Advanced search
Publication Cover
Molecular and Cellular Biology Volume 25, 2005 - Issue 1
Submit an article Journal homepage
59
Views
54
CrossRef citations to date
0
Altmetric
Signal Transduction

Vascular Endothelial Growth Factor A (VEGF-A) Is Involved in Guidance of VEGF Receptor-Positive Cells to the Anterior Portion of Early Embryos

Sachie Hiratsuka1 Department of Genetics;2 Department of Pharmacology
,
Yuki Kataoka3 Laboratory of Gene Expression and Regulation, Institute of Medical Science
,
Kazuki Nakao4 Laboratory for Animal Resource and Genetic Engineering, RIKEN, Center for Developmental Biology, Hyogo
,
Kenji Nakamura5 Reproductive Engineering Section, Mouse Genome Technology Center, Mitsubishi Kagaku Institute of Life Science, Tokyo
,
Shunichi Morikawa6 Department of Anatomy & Developmental Biology, Tokyo Women's Medical University School of Medicine
,
Satoshi Tanaka7 Laboratory of Cellular Biochemistry, Animal Resource Science/Veterinary Medical Science, University of Tokyo
,
Motoya Katsuki8 National Institute for Basic Biology, Aichi, Japan
,
Yoshiro Maru2 Department of Pharmacology
&
Masabumi Shibuya1 Department of GeneticsCorrespondence[email protected]
 show all
Pages 355-363 | Received 27 Jun 2004, Accepted 04 Oct 2004, Published online: 27 Mar 2023

Citations (54)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Jody J. Haigh. (2008) Role of VEGF in organogenesis. Organogenesis 4:4, pages 247-256.
Read now
Masabumi Shibuya. (2006) Vascular Endothelial Growth Factor (VEGF)-Receptor2: Its Biological Functions, Major Signaling Pathway, and Specific Ligand VEGF-E. Endothelium 13:2, pages 63-69.
Read now

Articles from other publishers (52)

Takashi Ueda, Masaya Watanabe, Youko Miwa, Yasuhiro Shibata, Natsuko Kumamoto & Shinya Ugawa. (2023) Vascular endothelial growth factor-A is involved in intramuscular carrageenan-induced cutaneous mechanical hyperalgesia through the vascular endothelial growth factor-A receptor 1 and transient receptor potential vanilloid 1 pathways. NeuroReport 34:4, pages 238-248.
Crossref
Krishna Latha, Sanjana Rao, Kaori Sakamoto & Wendy T. Watford. (2022) Tumor Progression Locus 2 Protects against Acute Respiratory Distress Syndrome in Influenza A Virus-Infected Mice. Microbiology Spectrum 10:5.
Crossref
I. Tekin & F. Kosova. (2022) The level pro-inflammatory and anti-inflammatory biomarkers in patients with chronic mechanical low back pain under pulse radiofrequency therapy. The Ukrainian Biochemical Journal 94:3, pages 59-67.
Crossref
Bronte Miller & Mary Kathryn Sewell-Loftin. (2022) Mechanoregulation of Vascular Endothelial Growth Factor Receptor 2 in Angiogenesis. Frontiers in Cardiovascular Medicine 8.
Crossref
C. Collart, A. Ciccarelli, K. Ivanovitch, I. Rosewell, S. Kumar, G. Kelly, A. Edwards & J. C. Smith. (2021) The migratory pathways of the cells that form the endocardium, dorsal aortae, and head vasculature in the mouse embryo. BMC Developmental Biology 21:1.
Crossref
Graham Rykiel, MacKenzie Gray, Brenda Rongish & Sandra Rugonyi. (2021) Transient increase in VEGF‐A leads to cardiac tube anomalies and increased risk of congenital heart malformations . The Anatomical Record 304:12, pages 2685-2702.
Crossref
Hong Zeng, Lian Hu, Hebin Xie, Wenmin Ma & Song Quan. (2021) Polymorphisms of vascular endothelial growth factor and recurrent implantation failure: a systematic review and meta-analysis. Archives of Gynecology and Obstetrics 304:2, pages 297-307.
Crossref
Hong Zeng, Dongmei He, Hebin Xie, Yuhao Zhao, Zhaoqun Peng, Huan Deng, Jinyue Hu, Binyuan Jiang & Nenghui Liu. (2020) H19 regulates angiogenic capacity of extravillous trophoblasts by H19/miR-106a-5p/VEGFA axis. Archives of Gynecology and Obstetrics 301:3, pages 671-679.
Crossref
Jeong Yong Lee, Eun Hee Ahn, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Ji Hyang Kim, Young Ran Kim, Woo Sik Lee & Nam Keun Kim. (2019) Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women. Human Genomics 13:1.
Crossref
Yosef Laviv, Joshua L. Wang, Matthew P. Anderson & Ekkehard M. Kasper. (2017) Accelerated growth of hemangioblastoma in pregnancy: the role of proangiogenic factors and upregulation of hypoxia-inducible factor (HIF) in a non-oxygen-dependent pathway. Neurosurgical Review 42:2, pages 209-226.
Crossref
Wenjing Xu, Minglu Liang, Yanqing Zhang, Kai Huang & Cheng Wang. (2019) Endothelial FAM3A positively regulates post-ischaemic angiogenesis. EBioMedicine 43, pages 32-42.
Crossref
Zarius Ferozepurwalla, Jude Merzah, Lieze Thielemans & Graeme Birdsey. 2019. Heart of the Matter. Heart of the Matter 219 226 .
Nathaniel Lal, Karanjit Puri & Brian Rodrigues. (2018) Vascular Endothelial Growth Factor B and Its Signaling. Frontiers in Cardiovascular Medicine 5.
Crossref
Aneta Zwierzchowska, Anna Iwan, Anna Hyc, Barbara Suchońska, Jacek Malejczyk & Ewa Barcz. (2018) Recurrent miscarriage is associated with increased ghrelin mRNA expression in the endometrium- a case-control study. Reproductive Biology 18:1, pages 12-17.
Crossref
X. Shi, X. Xie, Y. Jia & S. Li. (2017) Maternal genetic polymorphisms and unexplained recurrent miscarriage: a systematic review and meta-analysis. Clinical Genetics 91:2, pages 265-284.
Crossref
Xiaocai Yan, Elizabeth Managlia, Shirley XL Liu, Xiao-Di Tan, Xiao Wang, Catherine Marek & Isabelle G. De Plaen. (2016) Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice. American Journal of Physiology-Gastrointestinal and Liver Physiology 310:9, pages G716-G725.
Crossref
Yulia O. Kipryushina, Konstantin V. Yakovlev & Nelly A. Odintsova. (2015) Vascular endothelial growth factors: A comparison between invertebrates and vertebrates. Cytokine & Growth Factor Reviews 26:6, pages 687-695.
Crossref
F. Semeraro, A. Cancarini, R. dell’Omo, S. Rezzola, M. R. Romano & C. Costagliola. (2015) Diabetic Retinopathy: Vascular and Inflammatory Disease. Journal of Diabetes Research 2015, pages 1-16.
Crossref
Mei-Tsz Su, Sheng-Hsiang Lin, Yi-Chi Chen & Pao-Lin Kuo. (2014) Gene-gene interactions and gene polymorphisms of VEGFA and EG-VEGF gene systems in recurrent pregnancy loss. Journal of Assisted Reproduction and Genetics 31:6, pages 699-705.
Crossref
W. Y. Almawi, F. L. Saldanha, N. A. Mahmood, I. Al-Zaman, M. S. Sater & F. E. Mustafa. (2013) Relationship between VEGFA polymorphisms and serum VEGF protein levels and recurrent spontaneous miscarriage. Human Reproduction 28:10, pages 2628-2635.
Crossref
Andras Czirok. (2013) Endothelial cell motility, coordination and pattern formation during vasculogenesis. WIREs Systems Biology and Medicine 5:5, pages 587-602.
Crossref
Evangelia Pardali, Rinesh Godfrey & Johannes Waltenberger. 2013. Tumor Angiogenesis Regulators. Tumor Angiogenesis Regulators 1 36 .
HyungChul Rah, Young Joo Jeon, Bo Eun Lee, Dong Hee Choi, Tae Ki Yoon, Woo Sik Lee & Nam Keun Kim. (2013) Association of kinase insert domain-containing receptor (KDR) gene polymorphisms with idiopathic recurrent spontaneous abortion in Korean women. Fertility and Sterility 99:3, pages 753-760.e8.
Crossref
Roberto dell'Omo, Francesco Semeraro, Giulio Bamonte, Francesco Cifariello, Mario R. Romano & Ciro Costagliola. (2013) Vitreous Mediators in Retinal Hypoxic Diseases. Mediators of Inflammation 2013, pages 1-16.
Crossref
Bingzhen Zhang, Bingqin Dai, Xingliang Zhang & Zhiping Wang. (2012) Vascular endothelial growth factor and recurrent spontaneous abortion: A meta-analysis. Gene 507:1, pages 1-8.
Crossref
Mei-Tsz Su, Sheng-Hsiang Lin & Yi-Chi Chen. (2011) Genetic association studies of angiogenesis- and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Human Reproduction Update 17:6, pages 803-812.
Crossref
Feng-Jen Tseng, Yen-Ku Liu, Yo-Shong Chung, Yu-Ling Lin, Chia-Hung Chen, Wan-Yi Wang, Yu-Cheng Chen, Nu-Man Tsai, Tian-Lu Cheng, Ru-Yu Pan, Tsung-Ming Hu, Ru-Ping Lee & Kuang-Wen Liao. (2011) A fusion protein composed of receptor binding domain of vascular endothelial growth factor-A and constant region fragment of antibody: angiogenesis antagonistic activity. Cytotechnology 63:3, pages 285-293.
Crossref
Ting He, Nataliya Smith, Debra Saunders, Sabrina Doblas, Yasuko Watanabe, Jessica Hoyle, Robert Silasi-Mansat, Florea Lupu, Megan Lerner, Daniel J. Brackett & Rheal A. Towner. (2011) Molecular MRI assessment of vascular endothelial growth factor receptor-2 in rat C6 gliomas. Journal of Cellular and Molecular Medicine 15:4, pages 837-849.
Crossref
Mei-Tsz Su, Sheng-Hsiang Lin, I-Wen Lee, Yi-Chi Chen & Pao-Lin Kuo. (2011) Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss. Human Reproduction 26:4, pages 758-764.
Crossref
Wilma D. Perez, Crystal R. Weller, Siming Shou & H. Scott Stadler. (2010) Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development. Developmental Dynamics 239:2, pages 446-457.
Crossref
Iris Appelmann, Rüediger Liersch, Torsten Kessler, Rolf M. Mesters & Wolfgang E. Berdel. 2010. Angiogenesis Inhibition. Angiogenesis Inhibition 51 81 .
Yureeda Qazi, Surekha Maddula & Balamurali K. Ambati. (2009) Mediators of ocular angiogenesis. Journal of Genetics 88:4, pages 495-515.
Crossref
Q. Guo, J. J. Carrero, X. Yu, P. Barany, A. R. Qureshi, M. Eriksson, B. Anderstam, M. Chmielewski, O. Heimburger, P. Stenvinkel, B. Lindholm & J. Axelsson. (2009) Associations of VEGF and its receptors sVEGFR-1 and -2 with cardiovascular disease and survival in prevalent haemodialysis patients. Nephrology Dialysis Transplantation 24:11, pages 3468-3473.
Crossref
Hitoshi Sase, Tetsuro Watabe, Kyoko Kawasaki, Kohei Miyazono & Keiji Miyazawa. (2009) VEGFR2-PLCγ1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells. Journal of Cell Science 122:18, pages 3303-3311.
Crossref
Beth A. Tamburini, Susan Trapp, Tzu Lip Phang, Jill T. Schappa, Lawrence E. Hunter & Jaime F. Modiano. (2009) Gene Expression Profiles of Sporadic Canine Hemangiosarcoma Are Uniquely Associated with Breed. PLoS ONE 4:5, pages e5549.
Crossref
Kyu Yeon Han, Chan Woo Kim, Tae Hoon Lee, Youngsook Son & Jiyoung Kim. (2009) CCL23 up-regulates expression of KDR/Flk-1 and potentiates VEGF-induced proliferation and migration of human endothelial cells. Biochemical and Biophysical Research Communications 382:1, pages 124-128.
Crossref
S. Kalkunte, Z. Lai, N. Tewari, C. Chichester, R. Romero, J. Padbury & S. Sharma. (2008) In Vitro and In Vivo Evidence for Lack of Endovascular Remodeling by Third Trimester Trophoblasts. Placenta 29:10, pages 871-878.
Crossref
Joakim Janér, Sture Andersson, Caj Haglund, Riitta Karikoski & Patrik Lassus. (2008) Placental Growth Factor and Vascular Endothelial Growth Factor Receptor-2 in Human Lung Development. Pediatrics 122:2, pages 340-346.
Crossref
Kyoko Kawasaki, Tetsuro Watabe, Hitoshi Sase, Masanori Hirashima, Hiroshi Koide, Yasuyuki Morishita, Keiko Yuki, Toshikuni Sasaoka, Toshio Suda, Motoya Katsuki, Kohei Miyazono & Keiji Miyazawa. (2008) Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. Journal of Cell Biology 181:1, pages 131-141.
Crossref
Jody J. Haigh. 2008. VEGF in Development. VEGF in Development 52 67 .
Nathan BaharyKatsutoshi Goishi, Carsten StuckenholzGerhard Weber, Jocelyn LeBlanc, Christopher A. SchaferSarah S. BermanMichael Klagsbrun & Leonard I. Zon. (2007) Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood 110:10, pages 3627-3636.
Crossref
Annette SchmidtKlara BrixiusWilhelm Bloch. (2007) Endothelial Precursor Cell Migration During Vasculogenesis. Circulation Research 101:2, pages 125-136.
Crossref
Louise DuloquinGuy LhomondChristian Gache. (2007) Localized VEGF signaling from ectoderm to mesenchyme cells controls morphogenesis of the sea urchin embryo skeleton. Development 134:12, pages 2293-2302.
Crossref
Hirokazu Hirata, Shin Kawamata, Yoshinobu Murakami, Kayoko Inoue, Ayako Nagahashi, Mako Tosaka, Naoko Yoshimura, Yoshiaki Miyamoto, Hiroto Iwasaki, Takayuki Asahara & Yoshiki Sawa. (2007) Coexpression of platelet-derived growth factor receptor alpha and fetal liver kinase 1 enhances cardiogenic potential in embryonic stem cell differentiation in vitro. Journal of Bioscience and Bioengineering 103:5, pages 412-419.
Crossref
Xiong-Zhi Wu & Xiao-Hui Yu. (2007) Bone marrow cells: The source of hepatocellular carcinoma?. Medical Hypotheses 69:1, pages 36-42.
Crossref
Volker Hartenstein. (2006) Blood Cells and Blood Cell Development in the Animal Kingdom. Annual Review of Cell and Developmental Biology 22:1, pages 677-712.
Crossref
Masabumi Shibuya. (2006) Differential Roles of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Angiogenesis. BMB Reports 39:5, pages 469-478.
Crossref
Dirk Dormann & Cornelis J Weijer. (2006) Chemotactic cell movement during Dictyostelium development and gastrulation. Current Opinion in Genetics & Development 16:4, pages 367-373.
Crossref
Bradford P. Mallory, Timothy J. Mead, Diane A.F. Wiginton, Rishikesh M. Kulkarni, James M. Greenberg & Ann L. Akeson. (2006) Lymphangiogenesis in the developing lung promoted by VEGF-A. Microvascular Research 72:1-2, pages 62-73.
Crossref
Anna-Karin Olsson, Anna Dimberg, Johan Kreuger & Lena Claesson-Welsh. (2006) VEGF receptor signalling ? in control of vascular function. Nature Reviews Molecular Cell Biology 7:5, pages 359-371.
Crossref
Masabumi Shibuya & Lena Claesson-Welsh. (2006) Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Experimental Cell Research 312:5, pages 549-560.
Crossref
A. M. Suburo & P. A. D’Amore. 2006. The Vascular Endothelium I. The Vascular Endothelium I 71 105 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.