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Molecular and Cellular Biology Volume 25, 2005 - Issue 21
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Intracellular Trafficking

Long-Chain Base Kinase Lcb4 Is Anchored to the Membrane through Its Palmitoylation by Akr1

Akio KiharaDepartment of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo060-0812, Japan
,
Fumiko KurotsuDepartment of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo060-0812, Japan
,
Takamitsu SanoDepartment of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo060-0812, Japan
,
Soichiro IwakiDepartment of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo060-0812, Japan
&
Yasuyuki IgarashiDepartment of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo060-0812, JapanCorrespondence[email protected]
Pages 9189-9197 | Received 24 Feb 2005, Accepted 05 Aug 2005, Published online: 27 Mar 2023

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Naoya Seki, Keisuke Mori, Takuya Kitamura, Masatoshi Miyamoto & Akio Kihara. (2019) Yeast Mpo1 Is a Novel Dioxygenase That Catalyzes the α-Oxidation of a 2-Hydroxy Fatty Acid in an Fe2+-Dependent Manner. Molecular and Cellular Biology 39:5.
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Articles from other publishers (35)

Yuqi Zhang, Ziran Qin, Wenhuan Sun, Feng Chu & Fangfang Zhou. (2021) Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases. Frontiers in Immunology 12.
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Hongguang Pang, Qi Yan, Shuliang Zhao, Fang He, Jianfeng Xu, Baoxiu Qi & Yuxing Zhang. (2019) Knockout of the S-acyltransferase Gene, PbPAT14, Confers the Dwarf Yellowing Phenotype in First Generation Pear by ABA Accumulation. International Journal of Molecular Sciences 20:24, pages 6347.
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Peter J. Harrison, Teresa M. Dunn & Dominic J. Campopiano. (2018) Sphingolipid biosynthesis in man and microbes. Natural Product Reports 35:9, pages 921-954.
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Stijn Wittouck & Vera van Noort. (2017) Correlated duplications and losses in the evolution of palmitoylation writer and eraser families. BMC Evolutionary Biology 17:1.
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Sheila A. Kitchen, Angela Z. Poole & Virginia M. Weis. (2017) Sphingolipid Metabolism of a Sea Anemone Is Altered by the Presence of Dinoflagellate Symbionts. The Biological Bulletin 233:3, pages 242-254.
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Takuya Kitamura, Naoya Seki & Akio Kihara. (2017) Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. Proceedings of the National Academy of Sciences 114:13.
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Yaxiao Li & Baoxiu Qi. (2017) Progress toward Understanding Protein S-acylation: Prospective in Plants. Frontiers in Plant Science 8.
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Hiroshi Makuta, Keisuke Obara & Akio Kihara. (2016) Loop 5 region is important for the activity of the long-chain base transporter Rsb1. Journal of Biochemistry, pages mvw059.
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Gi-Wook Hwang, Toru Fukumitsu, Yousuke Ogiwara, Tsutomu Takahashi, Nobuhiko Miura, Shusuke Kuge & Akira Naganuma. (2016) Whi2 enhances methylmercury toxicity in yeast via inhibition of Akr1 palmitoyltransferase activity. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:6, pages 1326-1333.
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Yuanwei Zhang, Qingqing Zheng, Congcong Sun, Jinxing Song, Lina Gao, Shizhu Zhang, Alberto Muñoz, Nick D. Read & Ling Lu. (2016) Palmitoylation of the Cysteine Residue in the DHHC Motif of a Palmitoyl Transferase Mediates Ca2+ Homeostasis in Aspergillus. PLOS Genetics 12:4, pages e1005977.
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Natsuki Kondo, Yusuke Ohno, Maki Yamagata, Takashi Obara, Naoya Seki, Takuya Kitamura, Tatsuro Naganuma & Akio Kihara. (2014) Identification of the phytosphingosine metabolic pathway leading to odd-numbered fatty acids. Nature Communications 5:1.
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Takeshi Wakashima, Kensuke Abe & Akio Kihara. (2014) Dual Functions of the Trans-2-Enoyl-CoA Reductase TER in the Sphingosine 1-Phosphate Metabolic Pathway and in Fatty Acid Elongation. Journal of Biological Chemistry 289:36, pages 24736-24748.
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Surya P. Manandhar, Erika N. Calle & Editte Gharakhanian. (2014) Distinct Palmitoylation Events at the Amino-terminal Conserved Cysteines of Env7 Direct Its Stability, Localization, and Vacuolar Fusion Regulation in S. cerevisiae. Journal of Biological Chemistry 289:16, pages 11431-11442.
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Matthew J Edmonds & Alan Morgan. (2014) A systematic analysis of protein palmitoylation in Caenorhabditis elegans. BMC Genomics 15:1, pages 841.
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Yusuke Ohno, Atsushi Kashio, Ren Ogata, Akihiro Ishitomi, Yuki Yamazaki & Akio Kihara. (2012) Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system. Molecular Biology of the Cell 23:23, pages 4543-4551.
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Piers A. Hemsley & Claire S. Grierson. (2011) The Ankyrin Repeats and DHHC S-acyl Transferase Domain of AKR1 Act Independently to Regulate Switching from Vegetative to Mating States in Yeast. PLoS ONE 6:12, pages e28799.
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Amy F. Roth, Irene Papanayotou & Nicholas G. Davis. (2011) The yeast kinase Yck2 has a tripartite palmitoylation signal. Molecular Biology of the Cell 22:15, pages 2702-2715.
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Le-Le Hu, Si-Bao Wan, Shen Niu, Xiao-He Shi, Hai-Peng Li, Yu-Dong Cai & Kuo-Chen Chou. (2011) Prediction and analysis of protein palmitoylation sites. Biochimie 93:3, pages 489-496.
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Irene Papanayotou, Beimeng Sun, Amy F. Roth & Nicholas G. Davis. (2010) Protein aggregation induced during glass bead lysis of yeast. Yeast 27:10, pages 801-816.
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Haitong Hou, Arun T. John Peter, Christoph Meiringer, Kanagaraj Subramanian & Christian Ungermann. (2009) Analysis of DHHC Acyltransferases Implies Overlapping Substrate Specificity and a Two-Step Reaction Mechanism. Traffic 10:8, pages 1061-1073.
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Ming Chen, Edgar B. Cahoon, Mariana Saucedo-García, Javier Plasencia & Marina Gavilanes-Ruíz. 2009. Lipids in Photosynthesis. Lipids in Photosynthesis 77 115 .
Debdyuti Mukhopadhyay, Kate S. Howell, Howard Riezman & Guido Capitani. (2008) Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in Vitro. Journal of Biological Chemistry 283:29, pages 20159-20169.
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Marissa J. Nadolski & Maurine E. Linder. (2007) Protein lipidation. FEBS Journal 274:20, pages 5202-5210.
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Soichiro Iwaki, Takamitsu Sano, Tomoko Takagi, Masako Osumi, Akio Kihara & Yasuyuki Igarashi. (2007) Intracellular Trafficking Pathway of Yeast Long-chain Base Kinase Lcb4, from Its Synthesis to Its Degradation. Journal of Biological Chemistry 282:39, pages 28485-28492.
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Akio Kihara, Susumu Mitsutake, Yukiko Mizutani & Yasuyuki Igarashi. (2007) Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate. Progress in Lipid Research 46:2, pages 126-144.
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L. Ashley Cowart & Lina M. Obeid. (2007) Yeast sphingolipids: Recent developments in understanding biosynthesis, regulation, and function. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1771:3, pages 421-431.
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Maurine E. Linder & Robert J. Deschenes. (2007) Palmitoylation: policing protein stability and traffic. Nature Reviews Molecular Cell Biology 8:1, pages 74-84.
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Nitai C. Hait, Carole A. Oskeritzian, Steven W. Paugh, Sheldon Milstien & Sarah Spiegel. (2006) Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases. Biochimica et Biophysica Acta (BBA) - Biomembranes 1758:12, pages 2016-2026.
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Cheryl Budde, Marissa J. Schoenfish, Maurine E. Linder & Robert J. Deschenes. (2006) Purification and characterization of recombinant protein acyltransferases. Methods 40:2, pages 143-150.
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Amy F. Roth, Junmei Wan, William N. Green, John R. Yates & Nicholas G. Davis. (2006) Proteomic identification of palmitoylated proteins. Methods 40:2, pages 135-142.
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David A. Mitchell, Anant Vasudevan, Maurine E. Linder & Robert J. Deschenes. (2006) Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases. Journal of Lipid Research 47:6, pages 1118-1127.
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Amy F. Roth, Junmei Wan, Aaron O. Bailey, Beimeng Sun, Jason A. Kuchar, William N. Green, Brett S. Phinney, John R. YatesIIIIII & Nicholas G. Davis. (2006) Global Analysis of Protein Palmitoylation in Yeast. Cell 125:5, pages 1003-1013.
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Yusuke Ohno, Akio Kihara, Takamitsu Sano & Yasuyuki Igarashi. (2006) Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1761:4, pages 474-483.
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Akio Kihara, Yoshihiro Anada & Yasuyuki Igarashi. (2006) Mouse Sphingosine Kinase Isoforms SPHK1a and SPHK1b Differ in Enzymatic Traits Including Stability, Localization, Modification, and Oligomerization. Journal of Biological Chemistry 281:7, pages 4532-4539.
Crossref
Akio Kihara & Yasuyuki Igarashi. 2006. Sphingolipid Biology. Sphingolipid Biology 95 106 .

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