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Mammalian Genetic Models with Minimal or Complex Phenotypes

Capn5 Is Expressed in a Subset of T Cells and Is Dispensable for Development

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Pages 1649-1654 | Received 25 Sep 2003, Accepted 19 Nov 2003, Published online: 27 Mar 2023

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Nadia M. Randazzo$suffix/text()$suffix/text(), Morag E. Shanks$suffix/text()$suffix/text(), Penny Clouston$suffix/text()$suffix/text() & Robert E. MacLaren$suffix/text()$suffix/text(). (2019) Two Novel CAPN5 Variants Associated with Mild and Severe Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy Phenotypes. Ocular Immunology and Inflammation 27:5, pages 693-698.
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Vinit B Mahajan & Jonathan H Lin. (2013) Lymphocyte infiltration in CAPN5 autosomal dominant neovascular inflammatory vitreoretinopathy. Clinical Ophthalmology 7, pages 1339-1345.
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Articles from other publishers (14)

Simone Spinozzi, Sonia Albini, Heather Best & Isabelle Richard. (2021) Calpains for dummies: What you need to know about the calpain family. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1869:5, pages 140616.
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Yusaku Chukai, Takeshi Iwamoto, Ken Itoh, Hiroshi Tomita & Taku Ozaki. (2021) Characterization of mitochondrial calpain-5. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:5, pages 118989.
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Katherine J. Wert, Susanne F. Koch, Gabriel Velez, Chun‐Wei Hsu, MaryAnn Mahajan, Alexander G. Bassuk, Stephen H. Tsang & Vinit B. Mahajan. (2019) CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials . Human Mutation 40:12, pages 2377-2392.
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Cagney E. Coomer & Ann C. Morris. (2018) Capn5 Expression in the Healthy and Regenerating Zebrafish Retina. Investigative Opthalmology & Visual Science 59:8, pages 3643.
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Yasuko Ono, Takaomi C. Saido & Hiroyuki Sorimachi. (2016) Calpain research for drug discovery: challenges and potential. Nature Reviews Drug Discovery 15:12, pages 854-876.
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Lokesh Gakhar, Alexander G. Bassuk, Gabriel Velez, Saif Khan, Jing Yang, Stephen H. Tsang & Vinit B. Mahajan. (2016) Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains. Journal of Structural Biology 196:3, pages 309-318.
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Yasuko Ono, Koichi Ojima, Fumiko Shinkai-Ouchi, Shoji Hata & Hiroyuki Sorimachi. (2016) An eccentric calpain, CAPN3/p94/calpain-3. Biochimie 122, pages 169-187.
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Alexander G. Bassuk, Steven Yeh, Shu Wu, Daniel F. Martin, Stephen H. Tsang, Lokesh Gakhar & Vinit B. Mahajan. (2015) Structural Modeling of a Novel CAPN5 Mutation that Causes Uveitis and Neovascular Retinal Detachment. PLOS ONE 10:4, pages e0122352.
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Samuel M. Peterson & Jennifer L. Freeman. (2014) Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression. Advances in Toxicology 2014, pages 1-13.
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Ranjana Singh, M.Kathryn Brewer, Charles B. Mashburn, Dingyuan Lou, Vimala Bondada, Brantley Graham & James W. Geddes. (2014) Calpain 5 Is Highly Expressed in the Central Nervous System (CNS), Carries Dual Nuclear Localization Signals, and Is Associated with Nuclear Promyelocytic Leukemia Protein Bodies. Journal of Biological Chemistry 289:28, pages 19383-19394.
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Kazuo Tonami, Shoji Hata, Koichi Ojima, Yasuko Ono, Yukiko Kurihara, Tomokazu Amano, Takahiro Sato, Yumiko Kawamura, Hiroki Kurihara & Hiroyuki Sorimachi. (2013) Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration. PLoS Genetics 9:8, pages e1003668.
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Hiroyuki SORIMACHI, Shoji HATA & Yasuko ONO. (2011) Calpain chronicle—an enzyme family under multidisciplinary characterization. Proceedings of the Japan Academy, Series B 87:6, pages 287-327.
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Hiroyuki SORIMACHIShoji HATAYasuko ONO. (2010) Expanding Members and Roles of the Calpain Superfamily and Their Genetically Modified Animals. Experimental Animals 59:5, pages 549-566.
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S. F. Larner, R. L. Hayes & K. K. W. Wang. 2009. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 249 279 .

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