Costanzo, Charles Boone & Robert C. Dickson. (2011) Nutrients and the Pkh1/2 and Pkc1 Protein Kinases Control mRNA Decay and P-body Assembly in Yeast. Journal of Biological Chemistry 286:11, pages 8759-8770.
Crossref
Crossref
Chyi-Ying A. Chen & Ann-Bin Shyu. (2011) Mechanisms of deadenylation-dependent decay. Wiley Interdisciplinary Reviews: RNA 2:2, pages 167-183.
Crossref
Crossref
L X Garmire, ZhouXin Shen, S Briggs, Gene Yeo, S Subramaniam & C Glass. (2010) Regulatory network of microRNAs in RAW 264.7 macrophage cells. Regulatory network of microRNAs in RAW 264.7 macrophage cells.
Kylie D. Swisher & Roy Parker. (2010) Localization to, and Effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on Stress Granules in Saccharomyces cerevisiae. PLoS ONE 5:4, pages e10006.
Crossref
Crossref
Guennadi Kozlov, Nozhat Safaee, Angelika Rosenauer & Kalle Gehring. (2010) Structural Basis of Binding of P-body-associated Proteins GW182 and Ataxin-2 by the Mlle Domain of Poly(A)-binding Protein. Journal of Biological Chemistry 285:18, pages 13599-13606.
Crossref
Crossref
Guennadi Kozlov, Marie Ménade, Angelika Rosenauer, Long Nguyen & Kalle Gehring. (2010) Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein. Journal of Molecular Biology 397:2, pages 397-407.
Crossref
Crossref
Kouichi Ogami & Shinichi Hoshino. (2010) Research on mRNA degradation and drug discovery. Folia Pharmacologica Japonica 136:3, pages 150-154.
Crossref
Crossref
Vasupradha Vethantham & James L. Manley. 2009. SUMO Regulation of Cellular Processes. SUMO Regulation of Cellular Processes
41
57
.
Dinghai Zheng, Nader Ezzeddine, Chyi-Ying A. Chen, Wenmiao Zhu, Xiangwei He & Ann-Bin Shyu. (2008) Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells. The Journal of Cell Biology 182:1, pages 89-101.
Crossref
Crossref
Aaron C. Goldstrohm & Marvin Wickens. (2008) Multifunctional deadenylase complexes diversify mRNA control. Nature Reviews Molecular Cell Biology 9:4, pages 337-344.
Crossref
Crossref
Sundaresan Tharun. 2008.
149
189
.
Yuji Funakoshi, Yusuke Doi, Nao Hosoda, Naoyuki Uchida, Masanori Osawa, Ichio Shimada, Masafumi Tsujimoto, Tsutomu Suzuki, Toshiaki Katada & Shin-ichi Hoshino. (2007) Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases. Genes & Development 21:23, pages 3135-3148.
Crossref
Crossref
Ernesto Simón & Bertrand Séraphin. (2007) A specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decay. Nucleic Acids Research 35:18, pages 6017-6028.
Crossref
Crossref
Nadeem Siddiqui, David A. Mangus, Tsung-Cheng Chang, Jeanne-Marie Palermino, Ann-Bin Shyu & Kalle Gehring. (2007) Poly(A) Nuclease Interacts with the C-terminal Domain of Polyadenylate-binding Protein Domain from Poly(A)-binding Protein. Journal of Biological Chemistry 282:34, pages 25067-25075.
Crossref
Crossref
Audrey Perreault, Caroline Lemieux & François Bachand. (2007) Regulation of the Nuclear Poly(A)-binding Protein by Arginine Methylation in Fission Yeast. Journal of Biological Chemistry 282:10, pages 7552-7562.
Crossref
Crossref
Ida Stefanizzi & Rafaela Cañete-Soler. (2007) Coregulation of light neurofilament mRNA by poly(A)-binding protein and aldolase C: Implications for neurodegeneration. Brain Research 1139, pages 15-28.
Crossref
Crossref
Sonia Dheur, Keith R. Nykamp, Nicolas Viphakone, Maurice S. Swanson & Lionel Minvielle-Sebastia. (2005) Yeast mRNA Poly(A) Tail Length Control Can Be Reconstituted in Vitro in the Absence of Pab1p-dependent Poly(A) Nuclease Activity. Journal of Biological Chemistry 280:26, pages 24532-24538.
Crossref
Crossref
Markus Ralser, Mario Albrecht, Ute Nonhoff, Thomas Lengauer, Hans Lehrach & Sylvia Krobitsch. (2005) An Integrative Approach to Gain Insights into the Cellular Function of Human Ataxin-2. Journal of Molecular Biology 346:1, pages 203-214.
Crossref
Crossref
Ewan F. Dunn, Christopher M. Hammell, Christine A. Hodge & Charles N. Cole. (2005) Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export. Genes & Development 19:1, pages 90-103.
Crossref
Crossref