Advanced search
Publication Cover
Molecular and Cellular Biology Volume 25, 2005 - Issue 14
Submit an article Journal homepage
9
Views
45
CrossRef citations to date
0
Altmetric
Signal Transduction

c-Src-Mediated Phosphorylation of TRIP6 Regulates Its Function in Lysophosphatidic Acid-Induced Cell Migration

Yun-Ju Lai1 Department of Cell Biology
,
Chen-Shan Chen1 Department of Cell Biology
,
Weei-Chin Lin1 Department of Cell Biology;2 Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama35294-0005
&
Fang-Tsyr Lin1 Department of Cell BiologyCorrespondence[email protected]
Pages 5859-5868 | Received 13 Sep 2004, Accepted 11 Apr 2005, Published online: 27 Mar 2023

Citations (45)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Yang Xiao, Vivian Y. Lin, Shi Ke, Gregory E. Lin, Fang-Tsyr Lin & Weei-Chin Lin. (2014) 14-3-3τ Promotes Breast Cancer Invasion and Metastasis by Inhibiting RhoGDIα. Molecular and Cellular Biology 34:14, pages 2635-2649.
Read now
Victor T. G. Lin, Vivian Y. Lin, Yun-Ju Lai, Chen-Shan Chen, Kang Liu, Weei-Chin Lin & Fang-Tsyr Lin. (2013) TRIP6 Regulates p27KIP1 To Promote Tumorigenesis. Molecular and Cellular Biology 33:7, pages 1394-1409.
Read now
Yun-Ju Lai, Victor T. G. Lin, Ying Zheng, Etty N. Benveniste & Fang-Tsyr Lin. (2010) The Adaptor Protein TRIP6 Antagonizes Fas-Induced Apoptosis but Promotes Its Effect on Cell Migration. Molecular and Cellular Biology 30:23, pages 5582-5596.
Read now

Articles from other publishers (42)

Yun Yang, Xiu-Ming Li, Jing-Ru Wang, Yan Li, Wen-Long Ye, Yi Wang, Yu-Xuan Liu, Zhi-Yong Deng, Wen-Juan Gan & Hua Wu. (2022) TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis. Journal of Inflammation 19:1.
Crossref
Johann Bauer, Erich Gombocz, Herbert Schulz, Jens Hauslage & Daniela Grimm. (2021) Interaction Network Provides Clues on the Role of BCAR1 in Cellular Response to Changes in Gravity. Computation 9:8, pages 81.
Crossref
Barry J. Thompson. (2020) YAP/TAZ: Drivers of Tumor Growth, Metastasis, and Resistance to Therapy. BioEssays 42:5, pages 1900162.
Crossref
C. Chris Yun. (2019) Lysophosphatidic Acid and Autotaxin-associated Effects on the Initiation and Progression of Colorectal Cancer. Cancers 11:7, pages 958.
Crossref
Olga Suckau, Isabel Gross, Sandra Schrötter, Fan Yang, Jiankai Luo, Andreas Wree, Jerold Chun, David Baska, Jan Baumgart, Kuniyuki Kano, Junken Aoki & Anja U. Bräuer. (2019) LPA 1 , LPA 2 , LPA 4 , and LPA 6 receptor expression during mouse brain development . Developmental Dynamics 248:5, pages 375-395.
Crossref
Michael H. Kogut & Elizabeth Santin. 2019. Food Safety in Poultry Meat Production. Food Safety in Poultry Meat Production 161 189 .
Thibault Robin, Amos Bairoch, Markus Müller, Frédérique Lisacek & Lydie Lane. (2018) Large-Scale Reanalysis of Publicly Available HeLa Cell Proteomics Data in the Context of the Human Proteome Project. Journal of Proteome Research 17:12, pages 4160-4170.
Crossref
Fang Yang & Guo-Xun Chen. (2018) Production of extracellular lysophosphatidic acid in the regulation of adipocyte functions and liver fibrosis. World Journal of Gastroenterology 24:36, pages 4132-4151.
Crossref
Yun-Ju Lai, Jui-Cheng Tsai, Ying-Ting Tseng, Meng-Shih Wu, Wen-Shan Liu, Hoi-Ian Lam, Jei-Hwa Yu, Susan E. Nozell & Etty N. Benveniste. (2017) Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo . Oncotarget 8:11, pages 18031-18049.
Crossref
Silvia Anahi Valdés-Rives & Aliesha González-Arenas. (2017) Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development. Mediators of Inflammation 2017, pages 1-15.
Crossref
Michael H. Kogut & James A. Byrd. 2017. Producing Safe Eggs. Producing Safe Eggs 209 234 .
Sara A. Knowlden, Sara E. Hillman, Timothy J. Chapman, Renukadevi Patil, Duane D. Miller, Gabor Tigyi & Steve N. Georas. (2016) Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology 54:3, pages 402-409.
Crossref
Fang-Tsyr Lin, Vivian Y Lin, Victor T G Lin & Weei-Chin Lin. (2016) TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation. Cell Discovery 2:1.
Crossref
Anjum Riaz, Ying Huang & Staffan Johansson. (2016) G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling. International Journal of Molecular Sciences 17:2, pages 215.
Crossref
Yanli Yan, Li Ma, Xiaoxu Zhou, Murugavel Ponnusamy, Jinhua Tang, Michelle A. Zhuang, Evelyn Tolbert, Georgia Bayliss, Jianwen Bai & Shougang Zhuang. (2016) Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis. Kidney International 89:1, pages 68-81.
Crossref
Wenlin Deng, Yasuhiro Kimura, Veeresh Gududuru, Wenjie Wu, Andrea Balogh, Erzsebet Szabo, Karin Emmons Thompson, C. Ryan Yates, Louisa Balazs, Leonard R. Johnson, Duane D. Miller, Jur Strobos, W. Shannon McCool & Gabor J. Tigyi. (2015) Mitigation of the Hematopoietic and Gastrointestinal Acute Radiation Syndrome by Octadecenyl Thiophosphate, a Small Molecule Mimic of Lysophosphatidic Acid. Radiation Research 183:4, pages 465-475.
Crossref
Nela Pavlíková, Irena Bartoňová, Kamila Balušíková, Dana Kopperova, Petr Halada & Jan Kovář. (2015) Differentially expressed proteins in human MCF-7 breast cancer cells sensitive and resistant to paclitaxel. Experimental Cell Research 333:1, pages 1-10.
Crossref
Yun-Ju Lai, Ming-Yang Li, Cheng-Yao Yang, Kao-Hua Huang, Jui-Cheng Tsai & Tsu-Wei Wang. (2014) TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. Developmental Dynamics 243:9, pages 1130-1142.
Crossref
Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel & Jerold Chun. (2014) Lysophospholipid receptor nomenclature review: IUPHAR Review 8. British Journal of Pharmacology 171:15, pages 3575-3594.
Crossref
Yun C. Yung, Nicole C. Stoddard & Jerold Chun. (2014) LPA receptor signaling: pharmacology, physiology, and pathophysiology. Journal of Lipid Research 55:7, pages 1192-1214.
Crossref
Gye Young Park, Yong Gyu Lee, Evgeny Berdyshev, Sharmilee Nyenhuis, Jian Du, Panfeng Fu, Irina A. Gorshkova, Yongchao Li, Sangwoon Chung, Manjula Karpurapu, Jing Deng, Ravi Ranjan, Lei Xiao, H. Ari Jaffe, Susan J. Corbridge, Elizabeth A. B. Kelly, Nizar N. Jarjour, Jerold Chun, Glenn D. Prestwich, Eleanna Kaffe, Ioanna Ninou, Vassilis Aidinis, Andrew J. Morris, Susan S. Smyth, Steven J. Ackerman, Viswanathan Natarajan & John W. Christman. (2013) Autotaxin Production of Lysophosphatidic Acid Mediates Allergic Asthmatic Inflammation. American Journal of Respiratory and Critical Care Medicine 188:8, pages 928-940.
Crossref
Jie Fei, Jihong Li, Sunan Shen & Weidong Zhou. (2013) Characterization of TRIP6-dependent nasopharyngeal cancer cell migration. Tumor Biology 34:4, pages 2329-2335.
Crossref
C. Chris Yun & Peijian He. 2013. Lysophospholipid Receptors. Lysophospholipid Receptors 507 527 .
Hope Mirendil, Mu‐En Lin & Jerold Chun. 2013. Lysophospholipid Receptors. Lysophospholipid Receptors 1 39 .
Gyöngyi N. Kiss, James I. Fells, Renuka Gupte, Sue-Chin Lee, Jianxiong Liu, Nóra Nusser, Keng G. Lim, Ramesh M. Ray, Fang-Tsyr Lin, Abby L. Parrill, Balázs Sümegi, Duane D. Miller & Gabor Tigyi. (2012) Virtual Screening for LPA 2 -Specific Agonists Identifies a Nonlipid Compound with Antiapoptotic Actions . Molecular Pharmacology 82:6, pages 1162-1173.
Crossref
Semjon Willier, Elke Butt, Günther H.S. Richter, Stefan Burdach & Thomas G.P. Grunewald. (2011) Defining the role of TRIP6 in cell physiology and cancer. Biology of the Cell 103:12, pages 573-591.
Crossref
Victor T.G. Lin & Fang-Tsyr Lin. (2011) TRIP6: An adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. Cellular Signalling 23:11, pages 1691-1697.
Crossref
Brooke K. McMichael, Stephanie M. Meyer & Beth S. Lee. (2010) c-Src-mediated Phosphorylation of Thyroid Hormone Receptor-interacting Protein 6 (TRIP6) Promotes Osteoclast Sealing Zone Formation. Journal of Biological Chemistry 285:34, pages 26641-26651.
Crossref
Markus E. Diefenbacher, Margarethe Litfin, Peter Herrlich & Olivier Kassel. (2010) The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor. Molecular and Cellular Endocrinology 320:1-2, pages 58-66.
Crossref
Ji Woong ChoiDeron R. HerrKyoko NoguchiYun C. YungChang-Wook LeeTetsuji MutohMu-En LinSiew T. TeoKristine E. ParkAlycia N. MosleyJerold Chun. (2010) LPA Receptors: Subtypes and Biological Actions. Annual Review of Pharmacology and Toxicology 50:1, pages 157-186.
Crossref
Tara C. Smith, Zhiyou Fang & Elizabeth J. Luna. (2010) Novel interactors and a role for supervillin in early cytokinesis. Cytoskeleton, pages NA-NA.
Crossref
Shuyu E, Yun-Ju Lai, Ryoko Tsukahara, Chen-Shan Chen, Yuko Fujiwara, Junming Yue, Jei-Hwa Yu, Huazhang Guo, Akio Kihara, Gábor Tigyi & Fang-Tsyr Lin. (2009) Lysophosphatidic Acid 2 Receptor-mediated Supramolecular Complex Formation Regulates Its Antiapoptotic Effect. Journal of Biological Chemistry 284:21, pages 14558-14571.
Crossref
Eric Chastre, Mahmoud Abdessamad, Alexey Kruglov, Erik Bruyneel, Marc Bracke, Yolande Di Gioia, Mary C. Beckerle, Frans Roy & Larissa Kotelevets. (2008) TRIP6, a novel molecular partner of the MAGI‐1 scaffolding molecule, promotes invasiveness. The FASEB Journal 23:3, pages 916-928.
Crossref
Jessica L. Crowley, Tara C. Smith, Zhiyou Fang, Norio Takizawa & Elizabeth J. Luna. (2009) Supervillin Reorganizes the Actin Cytoskeleton and Increases Invadopodial Efficiency. Molecular Biology of the Cell 20:3, pages 948-962.
Crossref
William J. Valentine, Yuko Fujiwara, Ryoko Tsukahara & Gabor Tigyi. (2008) Lysophospholipid signaling: Beyond the EDGs. Biochimica et Biophysica Acta (BBA) - General Subjects 1780:3, pages 597-605.
Crossref
Seema Khurana, Alok Tomar, Sudeep P. George, Yaohong Wang, Mohammad Rizwan Siddiqui, Huazhang Guo, Gabor Tigyi & Sijo Mathew. (2008) Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia. Experimental Cell Research 314:3, pages 530-542.
Crossref
Chen-Yu Bai, Miho Ohsugi, Yoshinori Abe & Tadashi Yamamoto. (2007) ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions. Journal of Cell Science 120:16, pages 2828-2837.
Crossref
Yun-Ju Lai, Weei-Chin Lin & Fang-Tsyr Lin. (2007) PTPL1/FAP-1 Negatively Regulates TRIP6 Function in Lysophosphatidic Acid-induced Cell Migration. Journal of Biological Chemistry 282:33, pages 24381-24387.
Crossref
Wenlin Deng, Shuyu E, Ryoko Tsukahara, William J. Valentine, Gangadhar Durgam, Veeresa Gududuru, Louisa Balazs, Venkatraman Manickam, Marcello Arsura, Lester Vanmiddlesworth, Leonard R. Johnson, Abby L. Parrill, Duane D. Miller & Gabor Tigyi. (2007) The Lysophosphatidic Acid Type 2 Receptor Is Required for Protection Against Radiation-Induced Intestinal Injury. Gastroenterology 132:5, pages 1834-1851.
Crossref
Micah J. Worley, George S. Nieman, Kaoru Geddes & Fred Heffron. (2006) Salmonella typhimurium disseminates within its host by manipulating the motility of infected cells . Proceedings of the National Academy of Sciences 103:47, pages 17915-17920.
Crossref
Qin Wang, Roujian Lu, Jiali Zhao & Lee E. Limbird. (2006) Arrestin Serves as a Molecular Switch, Linking Endogenous α2-Adrenergic Receptor to SRC-dependent, but Not SRC-independent, ERK Activation. Journal of Biological Chemistry 281:36, pages 25948-25955.
Crossref
Norio TakizawaTara C. SmithThomas NeblJessica L. CrowleyStephen J. PalmieriLawrence M. Lifshitz, Anka G. EhrhardtLaura M. Hoffman, Mary C. Beckerle & Elizabeth J. Luna. (2006) Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. Journal of Cell Biology 174:3, pages 447-458.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.