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Molecular and Cellular Biology Volume 25, 2005 - Issue 11
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Chromosome Structure and Dynamics

Biological and Biochemical Functions of RNA in the Tetrahymena Telomerase Holoenzyme

Doreen D. CunninghamDepartment of Molecular and Cell Biology, University of California, Berkeley, California
&
Kathleen CollinsDepartment of Molecular and Cell Biology, University of California, Berkeley, CaliforniaCorrespondence[email protected]
Pages 4442-4454 | Received 02 Feb 2005, Accepted 08 Mar 2005, Published online: 27 Mar 2023

Citations (28)

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Timothy M. Errington, Dragony Fu, Judy M. Y. Wong & Kathleen Collins. (2008) Disease-Associated Human Telomerase RNA Variants Show Loss of Function for Telomere Synthesis without Dominant-Negative Interference. Molecular and Cellular Biology 28:20, pages 6510-6520.
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Keren L. Witkin, Ramadevi Prathapam & Kathleen Collins. (2007) Positive and Negative Regulation of Tetrahymena Telomerase Holoenzyme. Molecular and Cellular Biology 27:6, pages 2074-2083.
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Articles from other publishers (26)

Abhishek Dey, Anais Monroy-Eklund, Kaitlin Klotz, Arpita Saha, Justin Davis, Bibo Li, Alain Laederach & Kausik Chakrabarti. (2021) In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei . Nucleic Acids Research 49:21, pages 12445-12466.
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Petra Procházková Schrumpfová & Jiří Fajkus. (2020) Composition and Function of Telomerase—A Polymerase Associated with the Origin of Eukaryotes. Biomolecules 10:10, pages 1425.
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Aishwarya P Deshpande & Kathleen Collins. (2018) Mechanisms of template handling and pseudoknot folding in human telomerase and their manipulation to expand the sequence repertoire of processive repeat synthesis. Nucleic Acids Research 46:15, pages 7886-7901.
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Darian D. Cash & Juli Feigon. (2017) Structure and folding of the Tetrahymena telomerase RNA pseudoknot . Nucleic Acids Research 45:1, pages 482-495.
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Linnea I Jansson, Ben M Akiyama, Alexandra Ooms, Cheng Lu, Seth M Rubin & Michael D Stone. (2015) Structural basis of template-boundary definition in Tetrahymena telomerase. Nature Structural & Molecular Biology 22:11, pages 883-888.
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Robert Alexander Wu, Yavuz S Dagdas, S Tunc Yilmaz, Ahmet Yildiz & Kathleen Collins. (2015) Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes. eLife 4.
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Edward J Miracco, Jiansen Jiang, Darian D Cash & Juli Feigon. (2014) Progress in structural studies of telomerase. Current Opinion in Structural Biology 24, pages 115-124.
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Michael Harkisheimer, Mark Mason, Elena Shuvaeva & Emmanuel Skordalakes. (2013) A Motif in the Vertebrate Telomerase N-Terminal Linker of TERT Contributes to RNA Binding and Telomerase Activity and Processivity. Structure 21:10, pages 1870-1878.
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Jiansen Jiang, Edward J. Miracco, Kyungah Hong, Barbara Eckert, Henry Chan, Darian D. Cash, Bosun Min, Z. Hong Zhou, Kathleen Collins & Juli Feigon. (2013) The architecture of Tetrahymena telomerase holoenzyme. Nature 496:7444, pages 187-192.
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Daud I. Cole, Jason D. Legassie, Laura N. Bonifacio, Vijay G. Sekaran, Feng Ding, Nikolay V. Dokholyan & Michael B. Jarstfer. (2012) New Models of Tetrahymena Telomerase RNA from Experimentally Derived Constraints and Modeling. Journal of the American Chemical Society 134:49, pages 20070-20080.
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Emily D. Egan & Kathleen Collins. (2012) Biogenesis of telomerase ribonucleoproteins. RNA 18:10, pages 1747-1759.
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Mahavir Singh, Zhonghua Wang, Bon-Kyung Koo, Anooj Patel, Duilio Cascio, Kathleen Collins & Juli Feigon. (2012) Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Molecular Cell 47:1, pages 16-26.
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Yehuda Tzfati & Julian J.‐L. Chen. 2012. Telomerases. Telomerases 23 51 .
Barbara Eckert & Kathleen Collins. (2012) Roles of Telomerase Reverse Transcriptase N-terminal Domain in Assembly and Activity of Tetrahymena Telomerase Holoenzyme. Journal of Biological Chemistry 287:16, pages 12805-12814.
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Kathleen Collins. (2011) Single-stranded DNA repeat synthesis by telomerase. Current Opinion in Chemical Biology 15:5, pages 643-648.
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Vijay G. Sekaran, Joana Soares & Michael B. Jarstfer. (2010) Structures of telomerase subunits provide functional insights. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1804:5, pages 1190-1201.
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Aaron R. Robart, Catherine M. O'Connor & Kathleen Collins. (2010) Ciliate telomerase RNA loop IV nucleotides promote hierarchical RNP assembly and holoenzyme stability. RNA 16:3, pages 563-571.
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Bosun Min & Kathleen Collins. (2009) An RPA-Related Sequence-Specific DNA-Binding Subunit of Telomerase Holoenzyme Is Required for Elongation Processivity and Telomere Maintenance. Molecular Cell 36:4, pages 609-619.
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Kathleen Collins. 2009. Non-Protein Coding RNAs. Non-Protein Coding RNAs 285 301 .
Susan Rouda & Emmanuel Skordalakes. (2007) Structure of the RNA-Binding Domain of Telomerase: Implications for RNA Recognition and Binding. Structure 15:11, pages 1403-1412.
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Nikolai B. Ulyanov, Kinneret Shefer, Thomas L. James & Yehuda Tzfati. (2007) Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Research 35:18, pages 6150-6160.
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Neal F. Lue & Zhaohui Li. (2007) Modeling and structure function analysis of the putative anchor site of yeast telomerase. Nucleic Acids Research 35:15, pages 5213-5222.
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Erez Romi, Nava Baran, Marina Gantman, Michael Shmoish, Bosun Min, Kathleen Collins & Haim Manor. (2007) High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase. Proceedings of the National Academy of Sciences 104:21, pages 8791-8796.
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Michael D. Stone, Mariana Mihalusova, Catherine M. O’Connor, Ramadevi Prathapam, Kathleen Collins & Xiaowei Zhuang. (2007) Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein. Nature 446:7134, pages 458-461.
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Kathleen Collins. (2006) The biogenesis and regulation of telomerase holoenzymes. Nature Reviews Molecular Cell Biology 7:7, pages 484-494.
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Carla A Theimer & Juli Feigon. (2006) Structure and function of telomerase RNA. Current Opinion in Structural Biology 16:3, pages 307-318.
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