Advanced search
Publication Cover
Molecular and Cellular Biology Volume 25, 2005 - Issue 13
Submit an article Journal homepage
96
Views
86
CrossRef citations to date
0
Altmetric
Mammalian Genetic Models with Minimal or Complex Phenotypes

Generation and Characterization of Rac3 Knockout Mice

Sara Corbetta1 Department of Molecular Biology and Functional Genomics
,
Sara Gualdoni1 Department of Molecular Biology and Functional Genomics
,
Chiara Albertinazzi1 Department of Molecular Biology and Functional Genomics
,
Simona Paris1 Department of Molecular Biology and Functional Genomics
,
Laura Croci2 Department of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
,
G. Giacomo Consalez2 Department of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
&
Ivan de Curtis1 Department of Molecular Biology and Functional GenomicsCorrespondence[email protected]
 show all
Pages 5763-5776 | Received 19 Nov 2004, Accepted 17 Mar 2005, Published online: 27 Mar 2023

Citations (86)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Francisco Llavero, Alazne Arrazola Sastre, Miriam Luque Montoro, Miguel A. Martín, Joaquín Arenas, Alejandro Lucia & José L. Zugaza. (2021) Small GTPases of the Ras superfamily and glycogen phosphorylase regulation in T cells. Small GTPases 12:2, pages 106-113.
Read now
Carlo C Campa, Elisa Ciraolo, Alessandra Ghigo, Giulia Germena & Emilio Hirsch. (2015) Crossroads of PI3K and Rac pathways. Small GTPases 6:2, pages 71-80.
Read now
Xiwu Chen, Tristin D. Abair, Maria R. Ibanez, Yan Su, Mark R. Frey, Rebecca S. Dise, D. Brent Polk, Amar B. Singh, Raymond C. Harris, Roy Zent & Ambra Pozzi. (2007) Integrin α1β1 Controls Reactive Oxygen Species Synthesis by Negatively Regulating Epidermal Growth Factor Receptor-Mediated Rac Activation. Molecular and Cellular Biology 27:9, pages 3313-3326.
Read now

Articles from other publishers (83)

Takashi Nakamura, Hirofumi Sakaguchi, Hiroaki Mohri, Yuzuru Ninoyu, Akihiro Goto, Taro Yamaguchi, Yoshitaka Hishikawa, Michiyuki Matsuda, Naoaki Saito & Takehiko Ueyama. (2023) Dispensable role of Rac1 and Rac3 after cochlear hair cell specification. Journal of Molecular Medicine.
Crossref
Kei-ichi Katayama, Yi Zheng & Norimitsu Inoue. (2023) Rac is required for the survival of cortical neurons. Experimental Neurology 361, pages 114316.
Crossref
Ke-Cheng Zhu, Jun Liu, Bao-Suo Liu, Hua-Yang Guo, Nan Zhang, Liang Guo, Shi-Gui Jiang & Dian-Chang Zhang. (2022) Functional characterization of four ToRac genes and their association with anti-parasite traits in Trachinotus ovatus (Linnaeus, 1758). Aquaculture 560, pages 738514.
Crossref
Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Gabrielle Brown, Manish J Butte, Esteban C Dell'Angelica, Naghmeh Dorrani, Emilie D Douine, Brent L Fogel, Irma Gutierrez, Alden Huang, Deborah Krakow, Hane Lee, Sandra K Loo, Bryan C Mak, Martin G Martin, Julian A Martínez-Agosto, Elisabeth McGee, Stanley F Nelson, Shirley Nieves-Rodriguez, Christina G S Palmer, Jeanette C Papp, Neil H Parker, Genecee Renteria, Janet S Sinsheimer, Jijun Wan, Lee-kai Wang, Katherine Wesseling Perry, Vincenzo Nigro, Nicola Brunetti-Pierri, Giorgio Casari, Gerarda Cappuccio, Annalaura Torella, Michele Pinelli, Francesco Musacchia, Margherita Mutarelli, Diego Carrella, Giuseppina Vitiello, Valeria Capra, Giancarlo Parenti, Vincenzo Leuzzi, Angelo Selicorni, Silvia Maitz, Sandro Banfi, Marcella Zollino, Mario Montomoli, Donatelli Milani, Corrado Romano, Albina Tummolo, Daniele De Brasi, Antonietta Coppola, Claudia Santoro, Angela Peron, Chiara Pantaleoni, Raffaele Castello, Stefano D’Arrigo, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain & Koh ichi Nagata. (2022) Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes. Brain 145:9, pages 3308-3327.
Crossref
Kei-ichi Katayama, Yi Zheng & Norimitsu Inoue. (2022) Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer. Scientific Reports 12:1.
Crossref
Carla Guenther. (2022) β2-Integrins – Regulatory and Executive Bridges in the Signaling Network Controlling Leukocyte Trafficking and Migration. Frontiers in Immunology 13.
Crossref
Marcello Scala, Masashi Nishikawa, Koh-ichi Nagata & Pasquale Striano. (2021) Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies. Cells 10:12, pages 3395.
Crossref
Elizabeth Hampson, Elpida Tsonou, Martin J. Baker, David C. Hornigold, Roderick E. Hubbard, Andrew Massey & Heidi C. E. Welch. (2021) P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells. Cells 10:9, pages 2474.
Crossref
Marta Pellegatta, Caterina Berti, Edward Hurley, Marilena Palmisano, Ivan de Curtis, M. Laura Feltri & Luciana R. Frick. (2021) Rac1 and Rac3 have opposite functions in Schwann cells during developmental myelination. Neuroscience Letters 753, pages 135868.
Crossref
Silvio Paone, Sarah D’Alessandro, Silvia Parapini, Francesco Celani, Valentina Tirelli, Manoochehr Pourshaban & Anna Olivieri. (2020) Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion. Scientific Reports 10:1.
Crossref
Hannah Benisty, Marc Weber, Xavier Hernandez-Alias, Martin H. Schaefer & Luis Serrano. (2020) Mutation bias within oncogene families is related to proliferation-specific codon usage. Proceedings of the National Academy of Sciences 117:48, pages 30848-30856.
Crossref
Xiaohui Wang, Dongbin Liu, Fangzhen Wei, Yue Li, Xuefeng Wang, Linjie Li, Guan Wang, Shuli Zhang & Lei Zhang. (2020) Stress-Sensitive Protein Rac1 and Its Involvement in Neurodevelopmental Disorders. Neural Plasticity 2020, pages 1-11.
Crossref
Daji Guo, Xiaoman Yang & Lei Shi. (2020) Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics. Cells 9:4, pages 835.
Crossref
Takehiko Ueyama, Megumi Sakuma, Mio Nakatsuji, Tatsuya Uebi, Takeshi Hamada, Atsu Aiba & Naoaki Saito. (2020) Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes. Journal of Investigative Dermatology 140:1, pages 75-84.e6.
Crossref
Melanie Laurin, Nicholas C Gomez, John Levorse, Ataman Sendoel, Megan Sribour & Elaine Fuchs. (2019) An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. eLife 8.
Crossref
Ivan de Curtis. (2019) The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer. Cells 8:9, pages 1063.
Crossref
Roberta Pennucci, Irene Gucciardi & Ivan de Curtis. (2019) Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons. PLOS ONE 14:8, pages e0220496.
Crossref
Hidenori Ito, Rika Morishita, Makoto Mizuno, Hidenori Tabata & Koh-ichi Nagata. (2019) Rho family GTPases, Rac and Cdc42, control the localization of neonatal dentate granule cells during brain development. Hippocampus 29:7, pages 569-578.
Crossref
Theodora Kalpachidou, Lisa Spiecker, Michaela Kress & Serena Quarta. (2019) Rho GTPases in the Physiology and Pathophysiology of Peripheral Sensory Neurons. Cells 8:6, pages 591.
Crossref
Haley Rose Barlow & Ondine Cleaver. (2019) Building Blood Vessels—One Rho GTPase at a Time. Cells 8:6, pages 545.
Crossref
Tom Kunschmann, Stefanie Puder, Tony Fischer, Anika Steffen, Klemens Rottner & Claudia Tanja Mierke. (2019) The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices. Scientific Reports 9:1.
Crossref
Valerie Durand-Onaylı, Theresa Haslauer, Andrea Härzschel & Tanja Hartmann. (2018) Rac GTPases in Hematological Malignancies. International Journal of Molecular Sciences 19:12, pages 4041.
Crossref
Valentina Zamboni, Rebecca Jones, Alessandro Umbach, Alessandra Ammoni, Maria Passafaro, Emilio Hirsch & Giorgio Merlo. (2018) Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities. International Journal of Molecular Sciences 19:6, pages 1821.
Crossref
Sira A. Franchi, Romina Macco, Veronica Astro, Diletta Tonoli, Elisa Savino, Flavia Valtorta, Kristyna Sala, Martina Botta & Ivan de Curtis. (2018) A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence. Frontiers in Cellular Neuroscience 11.
Crossref
Daniel Brandwein & Zhixiang Wang. (2017) Interaction between Rho GTPases and 14-3-3 Proteins. International Journal of Molecular Sciences 18:10, pages 2148.
Crossref
Dai Suzuki, Jason R Bush, Dawn-Marie Bryce, Ryutaro Kamijo & Frank Beier. (2017) Rac1 Dosage Is Crucial for Normal Endochondral Bone Growth. Endocrinology 158:10, pages 3386-3398.
Crossref
Takashi Nakamura, Takehiko Ueyama, Yuzuru Ninoyu, Hirofumi Sakaguchi, Narantsog Choijookhuu, Yoshitaka Hishikawa, Hiroshi Kiyonari, Masaaki Kohta, Mizuho Sakahara, Ivan de Curtis, Eiji Kohmura, Yasuo Hisa, Atsu Aiba & Naoaki Saito. (2017) Novel role of Rac-Mid1 signaling in medial cerebellar development. Development 144:10, pages 1863-1875.
Crossref
Yun-Ju Lai, Jui-Cheng Tsai, Ying-Ting Tseng, Meng-Shih Wu, Wen-Shan Liu, Hoi-Ian Lam, Jei-Hwa Yu, Susan E. Nozell & Etty N. Benveniste. (2017) Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo . Oncotarget 8:11, pages 18031-18049.
Crossref
Xue-Feng Ding, He-Jun Wang, Lu Qian, Zeng-Yao Hu, Shu-Fang Feng, Yan Wu, Hai-Hong Yang, Hai-Tao Wu, Wen-Hong Fan & Ming Fan. (2017) Cpne5 is Involved in Regulating Rodent Anxiety Level. CNS Neuroscience & Therapeutics 23:3, pages 266-268.
Crossref
Sira A. Franchi, Veronica Astro, Romina Macco, Diletta Tonoli, Jean-Vianney Barnier, Martina Botta & Ivan de Curtis. (2016) Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons. Frontiers in Cellular Neuroscience 10.
Crossref
Emily E. Rosowski, Qing Deng, Nancy P. Keller & Anna Huttenlocher. (2016) Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish. The Journal of Immunology 197:12, pages 4780-4790.
Crossref
Roberta Pennucci, Francesca Talpo, Veronica Astro, Valentina Montinaro, Lorenzo Morè, Marco Cursi, Valerio Castoldi, Sara Chiaretti, Veronica Bianchi, Silvia Marenna, Marco Cambiaghi, Diletta Tonoli, Letizia Leocani, Gerardo Biella, Patrizia D'Adamo & Ivan de Curtis. (2015) Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks. Cerebral Cortex, pages bhv274.
Crossref
Simona Tivodar, Katerina Kalemaki, Zouzana Kounoupa, Marina Vidaki, Kostas Theodorakis, Myrto Denaxa, Nicoletta Kessaris, Ivan de Curtis, Vassilis Pachnis & Domna Karagogeos. (2015) Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cerebral Cortex 25:9, pages 2370-2382.
Crossref
Marioara F. Ciuculescu, Shin-Young Park, Kimberly Canty, Ronald Mathieu, Leslie E. Silberstein & David A. Williams. (2015) Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo. Blood 125:20, pages 3105-3113.
Crossref
Roberta Azzarelli, Thomas Kerloch & Emilie Pacary. (2015) Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies. Frontiers in Cellular Neuroscience 8.
Crossref
Trisha R. Stankiewicz & Daniel A. Linseman. (2014) Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration. Frontiers in Cellular Neuroscience 8.
Crossref
Ivan de Curtis. (2014) Roles of Rac1 and Rac3 GTPases during the development of cortical and hippocampal GABAergic interneurons. Frontiers in Cellular Neuroscience 8.
Crossref
Bhavin Shah & Andreas W. Püschel. (2014) In vivo functions of small GTPases in neocortical development . Biological Chemistry 395:5, pages 465-476.
Crossref
Valentina Vaghi, Roberta Pennucci, Francesca Talpo, Sara Corbetta, Valentina Montinaro, Cinzia Barone, Laura Croci, Paolo Spaiardi, G. Giacomo Consalez, Gerardo Biella & Ivan de Curtis. (2014) Rac1 and Rac3 GTPases Control Synergistically the Development of Cortical and Hippocampal GABAergic Interneurons. Cerebral Cortex 24:5, pages 1247-1258.
Crossref
Arun Murali & Krishnaraj Rajalingam. (2013) Small Rho GTPases in the control of cell shape and mobility. Cellular and Molecular Life Sciences 71:9, pages 1703-1721.
Crossref
Lucy E. Dalton, Jivko Kamarashev, Irene Barinaga-Rementeria Ramirez, Gavin White, Angeliki Malliri & Adam Hurlstone. (2013) Constitutive Rac Activation Is Not Sufficient to Initiate Melanocyte Neoplasia but Accelerates Malignant Progression. Journal of Investigative Dermatology 133:6, pages 1572-1581.
Crossref
Anika Steffen, Markus Ladwein, Georgi A. Dimchev, Anke Hein, Lisa Schwenkmezger, Stefan Arens, Kathrin I. Ladwein, J. Margit Holleboom, Florian Schur, J. Victor Small, Janett Schwarz, Ralf Gerhard, Jan Faix, Theresia E. B. Stradal, Cord Brakebusch & Klemens Rottner. (2013) Rac function is critical for cell migration but not required for spreading and focal adhesion formation. Journal of Cell Science.
Crossref
Vijayalakshmi Thamilselvan, Mani Menon & Sivagnanam Thamilselvan. (2011) Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury. Urological Research 40:4, pages 415-423.
Crossref
Christian Gonzalez-Billault, Pablo Muñoz-Llancao, Daniel R. Henriquez, José Wojnacki, Cecilia Conde & Alfredo Caceres. (2012) The role of small GTPases in neuronal morphogenesis and polarity. Cytoskeleton 69:7, pages 464-485.
Crossref
Diamantis G. KonstantinidisSuvarnamala PushkaranJames F. JohnsonJose A. CancelasStefanos Manganaris, Chad E. Harris, David A. Williams, Yi ZhengTheodosia A. Kalfa. (2012) Signaling and cytoskeletal requirements in erythroblast enucleation. Blood 119:25, pages 6118-6127.
Crossref
Eva Wertheimer, Alvaro Gutierrez-Uzquiza, Cinthia Rosemblit, Cynthia Lopez-Haber, Maria Soledad Sosa & Marcelo G. Kazanietz. (2012) Rac signaling in breast cancer: A tale of GEFs and GAPs. Cellular Signalling 24:2, pages 353-362.
Crossref
Steven W. Lane, Serena De VitaKylie A. Alexander, Ruchan KaramanMichael D. MilsomAdrienne M. DorranceAmy Purdon, Leeann Louis, Mary L. Bouxsein & David A. Williams. (2012) Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood 119:3, pages 736-744.
Crossref
Subhanjan Mondal, Saurabh Ghosh-Roy, Fabien Loison, Yitang Li, Yonghui Jia, Chad Harris, David A. Williams & Hongbo R. Luo. (2011) PTEN Negatively Regulates Engulfment of Apoptotic Cells by Modulating Activation of Rac GTPase. The Journal of Immunology 187:11, pages 5783-5794.
Crossref
Roberta Pennucci, Stefania Tavano, Diletta Tonoli, Sara Gualdoni & Ivan de Curtis. (2011) Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus. PLoS ONE 6:9, pages e24819.
Crossref
Veronica Basso, Sara Corbetta, Sara Gualdoni, Diletta Tonoli, Pietro Luigi Poliani, Francesca Sanvito, Claudio Doglioni, Anna Mondino & Ivan de Curtis. (2011) Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune‐competence development. European Journal of Immunology 41:5, pages 1410-1419.
Crossref
Abdelhafid Saci, Lewis C. Cantley & Christopher L. Carpenter. (2011) Rac1 Regulates the Activity of mTORC1 and mTORC2 and Controls Cellular Size. Molecular Cell 42:1, pages 50-61.
Crossref
Rachel McMullan & Stephen J. Nurrish. (2011) The RHO-1 RhoGTPase Modulates Fertility and Multiple Behaviors in Adult C. elegans. PLoS ONE 6:2, pages e17265.
Crossref
Michael W. Nestor, Xiang Cai, Michele R. Stone, Robert J. Bloch & Scott M. Thompson. (2011) The Actin Binding Domain of βI-Spectrin Regulates the Morphological and Functional Dynamics of Dendritic Spines. PLoS ONE 6:1, pages e16197.
Crossref
Takashi Itokowa, Mei-ling Zhu, Nancy Troiano, Jessica Bian, Tustomu Kawano & Karl Insogna. (2010) Osteoclasts Lacking Rac2 Have Defective Chemotaxis and Resorptive Activity. Calcified Tissue International 88:1, pages 75-86.
Crossref
Haymanti Bhanot, Ashley M. Young, Jean H. Overmeyer & William A. Maltese. (2010) Induction of Nonapoptotic Cell Death by Activated Ras Requires Inverse Regulation of Rac1 and Arf6. Molecular Cancer Research 8:10, pages 1358-1374.
Crossref
Ya-Jing Peng, Wei-Qi He, Jing Tang, Tao Tao, Chen Chen, Yun-Qian Gao, Wen-Cheng Zhang, Xue-Yan He, Yu-Yuan Dai, Nian-Chun Zhu, Ning Lv, Cheng-Hai Zhang, Yan-Ning Qiao, Li-Ping Zhao, Xiang Gao & Min-Sheng Zhu. (2010) Trio Is a Key Guanine Nucleotide Exchange Factor Coordinating Regulation of the Migration and Morphogenesis of Granule Cells in the Developing Cerebellum. Journal of Biological Chemistry 285:32, pages 24834-24844.
Crossref
Sabina Tahirovic, Farida Hellal, Dorothee Neukirchen, Robert Hindges, Boyan K. Garvalov, Kevin C. Flynn, Theresia E. Stradal, Anna Chrostek-Grashoff, Cord Brakebusch & Frank Bradke. (2010) Rac1 Regulates Neuronal Polarization through the WAVE Complex. The Journal of Neuroscience 30:20, pages 6930-6943.
Crossref
Thomas U Greiner, Gokul Kesavan, Anders Ståhlberg & Henrik Semb. (2009) Rac1 regulates pancreatic islet morphogenesis. BMC Developmental Biology 9:1.
Crossref
Amra Hajdo-Milasinovic, Rob A. van der Kammen, Zvezdana Moneva & John G. Collard. (2009) Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling. Journal of Cell Science 122:12, pages 2127-2136.
Crossref
Sara Corbetta, Sara Gualdoni, Gabriele Ciceri, Marta Monari, Emanuela Zuccaro, Victor L. J. Tybulewicz & Ivan De Curtis. (2009) Essential role of Rac1 and Rac3 GTPases in neuronal development. The FASEB Journal 23:5, pages 1347-1357.
Crossref
Shuji Ueda, Tohru Kataoka & Takaya Satoh. (2008) Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells. Biology of the Cell 100:11, pages 645-661.
Crossref
Katherine Karakoula, Blanca Suarez-Merino, Samantha Ward, Kim P. Phipps, William Harkness, Richard Hayward, Dominic Thompson, Thomas S. Jacques, Brian Harding, John Beck, David G. T. Thomas & Tracy J. Warr. (2008) Real-time quantitative PCR analysis of pediatric ependymomas identifies novel candidate genes including TPR at 1q25 and CHIBBY at 22q12-q13 . Genes, Chromosomes and Cancer 47:11, pages 1005-1022.
Crossref
JoAnne E. Waters, Megan V. Astle, Lisa M. Ooms, Demis Balamatsias, Rajendra Gurung & Christina A. Mitchell. (2008) P-Rex1 – a multidomain protein that regulates neurite differentiation. Journal of Cell Science 121:17, pages 2892-2903.
Crossref
Sarah J. Heasman & Anne J. Ridley. (2008) Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nature Reviews Molecular Cell Biology 9:9, pages 690-701.
Crossref
Markus Ladwein & Klemens Rottner. (2008) On the Rho'd: The regulation of membrane protrusions by Rho-GTPases. FEBS Letters 582:14, pages 2066-2074.
Crossref
Sarah DonaldTrevor HumbyIan FyfeAnne Segonds-PichonSimon A. Walker, Simon R. AndrewsW. John CoadwellPiers Emson, Lawrence S. WilkinsonHeidi C. E. Welch. (2008) P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination. Proceedings of the National Academy of Sciences 105:11, pages 4483-4488.
Crossref
Olivier C. Pertz, Yingchun Wang, Feng Yang, Wei Wang, Laurie J. Gay, Marina A. Gristenko, Therese R. Clauss, David J. Anderson, Tao Liu, Kenneth J. Auberry, David G. CampIIII, Richard D. Smith & Richard L. Klemke. (2008) Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network. Proceedings of the National Academy of Sciences 105:6, pages 1931-1936.
Crossref
David A. Williams, Yi Zheng & Jose A. Cancelas. 2008. Small GTPases in Disease, Part B. Small GTPases in Disease, Part B 365 393 .
Emily K. Thomas, Jose A. Cancelas, Hee-Don Chae, Adrienne D. Cox, Patricia J. Keller, Danilo Perrotti, Paolo Neviani, Brian J. Druker, Kenneth D.R. Setchell, Yi Zheng, Chad E. Harris & David A. Williams. (2007) Rac Guanosine Triphosphatases Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease. Cancer Cell 12:5, pages 467-478.
Crossref
Saskia I. J. Ellenbroek & John G. Collard. (2007) Rho GTPases: functions and association with cancer. Clinical & Experimental Metastasis 24:8, pages 657-672.
Crossref
Sara Gualdoni, Chiara Albertinazzi, Sara Corbetta, Flavia Valtorta & Ivan Curtis. (2007) Normal levels of Rac1 are important for dendritic but not axonal development in hippocampal neurons. Biology of the Cell 99:8, pages 455-464.
Crossref
Michael Tscharntke, Ruth Pofahl, Anna Chrostek-Grashoff, Neil Smyth, Carien Niessen, Catherin Niemann, Benedikt Hartwig, Volker Herzog, Helmut W. Klein, Thomas Krieg, Cord Brakebusch & Ingo Haase. (2007) Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1. Journal of Cell Science 120:8, pages 1480-1490.
Crossref
Lei Chen, Guanghong Liao, Ronald R. Waclaw, Kevin A. Burns, Diana Linquist, Kenneth Campbell, Yi Zheng & Chia-Yi Kuan. (2007) Rac1 Controls the Formation of Midline Commissures and the Competency of Tangential Migration in Ventral Telencephalic Neurons. The Journal of Neuroscience 27:14, pages 3884-3893.
Crossref
Xosé R. Bustelo, Vincent Sauzeau & Inmaculada M. Berenjeno. (2007) GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo. BioEssays 29:4, pages 356-370.
Crossref
Amra Hajdo-Milašinović, Saskia I. J. Ellenbroek, Saskia van Es, Babet van der Vaart & John G. Collard. (2007) Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells. Journal of Cell Science 120:4, pages 555-566.
Crossref
Lei Wang & Yi Zheng. (2007) Cell type-specific functions of Rho GTPases revealed by gene targeting in mice. Trends in Cell Biology 17:2, pages 58-64.
Crossref
Anthony Boureux, Emmanuel Vignal, Sandrine Faure & Philippe Fort. (2007) Evolution of the Rho Family of Ras-Like GTPases in Eukaryotes. Molecular Biology and Evolution 24:1, pages 203-216.
Crossref
Theodosia A. KalfaSuvarnamala PushkaranNarla MohandasJohn H. HartwigVelia M. FowlerJames F. JohnsonClinton H. JoinerDavid A. WilliamsYi Zheng. (2006) Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood 108:12, pages 3637-3645.
Crossref
Jessica J Nadler, Fei Zou, Hanwen Huang, Sheryl S Moy, Jean Lauder, Jacqueline N Crawley, David W Threadgill, Fred A Wright & Terry R Magnuson. (2006) Large-Scale Gene Expression Differences Across Brain Regions and Inbred Strains Correlate With a Behavioral Phenotype. Genetics 174:3, pages 1229-1236.
Crossref
Jose A. Cancelas, Michael Jansen & David A. Williams. (2006) The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization. Experimental Hematology 34:8, pages 976-985.
Crossref
Ann P. Wheeler, Claire M. Wells, Stephen D. Smith, Francisco M. Vega, Robert B. Henderson, Victor L. Tybulewicz & Anne J. Ridley. (2006) Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. Journal of Cell Science 119:13, pages 2749-2757.
Crossref
Ulla Knaus. (2006) Rac3. AfCS-Nature Molecule Pages.
Crossref
Ivan de Curtis & Simona Paris. 2005. GTPases Regulating Membrane Dynamics. GTPases Regulating Membrane Dynamics 267 278 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.