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Elias A. Tannous & Peter M. Burgers. (2021) Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM). Critical Reviews in Biochemistry and Molecular Biology 56:5, pages 441-454.
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Lorraine S. Symington. (2016) Mechanism and regulation of DNA end resection in eukaryotes. Critical Reviews in Biochemistry and Molecular Biology 51:3, pages 195-212.
Read now
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Wilson C. Y. Lau, Yinyin Li, Zhe Liu, Yuanzhu Gao, Qinfen Zhang & Michael S. Y. Huen. (2016) Structure of the human dimeric ATM kinase. Cell Cycle 15:8, pages 1117-1124.
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Corey Helchowski, Laura Skow, Katelyn Roberts, Colleen Chute & Christine Canman. (2013) A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci. Cell Cycle 12:24, pages 3749-3758.
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Yun-Hsin Cheng, Chi-Ning Chuang, Hui-Ju Shen, Feng-Ming Lin & Ting-Fang Wang. (2013) Three Distinct Modes of Mec1/ATR and Tel1/ATM Activation Illustrate Differential Checkpoint Targeting during Budding Yeast Early Meiosis. Molecular and Cellular Biology 33:16, pages 3365-3376.
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Peter Botev, George Russev, Boyka Anachkova & Anastas Gospodinov. (2013) Structural Aspects of Double Strand Break Repair. Biotechnology & Biotechnological Equipment 27:1, pages 3485-3492.
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Kate Beishline, Crystal M. Kelly, Beatrix A. Olofsson, Sravanthi Koduri, Jacqueline Emrich, Roger A. Greenberg & Jane Azizkhan-Clifford. (2012) Sp1 Facilitates DNA Double-Strand Break Repair through a Nontranscriptional Mechanism. Molecular and Cellular Biology 32:18, pages 3790-3799.
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Sanjay Kumar, Hae Yong Yoo, Akiko Kumagai, Anna Shevchenko, Andrej Shevchenko & William G. Dunphy. (2012) Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts. Cell Cycle 11:6, pages 1183-1194.
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Natsuko Izumi, Akio Yamashita & Shigeo Ohno. (2012) Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2. Nucleus 3:1, pages 29-43.
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Jennifer S. Gewandter, Robert A. Bambara & Michael A. O’Reilly. (2011) The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA. Cell Cycle 10:15, pages 2561-2567.
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Kenzo Fukunaga, Youngho Kwon, Patrick Sung & Katsunori Sugimoto. (2011) Activation of Protein Kinase Tel1 through Recognition of Protein-Bound DNA Ends. Molecular and Cellular Biology 31:10, pages 1959-1971.
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Minori Dateki, Megumi Kunitomo, Kento Yoshioka, Kazuyuki Yanai, Satoshi Nakasono & Tadashi Negishi. (2011) Adaptive gene regulation of pyruvate dehydrogenase kinase isoenzyme 4 in hepatotoxic chemical-induced liver injury and its stimulatory potential for DNA repair and cell proliferation. Journal of Receptors and Signal Transduction 31:1, pages 85-95.
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Oliver Limbo, Mary E. Porter-Goff, Nicholas Rhind & Paul Russell. (2011) Mre11 Nuclease Activity and Ctp1 Regulate Chk1 Activation by Rad3ATR and Tel1ATM Checkpoint Kinases at Double-Strand Breaks. Molecular and Cellular Biology 31:3, pages 573-583.
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Serah Choi, Armin M. Gamper, Jason S. White & Christopher J. Bakkenist. (2010)
Inhibition of ATM kinase activity does not phenocopy ATM protein disruption. Cell Cycle 9:20, pages 4052-4057.
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Elias A. Rahal, Leigh A. Henricksen, Yuling Li, R. Scott Williams, John A. Tainer & Kathleen Dixon. (2010) ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining. Cell Cycle 9:14, pages 2938-2949.
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Ashok R. Venkitaraman. (2010) Modifying chromatin architecture during the response to DNA breakage. Critical Reviews in Biochemistry and Molecular Biology 45:1, pages 2-13.
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Christine S. Vissinga, Tiong C. Yeo, Sarah Warren, James V. Brawley, Jennifer Phillips, Karen Cerosaletti & Patrick Concannon. (2009) Nuclear Export of NBN Is Required for Normal Cellular Responses to Radiation. Molecular and Cellular Biology 29:4, pages 1000-1006.
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Travis H. Stracker, Bret R. Williams, Ludovic Deriano, Jan W. Theunissen, Carrie A. Adelman, David B. Roth & John H. J. Petrini. (2009) Artemis and Nonhomologous End Joining-Independent Influence of DNA-Dependent Protein Kinase Catalytic Subunit on Chromosome Stability. Molecular and Cellular Biology 29:2, pages 503-514.
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Jeffrey J. Seidel, Carol M. Anderson & Elizabeth H. Blackburn. (2008) A Novel Tel1/ATM N-Terminal Motif, TAN, Is Essential for Telomere Length Maintenance and a DNA Damage Response. Molecular and Cellular Biology 28:18, pages 5736-5746.
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Yufuko Akamatsu, Yasuto Murayama, Takatomi Yamada, Tomofumi Nakazaki, Yasuhiro Tsutsui, Kunihiro Ohta & Hiroshi Iwasaki. (2008) Molecular Characterization of the Role of the Schizosaccharomyces pombe nip1+/ctp1+ Gene in DNA Double-Strand Break Repair in Association with the Mre11-Rad50-Nbs1 Complex. Molecular and Cellular Biology 28:11, pages 3639-3651.
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Julie M. Bailis, Douglas D. Luche, Tony Hunter & Susan L. Forsburg. (2008) Minichromosome Maintenance Proteins Interact with Checkpoint and Recombination Proteins To Promote S-Phase Genome Stability. Molecular and Cellular Biology 28:5, pages 1724-1738.
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Lakxmi Subramanian, Bettina A. Moser & Toru M. Nakamura. (2008) Recombination-Based Telomere Maintenance Is Dependent on Tel1-MRN and Rap1 and Inhibited by Telomerase, Taz1, and Ku in Fission Yeast. Molecular and Cellular Biology 28:5, pages 1443-1455.
Read now
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Dimitry A. Chistiakov, Natalia V. Voronova & Pavel A. Chistiakov. (2008) Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients. Acta Oncologica 47:5, pages 809-824.
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Yingli Sun, Ye Xu, Kanaklata Roy & Brendan D. Price. (2007) DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity. Molecular and Cellular Biology 27:24, pages 8502-8509.
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Aimin Peng, Andrea L. Lewellyn & James L. Maller. (2007) Undamaged DNA Transmits and Enhances DNA Damage Checkpoint Signals in Early Embryos. Molecular and Cellular Biology 27:19, pages 6852-6862.
Read now
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Gary P. H. Ho, Steven Margossian, Toshiyasu Taniguchi & Alan D. D'Andrea. (2006) Phosphorylation of FANCD2 on Two Novel Sites Is Required for Mitomycin C Resistance. Molecular and Cellular Biology 26:18, pages 7005-7015.
Read now
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Paris Petersen, Danny M. Chou, Zhongsheng You, Tony Hunter, Johannes C. Walter & Gernot Walter. (2006) Protein Phosphatase 2A Antagonizes ATM and ATR in a Cdk2- and Cdc7-Independent DNA Damage Checkpoint. Molecular and Cellular Biology 26:5, pages 1997-2011.
Read now
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Karen Cerosaletti, Jocyndra Wright & Patrick Concannon. (2006) Active Role for Nibrin in the Kinetics of Atm Activation. Molecular and Cellular Biology 26:5, pages 1691-1699.
Read now
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Gang Liu & Xinbin Chen. (2006) DNA Polymerase η, the Product of the Xeroderma Pigmentosum Variant Gene and a Target of p53, Modulates the DNA Damage Checkpoint and p53 Activation. Molecular and Cellular Biology 26:4, pages 1398-1413.
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Crossref
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Karl-Peter Hopfner. (2023) Mre11–Rad50: the DNA end game. Biochemical Society Transactions 51:2, pages 527-538.
Crossref
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Linah A. Shahoumi, Muhammad H. A. Saleh & Mohamed M. Meghil. (2023) Virulence Factors of the Periodontal Pathogens: Tools to Evade the Host Immune Response and Promote Carcinogenesis. Microorganisms 11:1, pages 115.
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Crossref
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Crossref
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Crossref
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Lea A. R. Fabry & Antigoni Triantafyllopoulou. (2022) Der Rolle der DNA-Schadensantwort bei granulomatösen ErkrankungenThe role of the response to DNA damage in granulomatous diseases. Zeitschrift für Rheumatologie 81:10, pages 881-887.
Crossref
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Crossref
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Crossref
Crossref
Jake A. Kloeber & Zhenkun Lou. (2022) Critical DNA damaging pathways in tumorigenesis. Seminars in Cancer Biology 85, pages 164-184.
Crossref
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Paolo Pizzul, Erika Casari, Marco Gnugnoli, Carlo Rinaldi, Flavio Corallo & Maria Pia Longhese. (2022) The DNA damage checkpoint: A tale from budding yeast. Frontiers in Genetics 13.
Crossref
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Jeffrey Lynham & Walid A. Houry. (2022) The Role of Hsp90-R2TP in Macromolecular Complex Assembly and Stabilization. Biomolecules 12:8, pages 1045.
Crossref
Crossref
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Crossref
Crossref
Christopher Warren & Nikola P Pavletich. (2022) Structure of the human ATM kinase and mechanism of Nbs1 binding. eLife 11.
Crossref
Crossref
Johanna Kliche & Ylva Ivarsson. (2022) Orchestrating serine/threonine phosphorylation and elucidating downstream effects by short linear motifs. Biochemical Journal 479:1, pages 1-22.
Crossref
Crossref
Agnieszka Panek & Justyna Miszczyk. (2021) ATM and RAD51 Repair Pathways in Human Lymphocytes Irradiated with 70 MeV Therapeutic Proton Beam. Radiation Research 197:4.
Crossref
Crossref
Mariarosaria De Falco & Mariarita De Felice. (2021) Take a Break to Repair: A Dip in the World of Double-Strand Break Repair Mechanisms Pointing the Gaze on Archaea. International Journal of Molecular Sciences 22:24, pages 13296.
Crossref
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Crossref
Crossref
Rhys M. Williams & Xiaodong Zhang. (2021) Roles of ATM and ATR in DNA double strand breaks and replication stress. Progress in Biophysics and Molecular Biology 163, pages 109-119.
Crossref
Crossref
Marijke Jansma & Karl-Peter Hopfner. (2021) Structural basis of the (in)activity of the apical DNA damage response kinases ATM, ATR and DNA-PKcs. Progress in Biophysics and Molecular Biology 163, pages 120-129.
Crossref
Crossref
Jianxiong Xiao, Qinhui Rao & Yanhui Xu. (2021) The activation mechanisms of master kinases in the DNA damage response. Genome Instability & Disease 2:4, pages 211-224.
Crossref
Crossref
Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka & Alessandro Bianchi. (2021) Inhibition of MRN activity by a telomere protein motif. Nature Communications 12:1.
Crossref
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Christine J. Hawkins & Mark A. Miles. (2021) Mutagenic Consequences of Sublethal Cell Death Signaling. International Journal of Molecular Sciences 22:11, pages 6144.
Crossref
Crossref
Rhys M. Williams & Xiaodong Zhang. (2021) Roles of ATM and ATR in DNA double strand breaks and replication stress. Progress in Biophysics and Molecular Biology 161, pages 27-38.
Crossref
Crossref
Erik Waskiewicz, Michalis Vasiliou, Isaac Corcoles-Saez & Rita S. Cha. (2021) Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis. Communications Biology 4:1.
Crossref
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Max E. Mertens & David M. Knipe. (2021) Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses. mBio 12:1.
Crossref
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Scott Baughan & Michael A. Tainsky. (2021) K3326X and Other C-Terminal BRCA2 Variants Implicated in Hereditary Cancer Syndromes: A Review. Cancers 13:3, pages 447.
Crossref
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Nazanin K Majd, Timothy A Yap, Dimpy Koul, Veerakumar Balasubramaniyan, Xiaolong Li, Sabbir Khan, Katilin S Gandy, W K Alfred Yung & John F de Groot. (2021) The promise of DNA damage response inhibitors for the treatment of glioblastoma. Neuro-Oncology Advances 3:1.
Crossref
Crossref
Anuradha Nair, Vinayaki S. Pillai & Rajani Kant Chittela. (2021) Characterization of the N- terminal domain of Mre11 protein from rice (OsMre11) Oryza sativa. Plant Science 302, pages 110730.
Crossref
Crossref
Fei Zhao, Wootae Kim, Jake A. Kloeber & Zhenkun Lou. (2020) DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells. Experimental & Molecular Medicine 52:10, pages 1705-1714.
Crossref
Crossref
Kaishun Hu, Yu Li, Wenjing Wu, Limin Xie, Haiyan Yan, Yuexin Cai, Dong Chen, Qiongchao Jiang, Lehang Lin, Zhen Chen, Jian‐You Liao, Yin Zhang, H. Phillip Koeffler, Dong Yin & Erwei Song. (2020) ATM‐Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions. Advanced Science 7:20, pages 2000157.
Crossref
Crossref
Radoslav Aleksandrov, Rossitsa Hristova, Stoyno Stoynov & Anastas Gospodinov. (2020) The Chromatin Response to Double-Strand DNA Breaks and Their Repair. Cells 9:8, pages 1853.
Crossref
Crossref
Cuige Zhu, Anna Rogers, Karama Asleh, Jennifer Won, Dongxia Gao, Samuel Leung, Shan Li, Kiran R. Vij, Jian Zhu, Jason M. Held, Zhongsheng You, Torsten O. Nielsen & Jieya Shao. (2020) Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer. Cell Reports 31:10, pages 107745.
Crossref
Crossref
Panagiotis Karakaidos, Dimitris Karagiannis & Theodoros Rampias. (2020) Resolving DNA Damage: Epigenetic Regulation of DNA Repair. Molecules 25:11, pages 2496.
Crossref
Crossref
Chiara Vittoria Colombo, Marco Gnugnoli, Elisa Gobbini & Maria Pia Longhese. (2020) How do cells sense DNA lesions?. Biochemical Society Transactions 48:2, pages 677-691.
Crossref
Crossref
Rhys M Williams, Luke A Yates & Xiaodong Zhang. (2020) Structures and regulations of ATM and ATR, master kinases in genome integrity. Current Opinion in Structural Biology 61, pages 98-105.
Crossref
Crossref
Kunming Zhao, Xingwen Wang, Xuting Xue, Li Li & Ying Hu. (2020) A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers. PLOS Biology 18:3, pages e3000666.
Crossref
Crossref
Diego Bonetti, Carlo Rinaldi, Jacopo Vertemara, Marco Notaro, Paolo Pizzul, Renata Tisi, Giuseppe Zampella & Maria Pia Longhese. (2020) DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends. Nucleic Acids Research 48:5, pages 2424-2441.
Crossref
Crossref
Yongsheng Li, Daniel J. McGrail, Natasha Latysheva, Song Yi, M. Madan Babu & Nidhi Sahni. (2020) Pathway perturbations in signaling networks: Linking genotype to phenotype. Seminars in Cell & Developmental Biology 99, pages 3-11.
Crossref
Crossref
Ji Eun Choi & Woo-Hyun Chung. (2019) Functional interplay between the oxidative stress response and DNA damage checkpoint signaling for genome maintenance in aerobic organisms. Journal of Microbiology 58:2, pages 81-91.
Crossref
Crossref
Apostolos Klinakis, Dimitris Karagiannis & Theodoros Rampias. (2019) Targeting DNA repair in cancer: current state and novel approaches. Cellular and Molecular Life Sciences 77:4, pages 677-703.
Crossref
Crossref
Mila Maidarti, Richard A. Anderson & Evelyn E. Telfer. (2020) Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing. Cells 9:1, pages 200.
Crossref
Crossref
Varsha Wagh, Pranav Joshi, Heena Jariyal & Neelam Chauhan. (2020) ATM and ATR checkpoint kinase pathways: A concise review. Advances in Human Biology 10:2, pages 51.
Crossref
Crossref
Marijke Jansma, Christian Linke-Winnebeck, Sebastian Eustermann, Katja Lammens, Dirk Kostrewa, Kristina Stakyte, Claudia Litz, Brigitte Kessler & Karl-Peter Hopfner. (2020) Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure 28:1, pages 83-95.e5.
Crossref
Crossref
Luke A. Yates, Rhys M. Williams, Sarem Hailemariam, Rafael Ayala, Peter Burgers & Xiaodong Zhang. (2020) Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure 28:1, pages 96-104.e3.
Crossref
Crossref
Renata Tisi, Jacopo Vertemara, Giuseppe Zampella & Maria Pia Longhese. (2020) Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks. Computational and Structural Biotechnology Journal 18, pages 1137-1152.
Crossref
Crossref
Jérôme Archambeau, Alice Blondel & Rémy Pedeux. (2019) Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation. Cancers 12:1, pages 58.
Crossref
Crossref
Sophie Cowman, Yuen Ngan Fan, Barry Pizer & Violaine Sée. (2019) Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells. BMC Cancer 19:1.
Crossref
Crossref
Sarem Hailemariam, Paolo De Bona, Roberto Galletto, Marcel Hohl, John H. Petrini & Peter M. Burgers. (2019) The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1ATM kinase. Journal of Biological Chemistry 294:49, pages 18846-18852.
Crossref
Crossref
Samantha A. Armstrong, Christopher W. Schultz, Ariana Azimi-Sadjadi, Jonathan R. Brody & Michael J. Pishvaian. (2019) ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications. Molecular Cancer Therapeutics 18:11, pages 1899-1908.
Crossref
Crossref
Audrey Mouche, Jérôme Archambeau, Charles Ricordel, Laura Chaillot, Nicolas Bigot, Thierry Guillaudeux, Muriel Grenon & Rémy Pedeux. (2019) ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks. Cell Death & Differentiation 26:11, pages 2344-2357.
Crossref
Crossref
Luca Menin, Chiara Vittoria Colombo, Giorgia Maestrini, Maria Pia Longhese & Michela Clerici. (2019) Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. Genetics 213:2, pages 411-429.
Crossref
Crossref
Zhi FangZezheng Pan. (2019) Essential Role of Ubiquitin-Fold Modifier 1 Conjugation in DNA Damage Response. DNA and Cell Biology 38:10, pages 1030-1039.
Crossref
Crossref
Alice Fiévet, Dorine Bellanger, Stéphanie Valence, Lenha Mobuchon, Alexandra Afenjar, Fabienne Giuliano, Catherine Dubois d'Enghien, Béatrice Parfait, Jean‐Michel Pedespan, Nathalie Auger, Guillaume Rieunier, Agnès Collet, Lydie Burglen, Dominique Stoppa‐Lyonnet & Marc‐Henri Stern. (2019) Three new cases of ataxia‐telangiectasia‐like disorder: No impairment of the ATM pathway, but S‐phase checkpoint defect. Human Mutation 40:10, pages 1690-1699.
Crossref
Crossref
Jiyu Xin, Zhu Xu, Xuejuan Wang, Yanhua Tian, Zhihui Zhang & Gang Cai. (2019) Structural basis of allosteric regulation of Tel1/ATM kinase. Cell Research 29:8, pages 655-665.
Crossref
Crossref
Erika Casari, Carlo Rinaldi, Antonio Marsella, Marco Gnugnoli, Chiara Vittoria Colombo, Diego Bonetti & Maria Pia Longhese. (2019) Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context. Frontiers in Molecular Biosciences 6.
Crossref
Crossref
Sarem Hailemariam, Sandeep Kumar & Peter M. Burgers. (2019) Activation of Tel1ATM kinase requires Rad50 ATPase and long nucleosome-free DNA but no DNA ends. Journal of Biological Chemistry 294:26, pages 10120-10130.
Crossref
Crossref
Corinne Cassani, Jacopo Vertemara, Matteo Bassani, Antonio Marsella, Renata Tisi, Giuseppe Zampella & Maria Pia Longhese. (2019) The ATP-bound conformation of the Mre11–Rad50 complex is essential for Tel1/ATM activation. Nucleic Acids Research 47:7, pages 3550-3567.
Crossref
Crossref
Geun-Hyoung Ha, Jae-Hoon Ji, Sunyoung Chae, Jihyun Park, Suhyeon Kim, Jin-Kwan Lee, Yonghyeon Kim, Sunwoo Min, Jeong-Min Park, Tae-Hong Kang, Ho Lee, Hyeseong Cho & Chang-Woo Lee. (2019) Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks. Nature Communications 10:1.
Crossref
Crossref
Roopesh Anand, Arti Jasrotia, Diana Bundschuh, Sean Michael Howard, Lepakshi Ranjha, Manuel Stucki & Petr Cejka. (2019) NBS1 promotes the endonuclease activity of the MRE11‐RAD50 complex by sensing CtIP phosphorylation. The EMBO Journal 38:7.
Crossref
Crossref
Bo Qin, Jia Yu, Somaira Nowsheen, Minghui Wang, Xinyi Tu, Tongzheng Liu, Honglin Li, Liewei Wang & Zhenkun Lou. (2019) UFL1 promotes histone H4 ufmylation and ATM activation. Nature Communications 10:1.
Crossref
Crossref
Chiara Vittoria Colombo, Luca Menin, Riccardo Ranieri, Diego Bonetti, Michela Clerici & Maria Pia Longhese. (2019) Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signaling Activities. Genetics 211:2, pages 515-530.
Crossref
Crossref
Dipendra Gautam, Gabrielle Stanley, Mary Owen & Eileen Bridge. (2019) Localization of the kinase Ataxia Telangiectasia Mutated to Adenovirus E4 mutant DNA replication centers is important for its inhibitory effect on viral DNA accumulation. Virology 527, pages 47-56.
Crossref
Crossref
Anastas Gospodinov & Iva Ugrinova. 2019. DNA Repair. DNA Repair
69
94
.
Sonia Jimeno, Fernando Mejías-Navarro, Rosario Prados-Carvajal & Pablo Huertas. 2019. DNA Repair. DNA Repair
95
134
.
Julyun Oh & Lorraine Symington. (2018) Role of the Mre11 Complex in Preserving Genome Integrity. Genes 9:12, pages 589.
Crossref
Crossref
Ireneusz Litwin, Ewa Pilarczyk & Robert Wysocki. (2018) The Emerging Role of Cohesin in the DNA Damage Response. Genes 9:12, pages 581.
Crossref
Crossref
Julyun Oh, So Jung Lee, Rodney Rothstein & Lorraine S. Symington. (2018) Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability. Cell Reports 25:7, pages 1681-1692.e4.
Crossref
Crossref
Raíssa Bernardes da Silva, Carlos Renato Machado, Aldo Rogelis Aquiles Rodrigues & André Luiz Pedrosa. (2018) Selective human inhibitors of ATR and ATM render Leishmania major promastigotes sensitive to oxidative damage. PLOS ONE 13:9, pages e0205033.
Crossref
Crossref
Diego Bonetti, Chiara Vittoria Colombo, Michela Clerici & Maria Pia Longhese. (2018) Processing of DNA Ends in the Maintenance of Genome Stability. Frontiers in Genetics 9.
Crossref
Crossref
Abantika Ganguly, Lan Guo, Lingling Sun, Fang Suo, Li-Lin Du & Paul Russell. (2018) Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks. PLOS Genetics 14:8, pages e1007595.
Crossref
Crossref
Elisa Gobbini, Corinne Cassani, Jacopo Vertemara, Weibin Wang, Fabiana Mambretti, Erika Casari, Patrick Sung, Renata Tisi, Giuseppe Zampella & Maria Pia Longhese. (2018)
The
MRX
complex regulates Exo1 resection activity by altering
DNA
end structure
. The EMBO Journal 37:16.
Crossref
Crossref
Zhiming Li, Yinglu Li, Ming Tang, Bin Peng, Xiaopeng Lu, Qiaoyan Yang, Qian Zhu, Tianyun Hou, Meiting Li, Chaohua Liu, Lina Wang, Xingzhi Xu, Ying Zhao, Haiying Wang, Yang Yang & Wei-Guo Zhu. (2018) Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair. Cell Research 28:7, pages 756-770.
Crossref
Crossref
Aleem SyedJohn A. Tainer. (2018) The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair. Annual Review of Biochemistry 87:1, pages 263-294.
Crossref
Crossref
Kim Kiat Lim, Thi Thuy Trang Nguyen, Adelicia Yongling Li, Yee Phan Yeo & Ee Sin Chen. (2018) Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast. Nucleic Acids Research 46:10, pages 5061-5074.
Crossref
Crossref
Oliver Limbo, Yoshiki Yamada & Paul Russell. (2018) Mre11-Rad50–dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1. Molecular Biology of the Cell 29:11, pages 1389-1399.
Crossref
Crossref
Chloe Girard, Baptiste Roelens, Karl A. Zawadzki & Anne M. Villeneuve. (2018)
Interdependent and separable functions of
Caenorhabditis elegans
MRN-C complex members couple formation and repair of meiotic DSBs
. Proceedings of the National Academy of Sciences 115:19.
Crossref
Crossref
Keun P. Kim & Ekaterina V. Mirkin. (2018) So similar yet so different: The two ends of a double strand break. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 809, pages 70-80.
Crossref
Crossref
Corinne Cassani, Elisa Gobbini, Jacopo Vertemara, Weibin Wang, Antonio Marsella, Patrick Sung, Renata Tisi, Giuseppe Zampella & Maria Pia Longhese. (2018) Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance. Nucleic Acids Research 46:6, pages 2990-3008.
Crossref
Crossref
Stefan Imseng, Christopher HS Aylett & Timm Maier. (2018) Architecture and activation of phosphatidylinositol 3-kinase related kinases. Current Opinion in Structural Biology 49, pages 177-189.
Crossref
Crossref
Kurt W. Runge & Yanhui Li. (2017) A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining. Current Genetics 64:2, pages 359-364.
Crossref
Crossref
Yongchao Zhao, Mingjia Tan, Xia Liu, Xiufang Xiong & Yi Sun. (2018) Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2–MRN–ATM axes. Cell Death & Disease 9:2.
Crossref
Crossref
Alice Bourgeois, Caroline Lambert, Karima Habbout, Benoit Ranchoux, Stéphanie Paquet-Marceau, Isabelle Trinh, Sandra Breuils-Bonnet, Renée Paradis, Valérie Nadeau, Roxane Paulin, Steeve Provencher, Sébastien Bonnet & Olivier Boucherat. (2017) FOXM1 promotes pulmonary artery smooth muscle cell expansion in pulmonary arterial hypertension. Journal of Molecular Medicine 96:2, pages 223-235.
Crossref
Crossref
Yifan Wang, Jayanthi Gudikote, Uma Giri, Jun Yan, Weiye Deng, Rui Ye, Wen Jiang, Nan Li, Brian P. Hobbs, Jing Wang, Stephen G. Swisher, Junya Fujimoto, Ignacio I. Wistuba, Ritsuko Komaki, John V. Heymach & Steven H. Lin. (2018) RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer. Clinical Cancer Research 24:2, pages 341-350.
Crossref
Crossref
Ji-Hoon Lee, Michael R. Mand, Chung-Hsuan KaoYi ZhouSeung W. Ryu, Alicia L. RichardsJoshua J. CoonTanya T. Paull. (2018) ATM directs DNA damage responses and proteostasis via genetically separable pathways. Science Signaling 11:512.
Crossref
Crossref
Davide Moiani, Daryl A. Ronato, Chris A. Brosey, Andrew S. Arvai, Aleem Syed, Jean-Yves Masson, Elena Petricci & John A. Tainer. 2018. Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair
205
241
.
Anika M. Weber & Anderson J. Ryan. 2018. Targeting the DNA Damage Response for Anti-Cancer Therapy. Targeting the DNA Damage Response for Anti-Cancer Therapy
155
183
.
Atsushi Shibata & Penny Jeggo. 2018. Targeting the DNA Damage Response for Anti-Cancer Therapy. Targeting the DNA Damage Response for Anti-Cancer Therapy
129
154
.
Naoaki Fujii. (2017) Potential Strategies to Target Protein–Protein Interactions in the DNA Damage Response and Repair Pathways. Journal of Medicinal Chemistry 60:24, pages 9932-9959.
Crossref
Crossref
Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi & C Zhou. (2017) Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics. Oncogene 36:50, pages 6839-6849.
Crossref
Crossref
Sharad C. Paudyal, Shan Li, Hong Yan, Tony Hunter & Zhongsheng You. (2017) Dna2 initiates resection at clean DNA double-strand breaks. Nucleic Acids Research 45:20, pages 11766-11781.
Crossref
Crossref
Kinjal Majumder, Igor Etingov & David Pintel. (2017) Protoparvovirus Interactions with the Cellular DNA Damage Response. Viruses 9:11, pages 323.
Crossref
Crossref
Rosa Pennisi, Antonio Antoccia, Stefano Leone, Paolo Ascenzi & Alessandra di Masi. (2017) Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks. The FEBS Journal 284:15, pages 2378-2395.
Crossref
Crossref
Wouter S. Hoogenboom, Daisy Klein Douwel & Puck Knipscheer. (2017) Xenopus egg extract: A powerful tool to study genome maintenance mechanisms. Developmental Biology 428:2, pages 300-309.
Crossref
Crossref
Domagoj Baretić, Hannah K. PollardDavid I. FisherChristopher M. JohnsonBalaji SanthanamCaroline M. TrumanTomas KoubaAlan R. FershtChristopher PhillipsRoger L. Williams. (2017) Structures of closed and open conformations of dimeric human ATM. Science Advances 3:5.
Crossref
Crossref
Mrinalini Tiwari, Suhel Parvez & Paban K. Agrawala. (2021) Role of some epigenetic factors in DNA damage response pathway. AIMS Genetics 04:01, pages 069-083.
Crossref
Crossref
Yanhui Li, Jinyu Wang, Gang Zhou, Michael Lajeunesse, Nga Le, Brittany N Stawicki, Yalitza Lopez Corcino, Kathleen L Berkner & Kurt W Runge. (2017)
Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in
Schizosaccharomyces pombe
. Genetics 206:1, pages 481-496.
Crossref
Crossref
Kasper Røjkjær Andersen. (2017) Insights into Rad3 kinase recruitment from the crystal structure of the DNA damage checkpoint protein Rad26. Journal of Biological Chemistry 292:20, pages 8149-8157.
Crossref
Crossref
Jun Hyun Kim, Malgorzata Grosbart, Roopesh Anand, Claire Wyman, Petr Cejka & John H.J. Petrini. (2017) The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression. Cell Reports 18:2, pages 496-507.
Crossref
Crossref
Haoyue Zhang, Linlin Sun, Kun Wang, Di Wu, Mason Trappio, Celeste Witting & Kan Cao. (2016) Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLOS ONE 11:12, pages e0167454.
Crossref
Crossref
Julyun Oh, Amr Al-Zain, Elda Cannavo, Petr Cejka & Lorraine S. Symington. (2016) Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex. Molecular Cell 64:2, pages 405-415.
Crossref
Crossref
Matteo Villa, Corinne Cassani, Elisa Gobbini, Diego Bonetti & Maria Pia Longhese. (2016) Coupling end resection with the checkpoint response at DNA double-strand breaks. Cellular and Molecular Life Sciences 73:19, pages 3655-3663.
Crossref
Crossref
Sumit Kumar, Rajnish Kumar Singh & Ramovatar Meena. (2016) Emerging targets for radioprotection and radiosensitization in radiotherapy. Tumor Biology 37:9, pages 11589-11609.
Crossref
Crossref
Marek Adamowicz, Jelena Vermezovic & Fabrizio d’Adda di Fagagna. (2016) NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex. Cell Reports 16:8, pages 2068-2076.
Crossref
Crossref
Xuejuan Wang, Huanyu Chu, Mengjuan Lv, Zhihui Zhang, Shuwan Qiu, Haiyan Liu, Xuetong Shen, Weiwu Wang & Gang Cai. (2016) Structure of the intact ATM/Tel1 kinase. Nature Communications 7:1.
Crossref
Crossref
Ignacio M. Fenoy, Silvina S. Bogado, Susana M. Contreras, Vanesa Gottifredi & Sergio O. Angel. (2016) The Knowns Unknowns: Exploring the Homologous Recombination Repair Pathway in Toxoplasma gondii. Frontiers in Microbiology 7.
Crossref
Crossref
Florian Ulrich Seifert, Katja Lammens, Gabriele Stoehr, Brigitte Kessler & Karl‐Peter Hopfner. (2016)
Structural mechanism of
ATP
‐dependent
DNA
binding and
DNA
end bridging by eukaryotic Rad50
. The EMBO Journal 35:7, pages 759-772.
Crossref
Crossref
Yu-Jie Chen, Yu-Chien Chuang, Chi-Ning Chuang, Yun-Hsin Cheng, Chuang-Rung Chang, Chih-Hsiang Leng & Ting-Fang Wang. (2016)
S. cerevisiae
Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex
. Nucleic Acids Research 44:5, pages 2199-2213.
Crossref
Crossref
Ayushi Guleria & Sudhir Chandna. (2016) ATM kinase: Much more than a DNA damage responsive protein. DNA Repair 39, pages 1-20.
Crossref
Crossref
Corinne Cassani, Elisa Gobbini, Weibin Wang, Hengyao Niu, Michela Clerici, Patrick Sung & Maria Pia Longhese. (2016) Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks. PLOS Biology 14:2, pages e1002387.
Crossref
Crossref
Shaliny Ramachandran & Alberto Martin. 2016. Encyclopedia of Immunobiology. Encyclopedia of Immunobiology
134
143
.
Wei FengScott D. Michaels. (2015) Accessing the Inaccessible: The Organization, Transcription, Replication, and Repair of Heterochromatin in Plants. Annual Review of Genetics 49:1, pages 439-459.
Crossref
Crossref
Andrew Campbell, Brittany Krupp, Jared Bushman, Mark Noble, Christoph Pröschel & Margot Mayer-Pröschel. (2015) A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden. Human Molecular Genetics 24:22, pages 6331-6349.
Crossref
Crossref
Martin Lavin, Sergei Kozlov, Magtouf Gatei & Amanda Kijas. (2015) ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor. Biomolecules 5:4, pages 2877-2902.
Crossref
Crossref
Hiroo Ogi, Greicy H. Goto, Avik Ghosh, Sevil Zencir, Everett Henry & Katsunori Sugimoto. (2015) Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition. Molecular Biology of the Cell 26:19, pages 3480-3488.
Crossref
Crossref
Panfei Wang, Changmin Peng, Xia Liu, Hailong Liu, Yali Chen, Li Zheng, Baolin Han & Huadong Pei. (2015) OGT Mediated Histone H2B S112 GlcNAcylation Regulates DNA Damage Response. Journal of Genetics and Genomics 42:9, pages 467-475.
Crossref
Crossref
Tanya T. Paull. (2015) Mechanisms of ATM Activation. Annual Review of Biochemistry 84:1, pages 711-738.
Crossref
Crossref
Saeko Takada, Eric R. Collins & Kayo Kurahashi. (2015)
The FHA domain determines
Drosophila
Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses
. Molecular Biology of the Cell 26:10, pages 1811-1828.
Crossref
Crossref
Sugith Babu Badugu, Shaik Abdul Nabi, Pratap Vaidyam, Shyamasree Laskar, Sunanda Bhattacharyya & Mrinal Kanti Bhattacharyya. (2015) Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function. PLOS ONE 10:5, pages e0125358.
Crossref
Crossref
Anika Maria Weber & Anderson Joseph Ryan. (2015) ATM and ATR as therapeutic targets in cancer. Pharmacology & Therapeutics 149, pages 124-138.
Crossref
Crossref
Xingya Xu, Norihiko Nakazawa & Mitsuhiro Yanagida. (2015) Condensin HEAT Subunits Required for DNA Repair, Kinetochore/Centromere Function and Ploidy Maintenance in Fission Yeast. PLOS ONE 10:3, pages e0119347.
Crossref
Crossref
Julien Lafrance-Vanasse, Gareth J. Williams & John A. Tainer. (2015) Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair. Progress in Biophysics and Molecular Biology 117:2-3, pages 182-193.
Crossref
Crossref
Kelly GraySheetal KumarNichola FiggJames HarrisonLauren BakerJohn MercerTrevor LittlewoodMartin Bennett. (2015) Effects of DNA Damage in Smooth Muscle Cells in Atherosclerosis. Circulation Research 116:5, pages 816-826.
Crossref
Crossref
Sara N Andres, C Denise Appel, James W Westmoreland, Jessica S Williams, Yvonne Nguyen, Patrick D Robertson, Michael A Resnick & R Scott Williams. (2015) Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair. Nature Structural & Molecular Biology 22:2, pages 158-166.
Crossref
Crossref
Sujin Park, Jin Muk Kang, Staci Jakyong Kim, Hyojung Kim, Suntaek Hong, Young Jae Lee & Seong-Jin Kim. (2014) Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair. Cellular and Molecular Life Sciences 72:3, pages 583-596.
Crossref
Crossref
Poorwa Awasthi, Marco Foiani & Amit Kumar. (2015) ATM and ATR signaling at a glance. Journal of Cell Science.
Crossref
Crossref
Domenica Cilli, Cristiana Mirasole, Rosa Pennisi, Valeria Pallotta, Angelo D'Alessandro, Antonio Antoccia, Lello Zolla, Paolo Ascenzi & Alessandra di Masi. (2014) Identification of the Interactors of Human Nibrin (NBN) and of Its 26 kDa and 70 kDa Fragments Arising from the NBN 657del5 Founder Mutation. PLoS ONE 9:12, pages e114651.
Crossref
Crossref
Domagoj Baretić & Roger L. Williams. (2014) PIKKs — the solenoid nest where partners and kinases meet. Current Opinion in Structural Biology 29, pages 134-142.
Crossref
Crossref
Karl-Peter Hopfner. (2014) ATP puts the brake on DNA double-strand break repair. BioEssays 36:12, pages 1170-1178.
Crossref
Crossref
Katrin Rein & Travis H. Stracker. (2014) The MRE11 complex: An important source of stress relief. Experimental Cell Research 329:1, pages 162-169.
Crossref
Crossref
Fengxia Du, Minjie Zhang, Xiaohua Li, Caiyun Yang, Hao Meng, Dong Wang, Shuang Chang, Ye Xu, Brendan Price & Yingli Sun. (2014) Dimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair. Biochemical and Biophysical Research Communications 452:4, pages 1034-1039.
Crossref
Crossref
Daniel C. Anacker, Dipendra Gautam, Kenric A. Gillespie, William H. Chappell & Cary A. Moody. (2014) Productive Replication of Human Papillomavirus 31 Requires DNA Repair Factor Nbs1. Journal of Virology 88:15, pages 8528-8544.
Crossref
Crossref
Yuki Yamamoto, Mamiko Miyamoto, Daisuke Tatsuda, Michiaki Kubo, Hitoshi Nakagama, Yusuke Nakamura, Hitoshi Satoh, Koichi Matsuda, Toshiki Watanabe & Tsutomu Ohta. (2014)
A Rare Polymorphic Variant of
NBS1
Reduces DNA Repair Activity and Elevates Chromosomal Instability
. Cancer Research 74:14, pages 3707-3715.
Crossref
Crossref
Francesca Damiola, Maroulio Pertesi, Javier Oliver, Florence Le Calvez-Kelm, Catherine Voegele, Erin L Young, Nivonirina Robinot, Nathalie Forey, Geoffroy Durand, Maxime P Vallée, Kayoko Tao, Terrell C Roane, Gareth J Williams, John L Hopper, Melissa C Southey, Irene L Andrulis, Esther M John, David E Goldgar, Fabienne Lesueur & Sean V Tavtigian. (2014) Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. Breast Cancer Research 16:3.
Crossref
Crossref
B. Liu, X. Chen, Z.Q. Wang & W.M. Tong. (2013)
DNA damage and oxidative injury are associated with hypomyelination in the corpus callosum of newborn Nbn
CNS‐del
mice
. Journal of Neuroscience Research 92:2, pages 254-266.
Crossref
Crossref
Shun Matsuda, Ryo Matsuda, Yoko Matsuda, Shin-ya Yanagisawa, Masae Ikura, Tsuyoshi Ikura & Tomonari Matsuda. (2014) An Easy-to-use Genotoxicity Assay Using EGFP-MDC1-expressing Human Cells. Genes and Environment 36:1, pages 17-28.
Crossref
Crossref
Enea Gino Di Domenico, Elena Romano, Paola Del Porto & Fiorentina Ascenzioni. (2014) Multifunctional Role of ATM/Tel1 Kinase in Genome Stability: From the DNA Damage Response to Telomere Maintenance. BioMed Research International 2014, pages 1-17.
Crossref
Crossref
Yosef Shiloh. 2015. Molecular Oncology. Molecular Oncology
403
422
.
Megan McKerlie, John R. Walker, Taylor R. H. Mitchell, Florence R. Wilson & Xu-Dong Zhu. (2013) Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation. Nucleic Acids Research 41:22, pages 10268-10282.
Crossref
Crossref
Michela Clerici, Camilla Trovesi, Alessandro Galbiati, Giovanna Lucchini & Maria Pia Longhese. (2013) Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends. The EMBO Journal, pages n/a-n/a.
Crossref
Crossref
Xiaoqing Chen, Sharad C. Paudyal, Re-I Chin & Zhongsheng You. (2013) PCNA promotes processive DNA end resection by Exo1. Nucleic Acids Research 41:20, pages 9325-9338.
Crossref
Crossref
Elisa Gobbini, Daniele Cesena, Alessandro Galbiati, Arianna Lockhart & Maria Pia Longhese. (2013) Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks. DNA Repair 12:10, pages 791-799.
Crossref
Crossref
Anastas Gospodinov & Zdenko Herceg. (2013) Chromatin structure in double strand break repair. DNA Repair 12:10, pages 800-810.
Crossref
Crossref
Dipendra Gautam & Eileen Bridge. (2013) The Kinase Activity of Ataxia-Telangiectasia Mutated Interferes with Adenovirus E4 Mutant DNA Replication. Journal of Virology 87:15, pages 8687-8696.
Crossref
Crossref
Joon Lee & William G. Dunphy. (2013) The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. Molecular Biology of the Cell 24:9, pages 1343-1353.
Crossref
Crossref
Na Li, Yanzhe Xu, Jian Zheng, Lan Jiang, Yonghe You, Hongchun Wu, Wei Li, Depei Wu & Yifeng Zhou. (2013) NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myeloid leukemia in a Chinese population. Molecular Biology Reports 40:5, pages 3749-3756.
Crossref
Crossref
Yu-Chen Hu, Bau-Shan Hsieh, Hsiao-Ling Cheng, Li-Wen Huang, Tzu-Ching Huang, I-Yu Huang & Kee-Lung Chang. (2013) Osteoblasts survive the arsenic trioxide treatment by activation of ATM-mediated pathway. Biochemical Pharmacology 85:7, pages 1018-1026.
Crossref
Crossref
Frank Tobias, Daniel Löb, Nicor Lengert, Marco Durante, Barbara Drossel, Gisela Taucher-Scholz & Burkhard Jakob. (2013) Spatiotemporal Dynamics of Early DNA Damage Response Proteins on Complex DNA Lesions. PLoS ONE 8:2, pages e57953.
Crossref
Crossref
Takeshi KondoJunya KobayashiTatsuya SaitohKenta MaruyamaKen J. Ishii, Glen N. Barber, Kenshi KomatsuShizuo AkiraTaro Kawai. (2013) DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking. Proceedings of the National Academy of Sciences 110:8, pages 2969-2974.
Crossref
Crossref
Anastas Gospodinov & Zdenko Herceg. (2013) Shaping chromatin for repair. Mutation Research/Reviews in Mutation Research 752:1, pages 45-60.
Crossref
Crossref
Clara Correia Reis, Sílvia Batista & Miguel Godinho Ferreira. (2012) The fission yeast MRN complex tethers dysfunctional telomeres for NHEJ repair. The EMBO Journal 31:24, pages 4576-4586.
Crossref
Crossref
Oliver Limbo, Davide Moiani, Aryandi Kertokalio, Claire Wyman, John A. Tainer & Paul Russell. (2012) Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Research 40:22, pages 11435-11449.
Crossref
Crossref
Veronica Baldo, Jason Liang, Guoliang Wang & Huilin Zhou. (2012) Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance. Biomolecules 2:4, pages 505-523.
Crossref
Crossref
Larry H. Thompson. (2012) Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography. Mutation Research/Reviews in Mutation Research 751:2, pages 158-246.
Crossref
Crossref
Gunjan D. Mehta, Syed Meraj Azhar Rizvi & Santanu Kumar Ghosh. (2012) Cohesin: A guardian of genome integrity. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:8, pages 1324-1342.
Crossref
Crossref
Steven S. FosterSaurav DeLinda K. Johnson, John H. J. PetriniTravis H. Stracker. (2012) Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression. Proceedings of the National Academy of Sciences 109:25, pages 9953-9958.
Crossref
Crossref
Juan Wu, Xian Zhang, Ling Zhang, Ching-Yuan Wu, Abdol Hossein Rezaeian, Chia-Hsin Chan, Ju-Mei Li, Jing Wang, Yuan Gao, Fei Han, Yun Seong Jeong, Xiandao Yuan, Kum Kum Khanna, Jianping Jin, Yi-Xin Zeng & Hui-Kuan Lin. (2012) Skp2 E3 Ligase Integrates ATM Activation and Homologous Recombination Repair by Ubiquitinating NBS1. Molecular Cell 46:3, pages 351-361.
Crossref
Crossref
Karen Finn, Noel Francis Lowndes & Muriel Grenon. (2011) Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Cellular and Molecular Life Sciences 69:9, pages 1447-1473.
Crossref
Crossref
A. Cerbinskaite, A. Mukhopadhyay, E.R. Plummer, N.J. Curtin & R.J. Edmondson. (2012) Defective homologous recombination in human cancers. Cancer Treatment Reviews 38:2, pages 89-100.
Crossref
Crossref
Yan Yan Hou, Meng Tiak Toh & Xueying Wang. (2012) NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity. Cell Biochemistry and Function 30:3, pages 233-242.
Crossref
Crossref
Kenzo Fukunaga, Yukinori Hirano & Katsunori Sugimoto. (2012) Subtelomere-binding protein Tbf1 and telomere-binding protein Rap1 collaborate to inhibit localization of the Mre11 complex to DNA ends in budding yeast. Molecular Biology of the Cell 23:2, pages 347-359.
Crossref
Crossref
Rebecca Vogel, Michael Seyffert, Regina Strasser, Anna P. de Oliveira, Christiane Dresch, Daniel L. Glauser, Nelly Jolinon, Anna Salvetti, Matthew D. Weitzman, Mathias Ackermann & Cornel Fraefel. (2012) Adeno-Associated Virus Type 2 Modulates the Host DNA Damage Response Induced by Herpes Simplex Virus 1 during Coinfection. Journal of Virology 86:1, pages 143-155.
Crossref
Crossref
Carolin Möckel, Katja Lammens, Alexandra Schele & Karl-Peter Hopfner. (2012) ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex. Nucleic Acids Research 40:2, pages 914-927.
Crossref
Crossref
Jeffrey J. Bednarski & Barry P. Sleckman. 2012. Advances in Immunology Volume 116. Advances in Immunology Volume 116
175
204
.
Ye Xu, Chang Xu & Brendan D. Price. 2012. Mechanisms of DNA Repair. Mechanisms of DNA Repair
263
288
.
Petra Langerak & Paul Russell. (2011) Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair. Philosophical Transactions of the Royal Society B: Biological Sciences 366:1584, pages 3562-3571.
Crossref
Crossref
Young Bong Park, Jina Chae, Young Chang Kim & Yunje Cho. (2011) Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations. Structure 19:11, pages 1591-1602.
Crossref
Crossref
Fulvio Ricceri, Paola Porcedda, Alessandra Allione, Valentina Turinetto, Silvia Polidoro, Simonetta Guarrera, Fabio Rosa, Floriana Voglino, Annamaria Pezzotti, Valentina Minieri, Lisa Accomasso, Elisa Cibrario Rocchietti, Luca Orlando, Claudia Giachino & Giuseppe Matullo. (2011) Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: A genotype–phenotype correlation study. DNA Repair 10:10, pages 1044-1050.
Crossref
Crossref
Shahzad Bhatti, Sergei Kozlov, Ammad Ahmad Farooqi, Ali Naqi, Martin Lavin & Kum Kum Khanna. (2011) ATM protein kinase: the linchpin of cellular defenses to stress. Cellular and Molecular Life Sciences 68:18, pages 2977-3006.
Crossref
Crossref
Yasuyoshi Oka, Keiji Suzuki, Motohiro Yamauchi, Norisato Mitsutake & Shunichi Yamashita. (2011) Recruitment of the cohesin loading factor NIPBL to DNA double-strand breaks depends on MDC1, RNF168 and HP1γ in human cells. Biochemical and Biophysical Research Communications 411:4, pages 762-767.
Crossref
Crossref
Caroline E. Lilley, Mira S. Chaurushiya, Chris Boutell, Roger D. Everett & Matthew D. Weitzman. (2011) The Intrinsic Antiviral Defense to Incoming HSV-1 Genomes Includes Specific DNA Repair Proteins and Is Counteracted by the Viral Protein ICP0. PLoS Pathogens 7:6, pages e1002084.
Crossref
Crossref
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